Atherosclerosis

Author: Hong Wang
Publisher: John Wiley & Sons
ISBN: 1118285913
Format: PDF, ePub, Docs
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Comprehensive and in-depth in its coverage, Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy reviews the recent progress in atherosclerosis research and offers cutting edge perspectives from experts in the field. Written by an international team of authors including leading physician-scientists, research experts and physicians, chapters are divided into four major sections, covering risk factors, cellular and molecular mechanisms, biochemical mechanisms and novel and future therapeutics. Atherosclerosis: Cellular, Molecular & Biochemical Mechanism and Novel Therapy analyses recent progress from both conceptual and technological perspectives, suggesting new directions for atherosclerosis research and treatment for a growing population of researchers and clinicians in cardiovascular and related fields.

High Risk Atherosclerotic Plaques

Author: Levon Michael Khachigian
Publisher: CRC Press
ISBN: 1420037889
Format: PDF, Docs
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Vulnerable plaque development is the result of a complex series of molecular and cellular events involving inflammation, apoptosis, rupture, and thrombosis. A detailed understanding of the mechanisms underlying the development of high-risk plaques, along with the ability to visualize and diagnose these vulnerable lesions, will lead to the effective management of acute coronary syndromes. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy brings together timely, in-depth reviews by renowned international cardiologists and scientists. Chapters cover the definition, structure, and cellular and molecular mechanisms of high risk plaque development, as well as animal models of vulnerable plaque, plaque imaging, and current and future therapies. Medical experts discuss intravascular ultrasound, optimal coherence tomography, magnetic resonance imaging, and coronary thermography. The final chapter reviews both current and future local and systematic strategies for the therapeutic management of vulnerable plaque. Exploring all aspects of this primary cause of acute coronary syndromes, this informative book updates our knowledge on the detection and treatment of vulnerable plaques. It is a valuable resource that can greatly advance the progress in treatment and prevention.

Molecular Mechanisms of Atherosclerosis

Author: Joseph Loscalzo
Publisher: CRC Press
ISBN: 020300583X
Format: PDF, Kindle
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Atherosclerosis is the most common cardiovascular disorder in western societies and is rapidly becoming similarly prevalent in the underdeveloped world. Written by notable authorities and providing text rich in illustrative figures, Molecular Mechanisms in Atherosclerosis addresses the fundamental mechanisms underlying atherothrombosis and delineates current views of the molecular and cellular basis of the process. The editor approaches the issue from a mechanistic perspective, and does so in the context of contemporary knowledge of molecular and cellular pathobiology. The book provides an epidemiological overview of atherosclerotic vascular disease, followed by a review of the genetics and genetic epidemiology. It focuses on the four fundamental mechanisms common to all risk factors for atherosclerosis: inflammation, oxidative stress, thrombosis, and endothelial dysfunction and the mechanisms under lying for common risk factors for atherogenesis: dyslipidaemias, diabetes mellitus, hypertension, and smoking. The book then discusses the recently proposed risk factors hyperhomocysteinemia and infection and rational molecular therapies to prevent and combat established atherothrombotic disease. Taken together, these chapters offer a broad review of the molecular and cellular mechanisms of atherothrombogenesis. The topics covered and the order of presentation were carefully chosen to clarify the complexity of the disease process. Armed with the information contained in this text, you can confidently explore cutting-edge research with insight and foresight regarding their implications for prevention and treatment.

Coronary Care Manual

Author: Peter L. Thompson
Publisher: Elsevier Health Sciences
ISBN: 0729579271
Format: PDF, ePub, Mobi
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A comprehensive coronary care textbook for medical, nursing and paramedic staff The Coronary Care Manual, 2nd Edition is a practical medical manual designed to assist with management of the acute coronary patient. This respected medical resource is written by a group of coronary experts, both Australian and international. Its aim is to strike a balance between a large and rapidly-changing evidence base and practical application in the Coronary Care Unit, Intensive Care Unit, Emergency Department and the ambulance. The second edition of this important health textbook covers an extensive range of coronary care medicine, providing a handy companion for a night ‘on call’. Chapter topics in the Coronary Care Manual, 2nd Edition include pathophysiology, drug and non-drug therapies and postcoronary management, with chapters organised into subsections. Completely redesigned with fresh, new artwork, this new edition of the Coronary Care Manual is organised to suit academics and medical practitioners alike. • covers a broad range of coronary care medicine • provides specific advice on the management of common clinical problems • eliminates the need to refer to a larger reference book • features a consistent style and focus, with standardised artwork for figures • is now also available as an eBook! A code inside the Coronary Care Manual enables a full text download, allowing you to browse and search electronically, make notes and bookmarks in the electronic files and highlight material

Clinical Lipidology

Author: Christie M. Ballantyne
Publisher: Elsevier Health Sciences
ISBN: 1416054693
Format: PDF, Kindle
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The author, one of the lipid experts in the world, together with a cast of contributors, provides all of the scientific and clinical information needed to manage every aspect of dyslipidemia. From basic science to pathogenesis of atherothrombotic disease to risk assessment and the latest therapy options, this new title in the Braunwald's Heart Disease family offers up-to-date coverage and guidance on lipidology in a straightforward, accessible, and user-friendly style. Contains extensive clinically relevant information covering risk assessment, therapy, special patient populations, and experimental therapies, including targeting HDL to help you effectively manage any challenges you face. Uses treatment algorithms for easy access to key content. Presents current practice guidelines that assist in the decision-making process.

Cardiology Essentials in Clinical Practice

Author: Gabriel A. Adelmann
Publisher: Springer Science & Business Media
ISBN: 9781849963053
Format: PDF, Mobi
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This book addresses the entire cardiological pathology, and accompanies the reader through each significant condition, from incidence and severity, to mechanisms, clinical and lab diagnosis, and up to treatment and prognosis.The presentation is enhanced by the use of numerous tables and figures, to better illustrate the similarities and differences between the discussed entities. The chapters have an uniform structure fostering a methodical approach to heart disease. The level is intermediate, with an accent on clinical practice. At the same time, an excellent tool for preparing for exams, as i) disease mechanisms are systematically discussed; ii) guidelines are explained and summarized; iii) novel resarch directions are explained. The book provides conciseness, completeness, and updatedness, while offers: for residents, familiarization with the discipline of cardiology; for cardiology fellows, the book will be a friendly companion for practice and Boards study; for primary care physicians, the book represents an update to their knowledge; while for clinical cardiologists, the book represents a companion reference.

Cardiorenal Syndrome

Author: Adel E. Berbari
Publisher: Springer Science & Business Media
ISBN: 9788847014633
Format: PDF, Docs
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Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease. Several pathophysiologic mechanisms have been postulated to explain the relationship between renal dysfunction and cardiovascular disease. Recent studies indicate an integrated response of the vascular smooth muscles and glomerular mesangial cells to traditional and uremia related cardiovascular risk factors. Traditional risk factors can incite renal impairment and cardiac damage. As renal function deteriorates, uremia-related risk factors play an increasing role both in reduction in glomerular filtration rate and cardiovascular damage. Several uremia related factors such as uncontrolled hypertension, disturbed glucose insulin metabolism, microalbuminuria, phosphate retention, secondary hyperparathyroidism, myocardial and vascular calcification, hypertensive-uremic cardiomyopathy, inflammation, oxidant injury, and neurohormonal dysregulation have been implicated in the pathogenesis of the cardiorenal syndrome. Recent data suggest that management of the cardiorenal syndrome requires aggressive control of traditional risk factors as well novel approaches to prevent or reverse uremia –related processes. This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology, pathophysiologic mechanisms, and therapeutic approaches.

Netter s Cardiology Book and Online Access at www NetterReference com

Author: George Stouffer
Publisher: Elsevier Health Sciences
ISBN: 1437736505
Format: PDF, ePub, Docs
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Netter’s Cardiology, 2nd Edition, by Marschall S. Runge, Cam Patterson, and George Stouffer, uses visually rich Netter artwork to efficiently provide you with a concise overview of cardiovascular anatomy, pathophysiology, diagnosis, and management. You'll rapidly access complete introductions to common issues in cardiology, including annotated references of the most important articles, guidelines, and available evidence. Netter - it's how you know. Efficiently review key details of anatomy, pathophysiology, and clinical presentation with detailed, crystal-clear artwork by Frank H. Netter, MD and other illustrators working in the Netter tradition. Apply dependable clinical advice from Marschall S. Runge, MD, PhD, Cam Patterson, MD and George Stouffer, MD and utilize diagnostic and therapeutic algorithms and clinical pathways developed by the many world-renowned chapter contributors. Utilize annotated references to the most important resources and evidence-based studies. Benefit from expanded coverage of cardiovascular imaging including echocardiography, stress testing and nuclear imaging, and CT and MRI.

Cardiology E Book

Author: Michael H. Crawford
Publisher: Elsevier Health Sciences
ISBN: 0723436444
Format: PDF, ePub
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With your heavy case load, you can't afford to waste time searching for answers. Cardiology, 3rd Edition, by Drs. Crawford, DiMarco, and Paulus, offers you just the practical, problem-based guidance you need to quickly overcome any clinical challenge. 8 color-coded sections cover the 8 major clinical syndromes of cardiovascular disease—each section a virtual "mini textbook" on its topic! 40 new chapters keep you up to date with the latest advances in the field, while more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs capture clinical manifestations as they present in practice. It’s current, actionable information that you can put to work immediately for your patients! Offers a problem-based approach that integrates basic science, diagnostic investigations, and therapeutic management in one place for each cardiovascular disease so you can quickly find all of the actionable knowledge you need without flipping from one section to another. Features introductory bulleted highlights in each chapter that present the most pertinent information at a glance. Presents abundant algorithms to expedite clinical decision making. Includes more than 2,000 lavish, high-quality illustrations, color photographs, tables, and ECGs that capture clinical manifestations as they present in practice, and promote readability and retention. Includes 40 new chapters including Inherited Arrhythmia Syndromes, Implantable Cardioverter-Defibrillators and Cardiac Resynchronization Therapy in CHD, Management of the Cyanotic Patient with CHD, Special Problems for the Cardiology Consultant Dealing with Bariatric/Gastric Bypass — and many more — that equip you with all of the latest knowledge. Presents "Special Problem" sections—many new to this edition—that provide practical advice on problems that can be difficult to treat.