Bioinformatics Challenges at the Interface of Biology and Computer Science

Author: Teresa K. Attwood
Publisher: John Wiley & Sons
ISBN: 1119243440
Format: PDF, Mobi
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This innovative book provides a completely fresh exploration of bioinformatics, investigating its complex interrelationship with biology and computer science. It approaches bioinformatics from a unique perspective, highlighting interdisciplinary gaps that often trap the unwary. The book considers how the need for biological databases drove the evolution of bioinformatics; it reviews bioinformatics basics (including database formats, data-types and current analysis methods), and examines key topics in computer science (including data-structures, identifiers and algorithms), reflecting on their use and abuse in bioinformatics. Bringing these disciplines together, this book is an essential read for those who wish to better understand the challenges for bioinformatics at the interface of biology and computer science, and how to bridge the gaps. It will be an invaluable resource for advanced undergraduate and postgraduate students, and for lecturers, researchers and professionals with an interest in this fascinating, fast-moving discipline and the knotty problems that surround it.

Biomedical Texture Analysis

Author: Adrien Depeursinge
Publisher: Academic Press
ISBN: 0128123214
Format: PDF
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Biomedical Texture Analysis: Fundamentals, Applications, Tools and Challenges describes the fundamentals and applications of biomedical texture analysis (BTA) for precision medicine. It defines what biomedical textures (BTs) are and why they require specific image analysis design approaches when compared to more classical computer vision applications. The fundamental properties of BTs are given to highlight key aspects of texture operator design, providing a foundation for biomedical engineers to build the next generation of biomedical texture operators. Examples of novel texture operators are described and their ability to characterize BTs are demonstrated in a variety of applications in radiology and digital histopathology. Recent open-source software frameworks which enable the extraction, exploration and analysis of 2D and 3D texture-based imaging biomarkers are also presented. This book provides a thorough background on texture analysis for graduate students, and biomedical engineers from both industry and academia who have basic image processing knowledge. Medical doctors and biologists with no background in image processing will also find available methods and software tools for analyzing textures in medical images. •Defines biomedical texture precisely and describe how it is different from general texture information considered in computer vision •Define the general problem to translate 2D and 3D texture patterns from biomedical images to visually and biologically relevant measurements •Describes, using intuitive concepts, how the most popular biomedical texture analysis approaches (e.g., gray-level matrices, fractals, wavelets, deep convolutional neural networks) work, what they have in common, and how they are different •Identifies the strengths, weaknesses, and current challenges of existing methods including both handcrafted and learned representations, as well as deep learning. The goal is to establish foundations for building the next generation of biomedical texture operators •Showcases applications where biomedical texture analysis has succeeded and failed •Provides details on existing, freely available texture analysis software, helping experts in medicine or biology develop and test precise research hypothesis

Developing Bioinformatics Computer Skills

Author: Cynthia Gibas
Publisher: "O'Reilly Media, Inc."
ISBN: 9781565926646
Format: PDF, ePub
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Offers a structured approach to biological data and the computer tools needed to analyze it, covering UNIX, databases, computation, Perl, data mining, data visualization, and tailoring software to suit specific research needs.

Bioinformatics Computing

Author: Bryan P. Bergeron
Publisher: Prentice Hall Professional
ISBN: 9780131008250
Format: PDF, Kindle
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Comprehensive and concise, this handbook has chapters on computing visualization, large database designs, advanced pattern matching and other key bioinformatics techniques. It is a practical guide to computing in the growing field of Bioinformatics--the study of how information is represented and transmitted in biological systems, starting at the molecular level.

Algorithms on Strings Trees and Sequences

Author: Dan Gusfield
Publisher: Cambridge University Press
ISBN: 1139811002
Format: PDF, Kindle
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String algorithms are a traditional area of study in computer science. In recent years their importance has grown dramatically with the huge increase of electronically stored text and of molecular sequence data (DNA or protein sequences) produced by various genome projects. This 1997 book is a general text on computer algorithms for string processing. In addition to pure computer science, the book contains extensive discussions on biological problems that are cast as string problems, and on methods developed to solve them. It emphasises the fundamental ideas and techniques central to today's applications. New approaches to this complex material simplify methods that up to now have been for the specialist alone. With over 400 exercises to reinforce the material and develop additional topics, the book is suitable as a text for graduate or advanced undergraduate students in computer science, computational biology, or bio-informatics. Its discussion of current algorithms and techniques also makes it a reference for professionals.

Essential Bioinformatics

Author: Jin Xiong
Publisher: Cambridge University Press
ISBN: 113945062X
Format: PDF
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Essential Bioinformatics is a concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods. This balanced yet easily accessible text will be invaluable to students who do not have sophisticated computational backgrounds. Technical details of computational algorithms are explained with a minimum use of mathematical formulae; graphical illustrations are used in their place to aid understanding. The effective synthesis of existing literature as well as in-depth and up-to-date coverage of all key topics in bioinformatics make this an ideal textbook for all bioinformatics courses taken by life science students and for researchers wishing to develop their knowledge of bioinformatics to facilitate their own research.

Search Computing

Author: Stefano Ceri
Publisher: Springer Science & Business Media
ISBN: 3642123090
Format: PDF, Docs
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Containing detailed papers on search computing, this book includes some visionary contributions on the latest trends and explores the background and related technologies. The papers are written by leading scientists and contain the latest results in the field.

Learning Computer Architecture with Raspberry Pi

Author: Eben Upton
Publisher: John Wiley & Sons
ISBN: 1119183936
Format: PDF, ePub
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"In the 1980s, the tech revolution was kickstarted by a flood of relatively inexpensive, highly programmable computers like the Commodore. Now, a second revolution in computing is beginning with the Raspberry Pi. Learning Computer Architecture with the Raspberry Pi is the premier guide to understanding the components of the most exciting tech product available. Thanks to this book, every Raspberry Pi owner can understand how the computer works and how to access all of its hardware and software capabilities. Now, students, hackers, and casual users alike can discover how computers work with Learning Computer Architecture with the Raspberry Pi. This book explains what each and every hardware component does, how they relate to one another, and how they correspond to the components of other computing systems. You'll also learn how programming works and how the operating system relates to the Raspberry Pi's physical components. The Raspberry Pi was created to bring forth a new generation of computer scientists, developers, and architects who understand the inner workings of the computers that have become essential to our daily lives. Learning Computer Architecture with the Raspberry Pi is your gateway to the world of computer system design."--Amazon.com.

Mathematics of Bioinformatics

Author: Matthew He
Publisher: John Wiley & Sons
ISBN: 9781118099520
Format: PDF, ePub
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Mathematics of Bioinformatics: Theory, Methods, and Applications provides a comprehensive format for connecting and integrating information derived from mathematical methods and applying it to the understanding of biological sequences, structures, and networks. Each chapter is divided into a number of sections based on the bioinformatics topics and related mathematical theory and methods. Each topic of the section is comprised of the following three parts: an introduction to the biological problems in bioinformatics; a presentation of relevant topics of mathematical theory and methods to the bioinformatics problems introduced in the first part; an integrative overview that draws the connections and interfaces between bioinformatics problems/issues and mathematical theory/methods/applications.

CMPTR

Author: Katherine T. Pinard
Publisher: Cengage Learning
ISBN: 1337000566
Format: PDF, ePub, Mobi
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4LTR Press solutions give students the option to choose the format that best suits their learning preferences. This option is perfect for those students who focus on the textbook as their main course resource. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.