Alzheimer s Disease

Author: Amy Borenstein
Publisher: Academic Press
ISBN: 0124171540
Format: PDF
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Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest

Global Clinical Trials for Alzheimer s Disease

Author: Tiia Ngandu
Publisher: Elsevier Inc. Chapters
ISBN: 0128070366
Format: PDF, Docs
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Today there are more than 36 million demented persons worldwide. With the aging of populations, the prevalence of dementia and Alzheimer’s disease (AD) is expected to more than triple in the coming 40 years. Besides high age and genetic factors, evidence from observational studies shows that many modifiable vascular and lifestyle-related risk factors at midlife affect the risk of the disease. Control of vascular and metabolic risk factors, healthy diet, and maintenance of AN active lifestyle (physical, mental, and social components) may thus be the key issues on the road to prevent or delay the onset of AD. As the pathologic processes leading to AD may take decades to develop, it is crucial to identify optimal time windows for preventive efforts. Targeting several risk factors simultaneously and long duration of the intervention may be needed for the optimal preventive effect. As many persons are affected, relatively small effects of an integrative intervention on common risk factors may have a huge public health impact. Usage of biomarkers may help in identifying different risk phenotypes and in monitoring effects of the interventions. International collaboration is necessary to initiate future large-scale dementia prevention studies that are needed to formulate evidence-based preventive measures in cognitive decline and dementia.

A Life Course Approach to Healthy Ageing

Author: Yoav Ben-Shlomo
Publisher: Oxford University Press
ISBN: 0199656517
Format: PDF, ePub, Mobi
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This title investigates the lifetime determinants of healthy ageing and their implications for policy and practice, bringing together authorities in ageing research and knowledge transfer from across the world.

Early Intervention in Psychiatry

Author: Peter Byrne
Publisher: John Wiley & Sons
ISBN: 1118387775
Format: PDF, ePub, Docs
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Early intervention (EI) is the single most important advance in mental health care in recent decades, representing a key shift in both theoretical standpoint and service delivery. Early Intervention in Psychiatry clearly describes best practice for extending this approach to all psychiatric disorders. Beginning with the rationale for EI, it informs interventions in people from all age groups across the lifespan, from perinatal to old age. It addresses EI in specific settings, such as primary health care, community health, the general hospital, non-government agencies, and in social movements, and for specific disorders including depression and anxiety, alcohol and substance use, childhood disorders, psychoses, bipolar disorders, eating disorders and borderline personality disorders. Early Intervention in Psychiatry is an essential guide for all psychiatrists, general practitioners, family physicians and public health doctors. It is also a valuable resource for mental health professionals and primary care colleagues, including nurses, social workers, psychologists, occupational therapists, vocational rehabilitation specialists, peer and support workers and for mental health commissioners and policy-makers.

Oxford Textbook of Old Age Psychiatry

Author: Tom Dening
Publisher: OUP Oxford
ISBN: 0191006750
Format: PDF, Kindle
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Broad in scope and with global appeal The Oxford Textbook of Old Age Psychiatry, second edition is the definitive resource on old age psychiatry. It comprehensively provides the latest knowledge on the science and practice of treating later life mental disorders, focusing on the health and social issues that arise around ageing, dementia, co-morbidity, dependency, and the end of life in progressively ageing societies across the world. Published in previous incarnations as the much loved Psychiatry in the Elderly, this core resource for all old age psychiatrists, trainees, and other clinical professionals treating older people's mental health, has been fully revised, updated, and significantly expanded. Twelve months inclusive access to the online version, including the full text (which can be browsed by the contents list, index, or searched), links from references to external sources (via PubMed, ISI, and CrossRef), and the ability to download all figures and illustrations into PowerPoint ensures that it remains the leading text on old age psychiatry in the field. Maintaining the classic combination of comprehensive coverage, clear writing style, and the provision of authoritative and up-to-date information from earlier editions, this highly respected volume covers the underpinning basic science, both the neurobiological and social varieties, clinical practice, and specific disorders, as well as providing information on psychiatric services for older people, and medico-legal and ethical issues that often present hard challenges for those treating older patients. Taking a global approach by highlighting both the common burdens and the differences in management from country to country and with a much expanded cast of contributors providing a truly international perspective, The Oxford Textbook of Old Age Psychiatry, second edition includes information on all the latest improvements and changes in the field. New chapters are included to reflect the development of old age care; covering palliative care, the ethics of caring, and living and dying with dementia. Existing chapters have also been revised and updated throughout and additional information is included on brain stimulation therapies, memory clinics and services, and capacity, which now includes all mental capacity and decision making. Providing extensive coverage and written by experts the field, the second edition of the Oxford Textbook of Old Age Psychiatry is an essential resource; no old age psychiatrist, trainee, or anyone working in the field of mental health care for older people should be without a copy on their bookshelf.

Ethics Law and Aging Review Volume 7

Author: Marshall B. Kapp, JD, MPH, FCLM
Publisher: Springer Publishing Company
ISBN: 9780826115799
Format: PDF
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Health care and human service professionals often experience anxiety about potential adverse legal repercussions for actions taken or not taken in the course of caring for patients or clients. In this volume, professionally distinguished and diverse authors discuss both the real and perceived legal liability context within which health and human service delivery to older persons takes place. The benefits and costs of litigious, legislative, and regulatory interventions on the quality of care and the quality of life for recipients of geriatric services is evaluated. Most important, chapters present suggestions for ways to effectively reduce or manage legal risks and anxieties while improving patient care. This volume fills a gap in the literature by providing careful and accurate analysis of legal issues rarely translated into practical and useful advice for health care and human service professionals.

Capturing Social and Behavioral Domains in Electronic Health Records

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309301130
Format: PDF, ePub, Docs
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Substantial empirical evidence of the contribution of social and behavioral factors to functional status and the onset and progression of disease has accumulated over the past few decades. Electronic health records (EHRs) provide crucial information to providers treating individual patients, to health systems, including public health officials, about the health of populations, and to researchers about the determinants of health and the effectiveness of treatment. Inclusion of social and behavioral health domains in EHRs is vital to all three uses. The Health Information Technology for Economic and Clinical Health Act and the Patient Protection and Affordable Care Act place new importance on the widespread adoption and meaningful use of EHRs. "Meaningful use" in a health information technology context refers to the use of EHRs and related technology within a health care organization to achieve specified objectives. Achieving meaningful use also helps determine whether an organization can receive payments from the Medicare EHR Incentive Program or the Medicaid EHR Incentive Program. Capturing Social and Behavioral Domains in Electronic Health Records is the first phase of a two-phase study to identify domains and measures that capture the social determinants of health to inform the development of recommendations for meaningful use of EHRs. This report identifies specific domains to be considered by the Office of the National Coordinator, specifies criteria that should be used in deciding which domains should be included, identifies core social and behavioral domains to be included in all EHRs, and identifies any domains that should be included for specific populations or settings defined by age, socioeconomic status, race/ethnicity, disease, or other characteristics.

Chronic Medical Disease and Cognitive Aging

Author: Kristine Yaffe
Publisher: Oxford University Press
ISBN: 0199396221
Format: PDF
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Chronic Medical Disease and Cognitive Aging: Toward a Healthy Body and Brain explores the important and often overlooked connection between how chronic medical diseases of the body can affect cognitive function and brain health. As population demographics shift to that of an aging population it has become more important to understand and improve cognitive function in late life. Chronic medical diseases often increase the risk of cognitive impairment, and those with cognitive impairment may be less able to effectively manage their medical conditions, suggesting a reciprocal relationship may exist where medical disease impacts cognition that in turn may exacerbate physical health. Chronic Medical Disease and Cognitive Aging discusses current research on the association between a variety of chronic medical diseases and cognition and, where appropriate, promising interventions or accepted treatment strategies. While a cure for many diseases continues to be elusive, insights garnered from the interplay between diseases of the body and mind may help point the way to novel therapeutic strategies to improve cognitive function in late life.

Life course perspectives on adulthood and old age

Author: Marsha Mailick Seltzer
Publisher: Amer Assn on Intellectual&Devel
Format: PDF, ePub
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This volume takes current stock of our current state of knowledge about aging & mental retardation. Its contributors articulate the implications of our knowledge for service delivery issues & policy development & chart directions for future research. Leading researchers present the results of their work, many of whom participated in the Boston Roundtable on Research & Applications in Aging & Developmental Disabilities, held in Boston in November 1990. The impetus for this publication is linked to the effectiveness of the Roundtable meeting held in conjunction with the Annual Meeting of the Gerontological Society of America, in exposing the dynamic range of research currently being conducted & reported. This volume is composed of four sections. The first section addresses the family context of care for adults & elders with mental retardation. The second section examines individual development of people with mental retardation during adulthood & old age. The third section focuses on the provision of services to older people with mental retardation & their families. The final section addresses methodological challenges facing researchers who study aging in people with mental retardation & their families, & can daunt or inspire researchers who seek to unravel the mysteries of human development in the later decades of life.