Introduction to Protein Structure

Author: Carl-Ivar Brändén
Publisher: Taylor & Francis
ISBN: 0815323050
Format: PDF, ePub, Mobi
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This new edition gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context, illustrated in colour to illuminate the structural principles described in the text.

Introduction to Protein Structure

Author: Carl Ivar Branden
Publisher: Garland Science
ISBN: 1136969896
Format: PDF, Mobi
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Introduction to Protein Structure gives an account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full color top illuminate the structural principles described in the text. The first few chapters introduce the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfill a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.

Introduction to Proteins

Author: Amit Kessel
Publisher: CRC Press
ISBN: 1498747183
Format: PDF, Mobi
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Introduction to Proteins shows how proteins can be analyzed in multiple ways. It refers to the roles of proteins and enzymes in diverse contexts and everyday applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. This edition includes a brand-new chapter on enzymatic catalysis and biochemistry, an in-depth discussion of G-protein-coupled receptors (GPCRs), and a wider-scale description of methods for studying proteins.

Introduction to Protein Structure Prediction

Author: Huzefa Rangwala
Publisher: John Wiley & Sons
ISBN: 0470882190
Format: PDF, Kindle
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A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.

Proteins

Author: David Whitford
Publisher: John Wiley & Sons
ISBN: 1118685725
Format: PDF, ePub, Docs
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Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. Opening with a brief historical overview of the subject the book moves on to discuss the ‘building blocks’ of proteins and their respective chemical and physical properties. Later chapters explore experimental and computational methods of comparing proteins, methods of protein purification and protein folding and stability. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of Proteins.

Introduction to Protein Science

Author: Arthur Lesk
Publisher: Oxford University Press
ISBN: 0199541302
Format: PDF, ePub, Docs
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Introduction to Protein Science provides a broad introduction to the contemporary study of proteins in health and disease, suitable for students on biological, biochemical, and biomedical degrees internationally. The book relates the study of proteins to the context of modern high-throughput data streams of genomics and proteomics.

Introduction to Protein Architecture

Author: Arthur M. Lesk
Publisher: Oxford University Press, USA
ISBN: 9780198504740
Format: PDF, ePub, Mobi
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This is truly a monument to the architecture of proteins: a gorgeous tour of the structures that dwell within us. The 'frozen music' of biology is clearly presented in beautiful detail. The computer-generated renderings give pause to anyone who wonders what God was up to when She thought about creating life. Proteins, as represented here, are Her finest efforts. Visually stunning is only the most obvious aspect of this amazing introduction to structural genomics (proteinomics): the systematic study of protein structures. This is a serious graduate level textbook. The text should be considered for any introductory graduate level course in biochemistry. Beginning with sound chemical principles, the text lays a solid foundation for the concepts of secondary and tertiary structure within protein. The author builds a superstructure from which to view the motifs of cofactor binding domains and active sites in enzymes.Based on the authors successful book on the principles of protein structure This book explains the general characteristics of proteins that underlie the very great variety of protein folding patterns observed in nature. It is profusely illustrated with superb computer graphics in full colour throughout the text. Most of the illustrations are stereo diagrams, which are stunning three-dimensional representations of protein structure. The book also introduces the use of the World Wide Web in bioinformatics. To suit the needs of courses, each chapter includes recommended reading, lists of useful web sites, traditional exercises, and a newly-introduced type of exercise called a weblem, for WEB-based probLEM.

Protein Structure and Function

Author: Gregory A. Petsko
Publisher: New Science Press
ISBN: 1405119225
Format: PDF, Kindle
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Each title in the 'Primers in Biology' series is constructed on a modular principle that is intended to make them easy to teach from, to learn from, and to use for reference.

Protein structure

Author: N. J. Darby
Publisher: Oxford University Press, USA
ISBN:
Format: PDF, Mobi
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Proteins play a central role in all biological systems. They fulfill numerous functions which depend upon their complex three-dimensional structures, maintained by a multitude of interactions. This book examines important advances in the understanding of protein structure diversity, the basis of protein stability, and the important relationship between structure and function. These findings have been made possible through the application of key techniques such as X-ray crystallography, NMR, and protein engineering. Protein Structure: In Focus provides comprehensive coverage of this subject for students in biochemistry, biophysics, molecular biology, and related courses, and will also be of great interest to researchers requiring an introduction to this field.