Gas Chromatography and Mass Spectrometry A Practical Guide

Author: O. David Sparkman
Publisher: Academic Press
ISBN: 9780080920153
Format: PDF, ePub, Mobi
Download Now
The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated. Covers the practical instruction necessary for successful operation of GC/MS equipment Reviews the latest advances in instrumentation, ionization methods, and quantitation Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner A true benchtop reference A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS) Quick References to data interpretation Ready source for information on new analyses

Handbuch der GC MS

Author: Hans-Joachim Hübschmann
Publisher: Wiley-VCH
ISBN: 9783527286041
Format: PDF, ePub
Download Now
Endlich gibt es ein umfassendes Handbuch für den praktischen Einsatz der GC/MS. Das Themenspektrum reicht von der angepaßten Probenvorbereitung, über die Auftrennung von Gemischen, die universellen und selektiven Möglichkeiten der massenspektrometrischen Detektion bis hin zur qualitativen und quantitativen Auswertung. Die ausführlich beschriebenen Applikationen zeigen die unterschiedlichen Einsatzbereiche von GC/MS-Systemen auf. Zahlreiche Tabellen unterstützen den Anwender bei der Erstellung neuer Analysenmethoden und bei der Auswertung der Ergebnisse. Die Beschreibung möglicher Fehlerquellen hilft dem Leser, falsche Messungen zu vermeiden. Dieses aktuelle Handbuch, das die neuesten Gerätetechniken berücksichtigt, wendet sich an alle Benutzer von GC/MS-Geräten sowie an die verantwortlichen Leiter von Laboratorien.

Practical Gas Chromatography

Author: Katja Dettmer-Wilde
Publisher: Springer
ISBN: 3642546404
Format: PDF, ePub, Mobi
Download Now
Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.

Current Practice of Gas Chromatography Mass Spectrometry

Author: Wilfried M.A. Niessen
Publisher: CRC Press
ISBN: 9781420029512
Format: PDF, ePub, Mobi
Download Now
This volume details the principles and instrumentation of gas chromatography-mass spectrometry (CG-MS), and outlines industrial, environmental, pharmaceutical, clinical, toxicological, forensic and food-related applications, revealing findings from the laboratories of 40 contributing scientists around the world using GC-MS in practice. It describes upstream and downstream applications of GC-MS in the petroleum industry and identifies chlorinated compounds in the environment with quadrupole ion-trap technology and high-resolution sector instruments.

Liquid Chromatography Mass Spectrometry

Author: R. E. Ardrey
Publisher: John Wiley & Sons
ISBN: 9780471498018
Format: PDF, ePub
Download Now
This series of books provides coverage of all of the majoranalytical techniques and their application in the most importantareas of physical, life and materials science. Each text ispresented in an open learning/distance learning style, in which thelearning objectives are clearly identified. The reader'sunderstanding of the material is constantly evaluated by the use ofself-assessment and discussion questions. The combination of gas chromatography with mass spectrometry(GC-MS) has been a routine analytical tool for many years, whilethe related hybrid technique of liquid chromatography-massspectrometry (LC-MS) is a rather more recent development. However,with the advent of new interfacing technology, the benefits of thispowerful hybrid analytical method are now currently being realised,as witnessed by the exponential growth in applications of thistechnique in both the chemical and life sciences. The topics covered in this text include the following: * The basic principles of liquid chromatography and massspectrometry * The limitations of the component techniques when used inisolation, and how a combination of the two allows these to beovercome * Descriptions of the various approaches, including thermospray,electrospray and atmospheric pressure chemical ionization, whichare used to interface the two techniques, along with the advantagesand disadvantages of each system * Illustrative examples of the applications of LC-MS, including themolecular weight and structure determinations of both biopolymersand low-molecular-compounds, along with the development ofquantitative methods Key features include: * The provision of many discussion and self-assessment questionsthroughout the text, thus providing opportunities for testing thereader's understanding of the subject matter * Presented in the AnTS (open learning/distance learning) style, itis ideal for use as both a self-study guide and as the basis of ataught course * A comprehensive bibliography, including books, papers/articles injournals and on websites, along with specific references for theindividual chapters, to guide the reader to more specialised textsand original sources Written with a student audience in mind, this text will provide aninvaluable introduction to this increasingly important analyticaltandem technique.

Advanced Techniques in Gas Chromatography Mass Spectrometry GC MS MS and GC TOF MS for Environmental Chemistry

Author:
Publisher: Newnes
ISBN: 0444626247
Format: PDF, ePub, Docs
Download Now
Gas chromatography mass spectrometry (GC-MS) has been the technique of choice of analytical scientists for many years. The latest developments in instrumentation, including tandem mass spectrometry (MS-MS) and time-of-flight (TOF) detectors, have opened up and broadened the scope of environmental analytical chemistry. This book summarizes the major advances and relevant applications of GC-MS techniques over the last 10 years, with chapters by leading authors in the field of environmental chemistry. The authors are drawn from academia, industry and government. The book is organized in three main parts. Part I covers applications of basic GC-MS to solve environmental-related problems. Part II focuses on GC-MS-MS instrumentation for the analyses of a broad range of analysis in environmental samples (pesticides, persistent organic pollutants, endocrine disruptors, etc.). Part III covers the use of more advanced GC-MS techniques using low- and high-resolution mass spectrometry for many applications related to the environment, food and industry. Summarizes the major advances of GC-MS techniques in the last decade Presents relevant applications of GC-MS techniques Covers academic, industrial and governmental sectors

GC MS

Author: Marvin C. McMaster
Publisher: Wiley-VCH
ISBN: 9780471248262
Format: PDF, Mobi
Download Now
A unique practical guide to building, using, and maintaining a complete GC/MS system. Though gas chromatography/mass spectrometry (GC/MS) is one of the most effective and popular methods of separating, identifying, and quantifying compounds in complex mixtures, there have been no comprehensive handbooks to date that clearly explain the setup and maintenance of a functional GC/MS system. Now Marvin and Christopher McMaster have created the hands-on resource that researchers and students need to get their own systems up and running quickly. Covering everything from necessary components to tuning, troubleshooting, and processing data, it allows even those with little prior knowledge of GC/MS to perform their own analyses and gather the data they require. GC/MS: A Practical User's Guide contains: * Full coverage of vital equipment, including the function, costs, and advantages of both desktop and floor-standing systems * A walkthrough of a basic GC/MS analysis and an examination of key methods of structural data interpretation * Extensive information on GC/MS system optimization * An exploration of the various research and environmental uses of GC/MS systems * An extended section on liquid chromatography/mass spectrometry to enhance comprehension of the gas method. For organic, analytical, clinical, environmental, and forensic chemists in all types of laboratories-and for students in all of these specialties -this book will be an invaluable companion for years to come.

Handbook of Food Analysis Third Edition Two Volume Set

Author: Leo M.L. Nollet
Publisher: CRC Press
ISBN: 1482297841
Format: PDF, Kindle
Download Now
Updated to reflect changes in the industry during the last ten years, The Handbook of Food Analysis, Third Edition covers the new analysis systems, optimization of existing techniques, and automation and miniaturization methods. Under the editorial guidance of food science pioneer Leo M.L. Nollet and new editor Fidel Toldra, the chapters take an in-depth look at how to determine the chemical composition of foodstuffs at the level required to safeguard consumer health, well-being, and safety. See What’s New in the Third Edition: Discussions of analysis techniques of rheological, thermal, and flavor properties of food Examination of methods and techniques in food analysis Coverage amines, flavorings, and food traceability Unparalleled in breadth and depth, the set delineates the physical and chemical properties of nutrients and other food components. It presents an exhaustive compilation of analytical methods and provides step-by-step descriptions of preparation, detection, separation, derivatization, and clean-up techniques. It also assesses the relative advantage, accuracy, and reliability of each procedure. Volume 1 covers Physical and Sensory Properties; Additives, Adulteration, and Traceability; and Nutritional Analysis while Volume 2 covers Residues and Other Food Components; as well as Methods, Techniques, and Instruments. Together the two volumes examine both parts of food analysis: analytical and quantitative testing of product composition and guaranteeing product quality and safety as productivity increases. These volumes give you the analytical foundation required to develop food products free from contaminants and toxins and the tools to control their safety.