Functional Biochemistry in Health and Disease

Author: Eric Newsholme
Publisher: John Wiley & Sons
ISBN: 1119965241
Format: PDF, Kindle
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Functional Biochemistry in Health and Disease provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice. Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, relevant diagrams enhance students' understanding. Focuses on medically relevant aspects of biochemistry written from a physiological rather than a chemical perspective. Clear presentation that minimises the use of jargon. Each chapter contains boxes on related topics, relevant diagrams and a brief glossary. Coverage includes athletic performance, apoptosis and the immune system. Key historical developments are included to show how modern biochemistry has evolved. By linking biochemistry, medical education and clinical practice this book will prove invaluable to students in medical and health sciences, biomedical science and human biology taking an introductory biochemistry course. In addition it will appeal to biochemistry and biology students interested in clinical applications of biochemistry.

Foundations and Applications of Medical Biochemistry in Clinical Practice

Author: John Neustadt Nd
Publisher: iUniverse
ISBN: 9781440125348
Format: PDF, Docs
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The culmination of more than ten years of research by the authors, this book describes for the first time ever the scientific basis and clinical applications of medical biochemistry, a fundamental paradigm shift in medicine. This paradigm shift is so revolutionary that it has been called the Neustadt-Pieczenik Paradigm, which is the fusion and clinical applications of biochemistry, thermodynamics, physiology, fractal enzymology, nutritional medicine and laboratory testing to identify and correct the underlying causes of many diseases that are considered genetic in nature (eg, Phenylketonuria) and those that are not considered genetic (eg, mature onset asthma, depression, fatigue). In this new medicine, doctors must reject the failed, purely symptomatic treatments they learned in medical school and focus on learning and treating the underlying biochemical causes of disease. From the first documented clinical observations of biochemical individuality in the early 1900s to the development of sophisticated biochemical tests, the authors provide a detailed and stunning analysis of a new medical model to help millions and cure our ailing healthcare system. They uniquely contrast the conventional medical approach with the functional biochemical approach through extensive case studies on depression, arthritis, migraine headaches, seizures, rashes and more. This book is a must-read for physicians, medical students, nutritionists, and anyone looking to take charge of their health.

Clinical Studies in Medical Biochemistry

Author: Robert H. Glew
Publisher: Oxford University Press
ISBN: 9780199749096
Format: PDF, Mobi
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This text uses a case-study approach to present core principles of biochemistry and molecular biology in the context of human disease. The thirty-three cases have been carefully chosen to cover key concepts and common diseases. Each chapter provides a specific patient report that includes relevant history, pertinent clinical laboratory data, physical findings, and subsequent diagnosis. This is followed by a comprehensive discussion of normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. In this third edition of the book, a new co-editor has aided in the substantially revised and more targeted selection of cases. The whole volume is now clearly focused on intermediary metabolism and other topics central to biochemistry. There are new chapters on topics such as collagen structure, mitochondrial metabolism, and hyperhomocysteinemia and vascular disease. There is also more coverage of nutritional biochemistry, including new chapters on protein-calorie malnutrition, obesity, vitamin A deficiency, and iron metabolism. The best cases were retained from the previous edition, and have been completely rewritten and updated to include recent advances in diagnostic biochemistry and the status of current therapies. Although the first edition was intended primarily for medical students, through the years the book has proven useful for a wide variety of students interested in the health science professions.

Principles of Medical Biochemistry E Book

Author: Gerhard Meisenberg
Publisher: Elsevier Health Sciences
ISBN: 032308107X
Format: PDF, ePub, Docs
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Principles of Medical Biochemistry condenses the information you need into a comprehensive, focused, clinically-oriented textbook. Drs. Gerhard Meisenberg and William H. Simmons covers the latest developments in the field, including genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, and more. An updated and expanded collection of figures and access to USMLE test questions, clinical case studies, more online at www.studentconsult.com make this the ideal resource for understanding all aspects of biochemistry needed in medicine. Access the complete contents online at www.studentconsult.com, with downloadable illustrations, 150 USMLE-style test questions, 20 clinical case studies, chapter summaries, and integration links to related subjects. Understand biochemistry, cell biology, and genetics together in context through an integrated approach. Get only the information you need for your course with comprehensive yet focused coverage of relevant topics. Review and reinforce your learning using the glossary of technical terms, highlighted in the text and with interactive features online. Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more. Gain a clear visual understanding through new and updated figures that provide current and relevant guidance. Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter.

Brain Biochemistry and Brain Disorders

Author: Philip Gordon Strange
Publisher: Oxford University Press, USA
ISBN: 9780198542599
Format: PDF
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One of the major challenges facing science is understanding the relationship between the structure of the brain and the functions it generates, and in particular how this function can be disturbed in brain disorders. This book addresses this challenge by describing the brain at the neuroanatomical, cellular, and subcellular levels, and analyzing how the cellular components are assembled into functional arrays. This leads to a discussion of the concept of mind, and modern theories of mind based on the function of neurons. The final part of the book considers disorders of the brain, looking in detail at Parkinson's disease, Alzheimer's disease, Huntington's disease, schizophrenia, depression and anxiety. In each case, emphasis is placed on the relationship between changes in the brain at the biochemical level and changes in function at the behavioral and psychological level. By bridging the gap between basic and clinical sciences, this book provides a new perspective on brain function and brain disorders. It explains key concepts clearly, giving students of neuroscience and related subjects a thorough introduction to this key topic, and a foundation for future study. It is also a concise review and reference text for researchers.

Parkinson s Disease Dopamine Metabolism Applied Biochemistry and Nutrition

Author: Lucille Leader
Publisher:
ISBN: 9780952605669
Format: PDF, Docs
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PARKINSON S DISEASE DOPAMINE METABOLISM, APPLIED BIOCHEMISTRY & NUTRITION Authors: Lucille Leader and Dr Geoffrey Leader Foreword: by Dr Nicholas Miller This user-friendly monograph illustrates the various metabolic pathways implicated in Parkinson s disease, with their primary sources in protein, carbohydrates and fats. It describes the enzymes necessary for metabolic and biochemical progress with their dependence on coenzymes - which are specific nutrients. The text demonstrates that concomitant with dopaminergic pharmaceutical supplementation, dynamic support of the individual s biochemical, metabolic and nutritional status should be considered as essential adjuvant therapy during the degenerative journey. The aim is to optimise potential cellular and general functional health within the constraints of the disease. Dopamine, the neurotransmitter which is deficient in Parkinson s disease, is metabolised from dietary protein. The metabolic steps from protein ingestion in the diet to the production of dopamine in the brain - and further on to adrenaline, are best described by biochemistry. Contemporary nutritional management is the APPLICATION of biochemical principles. Medical tests as well as state of the art nutritional biochemical tests are presented which enable the medical and nutritional professions to up- or down- regulate the individual cellular environment. Subjects presented include: dopamine metabolism adrenal metabolism inflammation and prostaglandins oxidative stress and free radicals

A Revolution in Health Through Nutritional Biochemistry

Author: John Neustadt
Publisher:
ISBN: 9780595453405
Format: PDF, ePub, Mobi
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Biochemical testing is a revolutionary concept in medicine that has saved many lives and improved the health of countless others. Symptoms and diseases have underlying biochemical causes, and advanced testing technologies can now detect the exact steps within pathways causing diseases, including depression, fatigue, adult-onset asthma, seizure disorders, multiple sclerosis, osteoporosis, diabetes, metabolic syndrome, irritable bowel syndrome, memory loss, and more. Biochemical abnormalities may then be corrected using targeted nutrient therapies. Nutritional Biochemistry is a revolutionary approach that is redefining medicine and providing clinicians the ability treat the underlying causes of disease instead of just ameliorating symptoms with drugs. "The principles set out in this book are at the same time both ancient and revolutionary. Ancient because they have been known and followed for thousands of years, but revolutionary in our time because they run counter to the approach to health with which all of us have grown up. The principles are simple: 1) most medical approaches treat symptoms not causes; 2) most pharmaceuticals and medicines are intended to destroy something, not add something; 3) with our modern lives and diet, most people are lacking one or more things essential to the proper functioning of the body and need to add them, both to eliminate existing problems and to maintain optimum health. These principles are always a supplement, sometimes an alternative, to conventional medicine. I cite my own successful experience that they work when conventional treatments have not done so." -John W. Hanes, Jr. Former Director, Squibb Corp.

Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition

Author: Lynnette R. Ferguson
Publisher: CRC Press
ISBN: 1439876819
Format: PDF, Docs
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While functional foods have become a reasonably well-established concept, personalized nutrition is still treated with skepticism by many. The recognition that people would have different nutrient requirements, or perceive foods in different ways, raises several concerns—some real, some not so real. Nutrigenomics and Nutrigenetics in Functional Foods and Personalized Nutrition addresses what is needed to bring nutrigenomics, nutrigenetics, and their associated technologies to market in a truly impactful way. Edited by Lynnette R. Ferguson, a well-known and internationally respected researcher, the book covers a wide range of issues, from the purely scientific to ethical, consumer-driven, and public health aspects. It takes a close look at gene–diet interactions and explores the ways in which studies on nutrigenomics and nutrigenetics can help modulate disease risk in cardiovascular disease, obesity, diabetes, and inflammatory bowel disease. Topics include regulatory challenges, genetic testing for consumers, data mining, transcriptomic analysis, and the role of science and health professionals in the commercialization of nutrigenomics and nutrigenetics. The book also examines industry–academia partnerships as a nexus between the science and its commercialization by the food industry. These partnerships will be an important determinant of what value the technologies bring, not only to the market but to the wider health and well-being of society. Exploring how nutrigenomics and nutrigenetics can help modulate disease risk, this timely book brings together stimulating, well-thought-out perspectives from established and emerging researchers. It provides valuable information on a subject that is becoming increasingly important for nutritionists, dieticians, and clinical professionals, as well as for the food industry and research community.

Biochemistry of Oxidative Stress

Author: Ricardo J. Gelpi
Publisher: Springer
ISBN: 3319458655
Format: PDF, Kindle
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The strongest point of this book titled “Biochemistry of Oxidative Stress: Physiopathology and Clinical Aspects”, is that the academic and scientific background of the authors/editors guarantee the authorship of a book comprising all aspects of oxidative stress, ranging from very molecular aspects, to clinical application, including the antioxidant therapy. Of particular importance is the fact that the aforementioned aspects are described in the book in a general section and in three different and important pathologies, such as cardiovascular diseases, neurodegenerative diseases, and cancer. The importance of these pathologies lays in the fact that, taken separately or together, they represent by far the leading cause of death in the world. Finally, all the chapters have been written by highly recognized authorities in the field of their investigations. At least to our knowledge, this is the first book with this characteristics in the field of oxidative stress.

Pain Free Biochemistry

Author: Paul C. Engel
Publisher: John Wiley & Sons
ISBN: 0470722967
Format: PDF, Mobi
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"It’s not every day that one picks up a textbook that can claim to occupy a unique niche, given the multitude of scientific textbooks that are vying for a medical readership. However, with the recent publication of 'Pain-Free Biochemistry: An Essential Guide for the Health Sciences', which is specifically aimed at students of medicine and nursing, one could be left wondering just why nobody thought of this sooner.” –Irish Medical Times, September 14, 2010 If you are an undergraduate nursing or healthcare student about to embark on a short course in biochemistry and feel daunted by the prospect because you’ve done very little chemistry in the past, found it difficult or studied it so long ago you’ve forgotten it all, then this is the book for you. Equally, if clinical practice has brought you back to biochemistry just when you were hoping you could forget it all, this could be your lifeline! Having taught biochemistry to all sorts of students, from nurses to chemical engineers, for more than 30 years, Professor Paul Engel knows how to take the ‘pain’ out of your studies. For those who are a bit wobbly on molecules, bonds, ions, etc. this text also has just enough supporting chemistry slipped in where appropriate to help things make sense. Accessible, enjoyable to read and packed with a wealth of clinical examples from heart disease to cancer and blood clotting to antibiotics, this handy textbook will reveal how biochemistry is fundamental to clinical practice and everyday life. Drugs, diet, disease, DNA – it all comes down to biochemistry. Key Features: Easy to digest: ‘Bite sized’ topics lead you through essential biochemistry without going into intimidating detail. Doesn’t assume you’ve studied chemistry before: Focuses on key concepts and provides all the basic chemistry you might need. Colour coded: Specially designed so you can see, at a glance, which chapters focus on underpinning chemistry, which on basic biochemistry and which on clinical applications. Clinically relevant:Topical examples throughout the text show how getting to grips with biochemistry will help you succeed in healthcare practice. Reinforces your learning: Includes numerous self-test questions with answers throughout. Companion website includes: A complete set of figures from within the book. Extended MCQs with answers and further explanation where relevant.