Image and Reality

Author: Alan J. Rocke
Publisher: University of Chicago Press
ISBN: 0226723356
Format: PDF, ePub
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Nineteenth-century chemists were faced with a particular problem: how to depict the atoms and molecules that are beyond the direct reach of our bodily senses. In visualizing this microworld, these scientists were the first to move beyond high-level philosophical speculations regarding the unseen. In Image and Reality, Alan Rocke focuses on the community of organic chemists in Germany to provide the basis for a fuller understanding of the nature of scientific creativity. Arguing that visual mental images regularly assisted many of these scientists in thinking through old problems and new possibilities, Rocke uses a variety of sources, including private correspondence, diagrams and illustrations, scientific papers, and public statements, to investigate their ability to not only imagine the invisibly tiny atoms and molecules upon which they operated daily, but to build detailed and empirically based pictures of how all of the atoms in complicated molecules were interconnected. These portrayals of “chemical structures,” both as mental images and as paper tools, gradually became an accepted part of science during these years and are now regarded as one of the central defining features of chemistry. In telling this fascinating story in a manner accessible to the lay reader, Rocke also suggests that imagistic thinking is often at the heart of creative thinking in all fields. Image and Reality is the first book in the Synthesis series, a series in the history of chemistry, broadly construed, edited by Angela N. H. Creager, John E. Lesch, Stuart W. Leslie, Lawrence M. Principe, Alan Rocke, E.C. Spary, and Audra J. Wolfe, in partnership with the Chemical Heritage Foundation.

The Science and Business of Drug Discovery

Author: Edward D. Zanders
Publisher: Springer Science & Business Media
ISBN: 9781441999023
Format: PDF, Mobi
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The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge. Its aim is to demystify the jargon used in drug development, but in a way that avoids over simplification and the resulting loss of key information. Each of the nineteen chapters is illustrated with figures and tables which clarify some of the more technical points being made. Also included is a drug discovery case history which draws the relevant material together into a single chapter. In recognizing that it is difficult to navigate through the many external resources dealing with drug development, the book has been written to guide the reader towards the most appropriate information sources, including those listed in the two appendices. The following topics are covered: Different types of drugs: from small molecules to stem cells Background to chemistry of small and large molecules Historical background to drug discovery, pharmacology and biotechnology The drug discovery pipeline: from target discovery to marketed medicine Commercial aspects of drug discovery Challenges to the biopharmaceutical industry and its responses Material of specific interest to technology transfer executives, recruiters and pharmaceutical translators.

Philosophical Chemistry

Author: Manuel DeLanda
Publisher: Bloomsbury Publishing
ISBN: 1472591844
Format: PDF, Mobi
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Philosophical Chemistry furthers Manuel DeLanda's revolutionary intervention in the philosophy of science and science studies. Against a monadic and totalizing understanding of science, DeLanda's historicizing investigation traces the centrality of divergence, specialization and hybridization through the fields and subfields of chemistry. The strategy followed uses a series of chemical textbooks, separated from each other by fifty year periods (1750, 1800, 1850, and 1900), to follow the historical formation of consensus practices. The three chapters deal with one subfield of chemistry in the century in which it was developed: eighteenth-century inorganic chemistry, nineteenth-century organic chemistry, and nineteenth-century physical chemistry. This book creates a model of a scientific field capable of accommodating the variation and differentiation evident in the history of scientific practice. DeLanda proposes a model that is made of three components: a domain of phenomena, a community of practitioners, and a set of instruments and techniques connecting the community to the domain. Philosophical Chemistry will be essential reading for those engaged in emergent, radical and contemporary strands of thought in the philosophy of science and for those scholars and students who strive to practice a productive dialogue between the two disciplines.

The Experimental Self

Author: Jan Golinski
Publisher: University of Chicago Press
ISBN: 022636884X
Format: PDF, Mobi
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What did it mean to be a scientist before the profession itself existed? Jan Golinski finds an answer in the remarkable career of Humphry Davy, the foremost chemist of his day and one of the most distinguished British men of science of the nineteenth century. Originally a country boy from a modest background, Davy was propelled by his scientific accomplishments to a knighthood and the presidency of the Royal Society. An enigmatic figure to his contemporaries, Davy has continued to elude the efforts of biographers to classify him: poet, friend to Coleridge and Wordsworth, author of travel narratives and a book on fishing, chemist and inventor of the miners’ safety lamp. What are we to make of such a man? In The Experimental Self, Golinski argues that Davy’s life is best understood as a prolonged process of self-experimentation. He follows Davy from his youthful enthusiasm for physiological experiment through his self-fashioning as a man of science in a period when the path to a scientific career was not as well-trodden as it is today. What emerges is a portrait of Davy as a creative fashioner of his own identity through a lifelong series of experiments in selfhood.

Arrernte Present Arrernte Past

Author: Diane J. Austin-Broos
Publisher: University of Chicago Press
ISBN: 0226032655
Format: PDF, ePub, Docs
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The Arrernte people of Central Australia first encountered Europeans in the 1860s as groups of explorers, pastoralists, missionaries, and laborers invaded their land. During that time the Arrernte were the subject of intense curiosity, and the earliest accounts of their lives, beliefs, and traditions were a seminal influence on European notions of the primitive. The first study to address the Arrernte’s contemporary situation, Arrernte Present, Arrernte Past also documents the immense sociocultural changes they have experienced over the past hundred years. Employing ethnographic and archival research, Diane Austin-Broos traces the history of the Arrernte as they have transitioned from a society of hunter-gatherers to members of the Hermannsburg Mission community to their present, marginalized position in the modern Australian economy. While she concludes that these wrenching structural shifts led to the violence that now marks Arrernte communities, she also brings to light the powerful acts of imagination that have sustained a continuing sense of Arrernte identity.

Intoxication Modernity and Colonialism

Author: Dušan I. Bjelić
Publisher: Springer
ISBN: 113758856X
Format: PDF, Mobi
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This book depicts how Freud’s cocaine and Benjamin’s hashish illustrate two critiques of modernity and two messianic emancipations through the pleasures of intoxicating discourse. Freud discovered the “libido” and “unconscious” in the industrial mimetic scheme of cocaine, whereas Benjamin found an inspiration for his critique of phantasmagoria and its variant psychoanalysis in hashish’s mimesis. In addition, as part of the history of colonialism, both drugs generated two distinct colonial discourses and, consequently, two different understandings of the emancipatory powers of pleasure, the unconscious, and dreams. After all, great ideas don't liberate; they intoxicate.

Pathways to Modern Chemical Physics

Author: Salvatore Califano
Publisher: Springer Science & Business Media
ISBN: 364228180X
Format: PDF, ePub, Docs
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In this historical volume Salvatore Califano traces the developments of ideas and theories in physical and theoretical chemistry throughout the 20th century. This seldom-told narrative provides details of topics from thermodynamics to atomic structure, radioactivity and quantum chemistry. Califano’s expertise as a physical chemist allows him to judge the historical developments from the point of view of modern chemistry. This detailed and unique historical narrative is fascinating for chemists working in the fields of physical chemistry and is also a useful resource for science historians who will enjoy access to material not previously dealt with in a coherent way.

The Chemical Industry in Europe 1850 1914

Author: Ernst Homburg
Publisher: Springer Science & Business Media
ISBN: 9401732531
Format: PDF, ePub, Mobi
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Europe is the cradle of the modem international chemical industry. From the middle of the nineteenth century until the outbreak of World War I, the European chemical industry influenced not only the production and control of science and technology, but also made significant contributions towards economic development, as well as bringing about profound changes in working and living enviromnents. It is a highly complex heritage, both rich and threatening, that calls for close scrutinity. Fortunately, a unique opportunity to explore the historical development of the European chemical industry from a variety of novel standpoints, was made possible during 1993 as part of the European Science Foundation (ESF) programme called 'The Evolution of Chemistry in Europe, 1789-1939.' This process of exploration has taken place through three workshops, each dealing with different time periods. The workshop concerned with the period 1850-1914, which corresponds roughly to the so-called Second Industrial Revolution, was held in Maastricht, The Netherlands, on 23-25 March 1995. This volume is the outcome of that workshop. The other workshops dealing with European chemical industry were held in Liege in 1994, covering the First Industrial Revolution period, 1789-1850, and Strasbourg in 1996, covering the period between the two World Wars.

The Quiet Revolution

Author: Alan J. Rocke
Publisher: Univ of California Press
ISBN: 9780520081109
Format: PDF, ePub
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"This is one of the most important studies of nineteenth century chemistry produced during the past two decades. Building on his equally important earlier book . . . this work will establish Rocke as the leading scholar in this field."--Frederic L. Holmes, Yale University "With this work, Rocke has become the leading authority on German chemistry in the first two-thirds of the nineteenth century."--Kathryn M. Olesko, Georgetown University