Incretin Biology A Practical Guide

Author: Guy A Rutter
Publisher: World Scientific
ISBN: 1783267380
Format: PDF, ePub
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Together, obesity and diabetes form a 21st century epidemic, the treatment of which consumes a substantial fraction of global health costs. New and improved therapies are therefore desperately needed. Incretins are short peptide hormones released from the gut in response to food transit. These hormones regulate a plethora of processes to control food intake, body weight and glucose homeostasis. This is one of the fastest areas of growth within diabetes research, and over the past decade, increasing numbers of novel diabetes drugs — many based on incretin action — have been added to the therapeutic armoury. Following an introduction detailing the historical perspective and discovery of incretin therapies and clinical applications, the book looks at the release of incretins at a cellular level from entero-endocrine cells, and actions on the pancreas (alpha and beta cells) and brain. It then looks at changes in incretins seen in diabetes and following bariatric surgery. Finally, the side effects of incretin therapy are discussed. Importantly, each chapter contains a methodology section aimed at providing a practical guide to key techniques in the field of incretin biology and ranges from basic laboratory research to clinical practice. Incretin Biology — A Practical Guide offers a unique perspective within this field of research by bringing together scientists, physicians and bariatric surgeons. Thus, it is a comprehensive text that offers a broad overview of the subject. Contents:History of Incretin Discovery and Clinical Application (S E K Zac-Varghese and S R Bloom)Synthesis and Secretion of Incretins from the Gut (A E Adriaenssens, F Reimann and Gribble)Studying Incretin Action on the Pancreatic β Cell (D J Hodson and G A Rutter)Action of Incretins on the Pancreatic α Cell: Control of Glucagon Secretion (L McCulloch, M Godazgar, P Rorsman and R Ramracheya)Role of Incretins in the Brain (J E Richards, S C Cork, M K Holt and S Trapp)Bariatric Surgery: Clinical Aspects (A Ahmed and C Tsironis)GLP-1 in Bariatric Surgery and Diabetes: Underlying Molecular Mechanisms (N B Jørgensen and J J Holst)GLP-1-Based Therapies: What are the Safety Implications? (A Mondragon, A Bertling, R Gomes-Faria, G A Rutter and G da Silva Xavier) Readership: Scientists and clinicians with an emphasis on translational research; biology students; medical students; physicians and bariatric surgeons; and those with an interest in the use of incretins in diabetes and obesity treatment with a view to undertake research within this field. Key Features:Broad overview of the field of incretin biology from a cellular level to clinical applicationDetailed protocols with extensive practical tipsChapters from prominent authors who are currently leading in this fieldKeywords:Incretin;Insulin Secretion;Entero-endocrine Cells;GLP-1;GIP;Dipeptidyl Peptidase-IV Inhibitors;Diabetes;Obesity;Pancreas;Beta Cell;Alpha Cell;Bariatric Surgery;Endocrinology

Practical Guide to Obesity Medicine

Author: Jolanta Weaver
Publisher: Elsevier Health Sciences
ISBN: 0323496008
Format: PDF, ePub, Mobi
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Get a quick, expert overview of the many key facets of obesity management with this concise, practical resource by Dr. Jolanta Weaver. Ideal for any health care professional who cares for patients with a weight problem. This easy-to-read reference addresses a wide range of topics – including advice on how to "unpack" the behavioral causes of obesity in order to facilitate change, manage effective communication with patients suffering with weight problems and future directions in obesity medicine. Features a wealth of information on obesity, including hormones and weight problems, co-morbidities in obesity, genetics and the onset of obesity, behavioral aspects and psychosocial approaches to obesity management, energy and metabolism management, and more. Discusses pharmacotherapies and surgical approaches to obesity. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Management of Diabetes Mellitus

Author: Dr. Diana W. Guthrie, PhD, BC-ADM, CDE, FAADE
Publisher: Springer Publishing Company
ISBN: 9780826119100
Format: PDF
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"I strongly recommend this text. Whether the reader is a relative novice or a seasoned veteran in diabetes care, the information will prove useful and concise and will likely stimulate further reading and study. House staff planning to rotate on my endocrine service should be forewarned: Management of Diabetes Mellitus: A Guide to Pattern Management is now required reading." --JAMA Praise for the previous edition "I recommend this book to nurses or physicians confronting patients afflicted with diabetes mellitus, as it presents a patterned approach to the understanding and management of this malady. Any patient with diabetes mellitus or health care professional using the information presented by these experts would be well prepared to manage this disease process" --Gloria K. Twilley, Lieutenant Colonel United States Air Force Nurse Corps The sixth edition of Management of Diabetes Mellitus fully reorganizes and expands upon the previous editions. While the new edition continues to set forth practical and easy-to-use guidelines for management, the newly expanded chapters contain detailed information on managing patients with different types of diabetes (type 1 and type 2), and further differentiates treatment and management strategies for various age groups. This edition also offers clear and concise explanations of the disease process, newly revised guidelines for the use of complementary and alternative therapies, and a guide for developing an educational program. Guthrie and Guthrie also stress the importance of self-management of diabetes, as much of this edition is dedicated to educating the diabetic patient on how to provide self-care, and control both acute and chronic complications of the disease. For the convenience of practitioners and diabetic patients themselves, this book contains reproducible forms, protocols, and guides that can be used for managing diabetes, including: Nutrition questionnaires Meal patterns comparing exchanges Carb Counting and Calorie Points Sample Calorie Point Distributions Exercise Log Intake Assessment Guide Clinical Practice Recommendations A guide to the "pattern approach"

Chemically Modified Bodies

Author: Matthew Hall
Publisher: Springer
ISBN: 1137535350
Format: PDF, Mobi
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This innovative edited collection brings together leading international academics to explore the use of various non-prescription and prescription substances for the purpose of perceived body image enhancement. While studies on drug misuse to date have examined drug use in the context of sporting performance, addiction, and body image for particular groups such as bodybuilders, there has been little research that explores the wider use (and misuse) of legal and illegal drugs for body image development and weight loss. With medical sociology and social psychology at its core, this important volume shows the complex reasons behind the misuse of various medications, how these are connected to contemporary body image and appearance concerns, and why the known health risks and possibly harmful side effects do not act as deterrents.


Author: Ulrich Mrowietz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805593961
Format: PDF, Mobi
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Mittlerweile in der dritten Auflage informiert dieser schmale Ratgeber umfassend über das Krankheitsbild der Psoriasis, deren Ursachen und Behandlungsmöglichkeiten.

Differenzialdiagnosen in der Computertomografie

Author: Francis A. Burgener
Publisher: Georg Thieme Verlag
ISBN: 3131665327
Format: PDF, Mobi
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- Vom radiologischen Bildbefund ausgehend kann die ganze Palette der Differenzialdiagnosen abgerufen und dann anhand der klinischen Erläuterungen die für den speziellen Fall wahrscheinlichste Diagnose herausgefiltert werden - Besonders hilfreich beim Befunden: Strukturierung nach anatomischen Regionen - Überwältigend: Mit über 2000 CT-Abbildungen zum Nachschlagen - Sie nähern sich der Diagnose durch rasches Screenen der Referenzbilder der betreffenden anatomischen Region - Hunderte differenzialdiagnostischer Tabellen mit detaillierten Erklärungen helfen bei der Differenzierung ähnlicher Befunde - Der Zugriff auf die Diagnosen ist dreifach möglich: von der Lokalisation, vom Erscheinungsbild im CT oder von der Verdachtsdiagnose

Issues in Discovery Experimental and Laboratory Medicine 2011 Edition

Publisher: ScholarlyEditions
ISBN: 1464963509
Format: PDF, ePub, Mobi
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Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Adipositas behandeln mit chinesischer Medizin

Author: Angela Drees
Publisher: Elsevier,Urban&FischerVerlag
ISBN: 9783437570506
Format: PDF
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Das Buch bietet ein Erklärungsmodell für das Problem Adipositas nach den Kriterien der TCM. Es hilft eine differenzierte Diagnose zu stellen und die Patienten mit allen in der TCM verfügbaren Therapieverfahren zu behandeln (Akupunktur, Phytotherapie, Diätetik, Qigong, Tuina). Auch der Einsatz westlicher Kräuter ist in die Behandlungsstrategie integriert. - Mit CD-ROM: Zum Ausdrucken von Informationsmaterial (Rezepte, Qigong-Übungen) für die Patienten.