Handbook of Single Molecule Biophysics

Author: Peter Hinterdorfer
Publisher: Springer Science & Business Media
ISBN: 9780387764979
Format: PDF
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This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Handbook of Single Molecule Fluorescence Spectroscopy

Author: Chris Gell
Publisher: Oxford University Press on Demand
ISBN: 0198529422
Format: PDF
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This is a practical introduction to single molecule fluorescence experiments, the analysis of the data, and applications of the techniques to the study of biological structure and function.

Handbook of Molecular Biophysics

Author: Henrik G. Bohr
Publisher: John Wiley & Sons
ISBN: 3527407022
Format: PDF, Kindle
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This handbook and reference condenses the biophysics contents of the renowned Encyclopedia of Applied Physics in one handy volume. Twenty-eight carefully written overview articles cover the latest research, including single molecule spectroscopy, biosensors and cellular biomechanics. Readers benefit from concise summaries of the fundamentals, methods and applications, backed by detailed tables of contents for quick access, and glossaries of terms, as well as detailed lists of references and further reading. For libraries and research and development teams in academia and industry. From the contents: Quantum Mechanics Methods for Molecular Biophysics and Electronic Structure Calculations of Biomolecules Studies of Motions of Biomolecules and Molecular Dynamics Calculations Biomolecular Structures and Dynamics in Proteins, Lipids, and DNA Radiation and Spectroscopy Methods in Molecular Biophysics Neurobiophysics and Ion Channels Techniques for Detecting Molecular Structures down to the Single Molecule Level Physical Effects in Biomolecules and larger Organic Systems Molecular Biophysics Applications in Medicine

Handbook of Molecular Force Spectroscopy

Author: Aleksandr Noy
Publisher: Springer Science & Business Media
ISBN: 038749989X
Format: PDF, ePub
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Researchers in academia and industry who are interested in techniques for measuring intermolecular forces will find this an essential text. It presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The handbook begins with a review of the fundamental physics of loading single and multiple chemical bonds on the nanometer scale. It contains a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is also addressed.

Handbook of Fluorescence Spectroscopy and Imaging

Author: Markus Sauer
Publisher: John Wiley & Sons
ISBN: 3527633529
Format: PDF, Docs
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Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence imaging. Examples show how each technique can help in obtaining detailed and refined information from individual molecular systems.

Handbook of Single Molecule Electronics

Author: Kasper Moth-Poulsen
Publisher: CRC Press
ISBN: 9814463396
Format: PDF, Mobi
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Single-molecule electronics has evolved as a vibrant research field during the last two decades. The vision is to be able to create electronic components at the highest level of miniaturization—the single molecule. This book compiles and details cutting-edge research with contributions from chemists, physicists, theoreticians, and engineers. It covers all aspects of single-molecule electronics, from the theory through experimental realizations and the chemical synthesis of molecular components to the implementation of molecular components in future integrated circuits. This book describes in detail both established methods and recent advances in the field, including vibrational effects, switching phenomena, quantum interference, thermal power, and parallel assembly strategies. The authors add more details to the chapters than typically found in the primary literature so that the book can be read not only by specialists but also by non-experts and students with an interest in the research field. Each chapter is accompanied by problems, and a solutions manual is also provided.

Single Molecule Metal Induced Energy Transfer

Author: Narain Karedla
Publisher: Springer
ISBN: 3319605372
Format: PDF, Kindle
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This thesis presents a novel single-molecule spectroscopy method that, for the first time, allows the dipole orientations and fluorescence lifetimes of individual molecules to be measured simultaneously. These two parameters are needed to determine the position of individual molecules with nanometer accuracy near a metallic structure. Proof-of-principle experiments demonstrating the value of this new single-molecule localization concept are also presented. Lastly, the book highlights potential applications of the method in biophysics, molecular physics, soft matter and structural biology.

Single Particle Tracking and Single Molecule Energy Transfer

Author: Christoph Bräuchle
Publisher: John Wiley & Sons
ISBN: 9783527628377
Format: PDF, ePub, Docs
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Closing a gap in the literature, this handbook gathers all the information on single particle tracking and single molecule energy transfer. It covers all aspects of this hot and modern topic, from detecting virus entry to membrane diffusion, and from protein folding using spFRET to coupled dye systems, as well recent achievements in the field. Throughout, the first-class editors and top international authors present content of the highest quality, making this a must-have for physical chemists, spectroscopists, molecular physicists and biochemists.

Biomolecular Kinetics

Author: Clive R. Bagshaw
Publisher: CRC Press
ISBN: 1351646664
Format: PDF, Mobi
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"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.

Single Molecule Spectroscopy

Author: R. Rigler
Publisher: Springer Science & Business Media
ISBN: 3642565441
Format: PDF, Mobi
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The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.