Bioprocessing Piping and Equipment Design

Author: William M. Huitt
Publisher: John Wiley & Sons
ISBN: 1119284236
Format: PDF, Mobi
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The only comprehensive and authoritative reference guide to the ASME Bioprocessing Piping and Equipment (BPE) standard This is a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explains what lies behind many of the requirements and recommendations within that industry standard. Following an introductory narrative to the Standard's early history, industry related codes and standards are explained; the design and engineering aspects cover construction materials, both metallic and nonmetallic; then components, fabrication, assembly and installation of piping systems are explored. Examination, Inspection and Testing then precede the ASME BPE certification process, concluding with a discussion on system design. The author draws on many years' experience and insights from first-hand involvement in the field of industrial piping design, engineering, construction, and management, which includes the bioprocessing industry. The reader will learn why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. This easy to understand and navigate guide will assist engineers (design, piping, chemical, etc.) who need to understand the basis for much of the Standard’s content, as do the contractors and inspectors who have to meet and validate compliance with the BPE Standard. Cover image courtesy of Cotter Brothers Corp., Danvers, MA, USA

Primer on Engineering Standards

Author: Maan H. Jawad
Publisher: John Wiley & Sons
ISBN: 1119466156
Format: PDF, ePub
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A Clear, Comprehensive Introduction to Standards in the Engineering Professions Standards supplement the design process by guiding the designer toward consistency, safety, and reliability. As daily life involves increasingly complex and sophisticated instruments, standards become indispensable engineering tools to ensure user safety and product quality. Primer on Engineering Standards: Expanded Textbook Edition delves into standards creation and compliance to provide students and engineers with a comprehensive reference. The different types of standards are dissected and discussed in terms of development, value, impact, interpretation, and compliance, and options are provided for situations where conformance is not possible. The process of standards creation is emphasized in terms of essential characteristics and common pitfalls to avoid, with detailed guidance on how, where, and with whom one may get involved in official development. Organized for both quick reference and textbook study, this new Expanded Textbook Edition provides a quick, clear understanding of critical concepts, ramifications, and implications as it: Introduces the concepts, history, and classification of standards, rules, and regulations Discusses the federal, state, and local government’s role in standards development and enforcement Distinguishes voluntary consensus standards, limited consensus standards, and jurisdictional versus non-jurisdictional government standards Covers the need for and process of exemptions to existing standards Examines the characteristics of a good standard, and discusses opportunities for involvement in development Includes case studies to demonstrate standards applications, and extensive appendices to direct further inquiry The successful design, fabrication, and operation of any product relies on foundational understanding of pertinent standards; indeed, standards and guidelines form a central pillar of the engineering profession. This helpful resource goes beyond a list of rules to help students and practitioners gain a better understanding of the creation, import, and use of standards.

Stress in ASME Pressure Vessels Boilers and Nuclear Components

Author: Maan H. Jawad
Publisher: John Wiley & Sons
ISBN: 1119259266
Format: PDF, ePub
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An illustrative guide to the analysis needed to achieve a safe design in ASME Pressure Vessels, Boilers, and Nuclear Components Stress in ASME Pressure Vessels, Boilers, and Nuclear Components offers a revised and updatededition of the text, Design of Plate and Shell Structures. This important resource offers engineers and students a text that covers the complexities involved in stress loads and design of plates and shell components in compliance with pressure vessel, boiler, and nuclear standards. The author covers the basic theories and includes a wealth of illustrative examples for the design of components that address the internal and external loads as well as other loads such as wind and dead loads. The text keeps the various derivations relatively simple and the resulting equations are revised to a level so that they can be applied directly to real-world design problems. The many examples clearly show the level of analysis needed to achieve a safe design based on a given required degree of accuracy. Written to be both authoritative and accessible, this important updated book: Offers an increased focus on mechanical engineering and contains more specific and practical code-related guidelines Includes problems and solutions for course and professional training use Examines the basic aspects of relevant theories and gives examples for the design of components Contains various derivations that are kept relatively simple so that they can be applied directly to design problems Written for professional mechanical engineers and students, this text offers a resource to the theories and applications that are needed to achieve an understanding of stress loads and design of plates and shell components in compliance with pressure vessel, boiler, and nuclear standards.

How to Sell Technical Equipment and Services

Author: James R. Hutton
Publisher: PennWell Books
ISBN: 1593700660
Format: PDF, ePub, Mobi
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In this new book, author James R. Hutton shares his decades of experience in the petroleum industry to help readers master the challenge of industrial sales. In How to Sell Technical Services and Equipment, Hutton covers the many aspects involved in B2B sales, with product knowledge being the key to success. Hutton breaks down the process into separate chapters covering more than 60 different topics ranging from identifying the decision makers and gathering intelligence, to handling unpleasant customers and introducing new products. Sales professionals, sales manager, and senior executives in all industries will find the information found in this book to be invaluable. Key Features: • Learn how to respond to tough situations • Learn how to best manage time • Learn how to close the sale • Learn how to impress customers • Learn how to prospect for new business • Learn how to strike responsive chords • Learn how to send out the right signals so the right signals come back

Good Design Practices for GMP Pharmaceutical Facilities

Author: Terry Jacobs
Publisher: Taylor & Francis US
ISBN: 0849398533
Format: PDF, Kindle
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A convenient single-source reference for anyone involved in the planning, construction, validation, and maintenance of modern pharmaceutical facilities, this guide assists project managers as they develop, diagram, and implement pharmaceutical production facility projects-demonstrating how advances in technology and external regulation can impact the production and efficacy of a pharmaceutical facility and the products it produces.

Fundamentals of Mechanical Vibrations

Author: Liang-Wu Cai
Publisher: John Wiley & Sons
ISBN: 1119050227
Format: PDF, ePub
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This introductory book covers the most fundamental aspects of linear vibration analysis for mechanical engineering students and engineers. Consisting of five major topics, each has its own chapter and is aligned with five major objectives of the book. It starts from a concise, rigorous and yet accessible introduction to Lagrangian dynamics as a tool for obtaining the governing equation(s) for a system, the starting point of vibration analysis. The second topic introduces mathematical tools for vibration analyses for single degree-of-freedom systems. In the process, every example includes a section Exploring the Solution with MATLAB. This is intended to develop student's affinity to symbolic calculations, and to encourage curiosity-driven explorations. The third topic introduces the lumped-parameter modeling to convert simple engineering structures into models of equivalent masses and springs. The fourth topic introduces mathematical tools for general multiple degrees of freedom systems, with many examples suitable for hand calculation, and a few computer-aided examples that bridges the lumped-parameter models and continuous systems. The last topic introduces the finite element method as a jumping point for students to understand the theory and the use of commercial software for vibration analysis of real-world structures.

Leachables and Extractables Handbook

Author: Douglas J. Ball
Publisher: John Wiley & Sons
ISBN: 0470173653
Format: PDF, ePub, Mobi
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"Because leachables are non-drug-related impurities, there are increased concerns regarding the risks of inhaling them on a daily basis. This book describes the development and application of safety thresholds for Orally Inhaled and Nasal Drug Products (OINDP). It discusses best practices for evaluation and management of leachables and extractables throughout the pharma product lifecycle by providing practical knowledge about how and why safety thresholds were developed. This book also illustrates how to apply these concepts and principles to products beyond OINDP, and includes an appendix of experimental protocols for laboratory analysis"--Provided by publisher.

A Heat Transfer Textbook

Author: John H Lienhard
Publisher: Courier Corporation
ISBN: 0486318370
Format: PDF, Kindle
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This introduction to heat transfer offers advanced undergraduate and graduate engineering students a solid foundation in the subjects of conduction, convection, radiation, and phase-change, in addition to the related topic of mass transfer. A staple of engineering courses around the world for more than three decades, it has been revised and updated regularly by the authors, a pair of recognized experts in the field. The text addresses the implications, limitations, and meanings of many aspects of heat transfer, connecting the subject to its real-world applications and developing students' insight into related phenomena. Three introductory chapters form a minicourse in heat transfer, covering all of the subjects discussed in detail in subsequent chapters. This unique and effective feature introduces heat exchangers early in the development, rather than at the end. The authors also present a novel and simplified method for dimensional analysis, and they capitalize on the similarity of natural convection and film condensation to develop these two topics in a parallel manner. Worked examples and end-of-chapter exercises appear throughout the book, along with well-drawn, illuminating figures.

RF Superconductivity

Author: Hasan Padamsee
Publisher: John Wiley & Sons
ISBN: 3527627189
Format: PDF, ePub, Docs
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This is the second book to RF Superconducting, written by one of the leading experts. The book provides fast and up-to-date access to the latest advances in the key technology for future accelerators. Experts as well as newcomers to the field will benefit from the discussion of progress in the basic science, technology as well as recent and forthcoming applications. Researchers in accelerator physics will also find much that is relevant to their discipline.

Fundamentals of Modern Bioprocessing

Author: Sarfaraz K. Niazi
Publisher: CRC Press
ISBN: 1466585749
Format: PDF, ePub
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Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.