Glowing Genes

Author: Marc Zimmer
Publisher: Pyr Books
ISBN:
Format: PDF, Mobi
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Marc Zimmer has written the first popular science book on an amazing new area of biotechnology that will help fight cancer, create new products, improve agriculture, and combat terrorism. For more than one hundred and sixty million years, green fluorescent protein has existed in one species of jellyfish. In 1994 it was cloned, giving rise to a host of useful and potentially revolutionary applications in biotechnology. Today researchers are using this ancient glowing protein to pursue exciting new discoveries, from tracking the process of bacterial infection to detecting chemical and biological agents planted by terrorists. A recognized expert in this field, Zimmer begins with an overview of the many uses of these glowing genes to kill and image cancer cells, monitor bacterial infections, and light up in the presence of pollution. He then discusses the biological reasons that glowing proteins first evolved in jellyfish and fireflies, and looks at the history of bioluminescence and the dedicated scientists who devoted their careers to explaining this phenomenon. The story of how "glowing genes" were located, cloned, and then mass-produced is in itself a fascinating tale. Zimmer next turns to the serious, and not-so-serious, uses of fluorescent proteins. In agriculture it may soon be possible to produce crops that signal dryness by glowing. In industry a red fluorescent protein originally found in corals may find a use in sheep as a substitute for environmentally harmful wool dyes. Furthermore, the glowing gene revolution has led to significantly more humane treatment of laboratory animals. No longer must animal lives be sacrificed to understand disease processes; now researchers can observe the spread of cancer and infections by treating animals with green fluorescent genes and similar proteins. In the fight against terrorism a glowing gene has been created that lights up in the presence of anthrax spores, chemical warfare agents, and landmines. And in a completely different arena, we have already seen the emergence of "transgenic art" in Alba, the fluorescent bunny rabbit. Glowing Genes is a highly informative, fascinating, and entertaining read about a burgeoning area of biotechnology that promises soon to revolutionize our world.

Glowing Genes

Author: Marc Zimmer
Publisher: Prometheus Books
ISBN: 1615922490
Format: PDF, Kindle
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Ranked 8th of 20 Best-Sellers in the Physiology 2005 Category compiled by YBP Library ServicesBioluminescence is a hot new subfield of biotechnology...Zimmer explains the science behind this...in a manner accessible to everyone. Even those who fear or avoid science books will enjoy it. In a creative and informal style, with touches of irony and humor, Zimmer easily imparts the sense of excitement displayed by researchers in this area.- Science & Theology News...an excellent biography of a molecule and a technology...a tale worth telling. It would make a great reference for student researchers, an independent reading assignment, or a source of excerpts with which to enrich biology teaching.- NSTA Recommends- Journal of College Science TeachingMany countermeasures currently being developed against chemical and biological threats posed by international terrorism rely directly or indirectly upon the discoveries described so elegantly in this book.- Keith B. Ward, Ph.D., Science Advisor and Program Manager, Homeland Security Advanced Research Projects Agency, U. S. Department of Homeland SecurityMarc Zimmer has written the first popular science book on an amazing new area of biotechnology that will help fight cancer, create new products, improve agriculture, and combat terrorism. For more than one hundred and sixty million years, green fluorescent protein has existed in one species of jellyfish. In 1994 it was cloned, giving rise to a host of useful and potentially revolutionary applications in biotechnology. Today researchers are using this ancient glowing protein to pursue exciting new discoveries, from tracking the process of bacterial infection to detecting chemical and biological agents planted by terrorists.A recognized expert in this field, Zimmer begins with an overview of the many uses of these glowing genes to kill and image cancer cells, monitor bacterial infections, and light up in the presence of pollution. He then discusses the biological reasons that glowing proteins first evolved in jellyfish and fireflies, and looks at the history of bioluminescence and the dedicated scientists who devoted their careers to explaining this phenomenon. The story of how glowing genes were located, cloned, and then mass-produced is in itself a fascinating tale.Zimmer next turns to the serious, and not-so-serious, uses of fluorescent proteins. In agriculture it may soon be possible to produce crops that signal dryness by glowing. In industry a red fluorescent protein originally found in corals may find a use in sheep as a substitute for environmentally harmful wool dyes.Furthermore, the glowing gene revolution has led to significantly more humane treatment of laboratory animals. No longer must animal lives be sacrificed to understand disease processes; now researchers can observe the spread of cancer and infections by treating animals with green fluorescent genes and similar proteins.In the fight against terrorism a glowing gene has been created that lights up in the presence of anthrax spores, chemical warfare agents, and landmines. And in a completely different arena, we have already seen the emergence of transgenic art in Alba, the fluorescent bunny rabbit.Glowing Genes is a highly informative, fascinating, and entertaining read about a burgeoning area of biotechnology that promises soon to revolutionize our world.Marc Zimmer, Ph.D., is the Christian A. Johnson Distinguished Teaching Professor and professor of chemistry at Connecticut College. His research has been funded by the National Institutes of Health, and he has published more than fifty scientific papers, mainly on the topic of bioluminescence.

Illuminating Disease

Author: Marc Zimmer
Publisher: Oxford University Press
ISBN: 0199362823
Format: PDF, Kindle
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Green fluorescent proteins have been floating in the ocean for more than 160 million years, but it took a curious scientist, fascinated by pinpricks of green light, to begin unlocking their potential. Now these jellyfish proteins have become one of the most important tools available to researchers in modern medicine and biology. By using them to illuminate other proteins that were previously invisible even under a microscope, scientists are now able to observe facets of disease that would have otherwise gone undetected. Green fluorescent proteins are used in over three million experiments a year and have proved invaluable for tasks such as tracking HIV, breeding bird flu-resistant chickens, and confirming the existence of cancerous stem cells. In Illuminating Disease, Marc Zimmer introduces us to these revolutionary proteins, acquainting readers both with the researchers responsible for the proteins' discovery as well as their wide utility. The book details the history of genetically modified fluorescent parasites and viruses, which provide scientists with lifesaving information about the spread of diseases. Green fluorescent proteins allow scientists and doctors to understand diseases better by quite literally illuminating various microscopic interactions occurring in living cells that otherwise would have gone unseen. The book is richly illustrated, showing the visually striking uses of green fluorescent proteins, and many of these scans have won awards in biological imaging competitions. An ideal introduction for students and advanced researchers alike, Illuminating Disease is an accessible yet deeply probing investigation into one of the most important developments in medical research of the last several decades.

Aglow in the Dark

Author: Vincent Pieribone
Publisher: Harvard University Press
ISBN: 9780674019218
Format: PDF, ePub
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Traces the history of green fluorescent protein from its discovery in the early 1960s to its current uses in the twenty-first century, and explores how the compound has changed the field of molecular biology.

Frankenstein s Cat

Author: Emily Anthes
Publisher: Oneworld Publications
ISBN: 1780742169
Format: PDF, ePub
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From the petri dish to the pet shop, meet the high-tech menagerie of the near future, as humans reinvent the animal kingdom Fluorescent fish that glow near pollution. Dolphins with prosthetic fins. Robot-armoured beetles that military handlers can send on spy missions. Beloved pet pigs resurrected from DNA. Scientists have already begun to create these high-tech hybrids to serve human whims and needs. What if a cow could be engineered to no longer feel pain – should we design a herd that would assuage our guilt over eating meat? Acclaimed science writer Emily Anthes travels round the globe to meet the fauna of the future, from the Scottish birthplace of Dolly the sheep and other clones to a ‘pharm’ for cancer-fighting chickens. Frankenstein’s Cat is an eye-opening exploration of weird science – and how we are playing god in the animal world.

The Biotech Century

Author: Jeremy Rifkin
Publisher:
ISBN: 9780575066588
Format: PDF, Kindle
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Arguing that the world is on the threshold of a revolution of unparalleled impact, this book makes an impassioned plea for awareness of the environmental, commercial and moral implications of the new biotechnology.

Genetic Engineering

Author: Mark Youngblood Herring
Publisher: Greenwood Publishing Group
ISBN: 9780313334733
Format: PDF
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Presents an overview of genetic engineering, detailing its history, its techniques, and its controversial application in the cloning of animals, modification of foods, genome mapping, DNA profiling, and treatment of disease.

Bioluminescence

Author: Thérèse Wilson
Publisher: Harvard University Press
ISBN: 0674071913
Format: PDF, ePub, Mobi
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Bioluminescence is everywhere on earth—most of all in the ocean, from angler fish in the depths to flashing dinoflagellates at the surface. Wilson and Hastings explore the natural history, evolution, and biochemistry of the diverse array of organisms that emit light and offer an evolutionary explanation for their sporadic distribution and rarity.

The Gene Revolution

Author: Sakiko Fukuda-Parr
Publisher: Earthscan
ISBN: 1844074102
Format: PDF, Docs
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Whether or not to embrace GM technologies is a fundamental and politically charged question facing humanity in the 21st century, particularly in light of rapidly growing populations and the unknown future impacts of climate change.The Gene Revolution is the first book to bridge the gap between the ?naysayers? and ?cheerleaders? and look at the issues and complexities facing developing and transitional countries over decisions about GM in light of the reality of what is happening on the ground. The first part of the volume looks at the rise of GM crops, commercialization and spread of the technology and the different positions of the USA and the European Union on the GM questionand the effect of global markets. The second part consists of country perspectives from Argentina, Brazil, China, India and South Africa, which provide insight into the profound challenges these countries face and the hard choices that have to be made. The final part takes the analysis a step further by comparing developing and transitional country experiences, and charts a future course for government policy on GM that supports growth, sustainability andequity for the many billions of people affected worldwide.

Cold Light

Author: Anita Sitarski
Publisher: Boyds Mills Press
ISBN: 9781590784686
Format: PDF
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This illuminating guide explores the science and wonder of cold light--the chemistry of animals and things that make light but not heat--by recounting the many stories of alchemist and chemist Robert Boyle who discovered this phenomenon in the seventeenth century.