From Computer to Brain

Author: William W. Lytton
Publisher: Springer Science & Business Media
ISBN: 0387227334
Format: PDF, ePub
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Biology undergraduates, medical students and life-science graduate students often have limited mathematical skills. Similarly, physics, math and engineering students have little patience for the detailed facts that make up much of biological knowledge. Teaching computational neuroscience as an integrated discipline requires that both groups be brought forward onto common ground. This book does this by making ancillary material available in an appendix and providing basic explanations without becoming bogged down in unnecessary details. The book will be suitable for undergraduates and beginning graduate students taking a computational neuroscience course and also to anyone with an interest in the uses of the computer in modeling the nervous system.

Fundamentals of Computational Neuroscience

Author: Thomas Trappenberg
Publisher: Oxford University Press
ISBN: 0199568413
Format: PDF, Docs
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The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. It introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain. The book covers the introduction and motivation of simplified models of neurons that are suitable for exploring information processing in large brain-like networks. Additionally, it introduces several fundamental networkarchitectures and discusses their relevance for information processing in the brain, giving some examples of models of higher-order cognitive functions to demonstrate the advanced insight that can begained with such studies.

Computational Neuroscience

Author: Eric L. Schwartz
Publisher: MIT Press
ISBN: 9780262691642
Format: PDF, Mobi
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The thirty original contributions in this book provide a working definition of"computational neuroscience" as the area in which problems lie simultaneously within computerscience and neuroscience. They review this emerging field in historical and philosophical overviewsand in stimulating summaries of recent results. Leading researchers address the structure of thebrain and the computational problems associated with describing and understanding this structure atthe synaptic, neural, map, and system levels.The overview chapters discuss the early days of thefield, provide a philosophical analysis of the problems associated with confusion between brainmetaphor and brain theory, and take up the scope and structure of computationalneuroscience.Synaptic-level structure is addressed in chapters that relate the properties ofdendritic branches, spines, and synapses to the biophysics of computation and provide a connectionbetween real neuron architectures and neural network simulations.The network-level chapters take upthe preattentive perception of 3-D forms, oscillation in neural networks, the neurobiologicalsignificance of new learning models, and the analysis of neural assemblies and local learningrides.Map-level structure is explored in chapters on the bat echolocation system, cat orientationmaps, primate stereo vision cortical cognitive maps, dynamic remapping in primate visual cortex, andcomputer-aided reconstruction of topographic and columnar maps in primates.The system-level chaptersfocus on the oculomotor system VLSI models of early vision, schemas for high-level vision,goal-directed movements, modular learning, effects of applied electric current fields on corticalneural activity neuropsychological studies of brain and mind, and an information-theoretic view ofanalog representation in striate cortex.Eric L. Schwartz is Professor of Brain Research and ResearchProfessor of Computer Science, Courant Institute of Mathematical Sciences, New York UniversityMedical Center. Computational Neuroscience is included in the System Development FoundationBenchmark Series.

Principles of Computational Modelling in Neuroscience

Author: David Sterratt
Publisher: Cambridge University Press
ISBN: 1139500791
Format: PDF
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The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.

Graphical Models

Author: Michael Irwin Jordan
Publisher: MIT Press
ISBN: 9780262600422
Format: PDF
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This book exemplifies the interplay between the general formal framework of graphical models and the exploration of new algorithm and architectures. The selections range from foundational papers of historical importance to results at the cutting edge of research. Graphical models use graphs to represent and manipulate joint probability distributions. They have their roots in artificial intelligence, statistics, and neural networks. The clean mathematical formalism of the graphical models framework makes it possible to understand a wide variety of network-based approaches to computation, and in particular to understand many neural network algorithms and architectures as instances of a broader probabilistic methodology. It also makes it possible to identify novel features of neural network algorithms and architectures and to extend them to more general graphical models.This book exemplifies the interplay between the general formal framework of graphical models and the exploration of new algorithms and architectures. The selections range from foundational papers of historical importance to results at the cutting edge of research. Contributors H. Attias, C. M. Bishop, B. J. Frey, Z. Ghahramani, D. Heckerman, G. E. Hinton, R. Hofmann, R. A. Jacobs, Michael I. Jordan, H. J. Kappen, A. Krogh, R. Neal, S. K. Riis, F. B. Rodríguez, L. K. Saul, Terrence J. Sejnowski, P. Smyth, M. E. Tipping, V. Tresp, Y. Weiss

Handbook of Brain Microcircuits

Author: Gordon M. Shepherd
Publisher: Oxford University Press
ISBN: 0190636114
Format: PDF, Mobi
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Updated and revised, the second edition of Handbook of Brain Microcircuits covers the functional organization of 50 brain regions. This now-classic text uses an interdisciplinary approach to examine the integration of structure, function, electrophysiology, pharmacology, brain imaging, and behavior. Through uniquely concise and authoritative chapters by leaders in their fields, the Handbook of Brain Microcircuits synthesizes many of the new principles of microcircuit organization that are defining a new era in understanding the brain connectome, integrating the major neuronal pathways and essential microcircuits with brain function. New to the Second Edition: � Insights into new regions of the brain through canonical microcircuit diagrams for each region � Latest methodology in optogenetics, neurotransmitter uncaging, computational models of neurons and microcircuits, serial ultrastructure reconstructions, cellular and regional imaging � Extrapolated data from new genetic tools and understandings applied to microcircuits in the mouse and Drosophila � Common principles across vertebrate and invertebrate microcircuit systems, one of the key goals of modern neuroscience

Mathematical Foundations of Neuroscience

Author: G. Bard Ermentrout
Publisher: Springer Science & Business Media
ISBN: 0387877088
Format: PDF
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This book applies methods from nonlinear dynamics to problems in neuroscience. It uses modern mathematical approaches to understand patterns of neuronal activity seen in experiments and models of neuronal behavior. The intended audience is researchers interested in applying mathematics to important problems in neuroscience, and neuroscientists who would like to understand how to create models, as well as the mathematical and computational methods for analyzing them. The authors take a very broad approach and use many different methods to solve and understand complex models of neurons and circuits. They explain and combine numerical, analytical, dynamical systems and perturbation methods to produce a modern approach to the types of model equations that arise in neuroscience. There are extensive chapters on the role of noise, multiple time scales and spatial interactions in generating complex activity patterns found in experiments. The early chapters require little more than basic calculus and some elementary differential equations and can form the core of a computational neuroscience course. Later chapters can be used as a basis for a graduate class and as a source for current research in mathematical neuroscience. The book contains a large number of illustrations, chapter summaries and hundreds of exercises which are motivated by issues that arise in biology, and involve both computation and analysis. Bard Ermentrout is Professor of Computational Biology and Professor of Mathematics at the University of Pittsburgh. David Terman is Professor of Mathematics at the Ohio State University.

Computational Neuroscience and Cognitive Modelling

Author: Britt Anderson
Publisher: SAGE
ISBN: 1446297373
Format: PDF, ePub
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"For the neuroscientist or psychologist who cringes at the sight of mathematical formulae and whose eyes glaze over at terms like differential equations, linear algebra, vectors, matrices, Bayes’ rule, and Boolean logic, this book just might be the therapy needed." - Anjan Chatterjee, Professor of Neurology, University of Pennsylvania "Anderson provides a gentle introduction to computational aspects of psychological science, managing to respect the reader’s intelligence while also being completely unintimidating. Using carefully-selected computational demonstrations, he guides students through a wide array of important approaches and tools, with little in the way of prerequisites...I recommend it with enthusiasm." - Asohan Amarasingham, The City University of New York This unique, self-contained and accessible textbook provides an introduction to computational modelling neuroscience accessible to readers with little or no background in computing or mathematics. Organized into thematic sections, the book spans from modelling integrate and firing neurons to playing the game Rock, Paper, Scissors in ACT-R. This non-technical guide shows how basic knowledge and modern computers can be combined for interesting simulations, progressing from early exercises utilizing spreadsheets, to simple programs in Python. Key Features include: Interleaved chapters that show how traditional computing constructs are simply disguised versions of the spread sheet methods. Mathematical facts and notation needed to understand the modelling methods are presented at their most basic and are interleaved with biographical and historical notes for contex. Numerous worked examples to demonstrate the themes and procedures of cognitive modelling. An excellent text for postgraduate students taking courses in research methods, computational neuroscience, computational modelling, cognitive science and neuroscience. It will be especially valuable to psychology students.

The Computational Brain

Author: Patricia S. Churchland
Publisher: MIT Press
ISBN: 0262533391
Format: PDF, ePub, Docs
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An anniversary edition of the classic work that influenced a generation of neuroscientists and cognitive neuroscientists.

Computational Vision

Author: Hanspeter A. Mallot
Publisher: MIT Press
ISBN: 9780262133814
Format: PDF, ePub, Docs
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This text provides an introduction to computational aspects of early vision, in particular, color, stereo, and visual navigation. It integrates approaches from psychophysics and quantitative neurobiology, as well as theories and algorithms from machine vision and photogrammetry. When presenting mathematical material, it uses detailed verbal descriptions and illustrations to clarify complex points. The text is suitable for upper-level students in neuroscience, biology, and psychology who have basic mathematical skills and are interested in studying the mathematical modeling of perception.