GnRH The Master Molecule of Reproduction

Author: Andrea C. Gore
Publisher: Springer Science & Business Media
ISBN: 1475735650
Format: PDF, Mobi
Download Now
Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence. Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells. This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

Encyclopedia of Neuroscience

Author: Larry R. Squire
Publisher: Academic Press
ISBN: 0080963935
Format: PDF
Download Now
The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

Hormones and Reproduction of Vertebrates

Author: David O. Norris
Publisher: Academic Press
ISBN: 0080958095
Format: PDF, ePub, Docs
Download Now
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. * A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research. * Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction. * Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all. * Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them.

Neuropeptide GPCRs in neuroendocrinology

Author: Jae Young Seong
Publisher: Frontiers E-books
ISBN: 2889192679
Format: PDF, Mobi
Download Now
The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain.

Immunology of reproduction

Author: Rajesh K. Naz
Publisher: CRC
ISBN:
Format: PDF, ePub, Mobi
Download Now
Immunology of Reproduction is a comprehensive review that describes the latest developments in reproductive immunology. The book focuses on the broad areas of infertility, pregnancy loss, and immunocontraception. Specific topics covered within infertility include the significance of antisperm antibodies and the sperm antigens involved, cell-mediated immunity, pathogenesis of endometriosis, and reproductive immunology of HIV infection. The section on pregnancy loss describes the unique role that immunology plays during pregnancy, both in fetal survival as well as in fetal demise. The book's section on immunocontraception describes the latest status of anti-hCG birth control vaccine and the development of potential contraceptive vaccines based upon LHRH, FSH, sperm and zona pellucida antigens. Immunology of Reproduction is a must have reference volume for all scientists working in andrology, fertilization, and embryology. Clinical practitioners working in reproductive endocrinology and maternal-fetal medicine will find the volume indispensable.

Books in Print

Author:
Publisher:
ISBN:
Format: PDF, ePub, Docs
Download Now
Books in print is the major source of information on books currently published and in print in the United States. The database provides the record of forthcoming books, books in-print, and books out-of-print.