Measurement Error in Nonlinear Models

Author: Raymond J. Carroll
Publisher: CRC Press
ISBN: 9781420010138
Format: PDF, Mobi
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It’s been over a decade since the first edition of Measurement Error in Nonlinear Models splashed onto the scene, and research in the field has certainly not cooled in the interim. In fact, quite the opposite has occurred. As a result, Measurement Error in Nonlinear Models: A Modern Perspective, Second Edition has been revamped and extensively updated to offer the most comprehensive and up-to-date survey of measurement error models currently available. What’s new in the Second Edition? · Greatly expanded discussion and applications of Bayesian computation via Markov Chain Monte Carlo techniques · A new chapter on longitudinal data and mixed models · A thoroughly revised chapter on nonparametric regression and density estimation · A totally new chapter on semiparametric regression · Survival analysis expanded into its own separate chapter · Completely rewritten chapter on score functions · Many more examples and illustrative graphs · Unique data sets compiled and made available online In addition, the authors expanded the background material in Appendix A and integrated the technical material from chapter appendices into a new Appendix B for convenient navigation. Regardless of your field, if you’re looking for the most extensive discussion and review of measurement error models, then Measurement Error in Nonlinear Models: A Modern Perspective, Second Edition is your ideal source.

Mixed Effects Models for the Population Approach

Author: Marc Lavielle
Publisher: CRC Press
ISBN: 1482226502
Format: PDF, Mobi
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Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects Models Mixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models. With these models, readers can perform parameter estimation and modeling across a whole population of individuals at the same time. Easy-to-Use Techniques and Tools for Real-World Data Modeling The book first shows how the framework allows model representation for different data types, including continuous, categorical, count, and time-to-event data. This leads to the use of generic methods, such as the stochastic approximation of the EM algorithm (SAEM), for modeling these diverse data types. The book also covers other essential methods, including Markov chain Monte Carlo (MCMC) and importance sampling techniques. The author uses publicly available software tools to illustrate modeling tasks. Methods are implemented in Monolix, and models are visually explored using Mlxplore and simulated using Simulx. Careful Balance of Mathematical Representation and Practical Implementation This book takes readers through the whole modeling process, from defining/creating a parametric model to performing tasks on the model using various mathematical methods. Statisticians and mathematicians will appreciate the rigorous representation of the models and theoretical properties of the methods while modelers will welcome the practical capabilities of the tools. The book is also useful for training and teaching in any field where population modeling occurs.

Measurement Error

Author: John P. Buonaccorsi
Publisher: CRC Press
ISBN: 9781420066586
Format: PDF, Docs
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Over the last 20 years, comprehensive strategies for treating measurement error in complex models and accounting for the use of extra data to estimate measurement error parameters have emerged. Focusing on both established and novel approaches, Measurement Error: Models, Methods, and Applications provides an overview of the main techniques and illustrates their application in various models. It describes the impacts of measurement errors on naive analyses that ignore them and presents ways to correct for them across a variety of statistical models, from simple one-sample problems to regression models to more complex mixed and time series models. The book covers correction methods based on known measurement error parameters, replication, internal or external validation data, and, for some models, instrumental variables. It emphasizes the use of several relatively simple methods, moment corrections, regression calibration, simulation extrapolation (SIMEX), modified estimating equation methods, and likelihood techniques. The author uses SAS-IML and Stata to implement many of the techniques in the examples. Accessible to a broad audience, this book explains how to model measurement error, the effects of ignoring it, and how to correct for it. More applied than most books on measurement error, it describes basic models and methods, their uses in a range of application areas, and the associated terminology.

Analysis of Incomplete Multivariate Data

Author: J.L. Schafer
Publisher: CRC Press
ISBN: 9781439821862
Format: PDF, Kindle
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The last two decades have seen enormous developments in statistical methods for incomplete data. The EM algorithm and its extensions, multiple imputation, and Markov Chain Monte Carlo provide a set of flexible and reliable tools from inference in large classes of missing-data problems. Yet, in practical terms, those developments have had surprisingly little impact on the way most data analysts handle missing values on a routine basis. Analysis of Incomplete Multivariate Data helps bridge the gap between theory and practice, making these missing-data tools accessible to a broad audience. It presents a unified, Bayesian approach to the analysis of incomplete multivariate data, covering datasets in which the variables are continuous, categorical, or both. The focus is applied, where necessary, to help readers thoroughly understand the statistical properties of those methods, and the behavior of the accompanying algorithms. All techniques are illustrated with real data examples, with extended discussion and practical advice. All of the algorithms described in this book have been implemented by the author for general use in the statistical languages S and S Plus. The software is available free of charge on the Internet.

The Bootstrap and Edgeworth Expansion

Author: Peter Hall
Publisher: Springer Science & Business Media
ISBN: 146124384X
Format: PDF, Mobi
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This monograph addresses two quite different topics, each being able to shed light on the other. Firstly, it lays the foundation for a particular view of the bootstrap. Secondly, it gives an account of Edgeworth expansion. The first two chapters deal with the bootstrap and Edgeworth expansion respectively, while chapters 3 and 4 bring these two themes together, using Edgeworth expansion to explore and develop the properties of the bootstrap. The book is aimed at graduate level for those with some exposure to the methods of theoretical statistics. However, technical details are delayed until the last chapter such that mathematically able readers without knowledge of the rigorous theory of probability will have no trouble understanding most of the book.

Nonlinear Models for Repeated Measurement Data

Author: Marie Davidian
Publisher: Routledge
ISBN: 1351428144
Format: PDF, Kindle
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Nonlinear measurement data arise in a wide variety of biological and biomedical applications, such as longitudinal clinical trials, studies of drug kinetics and growth, and the analysis of assay and laboratory data. Nonlinear Models for Repeated Measurement Data provides the first unified development of methods and models for data of this type, with a detailed treatment of inference for the nonlinear mixed effects and its extensions. A particular strength of the book is the inclusion of several detailed case studies from the areas of population pharmacokinetics and pharmacodynamics, immunoassay and bioassay development and the analysis of growth curves.

Semiparametric and Nonparametric Methods in Econometrics

Author: Joel L. Horowitz
Publisher: Springer Science & Business Media
ISBN: 9780387928708
Format: PDF, ePub, Mobi
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Standard methods for estimating empirical models in economics and many other fields rely on strong assumptions about functional forms and the distributions of unobserved random variables. Often, it is assumed that functions of interest are linear or that unobserved random variables are normally distributed. Such assumptions simplify estimation and statistical inference but are rarely justified by economic theory or other a priori considerations. Inference based on convenient but incorrect assumptions about functional forms and distributions can be highly misleading. Nonparametric and semiparametric statistical methods provide a way to reduce the strength of the assumptions required for estimation and inference, thereby reducing the opportunities for obtaining misleading results. These methods are applicable to a wide variety of estimation problems in empirical economics and other fields, and they are being used in applied research with increasing frequency. The literature on nonparametric and semiparametric estimation is large and highly technical. This book presents the main ideas underlying a variety of nonparametric and semiparametric methods. It is accessible to graduate students and applied researchers who are familiar with econometric and statistical theory at the level taught in graduate-level courses in leading universities. The book emphasizes ideas instead of technical details and provides as intuitive an exposition as possible. Empirical examples illustrate the methods that are presented. This book updates and greatly expands the author’s previous book on semiparametric methods in econometrics. Nearly half of the material is new.

Semiparametric Regression

Author: David Ruppert
Publisher: Cambridge University Press
ISBN: 9780521785167
Format: PDF, Kindle
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This user-friendly 2003 book explains the techniques and benefits of semiparametric regression in a concise and modular fashion.

Mixed Effects Models for Complex Data

Author: Lang Wu
Publisher: CRC Press
ISBN: 9781420074086
Format: PDF
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Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to address dropouts, missing data, measurement errors, censoring, and outliers. For each class of mixed effects model, the author reviews the corresponding class of regression model for cross-sectional data. An overview of general models and methods, along with motivating examples After presenting real data examples and outlining general approaches to the analysis of longitudinal/clustered data and incomplete data, the book introduces linear mixed effects (LME) models, generalized linear mixed models (GLMMs), nonlinear mixed effects (NLME) models, and semiparametric and nonparametric mixed effects models. It also includes general approaches for the analysis of complex data with missing values, measurement errors, censoring, and outliers. Self-contained coverage of specific topics Subsequent chapters delve more deeply into missing data problems, covariate measurement errors, and censored responses in mixed effects models. Focusing on incomplete data, the book also covers survival and frailty models, joint models of survival and longitudinal data, robust methods for mixed effects models, marginal generalized estimating equation (GEE) models for longitudinal or clustered data, and Bayesian methods for mixed effects models. Background material In the appendix, the author provides background information, such as likelihood theory, the Gibbs sampler, rejection and importance sampling methods, numerical integration methods, optimization methods, bootstrap, and matrix algebra. Failure to properly address missing data, measurement errors, and other issues in statistical analyses can lead to severely biased or misleading results. This book explores the biases that arise when naïve methods are used and shows which approaches should be used to achieve accurate results in longitudinal data analysis.