Cancer on Trial

Author: Peter Keating
Publisher: University of Chicago Press
ISBN: 0226428915
Format: PDF, Kindle
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Until the early 1960s, cancer treatment consisted primarily of surgery and radiation therapy. Most practitioners then viewed the treatment of terminally ill cancer patients with heroic courses of chemotherapy as highly questionable. The randomized clinical trials that today sustain modern oncology were relatively rare and prompted stiff opposition from physicians, who were loath to assign patients randomly to competing treatments. Yet today these trials form the basis of medical oncology. How did such a spectacular change occur? How did medical oncology pivot from a nonentity and, in some regards, a reviled practice to the central position it now occupies in modern medicine? In Cancer on Trial Peter Keating and Alberto Cambrosio explore how practitioners established a new style of practice, at the center of which lies the cancer clinical trial. Far from mere testing devices, these trials have become full-fledged experiments that have redefined the practices of clinicians, statisticians, and biologists. Keating and Cambrosio investigate these trials and how they have changed since the 1960s, all the while demonstrating their significant impact on the progression of oncology. A novel look at the institution of clinical cancer research and therapy, this book will be warmly welcomed by historians, sociologists, and anthropologists of science and medicine, as well as clinicians and researchers in the cancer field.

Cancer Patients Cancer Pathways

Author: Carsten Timmermann
Publisher: Palgrave Macmillan
ISBN: 1137272074
Format: PDF, Mobi
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The eleven essays in this volume examine cancer research and treatment as everyday practice in post-war Europe and North America. Rather than writing cancer's history as that of inevitable progress and obstacles overcome, these scholars emphasize how contingency, politics, and institutional interests have informed approaches to research and treatment. Focusing on the interface between individual patient trajectories and the evolving routines of research, therapy and care, the contributors bring together ethnographically-inflected historical and sociological observation with technically well-informed accounts of encounters between patients and professionals. The picture that emerges is one of cancers rather than Cancer, of patients rather than "The Patient," and of medical practices that are both experimental and routine. As cancer treatment has come to epitomize biomedicine, these essays speak to readers interested more broadly in understanding patients' experiences with large institutions, sophisticated technologies, and clinical research, and the way these experiences can shape treatment policies.

The Changing Faces of Childhood Cancer

Author: Joanna Baines
Publisher: Springer
ISBN: 113735352X
Format: PDF, ePub, Docs
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This book traces the development of British answers to the problem of childhood cancer. The establishment of the NHS and better training for paediatricians, meant children were given access to experimental chemotherapy, sending cure rates soaring. Children with cancer were thrust into the spotlight as individuals' stories of hope hit the headlines.

Philosophy of Molecular Medicine

Author: Giovanni Boniolo
Publisher: Routledge
ISBN: 1317378342
Format: PDF, Docs
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Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Caring for the Heart

Author: W Bruce Fye
Publisher: Oxford University Press
ISBN: 0199982376
Format: PDF, ePub, Mobi
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This groundbreaking book weaves together three important themes. It describes major developments in the diagnosis and treatment of heart disease in the twentieth century, explains how the Mayo Clinic evolved from a family practice in Minnesota into one of the world's leading medical centers, and reveals how the invention of new technologies and procedures promoted specialization among physicians and surgeons. Caring for the Heart is written for general readers as well as health care professionals, historians, and policy analysts. Unlike traditional institutional or disease-focused histories, this book places individuals and events in national and international contexts that emphasize the interplay of medical, scientific, technological, social, political, and economic forces that have resulted in contemporary heart care. Patient stories and media perspectives are included throughout to help general readers understand the medical and technological developments that are described. The book is a synthetic study, but it is written so that readers may pick and choose the chapters of most interest to them. Another feature of the book is that readers may follow the stories without looking at the notes. Those who are interested in delving deeper into the main topics will find a wealth of carefully chosen references that offer greater detail and additional perspectives. The descriptions and interpretations that fill the book benefit from the fact that the author has been a practicing cardiologist and medical historian for almost four decades. This is mainly a twentieth-century story, but it begins earlier--before there were physicians who were identified as cardiologists and at a time when medical specialization was just emerging in America. The final chapter, which addresses present-day concerns about health care costs, counterbalances earlier ones that might be read as celebrations of new technologies.

Cancer in the Twentieth Century

Author: David Cantor
Publisher: Johns Hopkins University Press
ISBN:
Format: PDF, ePub, Mobi
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Featuring works by leading medical historians on subjects such as the portrayal of cancer in the movies, feminist surgeons, risk factors for breast cancer, and the emergence of clinical trials, Cancer in the Twentieth Century will engage historians of medicine and public health as well as health policy analysts, medical sociologists and anthropolog

Principles and Practice of Gastrointestinal Oncology

Author: David Kelsen
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781776172
Format: PDF, ePub, Mobi
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Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care. The initial section, Principles of Gastrointestinal Oncology, includes an expanded radiation oncology chapter, an extensively revised cancer genetics chapter, and a completely rewritten medical oncology chapter emphasizing new agents. Subsequent sections focus on esophageal, gastric, pancreatic, hepatocellular, biliary tree, and colorectal cancer. Coverage of each anatomic site includes epidemiology, screening, and prevention; molecular biology and genetics; pathology; anatomy and staging; and clinical management. The final section on uncommon cancers includes new chapters on neuroendocrine tumors and small bowel cancers. A companion Website provides instant access to the complete, fully searchable text.

Principles and Practice of Surgical Oncology

Author: Howard Silberman
Publisher: Lippincott Williams & Wilkins
ISBN: 1451153236
Format: PDF, Docs
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Principles and Practice of Surgical Oncology uniquely emphasizes a multidisciplinary, integrated approach to the treatment of solid tumors. It presents treatment strategies that combine surgery with preoperative or postoperative adjunctive chemotherapy, hormonal therapy, and/or radiation therapy to achieve optimal outcome. The book features contributions from surgeons, basic scientists, pathologists, radiologists, radiation therapists, and medical oncologists and offers a comprehensive presentation of genetics, molecular biology, pathogenesis, and multimodal therapeutic approaches. A unique feature of the book is a commentary following each chapter, which describes alternative approaches and discusses controversial areas of current therapy. A companion Website will offer the fully searchable text with images.

Cancer Management in Small Animal Practice E Book

Author: Carolyn J. Henry
Publisher: Elsevier Health Sciences
ISBN: 1437701981
Format: PDF, Mobi
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Cancer Management in Small Animal Practice provides you with all the tools needed to diagnose, stage, and manage the many different disease entities known as "cancer." This manual is designed to provide you with easy-to-access, clinically relevant details for complete care of the small animal cancer patient, while considering the needs, concerns, and capabilities of the client. It provides quick reference sections for information not included in current oncology texts, including drug interactions and resources for participation in clinical trials. All information is well referenced and the reference section on the accompanying website includes links to the original and related articles. The latest information including diagnostic procedures, treatment modalities, and outcome predictions to help clients make the best decisions for their pets. Expert contributors, renowned for clinical, as well as academic and research expertise, offer a wide breadth and depth of expertise. Full-color format provides accurate visual depictions of specific diseases and procedures to enhance your diagnostic capabilities. Key Points highlight critical information, enabling quick, easy access. Systems approach to diagnosis and management offers logical, systematic, head-to-tail procedure for accurate diagnosis, treatment, and prognosis. Extensive discussions of supportive care limit adverse events and increase patient survival and puts emergency information at the practitioner’s fingertips. Suggested readings highlight the latest information for further investigation and research. Comprehensive drug safety guidelines thoroughly discuss all information required to safely handle and administer cancer drugs. Helpful drug formularies offer available formulations, recommended dosages, toxicities, and relative costs. Chapter on how to access clinical trials provides helpful information and hope for patients and their caregivers.