Brain Stimulation

Author: Irving Reti
Publisher: John Wiley & Sons
ISBN: 111856829X
Format: PDF, Docs
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Brain stimulation technologies are both tools to probe brain function and to provide therapeutic options for patients with neuropsychiatric disease where pharmacological options are not viable. Although the field has been in existence for over seventy years, research interest in brain stimulation has been on the rise particularly in the last two decades. Brain Stimulation: Methodologies and Interventions is an introduction to the field of brain stimulation technology and its applications. The book explores how brain stimulating technologies work in the context of brain pathways that mediate normal and abnormal brain function. Chapters cover neuroanatomy and activitydependent changes in neuronal function triggered by brain stimulation, as well as applications of brain stimulation technologies themselves, including noninvasive procedures that rely on convulsive or seizure therapeutics, and non-convulsive therapies such as magnetic and electrical brain stimulation. Authored by an international group of leaders in the field, Brain Stimulation is a valuable resource for both neuroscience researchers and clinicians. KEY POINTS • Includes introductory chapters on relevant neuroanatomy • Covers both invasive and noninvasive brain stimulation techniques • Explains basic mechanisms and therapeutic applications • Written by an international team of leaders in the field • Illustrated in full color

Pediatric Brain Stimulation

Author: Adam Kirton
Publisher: Academic Press
ISBN: 0128020385
Format: PDF
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Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brain Edited by renowned leaders in the field of pediatric brain stimulation Presents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry

Mathematics for Healthcare

Author: Krasimira Tsaneva-Atanasova
Publisher: Frontiers Media SA
ISBN: 2889455777
Format: PDF, Kindle
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In 1996, and with extraordinary prescience, Panfilov and Holden had highlighted in their seminal book 'Computational Biology of the Heart' that biology was, potentially, the most mathematical of all sciences. Fast-forward 20 years and we have seen an explotion of applications of mathematics in not only biology, but healthcare that has already produced significant breakthroughs not imaginable more than 20 years ago. Great strides have been made in explaining through quantitative methods the underlying mechanisms of human disease, not without considerable ingenuity and effort. Biological mechanisms are bewildering: complex, ever evolving, multi-scale, variable, difficult to fully access and understand. This poses immense challenges to the computational physiology community that, nevertheless, has developed an impressive arsenal of tools and methods in a vertiginous race to combat disease with the tall order of improving human healthcare. Mechanistic models are now contending with the advent of machine learning in healthcare and the hope is that both approaches will be used synergistically since the complexity of human patophysiology and the difficulty of acquiring human datasets will require both, deductive and inductive methods. This Research Topic presents work that is currently at the frontier in computational physiology with a striking range of applications, from diabetes to graft failure and using a multitude of mathematical tools. This collection of articles represents a snapshot in a field that is moving a dizzying speed, bringing understanding of fundamental mechanism and solutions to healthcare problems experienced by healthcare systems all over the world.

Deep Brain Stimulation in Neurological and Psychiatric Disorders

Author: Daniel Tarsy
Publisher: Springer Science & Business Media
ISBN: 9781597453608
Format: PDF, Docs
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This important book discusses today’s most current and cutting-edge applications of Deep Brain Stimulation (DBS). The book begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections which underlie the application of DBS to neurological and psychiatric disorders. This is followed by proposed mechanisms of action of DBS based on functional neuroimaging and neurophysiologic studies in animals and man.

Parkinson s Disease Second Edition

Author: Ronald F. Pfeiffer
Publisher: CRC Press
ISBN: 1439807159
Format: PDF, ePub, Docs
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In recent years, considerable advances have been made in our knowledge and understanding of Parkinson's disease (PD). In particular, there has been an explosion of information regarding genetic contributions to the etiology of PD and an increased awareness of the importance of the non-motor features of the disease. Theories regarding the pathogenesis and pathophysiology of PD have also been refined, and new treatment modalities and advances implemented. Reflecting these changes, this second edition features new chapters devoted to genetic aspects of PD, non-motor features of the disease, and aspects of the pathophysiology, pathogenesis, and treatment of PD.

Psychology for Health Professionals

Author: Patricia Barkway
Publisher: Elsevier Health Sciences
ISBN: 072957797X
Format: PDF, ePub, Docs
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This book provides an introduction to psychology for allied health students and it encourages an understanding of the complex and interactive nature of the factors which influence an individual’s health behaviours and health outcomes. Through the use of real life examples, contemporary research and case studies students will be able to apply the material in the text to the health behaviours of the people they care for, their colleagues and themselves. Unlike many health psychology textbooks this new book examines individual personality and psychological theory within the social context of people’s lives. This approach is taken because of the increasing awareness that a person’s behaviour is not only influenced by internal biological and psychological factors, but also by external factors within the person’s social and physical environment. The first half of the book outlines psychological and other relevant theory whilst in the second half those theories are applied to health issues and healthcare practice. Chapters 1—5 presents psychological, lifespan and social theory; chapter 6 addresses the role and contribution of research to healthcare practice; and chapters 7—13 covers the psychological aspects of specific health encounters, issues and interventions. developmental psychology – theories of development and how do we study development along with problems of researching early lifespan development are also discussed. Behavioural interventions with children, adolescents and their families are highlighted models and theories which provide an understanding of and suggest strategies to change health behaviours are presented, as are explanations for human responses to stress, pain and loss critical thinking questions, case studies and examples of research are included throughout the text to encourage students to reflect on the application of theory to practice, and activities are provided for lecturers to use in the classroom learning objectives, critical reflection boxes, diagrams and figures to enhance learning, cases studies from different health professions, chapter summaries, glossaries, recommended reading lists, internet based resources, challenge questions and exercises Evolve website – the activities, case studies, testbanks and powerpoint presentations will complete the package and further demonstrate the integration of psychological principles within the health context

Brain Receptor Methodologies Pt A

Author: Paul J. Marangos
Publisher: Elsevier
ISBN: 0323152805
Format: PDF, ePub, Docs
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Brain Receptor Methodologies, Part A, General Methods and Concepts: Amines and Acetylcholine provides information pertinent to neurotransmitter and neuromodulator receptors in brain. This book explores the methodologies that can used to address several basic and clinical problems. Organized into two sections encompassing 18 chapters, this book starts with an overview of the receptor concept, which can be validated from indirect evidence obtained in studies of the quantitative aspects of drug antagonism. This text then examines the radioligand–receptor binding interactions. Other chapters consider immunocytochemistry, which has a primary role in determining the precise distribution of regulatory peptides to neural and endocrine elements of the diffuse neuroendocrine system. The final chapter discusses the use of the radioligand binding procedure for the study of muscarinic receptors, which has expanded the area of muscarinic receptor pharmacology. Biochemists, pharmacologists, physiologists, and researchers engaged in the fields of neurobiology and neuroscience will find this book extremely useful.

Medical Image Computing and Computer Assisted Intervention MICCAI 2004

Author: Christian Barillot
Publisher: Springer Science & Business Media
ISBN: 3540229760
Format: PDF, ePub, Docs
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The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the “Palais du Grand Large” conference center, September 26–29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pers on the multidisciplinary ?elds of medical image computing, comput- assisted intervention and medical robotics. The conference brings together cl- icians, biological scientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 516 full submissions (8 pages in length) and 101 short communications (2 pages) from 36 di?erent countries and 5 continents (see ?gures below). All submissions were reviewed by up to 4 external reviewers from the Scienti?c Review C- mittee and a primary reviewer from the Program Committee. All reviews were then considered by the MICCAI 2004 Program Committee, resulting in the acceptance of 235 full papers and 33 short communications.

The Neurobiology of Motivation and Reward

Author: James Stellar
Publisher: Springer Science & Business Media
ISBN: 1461580323
Format: PDF, ePub, Mobi
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This book was conceived many years ago as an abstract goal for a father-son team when the father was working in university administration and the son was just getting into the academic business. Eventually, the father returned to the laboratory, the son began to get his feet on the ground, and the goal became concrete. Now the work is finished, and our book enters the literature as, we hope, a valuable contribution to understanding the terribly complex and subtle problem of the neuro biology of motivated behaviors. We would also like the book to stand as a personal mark of a cooperative relationship between father and son. This special relationship between the authors gave us an extra dimension of pleasure in writing the book, and it would delight us if it gave anyone else an extra dimension of enjoyment from reading it. One thing we hope happens is that anyone or simply considering entering similar considering a similar partnership, of this book as encouragement. Such re fields, will take the existence lationships are highly satisfying if both parties take care to protect the partnership. When we actually sat down to write the book, we were humbled by the immense literature and the smallness of both our conceived space for putting it down and of our brains for processing all the information.

Neustart im Kopf

Author: Norman Doidge
Publisher: Campus Verlag
ISBN: 3593508397
Format: PDF, ePub, Docs
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Die erstaunlichen Fähigkeiten unseres Gehirns Unser Gehirn ist nicht - wie lange angenommen - eine unveränderliche Hardware. Es kann sich vielmehr auf verblüffende Weise umgestalten und sogar selbst reparieren - und das bis ins hohe Alter. Diese Erkenntnis ist die wohl sensationellste Entdeckung der Neurowissenschaften. "Dr. Doidge, ein hervorragender Psychiater und Forscher, erkundet die Neuroplastizität in Begegnungen mit Pionieren der Forschung und mit Patienten, die von den neuen Möglichkeiten der Rehabilitation profitiert haben. ... Das Buch ist ein absolut außergewöhnliches und hoffnungsvolles Zeugnis der Möglichkeiten des menschlichen Gehirns." Oliver Sacks "...ein faszinierender Abriss der jüngsten Revolution in den Neurowissenschaften!" The New York Times "Das Gehirn ist kein fertig verdrahteter Denkapparat, der im Laufe des Lebens immer weiter verschleißt. Es kann sich umorganisieren, umformen und manchmal kann es sogar wachsen. Der Psychologe Norman Doidge erklärt neueste Ergebnisse der Hirnforschung: Durch einfühlsam geschilderte Beispiele macht er sie für jedermann verständlich und nachvollziehbar." Deutschlandfunk