Arenaviruses I

Author: M.B.A. Oldstone
Publisher: Springer Science & Business Media
ISBN: 3642560296
Format: PDF, Docs
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Since the subject of arenaviruses was visited by Current Topics in Microbiology and Immunology 14 years ago, enormous advances have been made in this area. The receptor for several arenaviruses, alpha-dystroglycan, was identified, the replication strategy of these viruses was decoded, and application of a reverse genetics system for studying viral gene function and viral biology is well underway. In addition to reviewing these advances, Volume I includes discussion of arenaviral molecular phylogeny, reservoirs in rodents and clinical diseases caused by both new world and old world arenaviruses.

Viral Hemorrhagic Fevers

Author: Sunit K. Singh
Publisher: CRC Press
ISBN: 1439884315
Format: PDF, ePub, Mobi
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Viral hemorrhagic fevers have captured the imagination of the public and made their way into popular books and movies by virtue of their extreme virulence and mysterious origins. Since 2001, concerns have grown about the potential use of many hemorrhagic fever viruses as biological weapons. This has led to a resurgence in research to develop improved diagnostics, vaccines, and therapeutics—both for biodefense purposes and to treat naturally exposed persons. Written by international experts, Viral Hemorrhagic Fevers represents a major contribution to the virological literature and updates the state of knowledge of these dangerous illnesses. Topics include: A historical perspective and information on pathogenesis and immune responses Animal models, which are critical to the development of vaccines and therapeutics The roles of high-containment facilities and specially trained scientists in research Prevention and control, including diagnostics and vaccine development Old World Lassa and Lujo viruses and the New World Junin and Machupo viruses Guanarito viruses and their cellular receptors Bunyaviruses, including Rift Valley Fever, Crimean– Congo hemorrhagic fever, and hantaviruses that cause hemorrhagic fever with renal syndrome The Ebola and Marburg filoviruses Flaviviruses, including dengue fever, yellow fever, Kyanasur Forest, Alkhurma, and Omsk hemorrhagic fever viruses and other flaviviruses with hemorrhagic potential Virologists, clinicians, biomedical researchers, microbiologists, and others needing a rapid overview of the nature of these illnesses will find this book an essential resource on clinical and basic science aspects of many viral hemorrhagic fevers. The book will also provide researchers with a springboard to further inquiry in combating what has become a major global threat.

Manual of Security Sensitive Microbes and Toxins

Author: Dongyou Liu
Publisher: CRC Press
ISBN: 1466553987
Format: PDF, Kindle
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Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern. The ultimate goal is to increase our awareness of these agents and enhance our preparedness against any future bio-emergencies. The book begins with an introduction containing a brief overview of the historical aspects of security sensitive microbes and toxins. This is followed by a concise summary of the current status in relation to the regulation of security sensitive microbes and toxins and a discussion of future development trends. The book is divided into seven parts: Microbes and Toxins Affecting Humans and Animals: Viruses Microbes and Toxins Affecting Human and Animals: Bacteria Microbes and Toxins Affecting Human and Animals: Fungus and Parasite Microbes and Toxins Affecting Human and Animals: Toxins Microbes Affecting Animals: Viruses Microbes Affecting Animals: Bacteria Microbes Affecting Plants Written by experts in the relevant areas of research, the chapters are authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.

Zoonoses

Author: Stephen R. Palmer
Publisher: Oxford University Press, USA
ISBN:
Format: PDF, ePub, Docs
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Zoonoses are diseases naturally transmissible between vertebrate animals and man including those transmitted by direct contact with infected animals or carcases, by food or water contamination, and by inhalation of infected dust. They are increasingly important in public health issues. Thismultidisciplinary book is written by international specialists in human and veterinary medicine. Divided into three sections along the lines of bacteriology, parasitology and virology, this book comprehensively covers all zoonoses. Each of the seventy chapters covers the history of the disease, thescientific basis for the control of zoonoses, the microbiology of the causative agent, pathogenesis, clinical features, symptoms and signs, diagnosis, treatment and prognosis. The epidemiology of each disease is described alongside the strategies for prevention and control.

Principles and Practice of Clinical Virology

Author: Arie J. Zuckerman
Publisher: Wiley
ISBN: 9780471973409
Format: PDF, Docs
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Virology is that branch of microbiology concerned with viruses and diseases. These groups of minute infectious agents are, with certain exceptions (e.g., poxviruses) lack an independent metabolism and replicate only within living host cells. Like living organisms, they reproduce with genetic continuity and also mutate. Normally classified into three subgroups on the basis of host specificity (bacterial viruses, animal viruses, and plant viruses), they are also classified by origin, mode of transmission, symptoms produced, and where first located.