Molecular Vaccines

Author: Matthias Giese
Publisher: Springer Science & Business Media
ISBN: 3709114195
Format: PDF, ePub, Docs
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This book gives a comprehensive overview to all aspects of global molecular vaccine research. It introduces concepts of vaccine immunology and molecular vaccine development for viral, bacterial, parasitic and fungal infections. Furthermore, the broad field of research and development in molecular cancer vaccines is discussed in detail. This book is a must have for scientists and clinicians interested in new developments in molecular vaccine research and application in infections and cancer.

Introduction to Molecular Vaccinology

Author: Matthias Giese
Publisher: Springer
ISBN: 331925832X
Format: PDF, ePub, Mobi
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This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

Micro and Nanotechnology in Vaccine Development

Author: Mariusz Skwarczynski
Publisher: William Andrew
ISBN: 0323400299
Format: PDF, Docs
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This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Nanostructures for Oral Medicine

Author: Ecaterina Andronescu
Publisher: Elsevier
ISBN: 0323477216
Format: PDF
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Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

DNA Vaccines

Author: Douglas B. Lowrie
Publisher: Springer Science & Business Media
ISBN: 9780896035805
Format: PDF, Mobi
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This collection of review articles by experts summarize how to develop and employ the highly promising DNA vaccines, what can be expected from their clinical development, and what is know about how they work. The articles include coverage of topics such as immunostimulatory sequences, cytokines, and other adjuvants, as well as practical advice for general and specific applications.

The Microbiology of Respiratory System Infections

Author: Kateryna Kon
Publisher: Academic Press
ISBN: 0128045760
Format: PDF, Docs
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The Microbiology of Respiratory System Infections reviews modern approaches in the diagnosis, treatment, and prophylaxis of respiratory system infections. The book is very useful for researchers, scientists, academics, medical practitioners, graduate and postgraduate students, and specialists from pharmaceutical and laboratory diagnostic companies. The book has been divided into three sections according to the types of respiratory pathogens. The first section contains reviews on the most common and epidemiologically important respiratory viruses, such as influenza virus, severe acute respiratory system coronavirus, and recently discovered Middle East respiratory syndrome coronavirus. The second section is devoted to bacterial and fungal pathogens, which discusses etiology and pathogenesis including infections in patients with compromised immune system, and infections caused by fungal pathogens, such as Aspergillus and Pneumocystis. The third section incorporates treatment approaches against different types of bacterial infections of the lower respiratory tract. This section reviews classical antimicrobial and phytomedical approaches as well as the application of nanotechnology against respiratory pathogens. Offers the most up to date information on the microbiology of lower respiratory system infections Features contributors from across the world, presenting questions of interest to readers of both developed and developing countries Reviews the most common and epidemiologically important respiratory viruses Discusses the etiology and pathogenesis of bacterial and fungal pathogens including infections in patients with compromised immune system, and infections caused by fungal pathogens, such as Aspergillus and Pneumocystis

Immunopotentiators in Modern Vaccines

Author: Virgil Schijns
Publisher: Academic Press
ISBN: 0128040955
Format: PDF, ePub, Docs
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Immunopotentiators in Modern Vaccines, Second Edition, provides in-depth insights and overviews of the most successful adjuvants, those that have been included in licensed products, also covering the most promising technologies that have emerged in recent years. In contrast to existing books on the subject, the chapters here provide summaries of key data on the mechanisms of action of the individual vaccine adjuvants. In addition, the book covers key aspects of how the technologies might be further developed and what might be their limitations, while also giving an overview of what made the most advanced adjuvant technologies successful. Provides contributions from leading international authorities in the field Features immunopotentiators classified by function, with well-illustrated, informative figures presenting the interaction between the immunopotentiators and the host immune system Lists advantages and potential hurdles for achieving a practical application for each specific immunopotentiator Offers US FDA perspectives which highlight how future adjuvants will be approved for new generation vaccines

Transforming Growth Factor Beta in Cancer Therapy Volume II

Author: Sonia B. Jakowlew
Publisher: Springer Science & Business Media
ISBN: 1597452939
Format: PDF
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Transforming Growth Factor- ß in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ß (TGF- ß) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts. The companion volume details the role of TGF- ß on basic and clinical biology.

Vaccine Adjuvants

Author: Derek T. O’Hagan
Publisher: Springer Science & Business Media
ISBN: 9780896037359
Format: PDF
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Annotation Vaccinologists and pharmacologists describe the preparation, characterization, and evaluation of alternative vaccine adjuvants for use in preclinical studies. Each chapter reviews a single, adjuvant and suggests why it might be preferred for a given antigen, depending on what type of immune response is desired. Alternate adjuvant choices are also presented. Methods are described in full detail and range from simple to complex preparation processes. Methods are presented by scientists who originally invented or developed them.