Colloids in Drug Delivery

Author: Monzer Fanun
Publisher: CRC Press
ISBN: 9781439818268
Format: PDF, Kindle
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Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world’s leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research. The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research. Topics discussed include: The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases Classification and application of colloidal drug delivery systems in tumor targeting The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery Examining topics necessary to the critical evaluation of a drug candidate’s potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves. All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.

Colloid and Interface Science in Pharmaceutical Research and Development

Author: Hiroyuki Ohshima
Publisher: Elsevier
ISBN: 0444626085
Format: PDF, ePub, Mobi
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Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement. The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs. Provides a clear description of the fundamentals of colloid and interface science relevant to drug research and development Explains the physicochemical/colloidal basis of pharmaceutical science Lists modern experimental characterization techniques, provides analytical equations and explanations on analyzing the experimental data Describes the most advanced techniques, AFM (Atomic Force Microscopy), SFA (Surface Force Apparatus) in detail

Nanocolloids

Author: Margarita Sanchez-Dominguez
Publisher: Elsevier
ISBN: 0128017589
Format: PDF, Mobi
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Nanocolloids: A Meeting Point for Scientists and Technologists presents an easy-to-read approach to current trends in nanoscale colloid chemistry, which offers relatively simple and economically feasible ways to produce nanomaterials. Nanocolloids have been the subjects of major development in modern technology, with many current and future applications. The book helps scientists and technologists to understand the different aspects of modern nanocolloid science. It outlines the underlying fundamental principles of nanocolloid science and covers applications ranging from emulsions to dispersions and suspensions. You will find details on experimental techniques and methods for the synthesis and characterization of nanocolloids, including the latest developments in nanoemulsions and nanoparticles. Edited by leading academics with over 10 years’ experience in the field of colloid and surfactant science. Each chapter is authored by recognized experts in the field. Outlines the underlying fundamental science behind nanocolloids. Provides comprehensive coverage of current topics and potential applications in nanocolloid science. Presents a multidisciplinary approach to help chemical engineers, chemists, physicists, materials scientists and pharmacologists, form an in-depth understanding of nanocolloid science.

Colloids in Biotechnology

Author: Monzer Fanun
Publisher: CRC Press
ISBN: 9781439830819
Format: PDF, Docs
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Colloids show great potential in a wide variety of applications, including drug delivery and medical imaging, and the design and fabrication of colloid systems has attracted considerable interest in the research community. Colloids in Biotechnology describes developments in the field of biotechnological applications in the past decade and bridges the gap between these research efforts and commercially viable options. Highlights the role of colloids in a plethora of biotechnical applications Striking a balance between theory and experiment, between principles and applications, and between molecular and physical approaches to the subject, the book assembles contributions from an international community of colloid scientists to provide a comprehensive reference on the role of colloids in biotechnology and biomedicine. The authors discuss new types of biosurfactants; mixtures of surfactants; and peptides, proteins, and polyelectrolytes. They also describe the formation and properties of magnetic colloids and review their applications in chemical biology and medicine. They highlight current progress in the design of self-assembled materials for biotechnology, and they also cover the formation of nanofibres and the use of sol-gel technology in biology. Contains contributions from a diverse team of researchers The chapter authors have been given the freedom to present the spectrum of the relevant science, from pure to applied, in their particular topic. The compilation of this vast experience makes this text a valuable reference for those working in research and development in a range of technologies as well as academic scientists in the colloid and surface science field.

Surfactant Science and Technology

Author: Laurence S. Romsted
Publisher: CRC Press
ISBN: 1439882959
Format: PDF, Docs
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Surfactant research explores the forces responsible for surfactant assembly and the critical industrial, medical, and personal applications, including viscosity control, microelectronics, drug stabilization, drug delivery, cosmetics, enhanced oil recovery, and foods. Surfactant Science and Technology: Retrospects and Prospects, "a Festschrift in honor of Dr. Kash Mittal," provides a broad perspective with chapters contributed by leaders in the fields of surfactant-based physical, organic, and materials chemistries. Many of the authors participated in a special symposium in Melbourne, Australia, honoring Kash Mittal’s 100th edited book at the 18th Surfactants in Solution (SIS) meeting. Each chapter provides an overview of a specific research area, with discussions on past, present, and future directions. The book is divided into six parts. Part I reviews the evolution of theoretical models for surfactant self-assembly, and introduces a model for interpreting ion-specific effects on aggregate properties. Part II focuses on interactions of surfactant solutions with solid supports; uses contact angles to understand hydrophobic/hydrophilic changes in a lipid layer; uses surface tension to understand molecular arrangements at interfaces; reviews spreading phenomena; discusses pattern formation on solid surfaces; and applies tensiometry to probe flavor components of espresso. Part III discusses novel DNA-based materials, multifunctional poly(amino acid)s–based graft polymers for drug delivery, and polymeric surfactants for stabilizing suspensions and emulsions. Part IV introduces farm-based biosurfactants from natural products and "greener" biosurfactants from bacteria. Part V explores lyotropic liquid crystals and their applications in triggered drug release; microemulsion properties and controlled drug release; the role of hydrotopes in formulations and in enhancing solubilization in liquid crystals; the potential of ionic liquids to generate tunable and selective reaction media; and provides an overview of stimuli-responsive surfactants. Focusing on emulsions, Part VI reviews the design of emulsion properties for various commercial applications, the role of surfactants in the oil and gas industries, and surfactant mechanisms for soil removal via microemulsions and emulsification.

Colloidal Drug Delivery Systems

Author: Jorg Kreuter
Publisher: CRC Press
ISBN: 9780824792145
Format: PDF, Mobi
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This volume provides a single-source of reviews for all the important colloidal drug delivery systems, including nanoparticles, liposomes, niosomes, microemulsions and ointments. Over 1000 bibliographic citations, as well as tables, drawings, equations and photographs, are provided. Arranged in order of increasing physical complexity, this work analyzes developments in the field.

Colloidal Biomolecules Biomaterials and Biomedical Applications

Author: Abdelhamid Elaissari
Publisher: CRC Press
ISBN: 0824757068
Format: PDF
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Colloidal Biomolecules, Biomaterials, and Biomedical Applications is an authoritative presentation of established and recent techniques promising to revolutionize the areas of biomedical diagnostics, therapeutics, pharmaceutics, and drug delivery. This exceptional book details an original homogeneous assay for biomolecule detection and capture through duplex colloid particles, as well as new methods for utilizing peptides in particle agglutination. Featuring contributions from over 30 prominent researchers, it investigates physical studies of the agglutination of sensitive latexes, and indicates benefits to drug delivery through supercritical fluid process production of polymer particles.

Colloidal Silica

Author: Horacio E. Bergna
Publisher: CRC Press
ISBN: 1420028707
Format: PDF
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In spite of the apparent simplicity of silica’s composition and structure, scientists are still investigating fundamental questions regarding the formation, constitution, and behavior of colloidal silica systems. Colloidal Silica: Fundamentals and Applications introduces new information on colloid science related to silica chemistry as well as theoretical and experimental aspects of significant areas of colloidal silica science and technology. This resource is dedicated to helping researchers find new uses of silica and answers to practical problems as its industrial use continues to grow steadily in traditional and novel areas. Written by leading silica scientists around the world, this book reflects developments in the field since silica scientist Ralph K. Iler published his authoritative book on silica chemistry in 1979. It discusses properties and methods of characterization, synthesis, and preparation of silica in terms of industrial applications. Following an analysis of the surface chemistry of various silicas, the book explores methods for measuring particle size and useful characterization techniques for determining structure, stability, and reactivity. The authors then focus on various studies, analytical methods, and current applications involving silica gels and powders, silica coatings, colloidal silica, and sol-gel technology. Colloidal Silica: Fundamentals and Applications features up-to-date material relating to fields as diverse as catalysis, metallurgy, electronics, glass, ceramics, paper and pulp technology, optics, elastomers, food, health care, and industrial chromatography. It is ideal for scientists interested in silica chemistry and physics as well as those not familiar with the subject.

Essential Chemistry for Formulators of Semisolid and Liquid Dosages

Author: Vitthal S. Kulkarni
Publisher: Academic Press
ISBN: 012801072X
Format: PDF
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A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations. Unique coverage of the underlying chemistry that makes possible stable dosages Quality content written by experienced experts from the drug development industry Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products

Colloidal Science of Flotation

Author: Ahn Nguyen
Publisher: CRC Press
ISBN: 1482276410
Format: PDF, ePub
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Keeping pace with explosive developments in the field, Colloidal Science of Flotation reviews and updates the fundamentals of the bubble-particle collection phenomenon using a self-consistent approach that helps readers understand the hydrodynamic aspects of bubble-particle collection. The authors examine bubble rise velocity, water velocity around air bubbles, the thinning of intervening liquid films, the stability of particle-bubble aggregates, and macroscopic processes in froth. They also survey the applicability of emerging technologies in industrial flotation deinking, wastewater treatment, flotation of plastics, and improvements in minerals and coal flotation.