Clinical Trials

Author: Lorna Speid
Publisher: OUP USA
ISBN: 019973416X
Format: PDF
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Every year healthy volunteers and patients worldwide take part in clinical trials. Many of them will be bewildered by the jargon and medical terminology used during their participation. This book seeks to de-mystify the process of drug development in general, and clinical trials in particular.

Clinical Trials

Author: Lorna Speid, PhD
Publisher: OUP USA
ISBN: 9780199734160
Format: PDF, Docs
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Every year, hundreds of thousands of healthy volunteers and patients worldwide undertake the journey through the maze that can be clinical trials. Research participants take part in clinical trials for a variety of reasons. The healthy volunteers may be seeking extra money to pay off college tuition, or they may know someone who is suffering and would potentially benefit from the results of the trial. The patient who is terminally ill might participate in a clinical trial simply as a last hope for a cure. Whatever the goals, though, most participants will experience the same sense of bewilderment as they encounter the jargon and medical terminology that they will hear and have to read about and understand during the course of the clinical trial. Clinical Trials: What Patients and Volunteers Need to Know demystifies the entire process, focusing on the process of drug development, and the clinical trial itself. Writing from a lifetime of experience, the author provides important questions to ask those running a clinical trial, key definitions and terms for a participant to know and understand, as well as anecdotes illustrating the clinical trial process. The author also grapples with the idea of "informed consent," providing mechanisms for patients and volunteers to feel fully informed before signing up for the trial. A vital resource for those who are considering enrolling in a clinical trial, or for the parents, friends, or relatives of those involved in a clinical trial, this book takes away the mystery and allows the participant to enter a clinical trial feeling both informed and confident.

Clinical Trials

Author: Lorna Speid, Ph.D
Publisher: Oxford University Press
ISBN: 0199750599
Format: PDF, Docs
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Every year, hundreds of thousands of healthy volunteers and patients worldwide undertake the journey through the maze that can be clinical trials. Research participants take part in clinical trials for a variety of reasons. The healthy volunteers may be seeking extra money to pay off college tuition, or they may know someone who is suffering and would potentially benefit from the results of the trial. The patient who is terminally ill might participate in a clinical trial simply as a last hope for a cure. Whatever the goals, though, most participants will experience the same sense of bewilderment as they encounter the jargon and medical terminology that they will hear and have to read about and understand during the course of the clinical trial. Clinical Trials: What Patients and Volunteers Need to Know demystifies the entire process, focusing on the process of drug development, and the clinical trial itself. Writing from a lifetime of experience, the author provides important questions to ask those running a clinical trial, key definitions and terms for a participant to know and understand, as well as anecdotes illustrating the clinical trial process. The author also grapples with the idea of "informed consent," providing mechanisms for patients and volunteers to feel fully informed before signing up for the trial. A vital resource for those who are considering enrolling in a clinical trial, or for the parents, friends, or relatives of those involved in a clinical trial, this book takes away the mystery and allows the participant to enter a clinical trial feeling both informed and confident.

Critical Government Documents on Health Care

Author: Don Philpott
Publisher: Rowman & Littlefield
ISBN: 1598887440
Format: PDF, ePub, Mobi
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Critical Government Documents on Health Care reviews of many of the major health issues facing us today. The book does not argue any one viewpoint. Instead, it is an attempt to gather together information from as many sources as possible and presents arguments for and against the issues covered so that you the reader can come to your own conclusions. Areas covered include killer diseases such as heart disease, cancer, stroke, respiratory diseases, and obesity. It discusses the arguments for and against immunization and looks at issues which impact your health such as the environment and pollution. There is a detailed section on Alzheimer’s disease and other forms of dementia and the problems it poses for healthcare providers and caregivers, and this is coupled with all the other issues that arise from a growing aging population. Finally, the book discusses external threats such as pandemics, Ebola, and other diseases that can rapidly spread from continent to continent and what is and should be done to contain them. About the Series: The Critical Documents Series looks at critical issues of our times. It provides non-partisan information with no spin about critical players, events, and information from and about Washington from as many sources as possible — from scientific journals and government reports to political manifestos and lobby group publications. It presents arguments for and against the issues covered so that you the reader can come to your own conclusions.

Healthy Volunteers in Commercial Clinical Drug Trials

Author: Shadreck Mwale
Publisher: Springer
ISBN: 3319592149
Format: PDF, Mobi
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This book provides a richly detailed contribution to the understanding of healthy volunteer experiences in clinical drug trials in the UK. Contemporary society, especially the West, has seen a significant increase in the production and use of pharmaceutical products, particularly for disease treatment. However, despite the large numbers of people involved, particularly in the UK, very little is known about their experiences in commercial phase I clinical drug trials. Shadreck Mwale critiques common conceptions of the terms ‘volunteer’ and ‘altruism’ as used in policy and practice of human involvement in clinical trials and calls for an awareness of the complexity of the terms and how the social contexts participants find themselves in shape acts of voluntarism. Based on extensive empirical evidence and conceptual analysis, the book presents new insights into the lives of healthy volunteers, challenges bioethical conceptions and generates new frameworks for policy and practice of FIHCTs. It will be of particular interest to scholars and practitioners in the wider social sciences, medical Sociology and medical anthropology, pharmacology and bioethics.

Les mots cl s de la sant

Author: Joëlle Rouanet-Laplace
Publisher: Editions Bréal
ISBN: 9782842919948
Format: PDF, Kindle
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Ce Lexipro rassemble les mots indispensables pour communiquer en anglais dans le domaine de la santé dans une perspective professionnelle. Il comprend le vocabulaire médical général classé selon les principaux domaines de la médecine, le vocabulaire relevant des établissements de santé et enfin celui de la santé publique. Sans prétendre être exhaustif, ce lexique est conçu comme un outil de travail présentant un panorama aussi large que possible, base indispensable pour une exploration plus fine des thèmes abordés.

Phase I Cancer Clinical Trials

Author: Elizabeth A. Eisenhauer
Publisher: Oxford University Press
ISBN: 0199359032
Format: PDF, Kindle
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Phase I trials are a critical first step in the study of novel cancer therapeutic approaches. Their primary goals are to identify the recommended dose, schedule and pharmacologic behavior of new agents or new combinations of agents and to describe the adverse effects of treatment. In cancer therapeutics, such studies have particular challenges. Due to the nature of the effects of treatment, most such studies are conducted in patients with advanced malignancy, rather than in healthy volunteers. Further, the endpoints of these trials are usually measures adverse effects rather than molecular target or anti-tumor effects. These factors render the design, conduct, analysis and ethical aspects of phase I cancer trials unique. As the only comprehensive book on this topic, Phase I Cancer Clinical Trials is a useful resource for oncology trainees or specialists interested in understanding cancer drug development. New to this edition are chapters on Phase 0 Trials and Immunotherapeutics, and updated information on the process, pitfalls, and logistics of Phase I Trials

It s Great Oops No It Isn t

Author: Ronald Gauch
Publisher: Springer Science & Business Media
ISBN: 1402089074
Format: PDF, ePub, Docs
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The truth is, few people know the first thing about clinical research. The public reads about a medical research project that announces unbelievable results for a miraculous drug. Some years later, another investigation completely wipes out those initial favorable findings. Hormones Cut Women’s Risk of Heart Disease (San Francisco Chronicle, 1994) Hormones Don’t Protect Women from Heart Disease, Study Says (Washington Post, 2001) The people are confused because we do not understand the process behind these conflicting results. Our health, and in fact, our very lives are dependent on clinical trials, but we know little about them. This book explains the issues the public needs to be aware of when it comes to clinical research. It uncovers the problems in medical investigations that can not be overcome no matter how much care and diligence medical researchers bring to a research project. The basic premise that drives the writing is that it is impossible for medical researchers to guarantee that they can get all the right answers from a single study. No matter how good the investigators are, no matter how well a study is planned, no matter how carefully the plans are executed and no matter how conscientiously the results are analyzed and interpreted – the answer may still be wrong. The deck is stacked against medical researchers and the public – you – should be skeptical of the results no matter how impressive they seem on the surface.

Clinical Pharmacology

Author: Morris J. Brown
Publisher: Elsevier Health Sciences
ISBN: 0702051136
Format: PDF, Mobi
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A thorough knowledge of pharmacological and therapeutic principles is vital if drugs are to be used safely and effectively for increasingly informed patients. Those who clearly understand how drugs get into the body, how they produce their effects, what happens to them in the body, and how evidence of their therapeutic effect is assessed, will choose drugs more skilfully, and use them more safely and successfully than those who do not. Now in a fully revised 11th edition, Clinical Pharmacology is essential reading for undergraduate medical students, junior doctors and anyone concerned with evidence-based drug therapy. Introductory first three sections cover general principle of clinical pharmacology; five subsequent sections cover drug treatment of disease organised by body system. Retains approachable style set by the original author, Professor Laurence. Emphasis throughout is on evidence-based and safe drug prescribing. Indian Advisory Board will ensure content reflects the needs of the devloping world.

Clinical Trials

Author: J. Joseph Giffels
Publisher: Demos Medical Pub
ISBN:
Format: PDF, ePub
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This booklet is designed for use in clinical trials of all new therapies. It is designed to assist the physician in working with patients in clinical trials & answers the many questions that they have before making the decision to participate. This booklet will help patients to understand some of the basics of clinical research, providing answers to all key questions: * what a clinical trial is * the role & rights of a volunteer subject * what they should consider when deciding whether to participate * what informed consent is * what questions they should ask about the study * what they can expect from your participation & what you should not expect.