Fundamentals of Enzyme Kinetics

Author: Athel Cornish-Bowden
Publisher: Elsevier
ISBN: 1483161196
Format: PDF, ePub
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Fundamentals of Enzyme Kinetics details the rate of reactions catalyzed by different enzymes and the effects of varying the conditions on them. The book includes the basic principles of chemical kinetics, especially the order of a reaction and its rate constraints. The text also gives an introduction to enzyme kinetics - the idea of an enzyme-substrate complex; the Michaelis-Menten equation; the steady state treatment; and the validity of its assumption. Practical considerations, the derivation of steady-state rate equations, inhibitors and activators, and two-substrate reactions are also explained. Problems after the end of each chapter have also been added, as well as their solutions at the end of the book, to test the readers' learning. The text is highly recommended for undergraduate students in biochemistry who wish to study about enzymes or focus completely on enzymology, as most of the mathematics used in this book, which have been explained in detail to remove most barriers of understanding, is elementary.

Enzymkinetik

Author: Hans Bisswanger
Publisher: Wiley-Blackwell
ISBN: 9783527300969
Format: PDF, Mobi
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Mit diesem Buch verfügen Biochemiker, Biologen und Mediziner - Studierende und Wissenschaftler - über eines der ausführlichsten Werke auf dem Gebiet der Enzymkinetik in aktualisierter und erweiterter Form. Der Text ist eine benutzerfreundliche, ausgewogene Mischung aus Theorie und Praxis. Alle wichtigen theoretischen Aspekte werden auch dem Einsteiger verständlich vermittelt. Dabei wird Wert darauf gelegt, daß stets der Bezug zum biologischen System sichtbar bleibt. Ein ausführlicher methodischer Teil gibt dem Praktiker im Labor eine wertvolle Unterstützung für die optimale Planung und Durchführung seiner Versuche. Methoden zur Bestimmung multipler Gleichgewichte, Kalorimetrie, die Messung schneller Reaktionen sowie elektrochemische und spektroskopische Methoden werden eingehend beschrieben. Das besondere Plus: die CD-ROM mit der weiterentwickelten und benutzerfreundlichen Version des zugehörigen Enzymkinetikprogramms.

Enzyme Kinetics for Systems Biology

Author: Herbert M. Sauro
Publisher: Future Skill Software
ISBN: 0982477317
Format: PDF, Mobi
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The 2nd edition has recently been published, the 1st edition has therefore been reduced in price by 20%. Enzyme Kinetics for System Biology is geared towards those who need a reference or classroom textbook that describes the various rate laws one can use to build computer models of cellular networks. The book covers commonly addressed topics such as rapid-equilibrium and steady state kinetics, including chapters on inhibitors, activators, cooperatively and allostery. The text book also includes topics more relevant to systems biology; these include chapters on elasticities, generalized rate laws and kinetics laws used to describe gene expression. Exercises are provided in most chapters with a summary of all the major kinetic rate laws in an appendix. Chapters include: Reaction Kinetics Elasticities Basic Enzyme Kinetics Enzyme Inhibition and Activation Multireactant Rate Laws Cooperativity Allostery Generalized Rate Laws Kinetics of Gene Regulation Basic Thermodynamics Current Print version: 1.08 Original publication date: April 2011

Enzyme Kinetics in Drug Metabolism

Author: Swati Nagar
Publisher: Humana Press
ISBN: 9781493960460
Format: PDF
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Drug metabolism and transport are very important facets within the discipline of pharmaceutical sciences, with enzyme kinetic concepts utilized regularly in characterizing and modeling the disposition and elimination of drugs. Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications focuses on very practical aspects of applying kinetic principles to drug metabolizing enzymes and transporters. Divided into five convenient sections, topics include the fundamental principles of enzyme kinetics, the kinetics of oxidative and conjugative drug metabolizing enzymes and drug transporters, modeling approaches for both drug metabolizing enzymes and transporters including novel systems biology approaches, understanding of variability both experimental and interindividual (pharmacogenomic), and case studies that provide real life examples of applying these principles. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics especially suitable for the novice, in some cases step-by-step, readily reproducible protocols, and insights to help with troubleshooting and avoiding known pitfalls with extensive cross referencing to assist in learning. Authoritative and easily accessible, Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications serves as a very practical teaching tool for novice, non-mathematically trained scientists interested in these fundamental concepts and as an aid for their supervisors in teaching these principles.

Enzyme Technology

Author: Martin F. Chaplin
Publisher: CUP Archive
ISBN: 9780521348843
Format: PDF, Docs
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This textbook provides a clear and authoritative guide to the principles and practice of the utilization of enzymes in biotechnology. Enzymes have increasingly important applications in the food and pharmaceutical industry, in medicine, and as biosensors.

Fundamentals of Receptor Enzyme and Transport Kinetics 1993

Author: John C. Matthews
Publisher: CRC Press
ISBN: 135136457X
Format: PDF, ePub
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Fundamentals of Receptor, Enzyme, and Transport Kinetics is the first book to pull together the most important topics in receptor, enzyme, and transport kinetics into a concise, easy-to-use format. Numerous equations are included, and key equations are graphed. For each graphed equation, important features are carefully explained. The book is organized so that simple material is presented first, providing a firm foundation on which to cover the advanced topics which appear later. Terminology used throughout the book is consistent with that used in scientific literature, and concepts are explained using analogies from daily life. The book also features two important appendices that will be particularly useful learning tools. The first appendix outlines all of the key equations from the text and indicates their use. The second appendix is a set of sample calculation problems and their solutions. Fundamentals of Receptor, Enzyme, and Transport Kinetics is an excellent text/reference for pharmacologists, biological chemists, experimental biologists, neurochemists, neurotoxicologists, physiologists, and toxicologists. It is also suitable as a graduate-level text in pharmacology and medical pharmacology.

Enzyme Kinetics Catalysis and Control

Author: Daniel L. Purich
Publisher: Elsevier
ISBN: 0123809258
Format: PDF, ePub, Docs
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Far more than a comprehensive treatise on initial-rate and fast-reaction kinetics, this one-of-a-kind desk reference places enzyme science in the fuller context of the organic, inorganic, and physical chemical processes occurring within enzyme active sites. Drawing on 2600 references, Enzyme Kinetics: Catalysis & Control develops all the kinetic tools needed to define enzyme catalysis, spanning the entire spectrum (from the basics of chemical kinetics and practical advice on rate measurement, to the very latest work on single-molecule kinetics and mechanoenzyme force generation), while also focusing on the persuasive power of kinetic isotope effects, the design of high-potency drugs, and the behavior of regulatory enzymes. Historical analysis of kinetic principles including advanced enzyme science Provides both theoretical and practical measurements tools Coverage of single molecular kinetics Examination of force generation mechanisms Discussion of organic and inorganic enzyme reactions

Enzyme Kinetics

Author: Hans Bisswanger
Publisher: John Wiley & Sons
ISBN: 3527622039
Format: PDF, Docs
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This new, expanded and updated edition of the user-friendly and comprehensive treatise on enzyme kinetics expertly balances theory and practice. This is an indispensable aid for advanced students and professionals working with enzymes, whether biochemists, biotechnologists, chemical biologists, pharmacologists or bioengineers in academia, industry and clinical research.

Enzyme Kinetics

Author: Arthur R. Schulz
Publisher: Cambridge University Press
ISBN: 9780521449502
Format: PDF, Mobi
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Problems are included at the end of each chapter and their solutions are found at the end of the book.