Handbook of Nanotoxicology Nanomedicine and Stem Cell Use in Toxicology

Author: Saura C. Sahu
Publisher: John Wiley & Sons
ISBN: 1118855868
Format: PDF, ePub, Mobi
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The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Handbook of Nanotoxicology Nanomedicine and Stem Cell Use in Toxicology

Author: Daren Toure (Dr)
Publisher:
ISBN: 9781680952803
Format: PDF, ePub, Mobi
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Nanotoxicology is the study of the toxicity of nanomaterials. Because of quantum size effects and large surface area to volume ratio, nanomaterials have unique properties compared with their larger counterparts. Nanomedicine is the medical application of nanotechnology. nanomedicine ranges from the medical applications of nanomaterials, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology. The book "Handbook of Nanotoxicology, Nanomedicine and Stem Cell use in Toxicology" is consists of ten chapters. Cancer stem cells are defined as cancer cells that show the two properties of stemness that is unlimited self-renewal and, pluripotency or multipotency, which are broadly discussed in first chapter. In second chapter, we focus on the differentiation of ESCs into the ectodermal lineage and on the two in 2012 ongoing clinical trials involving transplantation of ESCs derivate into eye and spinal cord. We introduce the clarification for the progress and drawbacks of current cardiac stem cell therapy in third chapter. It finally indicates the future directions of cardiac cell therapy through our recent researchers combining PSCs and cell sheet technology. Induced pluripotent stem (iPS) cells are somatic cells which have been imbued with pluripotent differentiation potential through some form of artificial treatment in fourth chapter. We review studies that have examinied the epigenetic instability of ES cells during generation and maintenance cultures, and discuss the candidate factors that may be responsible for this epigenetic instability in fifth chapter. Crucial ignored parameters on nanotoxicology have been introduced in sixth chapter. Stem cell predictive hemotoxicology has been discussed in seventh chapter. In eight chapter, we introduce an exogenous regulators into embryonic stem cells. The application of embryonic stem (ES) cells to research and therapy has been a landmark development in science. The purpose of ninth chapter is in threefold: first, to examine the medical issues surrounding the cryopreservation of frozen embryos; second, to give an ethical analysis of the arguments for and against allowing to die: and thurd, to give recommendations on how to avoid the continuation of this problem in the future. Last chapter focuses on challenges and possibilities of embryonic stem cells for therapies. The successful establishment of human embryonic stem cells (HESCs) in culture has raised unprecedented public interest and expectation of treating intractable diseases such as diabetes, spinal cord injuries, neurodegenerative and cardiovascular diseases.

Stem Cells in Birth Defects Research and Developmental Toxicology

Author: Theodore P. Rasmussen
Publisher: John Wiley & Sons
ISBN: 1119283221
Format: PDF, Docs
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This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders. Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives

The Nanotechnology Revolution

Author: Dale A. Stirling
Publisher: CRC Press
ISBN: 1351617230
Format: PDF, Docs
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Nanotechnology is changing the world in a very big way, but at the atomic and sub-atomic level. Although the roots of nanotechnology can be traced back to more than a century ago, the last three decades have witnessed an explosion of nano-based technologies and products. This reference work examines the history, current status, and future directions of nanotechnology through an exhaustive search of the technical and scientific literature. The more than 4000 bibliographic citations it includes are carefully organized into core subject areas, and a geographic and subject index allows readers to quickly locate documents of interest. Although a sense of the global reach and interest in nanotechnology can be gleaned from the reference sections of countless journal articles, conference papers, and books, this is the only reference work providing an in-depth global perspective that is ready-made for nanotechnology professionals and those interested in learning more about all things nanotechnology. Despite the abundance of online resources, there is still an urgent need for well-researched, well-presented, concise, and thematically organized reference works. Instead of relying on wiki pages, citation aggregators, and related websites, the author searched the databases and databanks of scholarly literature search providers such as EBSCO, ProQuest, PUBMED, STN International, and Thomson Reuters. In addition, he used select serials-related databases to account for pertinent documents from countries in which English is not the primary national language (i.e., China Online Journals, e-periodica, J-STAGE, and SciELO Brazil among others).

Nanomaterials in Plants Algae and Microorganisms

Author: Durgesh Kumar Tripathi
Publisher: Academic Press
ISBN: 0128116463
Format: PDF, Mobi
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Nanomaterials in Plants, Algae and Microorganisms: Concepts and Controversies: Volume One discusses the vast amount of nanomaterials that have been released into the environment in a relatively short amount of time. There is a need to understand what the implications to the health of our biota and ecosystems are as the earth is increasingly inundated with these materials. Not all of the effects are negative, but their impacts are increasing exponentially due to their size, quantity and other factors. Covers the issues of nanoparticles on more simple organisms and their ecosystems Presents issues that are specific to terrestrial ecosystems Contains contributions from global experts who help increase understanding at the physiological, biochemical, molecular, and even genomic and proteomic levels Provides a critical assessment of the progress taking place on this topic and sheds light on future research needs

The Handbook of Nanomedicine

Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493969668
Format: PDF, Docs
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Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.

Haschek and Rousseaux s Handbook of Toxicologic Pathology

Author: Wanda M. Haschek
Publisher: Academic Press
ISBN: 0124157653
Format: PDF, Kindle
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Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Handbook of Personalized Medicine

Author: Ioannis S. Vizirianakis
Publisher: CRC Press
ISBN: 9814411191
Format: PDF, ePub, Mobi
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This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Nanotechnology and Nanomedicine in Diabetes

Author: Lan-Anh Le
Publisher: CRC Press
ISBN: 1466505087
Format: PDF, ePub
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Understanding the importance of nanosciences in diabetes is problematic as some texts can be too technical for the novice. This book uses a reader–friendly format suitable not only for practitioners but newcomers as well. It begins with general aspects of nanotechnology and nanomedicine in diabetes. It then discusses glucose and glucose sensors based on functional nanocomposites before moving on to a discussion of insulin and the use of nanoprobes to monitor cell processes in the pancreas. Finally, it explores drugs and other treatments, including second-generation sulfonylurea glipizide loaded biodegradable nanoparticles and nanoparticle-mediated delivery of angiogenic inhibitors in diabetic retinopathy.

Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine Chemistry and Engineering

Author: Soni, Shivani
Publisher: IGI Global
ISBN: 1466663642
Format: PDF, ePub
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As a paradigm for the future, micro-scale technology seeks to fuse revolutionary concepts in science and engineering and then translate it into reality. Nanotechnology is an interdisciplinary field that aims to connect what is seen with the naked eye and what is unseen on the molecular level. The Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering examines the strengths and future potential of micro-scale technologies in a variety of industries. Highlighting the benefits, shortcomings, and emerging perspectives in the application of nano-scale technologies, this book is a comprehensive reference source for synthetic chemists, engineers, graduate students, and researchers with an interest in the multidisciplinary applications, as well as the ongoing research in the field.