Ahead of the Curve

Author: Shane Crotty
Publisher: Univ of California Press
ISBN: 0520239040
Format: PDF, Docs
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A revealing portrait of one of the most important scientists of the last century reveals David Baltimore's groundbreaking work in molecular biology and, most recently, his search for an AIDS vaccine, as well as his involvement in the anti-war movement and his Nobel Prize.

How to Win the Nobel Prize

Author: J. Michael BISHOP
Publisher: Harvard University Press
ISBN: 0674020979
Format: PDF, Docs
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In 1989 Michael Bishop and Harold Varmus were awarded the Nobel Prize for their discovery that normal genes under certain conditions can cause cancer. In this book, Bishop tells us how he and Varmus made their momentous discovery. More than a lively account of the making of a brilliant scientist, How to Win the Nobel Prize is also a broader narrative combining two major and intertwined strands of medical history: the long and ongoing struggles to control infectious diseases and to find and attack the causes of cancer. Alongside his own story, that of a youthful humanist evolving into an ambivalent medical student, an accidental microbiologist, and finally a world-class researcher, Bishop gives us a fast-paced and engrossing tale of the microbe hunters. It is a narrative enlivened by vivid anecdotes about our deadliest microbial enemies--the Black Death, cholera, syphilis, tuberculosis, malaria, smallpox, HIV--and by biographical sketches of the scientists who led the fight against these scourges. Bishop then provides an introduction for nonscientists to the molecular underpinnings of cancer and concludes with an analysis of many of today's most important science-related controversies--ranging from stem cell research to the attack on evolution to scientific misconduct. How to Win the Nobel Prize affords us the pleasure of hearing about science from a brilliant practitioner who is a humanist at heart. Bishop's perspective will be valued by anyone interested in biomedical research and in the past, present, and future of the battle against cancer. Table of Contents: List of Illustrations Preface 1. The Phone Call 2. Accidental Scientist 3. People and Pestilence 4. Opening the Black Box of Cancer 5. Paradoxical Strife Notes Credits Index Reviews of this book: Despite his book's encouraging title, Bishop--who won a Nobel Prize in Physiology and Medicine in 1989--cautions that "I have not written an instruction manual for pursuit of the prize." Instead, he has written an amiable reflection on the experience of being a Nobelist, intertwined with some history and anecdotes about the award, and balanced by a wide-ranging review of his own career as an "accidental scientist"...Along the way, Bishop reflects on the history of our knowledge of microbes, cancer, the politics of funding research and present-day disenchantment with science. His main purpose in writing this book, Bishop says, is to show that "scientists are supremely human"--which he does with grace and charm. --Publishers Weekly Reviews of this book: How to Win the Nobel Prize is typical Bishop: modest, funny, insightful and offering an extremely clear and brief explanation of the basic scientific achievement that won the 1989 Nobel Prize in physiology or medicine for himself and longtime colleague, Harold Varmus, now president of the Memorial Sloan-Kettering Cancer Center. --David Perlman, San Francisco Chronicle Reviews of this book: In these pages Bishop reveals himself as a good writer blessed with enviable clarity, someone sensible and levelheaded who likes people and is enamored of his science. --John Tyler Bonner, New York Times Book Review Reviews of this book: This is a treasure...Above all, How to Win the Nobel Prize is a civilised book and a lavishly rewarding one. --Roy Herbert, New Scientist Reviews of this book: At its heart this analysis of science and the scientific world is a jewel. How to Win the Nobel Prize is an inspirational book, full of careful analysis and judgement. --John Oxford, Times Higher Education Supplement Reviews of this book: Bishop is a gifted communicator and teacher, and he sets about his task of educating scientists and the public by describing his career in science and science politics...In the end, Bishop's book provides a road map for scientists and the public to build a robust scientific community that serves our society well. --Andreas Trumpp and Daniel Kalman, Nature Cell Biology J. Michael Bishop has written his book 'to show that scientists are supremely human.' The book is also a lucid explanation of how science has been harnessed to fight the human afflictions of cancer and infectious disease. And the story ends with a wide-ranging overview of today's challenges to the scientific enterprise. Overall, a must-read for all those interested in science and scientists--even those with absolutely no interest in winning a Nobel Prize! --Bruce Alberts, President, National Academy of Sciences J. Michael Bishop is that rare scientist who is widely read in literature and poetry. Most importantly, he remembers what he reads and thinks deeply about it, as well as about all else in his rich life. The Nobel Prize he won and richly deserved, his political activism, his understanding of cancer and microbiology, his devotion to the practice of science--all these provide fodder for his writerly craft. Quite a wonderful book! --David Baltimore, Nobel Laureate and President, California Institute of Technology

Ahead of the Curve

Author: Brian Kenny
Publisher: Simon and Schuster
ISBN: 1501106368
Format: PDF, ePub
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“A delight for baseball lovers” (Kirkus Reviews) and “one of the most significant baseball books of the year” (Bob Costas) Ahead of the Curve uses stories from baseball’s present and past to examine why we sometimes choose ignorance over information, and how tradition can trump logic. Forget batting average. Kill the “Win.” Say goodbye to starting pitchers. And please, please stop bunting. MLB Network anchor and commentator Brian Kenny provides “an excellent, entertaining read for the all-around baseball fan” (Library Journal) and shows how baseball has been revolutionized—not destroyed—by analytical thinking. Most people who resist logical thought in baseball preach “tradition” and “respecting the game.” But many of baseball’s traditions go back to the nineteenth century, when the pitcher’s job was to provide the batter with a ball he could hit and fielders played without gloves. Instead of fearing change, Brian Kenny wants fans to think critically, reject outmoded groupthink, and embrace the changes that have come with the sabermetric era. In his entertaining and enlightening book, Kenny discusses why the pitching win-loss record, the Triple Crown, fielding errors, and so-called battling titles should be ignored. He also points out how fossilized sportswriters have been electing the wrong MVP’s and ignoring legitimate candidates for the Hall of Fame; why managers are hired based on their looks; and how the most important position in baseball may just be “Director of Decision Sciences.” “Prepare to have your brain and your assumptions challenged. Guided by data and a deep love of the game, Brian Kenny takes a cutting-edge look at where baseball is and where it is going” (Tom Verducci, Sports Illustrated). Illustrated with unique anecdotes from those who have reshaped the game, Ahead of the Curve is “a great story about the game in the age of information and technology” (Billy Beane).

American Higher Education Transformed 1940 2005

Author: Wilson Smith
Publisher: JHU Press
ISBN: 9780801895852
Format: PDF, ePub
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Wilson Smith and Thomas Bender have assembled an essential reference for policymakers, administrators, and all those interested in the history and sociology of higher education.

Managing Discovery in the Life Sciences

Author: Philip A. Rea
Publisher: Cambridge University Press
ISBN: 1107130905
Format: PDF, Docs
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Addresses in roughly equal measure the science and management behind several recent marketable biomedical innovations.

A History of the Life Sciences Revised and Expanded

Author: Lois N. Magner
Publisher: CRC Press
ISBN: 0824743601
Format: PDF
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A clear and concise survey of the major themes and theories embedded in the history of life science, this book covers the development and significance of scientific methodologies, the relationship between science and society, and the diverse ideologies and current paradigms affecting the evolution and progression of biological studies. The author discusses cell theory, embryology, physiology, microbiology, evolution, genetics, and molecular biology; the Human Genome Project; and genomics and proteomics. Covering the philosophies of ancient civilizations to modern advances in genomics and molecular biology, the book is a unique and comprehensive resource.

A History of Molecular Biology

Author: Michel Morange
Publisher: Harvard University Press
ISBN: 9780674001695
Format: PDF, ePub, Mobi
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Gene therapy, the human genome project, the creation of new varieties of animals and plants have all emanated from molecular biology. Beginning with turn-of-the-century experimentations, this ambitious history covers the story of the transformation of biology over the last 100 years.

Why Did They Kill

Author: Alexander Laban Hinton
Publisher: Univ of California Press
ISBN: 0520241797
Format: PDF, Mobi
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Annotation This is an ethnographic examination and an appraisal of the Cambodian genocide under Pol Pot based on the author's long fieldwork in the area.

Human Trials

Author: Susan Quinn
Publisher: Da Capo Press
ISBN: 9780306820915
Format: PDF
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Susan Quinn's extraordinary story takes the reader into the closed world of experimental "human trials" in which new drugs are developed. Both the portrait of a dedicated scientist and the archetypal story of all medical research, Human Trials is the emotion-laden, roller-coaster trip from the lab bench to the medicine cabinet, in which scientists risk their reputations, venture capitalists their millions, and patients their very lives. A Merloyd Lawrence Book

The Baltimore Case A Trial of Politics Science and Character

Author: Daniel J. Kevles
Publisher: W. W. Norton & Company
ISBN: 0393254860
Format: PDF, Mobi
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"You read with a rising sense of despair and outrage, and you finish it as if awakening from a nightmare only Kafka could have conceived."--Christopher Lehmann-Haupt, New York Times David Baltimore won the Nobel Prize in medicine in 1975. Known as a wunderkind in the field of immunology, he rose quickly through the ranks of the scientific community to become the president of the distinguished Rockefeller University. Less than a year and a half later, Baltimore resigned from his presidency, citing the personal toll of fighting a long battle over an allegedly fraudulent paper he had collaborated on in 1986 while at MIT. From the beginning, the Baltimore case provided a moveable feast for those eager to hold science more accountable to the public that subsidizes its research. Did Baltimore stonewall a legitimate government inquiry? Or was he the victim of witch hunters? The Baltimore Case tells the complete story of this complex affair, reminding us how important the issues of government oversight and scientific integrity have become in a culture in which increasingly complicated technology widens the divide between scientists and society.