Handbook of Single Molecule Biophysics

Author: Peter Hinterdorfer
Publisher: Springer Science & Business Media
ISBN: 9780387764979
Format: PDF, Docs
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This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Handbook of Single Molecule Fluorescence Spectroscopy

Author: Chris Gell
Publisher: Oxford University Press on Demand
ISBN: 0198529422
Format: PDF, Mobi
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This is a practical introduction to single molecule fluorescence experiments, the analysis of the data, and applications of the techniques to the study of biological structure and function.

Handbook of Molecular Biophysics

Author: Henrik G. Bohr
Publisher: John Wiley & Sons
ISBN: 3527407022
Format: PDF, Mobi
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This handbook and reference condenses the biophysics contents of the renowned Encyclopedia of Applied Physics in one handy volume. Twenty-eight carefully written overview articles cover the latest research, including single molecule spectroscopy, biosensors and cellular biomechanics. Readers benefit from concise summaries of the fundamentals, methods and applications, backed by detailed tables of contents for quick access, and glossaries of terms, as well as detailed lists of references and further reading. For libraries and research and development teams in academia and industry. From the contents: Quantum Mechanics Methods for Molecular Biophysics and Electronic Structure Calculations of Biomolecules Studies of Motions of Biomolecules and Molecular Dynamics Calculations Biomolecular Structures and Dynamics in Proteins, Lipids, and DNA Radiation and Spectroscopy Methods in Molecular Biophysics Neurobiophysics and Ion Channels Techniques for Detecting Molecular Structures down to the Single Molecule Level Physical Effects in Biomolecules and larger Organic Systems Molecular Biophysics Applications in Medicine

Handbook of Molecular Force Spectroscopy

Author: Aleksandr Noy
Publisher: Springer Science & Business Media
ISBN: 038749989X
Format: PDF, Docs
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Researchers in academia and industry who are interested in techniques for measuring intermolecular forces will find this an essential text. It presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The handbook begins with a review of the fundamental physics of loading single and multiple chemical bonds on the nanometer scale. It contains a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is also addressed.

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics

Author: Susanta K Sarkar
Publisher: Morgan & Claypool Publishers
ISBN: 1681741806
Format: PDF, Docs
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This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.

Single Molecule Biophysics

Author: Tamiki Komatsuzaki
Publisher: John Wiley & Sons
ISBN: 111813138X
Format: PDF, Docs
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Discover the experimental and theoretical developments inoptical single-molecule spectroscopy that are changing the ways wethink about molecules and atoms The Advances in Chemical Physics series provides thechemical physics field with a forum for critical, authoritativeevaluations of advances in every area of the discipline. Thislatest volume explores the advent of optical single-moleculespectroscopy, and how atomic force microscopy has empowered novelexperiments on individual biomolecules, opening up new frontiers inmolecular and cell biology and leading to new theoreticalapproaches and insights. Organized into two parts—oneexperimental, the other theoretical—this volume exploresadvances across the field of single-molecule biophysics, presentingnew perspectives on the theoretical properties of atoms andmolecules. Single-molecule experiments have provided freshperspectives on questions such as how proteins fold to specificconformations from highly heterogeneous structures, how signaltransductions take place on the molecular level, and how proteinsbehave in membranes and living cells.This volume is designed tofurther contribute to the rapid development of single-moleculebiophysics research. Filled with cutting-edge research reported in a cohesive mannernot found elsewhere in the literature, each volume of theAdvances in Chemical Physics series serves as the perfectsupplement to any advanced graduate class devoted to the study ofchemical physics.

Relativistische Quantenmechanik

Author: Armin Wachter
Publisher: Springer-Verlag
ISBN: 3540274847
Format: PDF, Mobi
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- Welche Probleme tauchen in relativistischen Erweiterungen der Schrödinger-Theorie auf, insbesondere wenn man an der gewohnten Ein-Teilchen-Wahrscheinlichkeitsinterpretation festhält? - Inwieweit können diese Schwierigkeiten überwunden werden? - Worin besteht die physikalische Notwendigkeit von Quantenfeldtheorien? Viele Bücher geben auf solch fundamentale Verständnisfragen nur unzureichend Antwort, indem sie das relativistisch-quantenmechanische Ein-Teilchenkonzept zugunsten einer möglichst frühen Einführung der Feldquantisierung relativ schnell abhandeln oder ganz weglassen. Im Gegensatz dazu betont das vorliegende Lehrbuch gerade diesen Ein-Teilchenaspekt (relativistische Quantenmechanik ‚im engeren Sinne’), diskutiert die damit einhergehenden Probleme und motiviert somit auf physikalisch verständliche Weise die Notwendigkeit quantisierter Felder. Die ersten beiden Kapitel beschäftigen sich mit der ausführlichen Darlegung und Gegenüberstellung der Klein-Gordon- und Dirac-Theorie - immer mit Blick auf die nichtrelativistische Theorie. Im dritten Kapitel werden relativistische Streuprozesse behandelt und die Feynman-Regeln aus Propagatorverfahren heraus entwickelt. Dabei wird auch hier deutlich, warum man letztlich um eine quantenfeldtheoretische Begründung nicht herumkommt. Dieses Lehrbuch wendet sich an alle Studierenden der Physik, die an einer übersichtlich geordneten Darstellung der relativistischen Quantenmechanik ‚im engeren Sinne’ und deren Abgrenzung zu Quantenfeldtheorien interessiert sind.

Single Particle Tracking and Single Molecule Energy Transfer

Author: Christoph Bräuchle
Publisher: John Wiley & Sons
ISBN: 9783527628377
Format: PDF, ePub
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Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.

Single Molecule Cellular Biophysics

Author: Mark C. Leake
Publisher: Cambridge University Press
ISBN: 1139619349
Format: PDF, ePub
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Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the physical and life sciences. Mathematical derivations are kept to a minimum whilst unnecessary biological terminology is avoided and text boxes provide readers from either background with additional information. 100 end-of-chapter exercises are divided into those aimed at physical sciences students, those aimed at life science students and those that can be tackled by students from both disciplines. The use of case studies and real research examples make this textbook indispensable for undergraduate students entering this exciting field.

Biophysik

Author: Rodney Cotterill
Publisher: John Wiley & Sons
ISBN: 9783527406869
Format: PDF, ePub, Docs
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Was eignet sich besser zum Einstieg in ein neues Fachgebiet als ein in der Muttersprache verfasster Text? So manch angehender Biophysiker hätte sich den englischen 'Biophysics' von Cotterill schon lange als deutsche Übersetzung gewünscht. Hier ist sie: sorgfältig strukturiert und ausgewogen wie das englische Original, mit dem Vorzug der schnelleren Erfaßbarkeit. Vom Molekül bis zum Bewusstsein deckt der "Cotterill" alle Ebenen ab. Er setzt nur wenig Grundwissen voraus und ist damit für die Einführungsvorlesung nach dem Vordiplom ideal. Zusätzliche Anhänge mit mathematischen und physikalischen Grundlagen machen das Lehrbuch auch für Chemiker und Biologen attraktiv.