Biosurfaces

Author: Kantesh Balani
Publisher: John Wiley & Sons
ISBN: 1118950631
Format: PDF
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Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies

Biosurfaces

Author: Kantesh Balani
Publisher: Wiley-American Ceramic Society
ISBN: 9781118299975
Format: PDF, ePub
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Ideal as a graduate textbook, this title is aimed at helping design effective biomaterials, taking into account the complex interactions that occur at the interface when a synthetic material is inserted into a living system. Surface reactivity, biochemistry, substrates, cleaning, preparation, and coatings are presented, with numerous case studies and applications throughout. Highlights include: Starts with concepts and works up to real-life applications such as implantable devices, medical devices, prosthetics, and drug delivery technology Addresses surface reactivity, requirements for surface coating, cleaning and preparation techniques, and characterization Discusses the biological response to coatings Addresses biomaterial-tissue interaction Incorporates nanomechanical properties and processing strategies

Biomaterials from Nature for Advanced Devices and Therapies

Author: Nuno M. Neves
Publisher: John Wiley & Sons
ISBN: 111917807X
Format: PDF
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In-depth information on natural biomaterials and their applications for translational medicine! Undiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world A must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work Link to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used

Medical Coatings and Deposition Technologies

Author: David Glocker
Publisher: John Wiley & Sons
ISBN: 1119308674
Format: PDF, Mobi
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Medical Coatings and Deposition Technologies is an important new addition to the libraries of medical device designers and manufacturers. Coatings enable the properties of the surface of a device to be controlled independently from the underlying bulk properties; they are often critical to the performance of the device and their use is rapidly growing. This book provides an introduction to many of the most important types of coatings used on modern medical devices as well as descriptions of the techniques by which they are applied and methods for testing their efficacy. Developers of new medical devices and those responsible for producing them will find it an important reference when deciding if a particular functionality can be provided by a coating and what limitations may apply in a given application. Written as a practical guide and containing many specific coating examples and a large number of references for further reading, the book will also be useful to students in materials science & engineering with an interest in medical devices. Chapters on antimicrobial coatings as well as coatings for biocompatibility, drug delivery, radiopacity and hardness are supported by chapters describing key liquid coating processes, plasma-based processes and chemical vapor deposition. Many types of coatings can be applied by more than one technique and the reader will learn the tradeoffs given the relevant design, manufacturing and economic constraints. The chapter on regulatory considerations provides important perspectives regarding the marketing of these coatings and medical devices.

Advanced Surfaces for Stem Cell Research

Author: Ashutosh Tiwari
Publisher: John Wiley & Sons
ISBN: 1119242827
Format: PDF
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The book outlines first the importance of Extra Cellular Matrix (ECM), which is a natural surface for most of cells. In the following chapters the influence of biological, chemical, mechanical, and physical properties of surfaces in micro and nano-scale on stem cell behavior are discussed including the mechanotransduction. Biomimetic and bioinspired approaches are highlighted for developing microenvironment of several tissues, and surface engineering applications are discussed in tissue engineering, regenerative medicine and different type of biomaterials in various chapters of the book. This book brings together innovative methodologies and strategies adopted in the research and development of Advanced Surfaces in Stem Cell Research. Well-known worldwide researchers deliberate subjects including: Extracellular matrix proteins for stem cell fate The superficial mechanical and physical properties of matrix microenvironment as stem cell fate regulator Effects of mechanotransduction on stem cell behavior Modulation of stem cells behavior through bioactive surfaces Influence of controlled micro and nanoengineered surfaces on stem cell fate Nanostructured polymeric surfaces for stem cells Laser surface modification techniques and stem cells applications Plasma polymer deposition: a versatile tool for stem cell research Application of bioreactor concept and modeling techniques in bone regeneration and augmentation treatments Substrates and surfaces for control of pluripotent stem cell fate and function Application of biopolymer-based, surface modified devices in transplant medicine and tissue engineering Silk as a natural biopolymer for tissue engineering

Oral Delivery of Insulin

Author: T.A. Sonia
Publisher: Elsevier
ISBN: 1908818689
Format: PDF, ePub
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Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field

MATERIALS SCIENCE AND ENGINEERING

Author: V. RAGHAVAN
Publisher: PHI Learning Pvt. Ltd.
ISBN: 8120350928
Format: PDF
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This well-established and widely adopted book, now in its Sixth Edition, provides a thorough analysis of the subject in an easy-to-read style. It analyzes, systematically and logically, the basic concepts and their applications to enable the students to comprehend the subject with ease. The book begins with a clear exposition of the background topics in chemical equilibrium, kinetics, atomic structure and chemical bonding. Then follows a detailed discussion on the structure of solids, crystal imperfections, phase diagrams, solid-state diffusion and phase transformations. This provides a deep insight into the structural control necessary for optimizing the various properties of materials. The mechanical properties covered include elastic, anelastic and viscoelastic behaviour, plastic deformation, creep and fracture phenomena. The next four chapters are devoted to a detailed description of electrical conduction, superconductivity, semiconductors, and magnetic and dielectric properties. The final chapter on ‘Nanomaterials’ is an important addition to the sixth edition. It describes the state-of-art developments in this new field. This eminently readable and student-friendly text not only provides a masterly analysis of all the relevant topics, but also makes them comprehensible to the students through the skillful use of well-drawn diagrams, illustrative tables, worked-out examples, and in many other ways. The book is primarily intended for undergraduate students of all branches of engineering (B.E./B.Tech.) and postgraduate students of Physics, Chemistry and Materials Science. KEY FEATURES • All relevant units and constants listed at the beginning of each chapter • A note on SI units and a full table of conversion factors at the beginning • A new chapter on ‘Nanomaterials’ describing the state-of-art information • Examples with solutions and problems with answers • About 350 multiple choice questions with answers

Drug Delivery Nanosystems for Biomedical Applications

Author: Chandra P Sharma
Publisher: Elsevier
ISBN: 0323509231
Format: PDF
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Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

Frontiers in Biomaterials

Author: Shunsheng Cao
Publisher: Bentham Science Publishers
ISBN: 160805876X
Format: PDF
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Frontiers in Biomaterials: The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application, Volume 1 highlights the importance of biomaterials and their interaction with biological system. The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. This eBook covers the latest challenges on the biocompatibility of scaffold overtime after implantation and discusses the requirement of innovative technologies and strategies for the development of materials with long-lasting scaffold and biocompatibility functions. The contents of this eBook include chapters on cell-scaffold interactions in three dimensions, nanocrystalline diamond films for biomedical applications, bioceramics-design, synthesis and biological applications, polyester biomaterials for regenerative medicine, nanomaterials for skin regeneration and many more. This book is a valuable resource for MSc and PhD students , academic personnel and researchers seeking updated and critically important information on biomaterials and biomedical applications.

Intermolecular and Surface Forces

Author: Jacob N. Israelachvili
Publisher: Academic Press
ISBN: 9780080923635
Format: PDF, ePub
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This reference describes the role of various intermolecular and interparticle forces in determining the properties of simple systems such as gases, liquids and solids, with a special focus on more complex colloidal, polymeric and biological systems. The book provides a thorough foundation in theories and concepts of intermolecular forces, allowing researchers and students to recognize which forces are important in any particular system, as well as how to control these forces. This third edition is expanded into three sections and contains five new chapters over the previous edition. · starts from the basics and builds up to more complex systems · covers all aspects of intermolecular and interparticle forces both at the fundamental and applied levels · multidisciplinary approach: bringing together and unifying phenomena from different fields · This new edition has an expanded Part III and new chapters on non-equilibrium (dynamic) interactions, and tribology (friction forces)