Machine Learning in Medicine a Complete Overview

Author: Ton J. Cleophas
Publisher: Springer
ISBN: 3319151959
Format: PDF, ePub, Mobi
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The current book is the first publication of a complete overview of machine learning methodologies for the medical and health sector. It was written as a training companion and as a must-read, not only for physicians and students, but also for any one involved in the process and progress of health and health care. In eighty chapters eighty different machine learning methodologies are reviewed, in combination with data examples for self-assessment. Each chapter can be studied without the need to consult other chapters. The amount of data stored in the world's databases doubles every 20 months, and clinicians, familiar with traditional statistical methods, are at a loss to analyze them. Traditional methods have, indeed, difficulty to identify outliers in large datasets, and to find patterns in big data and data with multiple exposure / outcome variables. In addition, analysis-rules for surveys and questionnaires, which are currently common methods of data collection, are, essentially, missing. Fortunately, the new discipline, machine learning, is able to cover all of these limitations. So far medical professionals have been rather reluctant to use machine learning. Also, in the field of diagnosis making, few doctors may want a computer checking them, are interested in collaboration with a computer or with computer engineers. Adequate health and health care will, however, soon be impossible without proper data supervision from modern machine learning methodologies like cluster models, neural networks and other data mining methodologies. Each chapter starts with purposes and scientific questions. Then, step-by-step analyses, using data examples, are given. Finally, a paragraph with conclusion, and references to the corresponding sites of three introductory textbooks, previously written by the same authors, is given.

Machine Learning in Medicine

Author: Ton J. Cleophas
Publisher: Springer Science & Business Media
ISBN: 9400778694
Format: PDF
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Machine learning is concerned with the analysis of large data and multiple variables. It is also often more sensitive than traditional statistical methods to analyze small data. The first and second volumes reviewed subjects like optimal scaling, neural networks, factor analysis, partial least squares, discriminant analysis, canonical analysis, fuzzy modeling, various clustering models, support vector machines, Bayesian networks, discrete wavelet analysis, association rule learning, anomaly detection, and correspondence analysis. This third volume addresses more advanced methods and includes subjects like evolutionary programming, stochastic methods, complex sampling, optional binning, Newton's methods, decision trees, and other subjects. Both the theoretical bases and the step by step analyses are described for the benefit of non-mathematical readers. Each chapter can be studied without the need to consult other chapters. Traditional statistical tests are, sometimes, priors to machine learning methods, and they are also, sometimes, used as contrast tests. To those wishing to obtain more knowledge of them, we recommend to additionally study (1) Statistics Applied to Clinical Studies 5th Edition 2012, (2) SPSS for Starters Part One and Two 2012, and (3) Statistical Analysis of Clinical Data on a Pocket Calculator Part One and Two 2012, written by the same authors, and edited by Springer, New York.

Machine Learning and Medical Imaging

Author: Guorong Wu
Publisher: Academic Press
ISBN: 0128041145
Format: PDF, Mobi
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Machine Learning and Medical Imaging presents state-of- the-art machine learning methods in medical image analysis. It first summarizes cutting-edge machine learning algorithms in medical imaging, including not only classical probabilistic modeling and learning methods, but also recent breakthroughs in deep learning, sparse representation/coding, and big data hashing. In the second part leading research groups around the world present a wide spectrum of machine learning methods with application to different medical imaging modalities, clinical domains, and organs. The biomedical imaging modalities include ultrasound, magnetic resonance imaging (MRI), computed tomography (CT), histology, and microscopy images. The targeted organs span the lung, liver, brain, and prostate, while there is also a treatment of examining genetic associations. Machine Learning and Medical Imaging is an ideal reference for medical imaging researchers, industry scientists and engineers, advanced undergraduate and graduate students, and clinicians. Demonstrates the application of cutting-edge machine learning techniques to medical imaging problems Covers an array of medical imaging applications including computer assisted diagnosis, image guided radiation therapy, landmark detection, imaging genomics, and brain connectomics Features self-contained chapters with a thorough literature review Assesses the development of future machine learning techniques and the further application of existing techniques

Machine Learning in Radiation Oncology

Author: Issam El Naqa
Publisher: Springer
ISBN: 3319183052
Format: PDF, ePub
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​This book provides a complete overview of the role of machine learning in radiation oncology and medical physics, covering basic theory, methods, and a variety of applications in medical physics and radiotherapy. An introductory section explains machine learning, reviews supervised and unsupervised learning methods, discusses performance evaluation, and summarizes potential applications in radiation oncology. Detailed individual sections are then devoted to the use of machine learning in quality assurance; computer-aided detection, including treatment planning and contouring; image-guided radiotherapy; respiratory motion management; and treatment response modeling and outcome prediction. The book will be invaluable for students and residents in medical physics and radiation oncology and will also appeal to more experienced practitioners and researchers and members of applied machine learning communities.

Regression Analysis in Medical Research

Author: Ton J. Cleophas
Publisher: Springer
ISBN: 3319719378
Format: PDF, Docs
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This edition is a pretty complete textbook and tutorial for medical and health care students, as well as a recollection/update bench, and help desk for professionals. Novel approaches already applied in published clinical research will be addressed: matrix analyses, alpha spending, gate keeping, kriging, interval censored regressions, causality regressions, canonical regressions, quasi-likelihood regressions, novel non-parametric regressions. Each chapter can be studied as a stand-alone, and covers one field in the fast growing world of regression analyses. The authors, as professors in statistics and machine learning at European universities, are worried, that their students find regression-analyses harder than any other methodology in statistics. This is serious, because almost all of the novel methodologies in current data mining and data analysis include elements of regression-analysis. It is the main incentive for writing this 28 chapter edition, consistent of - 28 major fields of regression analysis, - their condensed maths, - their applications in medical and health research as published so far, - step by step analyses for self-assessment, - conclusion and reference sections. Traditional regression analysis is adequate for epidemiology, but lacks the precision required for clinical investigations. However, in the past two decades modern regression methods have proven to be much more precise. And so it is time, that a book described regression analyses for clinicians. The current edition is the first to do so. It is written for a non-mathematical readership. Self-assessment data-files are provided through Springer' s "Extras Online".

Demystifying Big Data and Machine Learning for Healthcare

Author: Prashant Natarajan
Publisher: CRC Press
ISBN: 1315389304
Format: PDF, ePub, Mobi
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Healthcare transformation requires us to continually look at new and better ways to manage insights – both within and outside the organization today. Increasingly, the ability to glean and operationalize new insights efficiently as a byproduct of an organization’s day-to-day operations is becoming vital to hospitals and health systems ability to survive and prosper. One of the long-standing challenges in healthcare informatics has been the ability to deal with the sheer variety and volume of disparate healthcare data and the increasing need to derive veracity and value out of it. Demystifying Big Data and Machine Learning for Healthcare investigates how healthcare organizations can leverage this tapestry of big data to discover new business value, use cases, and knowledge as well as how big data can be woven into pre-existing business intelligence and analytics efforts. This book focuses on teaching you how to: Develop skills needed to identify and demolish big-data myths Become an expert in separating hype from reality Understand the V’s that matter in healthcare and why Harmonize the 4 C’s across little and big data Choose data fi delity over data quality Learn how to apply the NRF Framework Master applied machine learning for healthcare Conduct a guided tour of learning algorithms Recognize and be prepared for the future of artificial intelligence in healthcare via best practices, feedback loops, and contextually intelligent agents (CIAs) The variety of data in healthcare spans multiple business workflows, formats (structured, un-, and semi-structured), integration at point of care/need, and integration with existing knowledge. In order to deal with these realities, the authors propose new approaches to creating a knowledge-driven learning organization-based on new and existing strategies, methods and technologies. This book will address the long-standing challenges in healthcare informatics and provide pragmatic recommendations on how to deal with them.

Medical Image Recognition Segmentation and Parsing

Author: S. Kevin Zhou
Publisher: Academic Press
ISBN: 0128026766
Format: PDF, Docs
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This book describes the technical problems and solutions for automatically recognizing and parsing a medical image into multiple objects, structures, or anatomies. It gives all the key methods, including state-of- the-art approaches based on machine learning, for recognizing or detecting, parsing or segmenting, a cohort of anatomical structures from a medical image. Written by top experts in Medical Imaging, this book is ideal for university researchers and industry practitioners in medical imaging who want a complete reference on key methods, algorithms and applications in medical image recognition, segmentation and parsing of multiple objects. Learn: Research challenges and problems in medical image recognition, segmentation and parsing of multiple objects Methods and theories for medical image recognition, segmentation and parsing of multiple objects Efficient and effective machine learning solutions based on big datasets Selected applications of medical image parsing using proven algorithms Provides a comprehensive overview of state-of-the-art research on medical image recognition, segmentation, and parsing of multiple objects Presents efficient and effective approaches based on machine learning paradigms to leverage the anatomical context in the medical images, best exemplified by large datasets Includes algorithms for recognizing and parsing of known anatomies for practical applications

Deep Learning for Medical Image Analysis

Author: S. Kevin Zhou
Publisher: Academic Press
ISBN: 0128104090
Format: PDF, Docs
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Deep learning is providing exciting solutions for medical image analysis problems and is seen as a key method for future applications. This book gives a clear understanding of the principles and methods of neural network and deep learning concepts, showing how the algorithms that integrate deep learning as a core component have been applied to medical image detection, segmentation and registration, and computer-aided analysis, using a wide variety of application areas. Deep Learning for Medical Image Analysis is a great learning resource for academic and industry researchers in medical imaging analysis, and for graduate students taking courses on machine learning and deep learning for computer vision and medical image computing and analysis. Covers common research problems in medical image analysis and their challenges Describes deep learning methods and the theories behind approaches for medical image analysis Teaches how algorithms are applied to a broad range of application areas, including Chest X-ray, breast CAD, lung and chest, microscopy and pathology, etc. Includes a Foreword written by Nicholas Ayache

Introduction to Statistical Machine Learning

Author: Masashi Sugiyama
Publisher: Morgan Kaufmann
ISBN: 0128023503
Format: PDF, ePub, Docs
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Machine learning allows computers to learn and discern patterns without actually being programmed. When Statistical techniques and machine learning are combined together they are a powerful tool for analysing various kinds of data in many computer science/engineering areas including, image processing, speech processing, natural language processing, robot control, as well as in fundamental sciences such as biology, medicine, astronomy, physics, and materials. Introduction to Statistical Machine Learning provides a general introduction to machine learning that covers a wide range of topics concisely and will help you bridge the gap between theory and practice. Part I discusses the fundamental concepts of statistics and probability that are used in describing machine learning algorithms. Part II and Part III explain the two major approaches of machine learning techniques; generative methods and discriminative methods. While Part III provides an in-depth look at advanced topics that play essential roles in making machine learning algorithms more useful in practice. The accompanying MATLAB/Octave programs provide you with the necessary practical skills needed to accomplish a wide range of data analysis tasks. Provides the necessary background material to understand machine learning such as statistics, probability, linear algebra, and calculus. Complete coverage of the generative approach to statistical pattern recognition and the discriminative approach to statistical machine learning. Includes MATLAB/Octave programs so that readers can test the algorithms numerically and acquire both mathematical and practical skills in a wide range of data analysis tasks Discusses a wide range of applications in machine learning and statistics and provides examples drawn from image processing, speech processing, natural language processing, robot control, as well as biology, medicine, astronomy, physics, and materials.