Genetic Twists of Fate

Author: Stanley Fields
Publisher: MIT Press
ISBN: 0262289008
Format: PDF, ePub, Mobi
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News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

Twisting Fate

Author: Pamela Munster
Publisher: The Experiment
ISBN: 1615195149
Format: PDF, ePub, Mobi
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A practical yet personal guide to the medical and emotional facets of breast cancer, from a woman who’s made her living researching the disease—and lived through it herself A leading oncologist at the University of California San Francisco, Dr. Pamela Munster has advised thousands of women on how to deal with the life-altering diagnosis of breast cancer. But when she got a call saying that her own mammogram showed “irregularities,” she found herself experiencing a whole new side of the disease she thought she was an expert in. Weaving together her personal story with her team’s groundbreaking research on the BRCA gene—responsible for not only breast cancer but also for many other inherited cancers affecting both women and men—Twisting Fate is an inspiring guide to living with BRCA mutations. With authority, insight, and compassion, Dr. Munster uses her voice to create a safe space for genuine healing and honesty in a world otherwise dominated by fear.

The Story Within

Author: Amy Boesky
Publisher: JHU Press
ISBN: 1421410974
Format: PDF, Docs
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The contributors to The Story Within share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available. More broadly, they consider how genetic information shapes the ways we see ourselves, the world, and our actions within it. People affected by genetic disease respond to such choices in varied and personal ways. These writers reflect that breadth of response, yet they share the desire to challenge a restricted sense of what "health" is or whose life has value. They write hoping to expand conversations about genetics and identity—to deepen debate and generate questions. They or their families are affected by Huntington’s disease, Alzheimer’s disease, cancer, genetic deafness or blindness, schizophrenia, cystic fibrosis, Tay-Sachs, hypertrophic cardiomyopathy, fragile X, or Fanconi anemia. All of their stories remind us that genetic health is complicated, dynamic, and above all, deeply personal. Contributors Misha Angrist, Amy Boesky, Kelly Cupo, Michael Downing, Clare Dunsford, Mara Faulkner, Christine Kehl O’Hagan, Charlie Pierce, Kate Preskenis, Emily Rapp, Jennifer Rosner, Joanna Rudnick, Anabel Stenzel (deceased), Isabel Stenzel Byrnes, Laurie Strongin, Patrick Tracey, Alice Wexler -- Alexandra Stern, University of Michigan, author of Telling Genes: The Story of Genetic Counseling in AmericaRita Charon, M.D., Ph.D., Program in Narrative Medicine at Columbia University, author of Narrative Medicine: Honoring the Stories of IllnessPatrick Tracey

Genes Chromosomes and Disease

Author: Nicholas Wright Gillham
Publisher: FT Press
ISBN: 9780132623247
Format: PDF
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This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

Mercies in Disguise

Author: Gina Kolata
Publisher: St. Martin's Press
ISBN: 1250123992
Format: PDF, ePub, Mobi
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"[Kolata] is a gifted storyteller. Her account of the Baxleys... is both engrossing and distressing... Kolata's book raises crucial questions about knowledge that can be both vital and fatal, both pallative and dangerous." —Andrew Solomon, The New York Review of Books New York Times science reporter Gina Kolata follows a family through genetic illness and one courageous daughter who decides her fate shall no longer be decided by a genetic flaw. The phone rings. The doctor from California is on the line. “Are you ready Amanda?” The two people Amanda Baxley loves the most had begged her not to be tested—at least, not now. But she had to find out. If your family carried a mutated gene that foretold a brutal illness and you were offered the chance to find out if you’d inherited it, would you do it? Would you walk toward the problem, bravely accepting whatever answer came your way? Or would you avoid the potential bad news as long as possible? In Mercies in Disguise, acclaimed New York Times science reporter and bestselling author Gina Kolata tells the story of the Baxleys, an almost archetypal family in a small town in South Carolina. A proud and determined clan, many of them doctors, they are struck one by one with an inscrutable illness. They finally discover the cause of the disease after a remarkable sequence of events that many saw as providential. Meanwhile, science, progressing for a half a century along a parallel track, had handed the Baxleys a resolution—not a cure, but a blood test that would reveal who had the gene for the disease and who did not. And science would offer another dilemma—fertility specialists had created a way to spare the children through an expensive process. A work of narrative nonfiction, Mercies in Disguise is the story of a family that took matters into its own hands when the medical world abandoned them. It’s a story of a family that had to deal with unspeakable tragedy and yet did not allow it to tear them apart. And it is the story of a young woman—Amanda Baxley—who faced the future head on, determined to find a way to disrupt her family’s destiny.

Gene Defense

Author: Joy Ashe
Publisher: Xlibris Corporation
ISBN: 1456804561
Format: PDF
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This fast-paced genetic thriller with a strong political undertow begins with a phone call plea for help to Boston-based attorney Paeton Weaver by her sister, Casey Bell, after the discovery of her philanthropist husbands bloodied body, supposedly, by his own hand. Local Florida authorities are suspicious about the circumstances of Leonard L. Bells death. His death comes in the year 2013, post the U.S. presidential inauguration. Paeton Weaver takes the reader on a disturbing journey to examine the social, psychological and legal ramifi cations of genetic social engineering when under new US leadership, citizens become valued based on genetic characteristics. Paeton discovers a dark Weaver family history through a series of nightmares. Secrets kept hidden over two hundred years reveal ghastly murders. She ponders her own genetic fate. In 2013, the American way of life, from our health care provisions, justice system, medical outcomes, jobs, friends, family, water, food supply and our very own fate, depends upon our DNA. No one can hide from their genetic history. What defense do we have against our genes?

The Applied Genetics of Humans Animals Plants and Fungi 2nd Edition

Author: Bernard C Lamb
Publisher: World Scientific Publishing Company
ISBN: 1911299182
Format: PDF, ePub, Mobi
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A concise, clear writing style and a detailed and rich coverage of topics are the reasons that students found the first edition of the book so engaging and useful. Riding on this wave, all chapters within the second edition of this popular book have been thoroughly updated and expanded, especially the human and animal materials. A wider range of animals is covered, including dogs and cats as well as farm animals. The use of cord blood for therapy, pre-implantation genetic diagnosis and animal cloning are also explored and dealt with.

Time Love Memory

Author: Jonathan Weiner
Publisher: Vintage
ISBN: 0804153361
Format: PDF, ePub
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How much of our fate is decided before we are born? Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives. Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.

Super Genes

Author: Deepak Chopra, M.D.
Publisher: Harmony
ISBN: 0804140146
Format: PDF, Mobi
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The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled. "You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting." Learning how to shape your gene activity is at the heart of this exciting and eagerly-anticipated book from the bestselling duo behind Super Brain, which became a nationwide hit on public television. For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago. The impact on prevention, immunity, diet, aging, and chronic disorders is unparalleled.

The Wandering Gene and the Indian Princess Race Religion and DNA

Author: Jeff Wheelwright
Publisher: W. W. Norton & Company
ISBN: 039308342X
Format: PDF, ePub, Docs
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A brilliant and emotionally resonant exploration of science and family history. A vibrant young Hispano woman, Shonnie Medina, inherits a breast-cancer mutation known as BRCA1.185delAG. It is a genetic variant characteristic of Jews. The Medinas knew they were descended from Native Americans and Spanish Catholics, but they did not know that they had Jewish ancestry as well. The mutation most likely sprang from Sephardic Jews hounded by the Spanish Inquisition. The discovery of the gene leads to a fascinating investigation of cultural history and modern genetics by Dr. Harry Ostrer and other experts on the DNA of Jewish populations. Set in the isolated San Luis Valley of Colorado, this beautiful and harrowing book tells of the Medina family’s five-hundred-year passage from medieval Spain to the American Southwest and of their surprising conversion from Catholicism to the Jehovah’s Witnesses in the 1980s. Rejecting conventional therapies in her struggle against cancer, Shonnie Medina died in 1999. Her life embodies a story that could change the way we think about race and faith.