Ethical Challenges in Genomics Research

Author: Paula Boddington
Publisher: Springer Science & Business Media
ISBN: 3642236995
Format: PDF, Mobi
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New developments in science and technology have resulted in shifting ethical challenges in many areas including in genomics research. This book enables those who are involved in genomics research, whether as researcher, participant or policy maker, to understand the ethical issues currently developing in this field and to participate actively in these important debates. A clear account is given of how science and technology are outstripping the capacity of previous ethical regulations to cope with current issues, together with practical illustrations of possible ways forward. Key ethical ideas are presented, drawing on the history of research regulation and on an account of the particular challenges arising in the field of genomics. The book uses a grounded, practical approach to explaining ethical concepts and issues which is geared to enhancing interdisciplinary dialogue. Its broad approach to ethical issues includes relevant considerations from social psychology and there is a particular emphasis on understanding the problems of ethical regulations and practice in the institutional and social context of research. A glossary and numerous text boxes explaining relevant terms and key ideas help to make the work an invaluable resource for both beginners and experts in the field.

Personalized Evolutionary and Ecological Dermatology

Author: Robert A. Norman
Publisher: Springer
ISBN: 3319410881
Format: PDF, Kindle
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This book discusses the exciting potential for dermatology to embrace developments to enhance the profession’s valuable pattern recognition, diagnostic, and treatment skills. Personalized medicine (PM) and genomics are easily accessible and enable the customization of healthcare using molecular analysis to influence medical decisions, practices, and therapies for the individual patient. The evolution of the skin, and the manner in which dermatological conditions are described and managed, reveals the need to consider many aspects on a personal level. New research data are based on the use of evolutionary medicine and genomics to highlight how we can become more successful at finding the most efficacious types of antibiotic or therapy and dosage for a particular disease or pathogen and build a competitive edge by prevention and risk management against invasive viruses, bacteria, or wrongly administered drugs. As more is understood about what grows on us and how it all interacts, along with how the introduction of new antibiotics, biologics, and other therapies affect our skin’s ecological balance, this book aims to create a heightened sense of the importance and offerings of ecological dermatology.

Ethical Issues in Clinical Research

Author: Bernard Lo
Publisher: Lippincott Williams & Wilkins
ISBN: 1451152779
Format: PDF, Kindle
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This book teaches researchers how to resolve the ethical dilemmas that can arise at any stage in clinical research. In addition to explaining pertinent regulations and laws, Dr. Lo helps investigators understand the gaps and uncertainties in regulations, as well as situations in which merely complying with the law may not fulfill ethical responsibilities. Most chapters include real-life examples that the author walks through, discussing the salient issues and how to approach them. This book can be used in courses on research ethics that are required or encouraged by major National Institutes of Health grants in academic health centers.

Research Ethics in Africa

Author: Mariana Kruger
Publisher: AFRICAN SUN MeDIA
ISBN: 1920689303
Format: PDF, ePub
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The aim of this book is to provide research ethics committee members with a resource that focuses on research ethics issues in Africa. The authors are currently active in various aspects of research ethics in Africa and the majority have been trained in the past by either the Fogarty International Center or Europe and Developing Countries Clinical Trial Partnership (EDCTP) sponsored bioethics training programmes .

Ethical Issues of Human Genetic Databases

Author: Bernice Elger
Publisher: Routledge
ISBN: 1317141466
Format: PDF, Mobi
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Following the boom in population databases in recent years there has been sustained and intense international debate about political processes and legal and ethical issues surrounding the protection and use of genetic data. As a result, several national and international organizations and committees have published widely differing guidelines and statements concerning genetic databases and biobanks. Ethical Issues of Human Genetic Databases compares the new area of biobanking with the tradition of ethically accepted classical research and highlights the distinctive features of existing databases and guidelines. The volume identifies areas of consensus and controversy while investigating the challenges posed to classical health research ethics by the existence of genetic databases, analyzing the reasons for such varying guidelines. The book will be essential to academics, biobankers, policy-makers and researchers in the field of medical ethics.

Ethics of Emerging Technologies

Author: Thomas F. Budinger
Publisher: Wiley
ISBN:
Format: PDF, Kindle
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An insightful guide to understanding and navigating the ethical issues faced by anyone affected by the ethical dilemmas associated with current and emerging technologies Ethics of Emerging Technologies provides the background, insight, and tools for approaching and solving ethical dilemmas across a broad range of topics. The text discusses ethical problems, using examples and reasoning tools that will aid engineers, scientists, managers, administrators, and the public who wish to understand risks, benefits, and possible approaches to resolving conflicts associated with new technologies in the context of the global community. Solutions we choose to ethical dilemmas accompanying new technologies will profoundly affect future generations. Scientific facts and guides to decision-making for all associated with emerging technologies are presented. Some of the topics are: * Human health and environmental effects of alternative energy production methods * Communications and privacy * Plagiarism and authorship * Genetic modification of organisms * Human and animal experimentation * Synthetic biology and bioterrorism * Confidentiality in science, engineering, and business communications * Risks and consequences of enhancing human beings through new technologies * Cloning of human beings and stem cell research * Brain modifications * Space exploration

Human Genome Editing

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452880
Format: PDF, ePub, Mobi
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Genome editing is a powerful new tool for making precise alterations to an organism’s genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Ethical Issues of Human Genetic Databases

Author: Bernice Elger
Publisher: Routledge
ISBN: 1317141466
Format: PDF, ePub
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Following the boom in population databases in recent years there has been sustained and intense international debate about political processes and legal and ethical issues surrounding the protection and use of genetic data. As a result, several national and international organizations and committees have published widely differing guidelines and statements concerning genetic databases and biobanks. Ethical Issues of Human Genetic Databases compares the new area of biobanking with the tradition of ethically accepted classical research and highlights the distinctive features of existing databases and guidelines. The volume identifies areas of consensus and controversy while investigating the challenges posed to classical health research ethics by the existence of genetic databases, analyzing the reasons for such varying guidelines. The book will be essential to academics, biobankers, policy-makers and researchers in the field of medical ethics.

Ethics Computing and Genomics

Author: Herman T. Tavani
Publisher: Jones & Bartlett Learning
ISBN: 9780763736200
Format: PDF, Kindle
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Comprised of eighteen chapters contributed by experts in the fields of biology, computer science, information technology, law, and philosophy, Ethics, Computing, and Genomics provides instructors with a flexible resource for undergraduate and graduate courses in an exciting new field of applied ethics: computational genomics. The chapters are organized in a way that takes the reader from a discussion of conceptual frameworks and methodological perspectives, including ethical theory, to an in-depth analysis of controversial issues involving privacy and confidentiality, information consent, and intellectual property. The volume concludes with some predictions about the future of computational genomics, including the role that nanotechnology will likely play as biotechnologies and information technologies continue to converge.

Ethical Dilemmas in Genetics and Genetic Counseling

Author: Janice Berliner MS, CGC
Publisher: Oxford University Press
ISBN: 0190206640
Format: PDF, ePub, Mobi
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Knowledge of the genetic basis of human diseases is growing rapidly, with important implications for pre-conceptional, prenatal, and predictive testing. While new genetic testing offers better insight into the causes of and susceptibility for heritable diseases, not all inherited diseases that can be predicted on the basis of genetic information can be treated or cured. Should we test everyone who wants to know his or her genetic status, even when there are no possibilities for treatment? What is the role of the "right-not-to-know?" Do we test children for adult onset disorders because the parents just "have to know" or do we respect the children's right to choose when they are older? Do we allow commercial companies to offer genetic tests directly to consumers without the proper oversight regarding what the test results will mean? By using a creative approach that focuses on a single extended family as a case example to illustrate each chapter's key point, the authors elucidate ethical issues arising in the genetics clinic and laboratory surrounding many timely issues, including: ? prenatal and pre-implantation genetic diagnosis ? assisted reproductive technologies ? incidental findings in genetic testing ? gene patenting ? testing children for adult onset disorders ? direct to consumer testing Ethical Dilemmas in Genetic Counseling: Principles through Case Scenarios is essential reading for anyone interested in the ethical issues surfacing in common genetics practice. Written exclusively by genetic counselors, it makes a significant contribution to the field of ethics in genetics and thus will appeal not only to genetic counselors but to physicians, nurses, and all those concerned with bioethics and social science.