Functional Biochemistry in Health and Disease

Author: Eric Newsholme
Publisher: John Wiley & Sons
ISBN: 1119965241
Format: PDF, ePub, Docs
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Functional Biochemistry in Health and Disease provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice. Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, relevant diagrams enhance students' understanding. Focuses on medically relevant aspects of biochemistry written from a physiological rather than a chemical perspective. Clear presentation that minimises the use of jargon. Each chapter contains boxes on related topics, relevant diagrams and a brief glossary. Coverage includes athletic performance, apoptosis and the immune system. Key historical developments are included to show how modern biochemistry has evolved. By linking biochemistry, medical education and clinical practice this book will prove invaluable to students in medical and health sciences, biomedical science and human biology taking an introductory biochemistry course. In addition it will appeal to biochemistry and biology students interested in clinical applications of biochemistry.

Functional Biochemistry in Health and Disease

Author: Eric Newsholme
Publisher: Wiley
ISBN: 9780471931652
Format: PDF, ePub
Download Now
Functional Biochemistry in Health and Disease provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice. Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, relevant diagrams enhance students' understanding. Focuses on medically relevant aspects of biochemistry written from a physiological rather than a chemical perspective. Clear presentation that minimises the use of jargon. Each chapter contains boxes on related topics, relevant diagrams and a brief glossary. Coverage includes athletic performance, apoptosis and the immune system. Key historical developments are included to show how modern biochemistry has evolved. By linking biochemistry, medical education and clinical practice this book will prove invaluable to students in medical and health sciences, biomedical science and human biology taking an introductory biochemistry course. In addition it will appeal to biochemistry and biology students interested in clinical applications of biochemistry.

Functional Biochemistry in Health and Disease

Author: Eric Newsholme
Publisher: LibreDigital
ISBN: 9780471931652
Format: PDF, Docs
Download Now
Functional Biochemistry in Health and Disease provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice. Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, relevant diagrams enhance students’ understanding. Focuses on medically relevant aspects of biochemistry written from a physiological rather than a chemical perspective. Clear presentation that minimises the use of jargon. Each chapter contains boxes on related topics, relevant diagrams and a brief glossary. Coverage includes athletic performance, apoptosis and the immune system. Key historical developments are included to show how modern biochemistry has evolved. Companion website By linking biochemistry, medical education and clinical practice this book will prove invaluable to students in medical and health sciences, biomedical science and human biology taking an introductory biochemistry course. In addition it will appeal to biochemistry and biology students interested in clinical applications of biochemistry. There is a companion website which can be found at wwwe.wiley.com/go/newsholme/ciochemistry. This features numerous appendices which contain useful background material.

Biochemical Imbalances in Disease

Author: Ann Woodriff Beirne
Publisher: Singing Dragon
ISBN: 9780857010285
Format: PDF, Mobi
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Biochemical imbalances caused by nutritional deficiencies are a contributory factor in chronic illnesses such as cardiovascular disease, diabetes, auto-immune conditions and cancer. This handbook for practitioners explains how to identify and treat such biochemical imbalances in order to better understand and manage a patient's ill-health. The book examines a range of biochemical imbalances, including compromised adrenal or thyroid function, gastro-intestinal imbalances, immune system problems and sex hormone imbalances, and explains how and why such states occur. It pulls together a wide range of evidence to show how such imbalances are involved in the most common chronic diseases. It helps practitioners to understand how to identify the imbalances through appropriate case history taking and laboratory testing, and how to design and implement effective nutritional interventions. Developed by leading academics and practitioners in the fields of nutritional therapy and functional medicine, this evidence-informed approach can be used with all patients who present in clinic, regardless of whether or not they have a 'named medical condition'. In the final chapter, a case example illustrates how to use the theoretical information in the practice of treating patients with chronically compromised health. Biochemical Imbalances in Disease is an essential text for nutritional therapy practitioners, as well as for students, and will be welcomed by complementary and conventional healthcare practitioners alike.

Biochemistry for the Medical Sciences

Author: Eric Newsholme
Publisher: Wiley
ISBN: 9780471900580
Format: PDF, Kindle
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This outstanding text, written in a clear, concise and easy-to-read style, provides students with an in-depth explanation of how each metabolic pathway is directly related to physiology, pharmacology, and clinical medicine. Emphasis is given to those medical problems encountered most frequently in daily clinical practice. Basic metabolism is presented as a coherent part of physiology and reference is made to the matabaolic aberrations seen in clinical situations.

Glutathione and Sulfur Amino Acids in Human Health and Disease

Author: Roberta Masella
Publisher: John Wiley & Sons
ISBN: 9780470475966
Format: PDF, Docs
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The complex roles of glutathione and sulfur amino acids in human health Glutathione (γ-L-glutamyl-L-cysteinylglycine, GSH) is a major antioxidant acting as a free radical scavenger that protects the cell from reactive oxygen species (ROS). Sulfur amino acids (SAAs), such as methionine and cysteine, play a critical role in the maintenance of health. GSH depletion as well as alterations of SAA metabolism are linked to a host of disease states including liver cirrhosis, various pulmonary diseases, myocardial ischemia and reperfusion injury, aging, Parkinson's disease, Alzheimer's disease, sepsis, and others. This book provides researchers with a comprehensive review of the biochemistry, absorption, metabolism, biological activities, disease prevention, and health promotion of glutathione and sulfur amino acids. The twenty-two chapters explore such topics as: Chemistry, absorption, transport, and metabolism of GSH and sulfur amino acids Antioxidant and detoxification properties of GSH and sulfur amino acids, highlighting the enzymatic systems involved in antioxidant defenses Biological activities of GSH and sulfur amino acids and their role in modulating cell processes Role of GSH and sulfur amino acid deficiency and alteration in the onset of diseases and in aging Protective effects exerted by GSH and sulfur amino acids when used as drugs, functional foods, and nutraceuticals in humans and animals Special attention is paid to the molecular mechanisms for the modulation of transcription factors and enzyme activities, as well as the nutritional and therapeutic significance of dietary sulfur amino acids as shown in human and animal models. With more than 2,000 scientific references, this book provides food scientists, nutritionists, biochemists, food technologists, chemists, molecular biologists, and public health professionals with a comprehensive and up-to-date examination of glutathione and sulfur amino acids in human health and disease.

Functional Metabolism

Author: Kenneth B. Storey
Publisher: John Wiley & Sons
ISBN: 9780471675570
Format: PDF, ePub, Docs
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Functional Metabolism of Cells is the first comprehensive survey of metabolism, offering an in-depth examination of metabolism and regulation of carbohydrates, lipids, and amino acids. It provides a basic background on metabolic regulation and adaptation as well as the chemical logic of metabolism, and covers the interrelationship of metabolism to life processes of the whole organism. The book lays out a structured approach to the metabolic basis of disease, including discussion of the normal pathways of metabolism, altered pathways leading to disease, and use of molecular genetics in diagnosis and treatment of disease. It also takes a unique comparative approach in which human metabolism is a reference for metabolism in microorganisms and plant design, and presents novel coverage of development and aging, and human health and animal adaptation. The final chapter reviews the past and future promise of new genetic approaches to treatment and bioinformatics. This, the most exhaustive treatment of metabolism currently available, is a useful text for advanced undergraduates and graduates in biochemistry, cell/molecular biology, and biomedicine, as well as biochemistry instructors and investigators in related fields.

Adipose Tissue in Health and Disease

Author: Todd Leff
Publisher: John Wiley & Sons
ISBN: 9783527629534
Format: PDF, ePub, Docs
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This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.

Plant Phenolics and Human Health

Author: IUBMB
Publisher: John Wiley & Sons
ISBN: 0470531789
Format: PDF
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A collection of current knowledge of phytochemicals and health Interest in phenolic phytochemicals has increased as scientific studies indicate these compounds exhibit potential health benefits. With contributions from world leaders in this research area, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology offers an essential survey of the current knowledge on the capacity of specific micronutrients present in ordinary diets to fight disease. The coverage in this resource: Explains the presence and biochemical properties of phenolics present in fruits and vegetables, as well as in foods derived from their plant sources Provides biochemical explanations on how certain plant phenolics fight cardiovascular and neurodegenerative diseases, cancer, and other widespread pathologies Focuses on certain phenolics, e.g., flavonoids, stilbenes, and curcuminoids, and provides insights on the biochemical bases used to define their significance in the diet as well as their recommended consumption requirements and toxicity Appropriate for graduate and upper-level undergraduate courses in human and animal nutrition, basic nutritional biology, physiology, pharmacology, and other health-related disciplines, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology serves as both an invaluable supplementary classroom text and a self-teaching guide for professionals interested in defining the association between diet and health from classical, alternative, and complementary biomedical perspectives.

Brain Biochemistry and Brain Disorders

Author: Philip Gordon Strange
Publisher: Oxford University Press, USA
ISBN: 9780198542599
Format: PDF, Docs
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One of the major challenges facing science is understanding the relationship between the structure of the brain and the functions it generates, and in particular how this function can be disturbed in brain disorders. This book addresses this challenge by describing the brain at the neuroanatomical, cellular, and subcellular levels, and analyzing how the cellular components are assembled into functional arrays. This leads to a discussion of the concept of mind, and modern theories of mind based on the function of neurons. The final part of the book considers disorders of the brain, looking in detail at Parkinson's disease, Alzheimer's disease, Huntington's disease, schizophrenia, depression and anxiety. In each case, emphasis is placed on the relationship between changes in the brain at the biochemical level and changes in function at the behavioral and psychological level. By bridging the gap between basic and clinical sciences, this book provides a new perspective on brain function and brain disorders. It explains key concepts clearly, giving students of neuroscience and related subjects a thorough introduction to this key topic, and a foundation for future study. It is also a concise review and reference text for researchers.