Chirality in Biological Nanospaces

Author: Nilashis Nandi
Publisher: CRC Press
ISBN: 1439840024
Format: PDF, ePub, Mobi
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Chirality is widely studied and omnipresent in biological molecules. However, how the retention of enantiomeric forms persists in many life processes without racemization is still unclear, and the molecular understanding of the stringent chiral specificity in enzymatic reactions is sparse. An overview of the influence of chirality in driving reactions within enzymatic cavities, Chirality in Biological Nanospaces: Reactions in Active Sites covers: Influences of molecular chirality on the structure of the active site and network of interactions to drive reactions with improved speed, accuracy, and efficiency The conserved features of the organization of the active site structures of enzymes The intricate interplay of electrostatic, hydrophobic, and van der Waals interactions Interactions between the active site residues and the substrate molecules Despite being time-consuming and expensive, trial-and-error is often the primary method used to develop synthetic enzymes. This book describes methods that combine crystallographic studies with electronic structure-based computational analysis. These methods may lead to future elucidation of new drugs that can target biological active sites with better efficacy and can be used to design custom-made novel biocytes with improved efficiency.

Encyclopedia of Biocolloid and Biointerface Science 2 Volume Set

Author: Hiroyuki Ohshima
Publisher: John Wiley & Sons
ISBN: 1118542762
Format: PDF, Kindle
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This encyclopedia uniquely concentrates on biocolloids and biointerfaces rather than the broader field of colloid and interface science. Biocolloids and biointerfaces are the youngest but increasingly prominent studied area of colloid and interface science, and this encyclopedia uses "soft particles" and "soft interface" as surface models in observing phenomena in biological systems. Provides a detailed description of the fundamental theories, dealing with the physicochemical and theoretical aspects of biocolloid and biointerface science Offers a detailed description of soft interfaces or surfaces Includes detailed description of applications of fundamental biocolloid and biointerface theories to nano-, bio, and environmental sciences A useful and timely resource for researchers and graduates in the field of biocolloid and biointerface science, as well as engineers in the field of nanotechnology, bioscience, and environmental science.

Biochirality

Author: Pedro Cintas
Publisher: Springer
ISBN: 3642376266
Format: PDF, ePub
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Early History of the Recognition of Molecular Biochirality, by Joseph Gal, Pedro Cintas Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich Chemical and Physical Models for the Emergence of Biological Homochirality, by son E. Hein, Dragos Gherase, Donna G. Blackmond Biomolecules at Interfaces: Chiral, Naturally, by Arántzazu González-Campo and David B. Amabilino Stochastic Mirror Symmetry Breaking: Theoretical Models and Simulation of Experiments, by Celia Blanco, David Hochberg Self-Assembly of Dendritic Dipeptides as a Model of Chiral Selection in Primitive Biological Systems, by Brad M. Rosen, Cécile Roche, Virgil Percec Chirality and Protein Biosynthesis, by Sindrila Dutta Banik, Nilashis Nandi

Chirality in Supramolecular Assemblies

Author: F. Richard Keene
Publisher: John Wiley & Sons
ISBN: 1118867327
Format: PDF, Kindle
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Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overview of this important and rapidly developing interdisciplinary field. Topics covered include: Origins of molecular and topological chirality Homochirogenesis Chirality in crystallinity Host-guest behavior Chiral influences in functional materials Chirality in network solids and coordination solids Aspects of chirality at interfaces Chirality in organic assemblies Chirality related to biocatalysis and enzymes in organic synthesis. This book is a valuable reference for researchers in the molecular sciences, materials science and biological science working with chiral supramolecular systems. It provides summaries and special insights by acknowledged international experts in the various fields.

Design and Applications of Single Site Heterogeneous Catalysts

Author: Sir John Meurig Thomas
Publisher: World Scientific Publishing Company
ISBN: 1848169299
Format: PDF, Docs
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For far too long chemists and industrialists have relied on the use of aggressive reagents such as nitric and sulphuric acids, permanganates and dichromates to prepare the massive quantities of both bulk and fine chemicals that are needed for the maintenance of civilised life — materials such as fuels, fabrics, foodstuffs, fertilisers and pharmaceuticals. Such aggressive reagents generate vast quantities of environmentally harmful and often toxic by-products, including the oxides of nitrogen, of metal oxides and carbon dioxide. Now, owing to recent advances made in the synthesis of nanoporous solids, it is feasible to design new solid catalysts that enable benign, mild oxidants to be used, frequently without utilising solvents, to manufacture the products that the chemical, pharmaceutical, agro- and bio-chemical industries require. These new solid agents are designated single-site heterogeneous catalysts (SSHCs). Their principal characteristics are that all the active sites present in the high-area solids are identical in their atomic environment and hence in their energy of interaction with reactants, just as in enzymes. Single-site heterogeneous catalysts now occupy a position of growing importance both academically and in their potential for commercial exploitation. This text, the only one devoted to such catalysts, dwells both on principles of design and on applications, such as the benign synthesis of nylon 6 and vitamin B3. It equips the reader with unifying insights required for future catalytic adventures in the quest for sustainability in the materials used by humankind. Anyone acquainted with the language of molecules, including undergraduates in the physical and biological sciences, as well as graduates in engineering and materials science, should be able to assimilate the principles and examples presented in this book. Inter alia, it describes how clean technology and ‘green’ processes may be carried out in an environmentally responsible manner. Contents:Basics and Background:Introduction to the Salient Features of Single-Site Heterogeneous CatalystsLessons from the Biological World: The Kinship between Enzymes and Single-Site Heterogeneous CatalystsDistinctions between Single-Site Heterogeneous Catalysts and Immobilized Homogeneous CatalystsMicroporous Open Structures:Microporous Open Structures for the Design of New Single-Site Heterogeneous CatalystsSingle-Site Heterogeneous Catalysts for the Production of Pharmaceuticals, Agrochemicals, Fine and Bulk ChemicalsMesoporous Open Structures:Epoxidations and Sustainable Utilization of Renewable Feedstocks, Production of Vitamin E Intermediates, Conversion of Ethene to Propene and Solvent-Free, One-Step Synthesis of EstersExploiting Nanospace for Asymmetric ConversionsMultinuclear, Bimetallic Nanocluster Catalysts Readership: Students, professionals, some industrial scientists.

Directory of Graduate Research

Author: American Chemical Society. Committee on Professional Training
Publisher:
ISBN:
Format: PDF, Kindle
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Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Feedback That Works

Author: Sloan R. Weitzel
Publisher: Center for Creative Leadership
ISBN: 1604910399
Format: PDF, Docs
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Effective feedback, whether it's meant for your boss, your peers, or your direct reports, is built around three ideas. One, focus on the situation. Two, describe the other person's behavior you observed in that situation. And third, describe the impact that behavior had on you. The result is a message that is clear and that can inspire action and productive change.

Feedback That Works How to Build and Deliver Your Message German

Author: Sloan Weitzel
Publisher: Center for Creative Leadership
ISBN: 1604917571
Format: PDF, Mobi
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Ganz gleich, welche Stellung Sie in Ihrer Organisation innehaben - ob Fachgebietsleiter, Teamleiter oder Führungskraft auf höchster Ebene -, die Fähigkeit, sinnvolles und wirkungsvolles Feedback zu geben, ist ein maßgeblicher Beitrag zur Entwicklung von Mitarbeitern sowie zur Bewältigung von Aufgaben. Der Schlüssel zu wirksamem Feedback ist die richtige Formulierung und Übermittlung detailgenauer Botschaften auf der Grundlage beobachteter Leistungen. Ihr Feedback sollte dem Empfänger genau zu verstehen geben, was er bzw. Chance, dass der Feedback-Empfänger motiviert und bereit ist, bestimmte leistungsfördernde Verhaltensweisen anzunehmen bzw. fortzusetzen oder leistungshemmendes Verhalten zu unterlassen. Der vorliegende Ratgeber erläutert, wie Sie wirksames Feedback geben, Ihre Botschaft richtig formulieren und diese zu einem angemessenen Zeitpunkt übermitteln können. Mithilfe der hier beschriebenen Methoden und Beispiele wird Ihr Feedback zu einem entwicklungsfördernden Tool - sowohl für andere als auch für Sie selbst.

Organische Chemie

Author: Hans Peter Latscha
Publisher: Springer-Verlag
ISBN: 3662461803
Format: PDF, Mobi
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Die Reihe Chemie Basiswissen stellt den gesamten Wissensstoff für das Bachelorstudium Chemie dar. Studenten mit Chemie im Nebenfach und Studierende des höheren Lehramtes dient sie zur Examensvorbereitung. Der Band II, Organische Chemie, präsentiert den Stoff dieses Gebietes in kurzer und übersichtlicher Form. Das didaktische Konzept und die am Curriculum orientierte Stoffauswahl haben das Buch bei Haupt- und Nebenfachstudenten der Chemie sowie Studierenden des höheren Lehramtes beliebt gemacht. Die 7. Auflage wurde vollständig durchgesehen und aktualisiert und um ein Kapitel über wichtige Medikamente erweitert.