Genetic Twists of Fate

Author: Stanley Fields
Publisher: MIT Press
ISBN: 0262289008
Format: PDF, ePub
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News stories report almost daily on the remarkable progress scientists are making in unraveling the genetic basis of disease and behavior. Meanwhile, new technologies are rapidly reducing the cost of reading someone's personal DNA (all six billion letters of it). Within the next ten years, hospitals may present parents with their newborn's complete DNA code along with her footprints and APGAR score. In Genetic Twists of Fate, distinguished geneticists Stanley Fields and Mark Johnston help us make sense of the genetic revolution that is upon us. Fields and Johnston tell real life stories that hinge on the inheritance of one tiny change rather than another in an individual's DNA: a mother wrongly accused of poisoning her young son when the true killer was a genetic disorder; the screen siren who could no longer remember her lines because of Alzheimer's disease; and the president who was treated with rat poison to prevent another heart attack. In an engaging and accessible style, Fields and Johnston explain what our personal DNA code is, how a few differences in its long list of DNA letters makes each of us unique, and how that code influences our appearance, our behavior, and our risk for such common diseases as diabetes or cancer.

The Story Within

Author: Amy Boesky
Publisher: JHU Press
ISBN: 1421410974
Format: PDF, ePub, Mobi
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The contributors to The Story Within share powerful experiences of living with genetic disorders. Their stories illustrate the complexities involved in making decisions about genetic diseases: whether to be tested, who to tell, whether to have children, and whether and how to treat children medically, if treatment is available. More broadly, they consider how genetic information shapes the ways we see ourselves, the world, and our actions within it. People affected by genetic disease respond to such choices in varied and personal ways. These writers reflect that breadth of response, yet they share the desire to challenge a restricted sense of what "health" is or whose life has value. They write hoping to expand conversations about genetics and identity—to deepen debate and generate questions. They or their families are affected by Huntington’s disease, Alzheimer’s disease, cancer, genetic deafness or blindness, schizophrenia, cystic fibrosis, Tay-Sachs, hypertrophic cardiomyopathy, fragile X, or Fanconi anemia. All of their stories remind us that genetic health is complicated, dynamic, and above all, deeply personal. Contributors Misha Angrist, Amy Boesky, Kelly Cupo, Michael Downing, Clare Dunsford, Mara Faulkner, Christine Kehl O’Hagan, Charlie Pierce, Kate Preskenis, Emily Rapp, Jennifer Rosner, Joanna Rudnick, Anabel Stenzel (deceased), Isabel Stenzel Byrnes, Laurie Strongin, Patrick Tracey, Alice Wexler -- Alexandra Stern, University of Michigan, author of Telling Genes: The Story of Genetic Counseling in AmericaRita Charon, M.D., Ph.D., Program in Narrative Medicine at Columbia University, author of Narrative Medicine: Honoring the Stories of IllnessPatrick Tracey

Genes Chromosomes and Disease

Author: Nicholas Wright Gillham
Publisher: FT Press
ISBN: 9780132623247
Format: PDF
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This very readable overview of the rise and transformations of medical genetics and of the eugenic impulses that have been inspired by the emerging understanding of the genetic basis of many diseases and disabilities is based on a popular nonmajors course, "Social Implications of Genetics," that Gillham gave for many years at Duke University. The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

Mapping Fate

Author: Alice Wexler
Publisher: Univ of California Press
ISBN: 9780520207417
Format: PDF
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Wexler tells the story of a family at risk for Huntington's disease, a hereditary, incurable, fatal disorder from which her own mother died. This graceful and eloquent account goes beyond the specifics of the disease to explore the dynamics of family secrets, of living at risk, and the drama and limits of biomedical research. Photos.

Twist of Fate

Author: Brad Hastings
Publisher: University Press of America
ISBN: 9780761839347
Format: PDF, ePub, Mobi
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From Ancient Greece to contemporary times, themes of fate and destiny have served as a central worldview for many. These compelling ideas have guided those in battle, and provided influence and inspirations for politicians, philosophers, and artists. Despite a pervasive concern with fate, we find that an explicit discussion of this construct is absent from psychological theory. Twist of Fate reconciles contemporary psychological research with the ancient and frequently held position of fatalism that was common in that era. The Greek mythological history of the "Moirae" (the triad of goddesses known as the "Fates") offers a unique perspective on human beings by illustrating how fate and destiny influence a variety of behaviors such as drug addiction, spirituality, sexual activity, aggression, and other applied psychological topics. An analysis of the "Moirae" integrates diverse ideas from evolutionary psychology, neuroscience, psychoanalysis, and Nietzsche's philosophy into a fatalistic view of the human personality. The analysis raises the issues of possibilities for personal change, the role of clinical interventions, and what role freedom actually plays in the human experience. Twist of Fate also accounts for recent developments in personality theory and research by shedding new light on findings from evolutionary psychology, narrative theory, and trait psychology. The result is an integrative personality theory that takes the reader from Nietzsche to neuroscience.

The Norma Gene

Author: M.E. Roufa
Publisher: Bitingduck Press LLC
ISBN: 1938463420
Format: PDF, Docs
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As the world’s first completely illegal clone of America’s 16th President, Abe Finkelstein grew up with just one wish: to live his life just like anybody else. But when you’re a living ringer for one of the country’s best-loved historical figures, privacy is hard to come by—especially when your face is on money. Across town, Norma Greenberg, one of the world’s many Marilyn Monroe clones, is struggling with identity issues of a different sort. It’s not easy going through life as a copy of the beautiful Norma Jeane Baker! When Abe is taken away by government agents eager to discover the secrets of his illustrious ancestor, Norma could be Abe’s last hope of escape—or, thanks to her kleptomania, his worst chance of recapture. With only their wits, a cigarette lighter, a bottle of perfume, and the disembodied arm of Richard Nixon, can Abe and Norma make it back to safety and anonymity?

Mercies in Disguise

Author: Gina Kolata
Publisher: St. Martin's Press
ISBN: 1250123992
Format: PDF
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"[Kolata] is a gifted storyteller. Her account of the Baxleys... is both engrossing and distressing... Kolata's book raises crucial questions about knowledge that can be both vital and fatal, both pallative and dangerous." —Andrew Solomon, The New York Review of Books New York Times science reporter Gina Kolata follows a family through genetic illness and one courageous daughter who decides her fate shall no longer be decided by a genetic flaw. The phone rings. The doctor from California is on the line. “Are you ready Amanda?” The two people Amanda Baxley loves the most had begged her not to be tested—at least, not now. But she had to find out. If your family carried a mutated gene that foretold a brutal illness and you were offered the chance to find out if you’d inherited it, would you do it? Would you walk toward the problem, bravely accepting whatever answer came your way? Or would you avoid the potential bad news as long as possible? In Mercies in Disguise, acclaimed New York Times science reporter and bestselling author Gina Kolata tells the story of the Baxleys, an almost archetypal family in a small town in South Carolina. A proud and determined clan, many of them doctors, they are struck one by one with an inscrutable illness. They finally discover the cause of the disease after a remarkable sequence of events that many saw as providential. Meanwhile, science, progressing for a half a century along a parallel track, had handed the Baxleys a resolution—not a cure, but a blood test that would reveal who had the gene for the disease and who did not. And science would offer another dilemma—fertility specialists had created a way to spare the children through an expensive process. A work of narrative nonfiction, Mercies in Disguise is the story of a family that took matters into its own hands when the medical world abandoned them. It’s a story of a family that had to deal with unspeakable tragedy and yet did not allow it to tear them apart. And it is the story of a young woman—Amanda Baxley—who faced the future head on, determined to find a way to disrupt her family’s destiny.

Super Genes

Author: Deepak Chopra, M.D.
Publisher: Harmony
ISBN: 0804140146
Format: PDF, ePub, Mobi
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The authors of the New York Times bestseller Super Brain present a bold new understanding of our genes and how simple changes in lifestyle can boost genetic activity. The leap into "radical well-being" is a promise waiting to be fulfilled. "You are not simply the sum total of the genes you were born with," writes Deepak Chopra and Rudy Tanzi. "You are the user and controller of your genes, the author of your biological story. No prospect in self-care is more exciting." Learning how to shape your gene activity is at the heart of this exciting and eagerly-anticipated book from the bestselling duo behind Super Brain, which became a nationwide hit on public television. For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago. The impact on prevention, immunity, diet, aging, and chronic disorders is unparalleled.

Money Changes Everything

Author: Jenny Offill
Publisher: Broadway Books
ISBN: 9780385521796
Format: PDF, Docs
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The editors of The Friend Who Got Away are back with a new anthology that will do for money what they did for women’s friendships. Ours is a culture of confession, yet money remains a distinctly taboo subject for most Americans. In this riveting anthology, a host of celebrated writers explore the complicated role money has played in their lives, whether they’re hiding from creditors or hiding a trust fund. This collection will touch a nerve with anyone who’s ever been afraid to reveal their bank balance. In these wide-ranging personal essays, Daniel Handler, Walter Kirn, Jill McCorkle, Meera Nair, Henry Alford, Susan Choi, and other acclaimed authors write with startling candor about how money has strengthened or undermined their closest relationships. Isabel Rose talks about the trials and tribulations of dating as an heiress. Tony Serra explains what led him to take a forty-year vow of poverty. September 11 widow Marian Fontana illuminates the heartbreak and moral complexities of victim compensation. Jonathan Dee reveals the debt that nearly did him in. And in paired essays, Fred Leebron and his wife Katherine Rhett discuss the way fights over money have shaken their marriage to the core again and again. We talk openly about our romantic disasters and family dramas, our problems at work and our battles with addiction. But when it comes to what is or is not in our wallets, we remain determinedly mum. Until now, that is. Money Changes Everything is the first anthology of its kind—an unflinching and on-the-record collection of essays filled with entertaining and enlightening insights into why we spend, save, and steal. The pieces in Money Changes Everything range from the comic to the harrowing, yet they all reveal the complex, emotionally charged role money plays in our lives by shattering the wall of silence that has long surrounded this topic.

Ursula Under

Author: Ingrid Hill
Publisher: Algonquin Books
ISBN: 1565123883
Format: PDF
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Ursula Wong, a racially mixed child, falls down a mine shaft and rescue efforts go on against a background of stories about her remarkable ancestors.