Design and Analysis of Experiments with R

Author: John Lawson
Publisher: CRC Press
ISBN: 1498728480
Format: PDF, Mobi
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Design and Analysis of Experiments with R presents a unified treatment of experimental designs and design concepts commonly used in practice. It connects the objectives of research to the type of experimental design required, describes the process of creating the design and collecting the data, shows how to perform the proper analysis of the data, and illustrates the interpretation of results. Drawing on his many years of working in the pharmaceutical, agricultural, industrial chemicals, and machinery industries, the author teaches students how to: Make an appropriate design choice based on the objectives of a research project Create a design and perform an experiment Interpret the results of computer data analysis The book emphasizes the connection among the experimental units, the way treatments are randomized to experimental units, and the proper error term for data analysis. R code is used to create and analyze all the example experiments. The code examples from the text are available for download on the author’s website, enabling students to duplicate all the designs and data analysis. Intended for a one-semester or two-quarter course on experimental design, this text covers classical ideas in experimental design as well as the latest research topics. It gives students practical guidance on using R to analyze experimental data.

Design of Experiments

Author: Max Morris
Publisher: CRC Press
ISBN: 1439894906
Format: PDF, ePub
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Offering deep insight into the connections between design choice and the resulting statistical analysis, Design of Experiments: An Introduction Based on Linear Models explores how experiments are designed using the language of linear statistical models. The book presents an organized framework for understanding the statistical aspects of experimental design as a whole within the structure provided by general linear models, rather than as a collection of seemingly unrelated solutions to unique problems. The core material can be found in the first thirteen chapters. These chapters cover a review of linear statistical models, completely randomized designs, randomized complete blocks designs, Latin squares, analysis of data from orthogonally blocked designs, balanced incomplete block designs, random block effects, split-plot designs, and two-level factorial experiments. The remainder of the text discusses factorial group screening experiments, regression model design, and an introduction to optimal design. To emphasize the practical value of design, most chapters contain a short example of a real-world experiment. Details of the calculations performed using R, along with an overview of the R commands, are provided in an appendix. This text enables students to fully appreciate the fundamental concepts and techniques of experimental design as well as the real-world value of design. It gives them a profound understanding of how design selection affects the information obtained in an experiment.

Statistics for Technology

Author: Chris Chatfield
Publisher: CRC Press
ISBN: 9780412253409
Format: PDF, Docs
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One of the most popular introductory texts in its field, Statistics for Technology: A Course in Applied Studies presents the range of statistical methods commonly used in science, social science, and engineering. The mathematics are simple and straightforward; statistical concepts are explained carefully; and real-life (rather than contrived) examples are used throughout the chapters. Divided into three parts, the Introduction describes some simple methods of summarizing data. Theory examines the basic concepts and theory of statistics. Applications covers the planning and procedures of experiments, quality control, and life testing. Revised throughout, this Third Edition places a higher priority on the role of computers in analysis, and many new references have been incorporated. A new appendix describes general methods of tackling statistical problems, including guidance on literature searching and report writing.

Design and Analysis of Experiments with SAS

Author: John Lawson
Publisher: CRC Press
ISBN: 1420060600
Format: PDF, Docs
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A culmination of the author’s many years of consulting and teaching, Design and Analysis of Experiments with SAS provides practical guidance on the computer analysis of experimental data. It connects the objectives of research to the type of experimental design required, describes the actual process of creating the design and collecting the data, shows how to perform the proper analysis of the data, and illustrates the interpretation of results. Drawing on a variety of application areas, from pharmaceuticals to machinery, the book presents numerous examples of experiments and exercises that enable students to perform their own experiments. Harnessing the capabilities of SAS 9.2, it includes examples of SAS data step programming and IML, along with procedures from SAS Stat, SAS QC, and SAS OR. The text also shows how to display experimental results graphically using SAS ODS graphics. The author emphasizes how the sample size, the assignment of experimental units to combinations of treatment factor levels (error control), and the selection of treatment factor combinations (treatment design) affect the resulting variance and bias of estimates as well as the validity of conclusions. This textbook covers both classical ideas in experimental design and the latest research topics. It clearly discusses the objectives of a research project that lead to an appropriate design choice, the practical aspects of creating a design and performing experiments, and the interpretation of the results of computer data analysis. SAS code and ancillaries are available at http://lawson.mooo.com

Encyclopedia of Bioinformatics and Computational Biology

Author:
Publisher: Elsevier
ISBN: 0128114320
Format: PDF, Mobi
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Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Probability and Statistics with R

Author: Maria Dolores Ugarte
Publisher: CRC Press
ISBN: 158488892X
Format: PDF, Kindle
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Designed for an intermediate undergraduate course, Probability and Statistics with R shows students how to solve various statistical problems using both parametric and nonparametric techniques via the open source software R. It provides numerous real-world examples, carefully explained proofs, end-of-chapter problems, and illuminating graphs to facilitate hands-on learning. Integrating theory with practice, the text briefly introduces the syntax, structures, and functions of the S language, before covering important graphically and numerically descriptive methods. The next several chapters elucidate probability and random variables topics, including univariate and multivariate distributions. After exploring sampling distributions, the authors discuss point estimation, confidence intervals, hypothesis testing, and a wide range of nonparametric methods. With a focus on experimental design, the book also presents fixed- and random-effects models as well as randomized block and two-factor factorial designs. The final chapter describes simple and multiple regression analyses. Demonstrating that R can be used as a powerful teaching aid, this comprehensive text presents extensive treatments of data analysis using parametric and nonparametric techniques. It effectively links statistical concepts with R procedures, enabling the application of the language to the vast world of statistics.

Haschek and Rousseaux s Handbook of Toxicologic Pathology

Author: Wanda M. Haschek
Publisher: Academic Press
ISBN: 0124157653
Format: PDF
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Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

The Analysis of Time Series

Author: Chris Chatfield
Publisher: CRC Press
ISBN: 9780203491683
Format: PDF
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Since 1975, The Analysis of Time Series: An Introduction has introduced legions of statistics students and researchers to the theory and practice of time series analysis. With each successive edition, bestselling author Chris Chatfield has honed and refined his presentation, updated the material to reflect advances in the field, and presented interesting new data sets. The sixth edition is no exception. It provides an accessible, comprehensive introduction to the theory and practice of time series analysis. The treatment covers a wide range of topics, including ARIMA probability models, forecasting methods, spectral analysis, linear systems, state-space models, and the Kalman filter. It also addresses nonlinear, multivariate, and long-memory models. The author has carefully updated each chapter, added new discussions, incorporated new datasets, and made those datasets available for download from www.crcpress.com. A free online appendix on time series analysis using R can be accessed at http://people.bath.ac.uk/mascc/TSA.usingR.doc. Highlights of the Sixth Edition: A new section on handling real data New discussion on prediction intervals A completely revised and restructured chapter on more advanced topics, with new material on the aggregation of time series, analyzing time series in finance, and discrete-valued time series A new chapter of examples and practical advice Thorough updates and revisions throughout the text that reflect recent developments and dramatic changes in computing practices over the last few years The analysis of time series can be a difficult topic, but as this book has demonstrated for two-and-a-half decades, it does not have to be daunting. The accessibility, polished presentation, and broad coverage of The Analysis of Time Series make it simply the best introduction to the subject available.

Statistik Workshop f r Programmierer

Author: Allen B. Downey
Publisher: O'Reilly Germany
ISBN: 3868993436
Format: PDF
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Wenn Sie programmieren können, beherrschen Sie bereits Techniken, um aus Daten Wissen zu extrahieren. Diese kompakte Einführung in die Statistik zeigt Ihnen, wie Sie rechnergestützt, anstatt auf mathematischem Weg Datenanalysen mit Python durchführen können. Praktischer Programmier-Workshop statt grauer Theorie: Das Buch führt Sie anhand eines durchgängigen Fallbeispiels durch eine vollständige Datenanalyse -- von der Datensammlung über die Berechnung statistischer Kennwerte und Identifikation von Mustern bis hin zum Testen statistischer Hypothesen. Gleichzeitig werden Sie mit statistischen Verteilungen, den Regeln der Wahrscheinlichkeitsrechnung, Visualisierungsmöglichkeiten und vielen anderen Arbeitstechniken und Konzepten vertraut gemacht. Statistik-Konzepte zum Ausprobieren: Entwickeln Sie über das Schreiben und Testen von Code ein Verständnis für die Grundlagen von Wahrscheinlichkeitsrechnung und Statistik: Überprüfen Sie das Verhalten statistischer Merkmale durch Zufallsexperimente, zum Beispiel indem Sie Stichproben aus unterschiedlichen Verteilungen ziehen. Nutzen Sie Simulationen, um Konzepte zu verstehen, die auf mathematischem Weg nur schwer zugänglich sind. Lernen Sie etwas über Themen, die in Einführungen üblicherweise nicht vermittelt werden, beispielsweise über die Bayessche Schätzung. Nutzen Sie Python zur Bereinigung und Aufbereitung von Rohdaten aus nahezu beliebigen Quellen. Beantworten Sie mit den Mitteln der Inferenzstatistik Fragestellungen zu realen Daten.