Handbook of Stress and the Brain

Author: T. Steckler
Publisher: Elsevier Science Limited
ISBN: 9780444518224
Format: PDF
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The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. Part 2 treats the complexity of short-term and long-term regulation of stress responsivity, the role of stress in psychiatric disorders as based on both preclinical and clinical evidence, and the current status with regard to new therapeutic strategies targetting stress-related disorders. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms

Handbook of Stress and the Brain Part 1 The Neurobiology of Stress

Author: Thomas Steckler
Publisher: Elsevier
ISBN: 0080553249
Format: PDF, Mobi
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The Handbook of Stress and the Brain focuses on the impact of stressful events on the functioning of the central nervous system; how stress affects molecular and cellular processes in the brain, and in turn, how these brain processes determine our perception of and reactivity to, stressful challenges - acutely and in the long-run. Written for a broad scientific audience, the Handbook comprehensively reviews key principles and facts to provide a clear overview of the interdisciplinary field of stress. The work aims to bring together the disciplines of neurobiology, physiology, immunology, psychology and psychiatry, to provide a reference source for both the non-clinical and clinical expert, as well as serving as an introductory text for novices in this field of scientific inquiry. Part 1 addresses basic aspects of the neurobiology of the stress response including the involvement of neuropeptide, neuroendocrine and neurotransmitter systems and its corollaries regarding gene expression and behavioural processes such as cognition, motivation and emotionality. * Provides an overview of recent advances made in stress research * Includes timely discussion of stress and its effect on the immune system * Presents novel treatment strategies targeting brain processes involved in stress processing and coping mechanisms

Stress Neuroendocrinology and Neurobiology

Author: George Fink
Publisher: Academic Press
ISBN: 0128024232
Format: PDF, Kindle
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Stress: Neuroendocrinology and Neurobiology: Handbook of Stress Series, Volume 2, focuses on neuroendocrinology, the discipline that deals with the way that the brain controls hormonal secretion, and in turn, the way that hormones control the brain. There have been significant advances in our understanding of neuroendocrine molecular and epigenetic mechanisms, especially in the way in which stress-induced hormonal and neurochemical changes affect brain plasticity, neuronal connectivity, and synaptic function. The book features the topic of epigenetics, and how it enables stress and other external factors to affect genetic transmission and expression without changes in DNA sequence. Integrated closely with new behavioral findings and relevance to human disorders, the concepts and data in this volume offer the reader cutting-edge information on the neuroendocrinology of stress. Volume 2 is of prime interest to neuroscientists, clinicians, researchers, academics, and graduate students in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry, and in some areas of the social sciences, including stress and its management in the workplace. Includes chapters that offer impressive scope with topics addressing the neuroendocrinology and endocrinology of stress Presents articles carefully selected by eminent stress researchers and prepared by contributors that represent outstanding scholarship in the field Richly illustrated, with explanatory figures and tables

Fundamental Neuroscience

Author: Larry R. Squire
Publisher: Academic Press
ISBN: 0123858704
Format: PDF, ePub, Mobi
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Fundamental Neuroscience, 3rd Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts. A companion web site contains test questions, and an imagebank of the figures for ready use in presentations, slides, and handouts. Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! New to this edition: * 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness * Companion website with figures, web links to additional material, and test questions * Additional text boxes describing key experiments, disorders, methods, and concepts * Multiple model system coverage beyond rats, mice, and monkeys * Extensively expanded index for easier referencing

Abnormal Psychology An Integrative Approach

Author: David H. Barlow
Publisher: Cengage Learning
ISBN: 1337514047
Format: PDF, ePub
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Balancing biological, psychological, social, and cultural approaches, this book's ground-breaking integrative approach is the most modern, scientifically valid method for studying abnormal psychology. Updated with leading-edge research findings, the eighth edition draws on the expertise of David H. Barlow, V. Mark Durand, and Stefan G. Hofmann, three internationally recognized experts in clinical psychology. In ABNORMAL PSYCHOLOGY: AN INTEGRATIVE APPROACH, the authors successfully blend sophisticated research with an accessible, engaging writing style. They go beyond simply describing different schools of thought on psychological disorders, exploring the interactions of the various forces that contribute to psychopathology. This comprehensive resource includes integrated case studies (95 percent from the authors' own files) and additional study tools. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

New Horizons in Health

Author: Board on Behavioral, Cognitive, and Sensory Sciences
Publisher: National Academies Press
ISBN: 0309072964
Format: PDF, Docs
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New Horizons in Health discusses how the National Institutes of Health (NIH) can integrate research in the social, behavioral, and biomedical sciences to better understand the causes of disease as well as interventions that promote health. It outlines a set of research priorities for consideration by the Office of Behavioral and Social Sciences Research (OBSSR), with particular attention to research that can support and complement the work of the National Institutes of Health. By addressing the range of interactions among social settings, behavioral patterns, and important health concerns, it highlights areas of scientific opportunity where significant investment is most likely to improve national—and global—health outcomes. These opportunities will apply the knowledge and methods of the behavioral and social sciences to contemporary health needs, and give attention to the chief health concerns of the general public.

Treatment for Posttraumatic Stress Disorder in Military and Veteran Populations

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309301769
Format: PDF, Kindle
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Posttraumatic stress disorder (PTSD) is one of the signature injuries of the U.S. conflicts in Afghanistan and Iraq, but it affects veterans of all eras. It is estimated that 7-20% of service members and veterans who served in Operation Enduring Freedom and Operation Iraqi Freedom may have the disorder. PTSD is characterized by a combination of mental health symptoms - re-experiencing of a traumatic event, avoidance of trauma-associated stimuli, adverse alterations in thoughts and mood, and hyperarousal - that last at least 1 month and impair functioning. PTSD can be lifelong and pervade all aspects of a service member's or veteran's life, including mental and physical health, family and social relationships, and employment. It is often concurrent with other health problems, such as depression, traumatic brain injury, chronic pain, substance abuse disorder, and intimate partner violence. The Department of Defense (DoD) and the Department of Veterans Affairs (VA) provide a spectrum of programs and services to screen for, diagnose, treat for, and rehabilitate service members and veterans who have or are at risk for PTSD. The 2010 National Defense Authorization Act asked the Institute of Medicine to assess those PTSD programs and services in two phases. The Phase 1 study, Treatment for Posttraumatic Stress Disorder in Military and Veteran Populations: Initial Assessment, focused on data gathering. Treatment for Posttraumatic Stress Disorder in Military and Veteran Populations Final Assessment is the report of the second phase of the study. This report analyzes the data received in Phase 1 specifically to determine the rates of success for each program or method. Treatment for Posttraumatic Stress Disorder in Military and Veteran Populations Final Assessment considers what a successful PTSD management system is and whether and how such a system is being implemented by DoD and VA. This includes an assessment of what care is given and to whom, how effectiveness is measured, what types of mental health care providers are available, what influences whether a service member or veteran seeks care, and what are the costs associated with that care. This report focuses on the opportunities and challenges that DoD and VA face in developing, implementing, and evaluating services and programs in the context of achieving a high-performing system to care for service members and veterans who have PTSD. The report also identifies where gaps or new emphases might be addressed to improve prevention of, screening for, diagnosis of, and treatment and rehabilitation for the disorder. The findings and recommendations of Treatment for Posttraumatic Stress Disorder in Military and Veteran Populations: Final Assessment will encourage DoD and VA to increase their efforts in moving toward a high-performing, comprehensive, integrated PTSD management strategy that addresses the needs of current and future service members, veterans, and their families.

Genes Memes Culture and Mental Illness

Author: Hoyle Leigh
Publisher: Springer Science & Business Media
ISBN: 9781441956712
Format: PDF, Mobi
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What produces mental illness: genes, environment, both,neither? The answer can be found in memes—replicable units of information linking genes and environment in the memory and in culture—whose effects on individual brain development can be benign or toxic. This book reconceptualizes mental disorders as products of stressful gene-meme interactions and introduces a biopsychosocial template for meme-based diagnosis and treatment. A range of therapeutic modalities, both broad-spectrum (meditation) and specific(cognitive-behavioral), for countering negative memes and their replication are considered, as are possibilities for memetic prevention strategies. In this book, the author outlines the roles of genes and memes in the evolution of the human brain; elucidates the creation, storage, and evolution of memes within individual brains; examines culture as a carrier and supplier of memes to the individual; provides examples of gene-meme interactions that can result in anxiety, depression, and other disorders; proposes a multiaxial gene-meme model for diagnosing mental illness; identifies areas of meme-based prevention for at-risk children; and defines specific syndromes in terms of memetic symptoms, genetic/ memetic development, and meme-based treatment.

The Scientific Basis of Integrative Medicine Second Edition

Author: Leonard A. Wisneski
Publisher: CRC Press
ISBN: 9781420082906
Format: PDF, Docs
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Since the first suffering supplicant offered a prayer to his god or the first mother cradled an ailing child in her caring arms, we have witnessed how human health and healing goes beyond any inventory of parts and infusion of chemicals. We humans are a complex melding of thought, emotion, spirit, and energy and each of those components is as critical to our well-being as our physiological status. Even if we are just beginning to quantify and document these seemingly intangible aspects, to ignore them in the practice of medicine is neglect and an invitation to do harm. Now in its second edition, The Scientific Basis of Integrative Medicine continues to provide doctors and other health practitioners with information on complementary and alternative approaches to health, that is authoritative, scientifically based, and epidemiologically substantiated. Written for doctors and healthcare professionals by pioneering practitioners and updated with the newest research across an increasing range of possibilities, the new edition of this bestselling work – Establishes the scientific basis for the mind–body connection and then documents the puissant interactions of the endocrine, immune, nervous, and stress systems that so profoundly influence our lives Examines that healing dimension of spirituality, which informs but transcends the five senses Investigates how hope, faith, and love aid healing Discusses how the emotional presence of a practitioner affects patient outcome Considers the incorporation of a unified theory that can account for the existence of health enhancing energy fields within — as well as outside — the human body Integral physiology serves as a bridge between Western medical knowledge and the equally valuable, but less well-recognized, Eastern systems of medicine. The authors refer to it as integrative because it combines important Western biological knowledge with forms of healing that incorporate the mental and emotional, and spiritual aspects that are essential to health, because those aspects are what make us essentially human.