A Practical Approach to the Spectrum of Alcoholic Liver Disease An Issue of Clinics in Liver Disease E Book

Author: David Bernstein
Publisher: Elsevier Health Sciences
ISBN: 1455747378
Format: PDF, Mobi
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The Guest Editor has organized this issue to focus on the clinical management of alcoholic liver disease. Authors have written state-of-the-art reviews on the following topics: Prevalence and Natural History of ALD; Alcohol Metabolism; Immunology in ALD; Histological Findings in ALD; Diagnosis and Management of Alcoholic Hepatitis; Management of Alcohol Abuse; Long Term Management of Alcoholic Liver Disease; Infections in ALD; Nutrition in ALD; Alcohol’s Effect on Other Chronic Liver Diseases; Liver Cancer and Alcohol; Evaluation and Selection of Candidates for Liver Transplantation; and ALD and Specific Transplant-Related Issues.

Alcoholic Liver Disease An Issue of Clinics in Liver Disease E Book

Author: Norman L. Sussman
Publisher: Elsevier Health Sciences
ISBN: 0323654525
Format: PDF, Docs
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Alcoholic liver disease has once again entered our collective conscience. A paper in 2012 showed the utility of orthotopic liver transplantation (OLT) in acute alcoholic hepatitis. As expected, this opened the floodgates. Every liver transplant program in the USA is now under pressure to list and transplant patients with alcoholic liver disease (ALD), resulting n a shift in the type of patients to admit and list for OLT. In consultation with Dr. Norman Gitlin, Dr. Norman Sussman and Dr. Michael Lucey have put together a collection of articles on current practices and future trends in the management of alcohol-related diseases. Expert authors from top institutions have contributed articles on the following topcs: Histopathology; Alcohol and the Law; Alcoholic Liver Disease in Children; Alcohol Use Disorder; Pathogenesis of ALD; Acute Alcoholic Hepatitis; Nutrition and Malnutrition in ALD; Alcoholic Cirrhosis; Liver Transplantation for Alcoholic Liver Disease; CNS effects of Alcohol; and Will Studies in NASH Help to Manage AS. Readers will come away with current clinical information to help them to make clinical decisions that will improve patient outcomes.

Alcoholic Liver Disease An Issue of Clinics in Liver Disease

Author: Stanley Cohen
Publisher: Elsevier Health Sciences
ISBN: 0323459749
Format: PDF, ePub
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Alcohol abuse remains a significant problem world-wide. The most commonly affected organ remains the liver with a risk of alcoholic liver disease (ALD) which can range from asymptomatic to alcoholic hepatitis to alcoholic cirrhosis. In 2010, alcohol-attributable cirrhosis was responsible for 0.9% of all global deaths. Given the sheer magnitude of alcohol abuse and alcoholic liver disease, an update on this topic is pertinent and relevant. This issue will focus on a variety of topics including alcoholism, the pathogenesis of ALD, the spectrum of ALD, the pathology of ALD, and the long-term management of patients with ALD. Alcoholic hepatitis is a particular type of ALD with a high mortality. This issue will explore the syndrome of alcoholic hepatitis, its prognostic markers, and the available therapies. Because alcohol intake can influence so many other conditions of the liver (especially hepatitis C), articles in this issue will also explore the impact of alcohol abuse on other liver conditions. In addition, several other topics such as nutritional therapy for ALD, ALD and liver cancer, and ALD and infection risk will be explored. Also, even though it is quite controversial, we will also explore liver transplant as a therapy for alcoholic liver disease including alcoholic hepatitis.

Alcoholic Liver Disease an Issue of Clinics in Liver Disease

Author: Carroll B. Leevy
Publisher: Saunders
ISBN: 9781416027782
Format: PDF, ePub, Docs
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Alcohol is the most frequently used drug worldwide and remains a socially acceptable hepatotoxin. Drinking is the most common cause of liver-related mortality in the United States. Topics covered in this issue include nutrient deficiency in alcoholic liver disease, long term management of lacholic liver disease, and the role of liver transplantation in alcoholic liver disease.

Approach to Consultations for Patients with Liver Disease An Issue of Clinics in Liver Disease E Book

Author: Steven L. Flamm
Publisher: Elsevier Health Sciences
ISBN: 1455744131
Format: PDF, ePub, Mobi
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With very much success in 2009, this topic is being updated again in 2012. Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluatio of Elevated Liver Enzymes and Abnormal Liver Panel; Evaluation of Liver Lesions; Chronic HCV; Evaluation of Hepatic Cholestasis; Chronic HBV; Ascites; Fatty Liver; Pruritus in the patient with chronic cholestatic liver disease; Is the patient a candidate for liver transplantation; Care of the cirrhotic patient; Abnormal liver panel in pregnancy; Surgical clearance for the patient with chronic liver disease; Granulomatous Liver Disease; Drug Induced Liver Disease; and Hepatic Encephalopathy.

Non Alcoholic Fatty Liver Disease An Issue of Clinics in Liver Disease

Author: Paul J. Gaglio
Publisher: Elsevier Health Sciences
ISBN: 0323416977
Format: PDF, ePub, Docs
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Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.

Non Alcoholic Fatty Liver Disease an Issue of Clinics in Liver Disease

Author: Paul J. Gaglio
Publisher: Elsevier
ISBN: 9780323416962
Format: PDF, ePub
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Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.

Drug Hepatotoxicity An Issue of Clinics in Liver Disease

Author: Vinod Rustgi
Publisher: Elsevier Health Sciences
ISBN: 0323496628
Format: PDF, Mobi
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Dr. Rustgi has assembled the leading experts in the management of Heptatitis B to present the current treatment and clinical course for diagnosis and management of the disease. Articles are devoted to: Drug metabolism in the liver; Mechanism of Liver Damage including the RUCAM scale; Drug-induced acute liver failure; Epidemiology and genetic risk factors; Adverse drug reactions: type A (intrinsic or pharmacological) or type B (idiosyncratic); Pathology of injury including phenotypes; The clinical course of drug-induced liver disease; Environmental factors of drug hepatotoxicity; Newer agents in drug hepatotoxicity; Drug hepatotoxicity: herbal products; Drug hepatotoxicity: models including “human on a chip and zebrafish; Acute and chronic liver failure from drugs: impact on the kidney; and Management of acute hepatotoxicity including medical agents and liver support systems. Readers will come away with the cutting edge science behind the latest innovations in the treatment of Hepatitis B.

Liver Transplantation An Issue of Clinics in Liver Disease E Book

Author: Roberto J. Firpi
Publisher: Elsevier Health Sciences
ISBN: 0323528457
Format: PDF
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Cirrhosis from hepatitis C (HCV) is now the most common indication for liver transplant (LT) in the U.S., but between 2004 and 2013, new LT listings for NASH increased by 170%. Unfortunately, fibrosis progression leading to cirrhosis, liver cancer, and liver decompensation continues to occur after transplantation. Once cirrhosis and decompensation are evident, patient survival is poor and repeat LT is considered to improve outcomes. Therefore, the never-ending thirst for new approaches in the management of patients pre- and post-transplant has led to a very promising future in transplantation, thought there is much to learn to achieve better patient outcomes. This issue of Clinics in Liver Disease addresses the core areas to achieve better patient outcomes, with articles devoted to coagulopathy before liver transplant, challenges in renal failure before LT, LT for acute alcoholic hepatitis, LT in the pregnant patient, bariatric surgery and LT,and MELD Scores in prioritization of LT, to name a few. Readers will place a high value on the current state of liver transplantation in this issue.

Consultations in Liver Disease An Issue of Clinics in Liver Disease

Author: Steven L. Flamm
Publisher: Elsevier Health Sciences
ISBN: 0323354610
Format: PDF
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Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.