Hormones Genes and Cancer

Author: Brian E. Henderson
Publisher: Oxford University Press
ISBN: 0199771588
Format: PDF, Docs
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Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic factors influence hormone-related cancer risk? Hormones, Genes, and Cancer addresses these questions. Over the past few decades, cancer research has focused on external environmental causes(e.g., tobacco smoke, viruses, asbestos). With the advent of new genetic sequencing techniques, we are just now beginning to understand how the body's internal environment(i.e., the hormones and growth factors that determine normal development) influences cancer etiology and prevention. From molecular insights to clinical analyses, this volume provides state-of-the-art information on the complex interactions between hormones and genes and cancer. The epidemiology and molecular endocrinology of prostate, breast, uterine, ovarian and testicular cancer are detailed in this timely treatise.

Genes Oncogenes and Hormones

Author: Robert B. Dickson
Publisher: Springer Science & Business Media
ISBN: 146153500X
Format: PDF
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Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current di agnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

Therapeutic Resistance to Anti hormonal Drugs in Breast Cancer

Author: Stephen Hiscox
Publisher: Springer Science & Business Media
ISBN: 1402085265
Format: PDF, Mobi
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One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these therapeutic constraints and that drug resistance may further impinge on tumour cell functions that may ultimately promote an adverse cell phenotype. New targets have been identified with potential therapeutic applications in resistant breast cancer leading to the subsequent evaluation of inhibitors of these targets in preclinical studies. Importantly, there is increasing evidence from such studies demonstrating the benefit of novel combination strategies as potential avenues for future drug regimens. Written by experts in the subject area, this book covers the molecular details and functional consequences of endocrine resistance in breast cancer with particular emphasis on the future applications of novel drug combinations that may be utilized to circumvent resistance and improve anti-tumour effects. This book represents a timely publication in the field of breast cancer research, providing current knowledge in the area of drug resistance and will be important reading material for clinicians and researchers alike.

Hormones and Vitamins in Cancer Treatment

Author: Aurel Lupulescu
Publisher: CRC Press
ISBN: 9780849359736
Format: PDF, ePub
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Hormones and Vitamins in Cancer Treatment is intended to serve as a therapeuticial guide for physicians using non-aggressive methods, such as hormonotherapy and vitamin therapy, when treating cancer patients. This book provides the rationale and scientific basis for hormones and vitamins, which play an important role in cancer management, and emphasizes the significance of hormones and vitamins in chemoprevention and chemoprophylaxis of cancer. Topics discussed in this book include the criteria for selecting patients for hormonotherapy and vitamin therapy; the favorable effects and advantages of hormonotherapy and vitamin therapy over (or used as adjuvant therapeutic agents) more aggressive methods, such as chemotherapy, radiation therapy, immunotherapy or surgery; and hormone-like substances, such as growth factors, interferons, interleukins, and prostoglandins. Also included is the newest information regarding the role of diet in cancer prevention. This book is packed with valuable information for researchers, physicians, and students of endrocrinology and clinical oncology. It is also the only book of its kind that discusses the role of hormones, hormone-like substances, and vitamins in cancer prevention and treatment.

Medical Sciences E Book

Author: Jeannette Naish
Publisher: Elsevier Health Sciences
ISBN: 0702052493
Format: PDF, Docs
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An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences is designed to do the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context. . An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences does the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context. Eleven new contributors. Completely new chapters on Biochemistry and cell biology, Genetics, The nervous system, Bones, muscle and skin, Endocrine and reproductive systems, The cardiovascular system, The renal system and Diet and nutrition. Completely revised and updated throughout with over 35 new illustrations . Expanded embryology sections with several new illustrations.

Medical and Psychosocial Care of the Cancer Survivor

Author: Kenneth D. Miller
Publisher: Jones & Bartlett Publishers
ISBN: 1449617980
Format: PDF, Mobi
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This ground-breaking clinical reference provides a comprehensive perspective of the multiple issues facing cancer survivors, ranging from early post-treatment through long-term care. Clear, clinically practical chapters written by experts in the field concentrate on multi-dimensional issues that confront cancer survivors. Divided into four, focused sections—overview of survivorship, medical care, psychosocial care, and epidemiologic—this book is evidence-based and uses case examples and illustrations throughout to add to the understanding of the material and its application to the individual patient. Primary care physicians, nurses, oncologists, hematologists, students of medicine, and survivorship researchers will all find this to be a valuable asset in setting the standard of care in the field of cancer survivorship.

Endocrine Therapies in Breast Cancer

Author: Aman U. Buzdar
Publisher: Oxford University Press
ISBN: 0199218145
Format: PDF, ePub, Mobi
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Breast cancer is one of the leading causes of cancer mortality in women worldwide, and the risk of disease recurrence continues despite improvements in screening and treatment. For patients with hormone receptor-positive breast cancer, some form of endocrine therapy is central to the management of their disease. Tamoxifen has long been the mainstay of endocrine therapy in this group of patients. However, there is mounting evidence showing that the aromatase inhibitors are able to reduce overall oestrogen levels and appear to be better tolerated over a long term than tamoxifen. New and emerging indications for the aromatase inhibitors are providing clinicans (and patients) with alternative treatment options with differing side effect profiles. Part of the Oxford Oncology Library, this pocketbook will summarise the latest evidence-based and practical information on the use of endrocrine therapies in the management of breast cancer (early stage, metastatic disease, and prevention of disease). With contributions from leading oncologists from the MD Anderson Cancer Center, the book covers the range of endocrine therapies currently available to clinicians including ovarian ablation, anti-estrogens, aromatase inhibitors, fulvestrant, progestins, androgens, and combination endocrine and chemotherapy. The book also includes useful chapters on the identification and optimal selection of patients for endocrine therapy as well as the role of endocrine treatments in the prevention of breast cancer. This book will serve as an invaluable reference for all health care professionals involved in the management of patients with breast cancer.

Stress and Your Health

Author: Hymie Anisman
Publisher: John Wiley & Sons
ISBN: 1118850335
Format: PDF, ePub, Docs
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Stress and Your Health: From Vulnerability to Resilience presents an evidence-based evaluation of the various effects of stress, along with methods to alleviate distress and stress-related illnesses. Examines myriad stressor effects and proven ways to alleviate stress in our lives Covers a wide range of stressor-related topics including therapeutic strategies to deal with stress and factors that hinder treatment of stress Makes difficult biochemical and immunological concepts accessible to a non-specialist audience Addresses many of the factors that cause individuals to be more vulnerable to the impact of stressors and at increased risk for pathology

Clinical Companion for Medical Surgical Nursing E Book

Author: Donna D. Ignatavicius
Publisher: Elsevier Health Sciences
ISBN: 1455772577
Format: PDF, Kindle
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The Clinical Companion for Ignatavicius & Workman: Medical-Surgical Nursing: Patient-Centered Collaborative Care, 7th Edition, is an easy-to-use, A-Z guide to 245 common medical-surgical conditions and their management. Written in a reader-friendly, direct-address style, this handbook is a convenient quick reference that you can carry with you on clinical days. A-Z synopses of 245 diseases and disorders, along with related collaborative care, serve as both a quick reference for clinical days and a study resource for essential information Streamlined format helps you focus more effectively on nursing care priorities Consistent collaborative care format helps you prepare for clinical days more efficiently. Special Considerations highlights call your attention to important aspects of nursing care, such as Genetic/Genomic Considerations, Considerations for Older Adults, Women's Health Considerations, and Cultural Considerations. National Patient Safety Goals (NPSG) icons help you provide safe and effective care by highlighting safety information identified in The Joint Commission's National Patient Safety Goals. Concepts of Medical-Surgical Nursing sections provide a quick, one-stop review of eight concepts that are critical to medical-surgical nursing practice. A-Z thumb tabs along the edges of the pages facilitate quick access to clinical information for just-in-time learning and review at the bedside. 10 quick-reference appendices provide need-to-know, quick-reference coverage of common or important clinical topics Guide to Head-To-Toe Physical Assessment of Adults Terminology Associated With Fluid and Electrolyte Balance Laboratory Values Interventions for Common Environmental Emergencies Chemical and Biological Agents of Terrorism Discharge Planning Electrocardiographic Complexes, Segments, and Intervals The Patient Requiring Intubation and Mechanical Ventilation The Patient Requiring Chest Tubes Communication Quick Reference for Spanish-Speaking Patients Updated content matches the Ignatavicius & Workman textbook for a reliably seamless reference and study experience. UNIQUE! Nursing Safety Priorities highlights have been refined and divided into three types of Nursing Safety Priority highlights: Drug Alert!, Critical Rescue!, and Action Alert! to help you recognize critical situations in which the patient's health or very life may be in jeopardy. Increased use of color improves table readability and highlights headings and new Nursing Safety Priority boxes.

The Philadelphia Chromosome

Author: Jessica Wapner
Publisher: The Experiment
ISBN: 1615191658
Format: PDF, ePub, Mobi
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Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.