Gene and Cell Therapy

Author: Nancy Smyth Templeton
Publisher: CRC Press
ISBN: 9780849387999
Format: PDF, Mobi
Download Now
Since the publication of the second edition of this book in 2004, gene therapy and cell therapy clinical trials have yielded some remarkable successes and some disappointing failures. Now in its third edition, Gene and Cell Therapy: Therapeutic Mechanisms and Strategies assembles many of the new technical advances in gene delivery, clinical applications, and new approaches to the regulation and modification of gene expression. New Topics Covered in this Edition: Gene and Cell Therapies for Diabetes and Cardiovascular Diseases Clinical Trials Human Embryonic Stem Cells Tissue Engineering Combined with Cell Therapies Novel Polymers Relevant Nanotechnologies SiRNA Therapeutic Strategies Dendrimer Technologies Comprised of contributions from international experts, this book begins with a discussion of delivery systems and therapeutic strategies, exploring retroviral vectors and adenovirus vectors, as well as other therapeutic strategies. The middle section focuses on gene expression and detection, followed by an examination of various therapeutic strategies for individual diseases, including hematopoietic disorders, cardiovascular conditions, cancer, diabetes, cystic fibrosis, neurological disorders, and childhood-onset blindness. The final section discusses recent clinical trials and regulatory issues surrounding the new technology. This compendium is assembled by noted molecular biologist and biochemist Nancy Smyth Templeton. Baylor College of Medicine and several other institutions have used Dr. Templeton’s non-viral therapeutics in clinical trials for the treatment of lung, breast, head and neck, and pancreatic cancers, as well as Hepatitis B and C. She continues to work at the forefront of research in gene and cell therapies. Her contributions, as well as those contained in this volume, are sure to advance the state of the art of these revolutionary life-saving technologies.

Multifunctional Nanocarriers for Contemporary Healthcare Applications

Author: Barkat, Md. Abul
Publisher: IGI Global
ISBN: 1522547827
Format: PDF
Download Now
Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.

Professional Voice Fourth Edition

Author: Robert Thayer Sataloff
Publisher: Plural Publishing
ISBN: 1597567108
Format: PDF, Mobi
Download Now
The most comprehensive reference on voice care and science ever published! Substantially revised and updated since the previous edition published in 2005, Professional Voice: The Science and Art of Clinical Care, Fourth Edition provides the latest advances in the field of voice care and science. In three volumes, it covers basic science, clinical assessment, nonsurgical treatments, and surgical management. Twenty new chapters have been added. These include an in-depth chapter on pediatric voice disorders, chapters detailing how hormonal contraception, autoimmune disorders, and thyroid disorders affect the voice, as well as chapters on the evolution of technology in the voice care field, and advances in imaging of the voice production system. The appendices also have been updated. They include a summary of the phonetic alphabet in five languages, clinical history and examination forms, a special history form translated into 15 languages, sample reports from a clinical voice evaluation, voice therapy exercise lists, and others. The multidisciplinary glossary remains an invaluable resource. Key Features With contributions from a Who's Who of voice across multiple disciplines120 chapters covering all aspects of voice science and clinical careFeatures case examples plus practical appendices including multi-lingual forms and sample reports and exercise listsComprehensive indexMultidisciplinary glossary What's New Available in print or electronic format20 new chaptersExtensively revised and reorganized chaptersMany more color photographs, illustrations, and case examplesFully updated comprehensive glossaryMajor revisions with extensive new information and illustrations, especially on voice surgery, reflux, and structural abnormalities New Chapters 1. Formation of the Larynx: From Hox Genes to Critical Periods 2. High-Speed Digital Imaging 3. Evolution of Technology 4. Magnetic Resonance Imaging of the Voice Production System 5. Pediatric Voice Disorders 6. The Vocal Effects of Thyroid Disorders and Their Treatment 7. The Effects of Hormonal Contraception on the Voice 8. Cough and the Unified Airway 9. Autoimmune Disorders 10. Respiratory Behaviors and Vocal Tract Issues in Wind Instrumentalists 11. Amateur and Professional Child Singers: Pedagogy and Related Issues 12. Safety of Laryngology Procedures Commonly Performed in the Office 13. The Professional Voice Practice 14. Medical-Legal Implications of Professional Voice Care 15. The Physician as Expert Witness 16. Laryngeal Neurophysiology 17. The Academic Practice of Medicine 18. Teamwork 19. Medical Evaluation Prior to Voice Lessons 20. Why Study Music? Intended Audiences Individuals While written primarily for physicians and surgeons, this comprehensive work is also designed to be used by (and written in language accessible to) speech-language pathologists, singing voice specialists, acting voice specialists, voice teachers, voice/singing performers, nurses, nurse practitioners, physician assistants, and others involved in the care and maintenance of the human voice. Libraries It is a must-have reference for medical and academic libraries at institutions with otolaryngology, speech-language pathology, music, nursing and other programs related to the human voice.

Solid Cancer New Insights for the Healthcare Professional 2012 Edition

Author:
Publisher: ScholarlyEditions
ISBN: 1464972702
Format: PDF, Kindle
Download Now
Solid Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Solid Cancer in a concise format. The editors have built Solid Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Solid Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Solid Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Molekulare Humangenetik

Author: Tom Strachan
Publisher: Spektrum Akademischer Verlag
ISBN: 9783827414939
Format: PDF, ePub
Download Now
Die vorliegende 3. Auflage der Molekularen Humangenetik ist völlig neu überarbeitet - unter Berücksichtigung der Entdeckungen, die im Zuge und in der Folge des Human Genome Project gemacht wurden. Die einführenden Kapitel (Teil I) beschreiben die Grundlagen wie DNA-Struktur und -Funktion, Chromosomen, Zellen und Entwicklung, Stammbaumanalysen und grundlegende Techniken im Labor. In Teil II werden die verschiedenen Genomsequenzierungsprojekte und die dadurch ermöglichten Einblicke in Organisation, Expression, Variabilität und Evolution des menschlichen Genoms gezeigt. Die Kartierung, Identifizierung und Diagnose der Ursachen von mendelnden und komplexen Krankheiten sowie Krebs ist Schwerpunkt von Teil III. Der letzte Teil gibt Ausblicke auf die funktionelle Genomik und Bioinformatik, auf Tiermodelle und Therapien. Das Buch soll eine Brücke bilden zwischen den grundlegenden Lehrbüchern und der Forschungsliteratur, sodass auch Interessierte mit relativ wenig Hintergrundwissen zum Thema die neuesten Forschungsergebnisse lesen und beurteilen können.

Uveitis E Book

Author: Robert B. Nussenblatt
Publisher: Elsevier Health Sciences
ISBN: 032308401X
Format: PDF, ePub
Download Now
Uveitis is the comprehensive reference you need for a balanced approach to basic science and clinical application. Robert B. Nussenblatt and Scott M. Whitcup provide a cohesive and integrated discussion of the topic, covering everything from the role of surgery to AIDS to anterior uveitis and more. This new edition even includes full color throughout with 400 photographs and illustrations. Comprehensive yet readable, this resource packs everything you need in patient evaluation and management to achieve optimal results. Covers the medical, pharmacological, and surgical treatment of uveitis to serve as a complete overview of all uveitis related information. Features multiple chapters on diagnostic approach to help you overcome challenges in making accurate diagnoses. Provides additional information on inflammatory eye diseases in chapters on scleritis, masquerade syndromes, and the role of inflammation in other ocular diseases for more comprehensive coverage. Includes illustrated case studies to supplement major clinical points and provide insight into real situations that you can apply in practice. Highlights important information in key points boxes that make it easy to locate crucial points on each topic. Features significant updates to the chapters on the role of surgery in the patient with uveitis, acquired immune deficiency syndrome, anterior uveitis, white dot syndromes, and masquerade syndromes. Covers advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Presents photographs in full color to better prepare you for actual clinical diagnosis.

Fishman s Pulmonary Diseases and Disorders Fourth Edition

Author: Alfred P. Fishman
Publisher: McGraw Hill Professional
ISBN: 0071641092
Format: PDF, Docs
Download Now
A complete guide to the entire field of respiratory medicine-with all-new content and a streamlined new design First published in 1980, Fishman's Pulmonary Diseases & Disorders is the classic reference through which pulmonary physicians have gained a commanding look at the diagnosis and treatment of pulmonary diseases and disorders. Edited by the world's foremost authorities, Fishman's Pulmonary Diseases & Disorders covers exactly what you need to know about lung diseases and their management, including sleep-disordered breathing, COPD, emphysema, and lung cancer, as well as new technological advances and imaging techniques. This unparalleled two-volume resource begins with a compelling overview of up-to-date clinical perspectives, along with the scientific basis of lung function health and disease. It then provides turnkey information on everything from respiratory disease signs and symptoms, to obstructive lung diseases, occupational and environmental disorders, and specific respiratory conditions such as infections diseases of the lungs and acute respiratory failure. New to the 4th Edition: Information on recent advancements in many clinically relevant areas of pulmonary medicine Update to the infectious diseases chapters that reflect current practice guidelines and recent antimicrobial developments Clearer connection between fundamental science concepts and clinical applications, which reflect current scientific research Latest information on sleep disorders Review of recent recommendations of the American Thoracic Society and European Respiratory Society for the accurate interpretation of pulmonary function tests Appendices that include a respiratory questionnaire, normal values, and commonly used terms & symbols