Handbook of Clinical Neuroepidemiology

Author: Valery L. Feigin
Publisher: Nova Publishers
ISBN: 9781600215117
Format: PDF, Docs
Download Now
In recent years there have been significant advances in the knowledge of risk factors, gene-environment interactions, incidence, prevalence, outcomes, and prevention strategies of many neurological disorders. These advances have been accompanied by developments in study design methodologies and statistical analysis. This handbook bridges the gap between current neuroepidemiological knowledge and its evidence-based application in everyday practice.

Neuroepidemiology

Author:
Publisher: Academic Press
ISBN: 0128029900
Format: PDF, Mobi
Download Now
Neuroepidemiology covers the foundations of neuroepidemiological research and the epidemiology of disorders primarily affecting the nervous system, as well as those originating outside the nervous system. The etiology of many important central nervous system disorders remains elusive. Even with diseases where the key risk determinants have been identified, better prevention and therapy is needed to reduce high incidence and mortality. Although evolving technologies for studying disease provide opportunities for such, it is essential for researchers and clinicians to understand how best to apply such technology in the context of carefully characterized patient populations. By paying special attention to methodological approaches, this volume prepares new investigators from a variety of disciplines to conduct epidemiological studies in order to discern the etiologic factors and underlying mechanisms that influence the onset, progression, and recurrence of CNS disorders and diseases. The book also provides current information on methodological approaches for clinical neurologists seeking to expand their knowledge in research. Includes coverage of the foundations of neuroepidemiological research and the epidemiology of disorders primarily affecting the nervous system, as well as those originating outside the nervous system Describes the most recent methodologies to define and quantify the burden of CNS disorders and to understand the underlying mechanisms, with neuroimaging and molecular methods receiving particular emphasis Offers extensive description of those neurological conditions that are secondary to other diseases whose incidence is on the rise because of longer survival rates Features chapters authored by leaders in the field from around the globe

Neuroepidemiology

Author: Lorene M. Nelson
Publisher: Oxford University Press
ISBN: 019513379X
Format: PDF, Docs
Download Now
This fine text provides a comprehensive overview of methods for epidemiologic and clinical research on neurological disorders. The book focuses on classic principles of study design in epidemiologic research, strategies for avoiding study biases, methods for conducting clinical trials and prognostic studies, and principles of evidence-based medicine in neurology. The text gives neurologists, epidemiologists, and their students the foundation for conducting rigorous epidemiologic and clinical research on neurologic disorders.

HIV AIDS and the Nervous System

Author: Peter Portegies
Publisher: Newnes
ISBN: 0444520104
Format: PDF, Mobi
Download Now
This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others. Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies. In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented. * A comprehensive understanding of HIV/AIDS and neuro-AIDS, and the progression of the scientific community's understanding of the disease * Detailed information on fields such as neuroepidemiology, neuropathology, neuropharmacology, and neuroimaging and their contributions to HIV/AIDS research * Subject specific chapters on conditions associated with HIV/AIDS, including opportunistic infections, central nervous system tumors, and myopathies, amongst others

Autoimmune Neurology

Author:
Publisher: Elsevier
ISBN: 0444634460
Format: PDF
Download Now
Autoimmune Neurology presents the latest information on autoimmune neurologic disease, the immune response to the body where organs run wild, causing the immune system to attack itself. Autoimmunity is a main element in numerous nervous system diseases and can target any structure within the central or peripheral nervous system. Over the past 20 years, significant advances in our understanding of the pathophysiology of autoimmune disorders, including the use of biomarkers has led to new diagnosis and treatment options. Neurologic conditions associated with autoimmune reactions include dementia, neuromuscular disease, epilepsy, sleep disorders, diabetes, and other common neurologic disorders and disease. This current tutorial-reference will be a must-have title for clinical neurologists, research neurologists, neuroscientists, and any medical professional working with autoimmune disease and disorders. Includes comprehensive coverage of autoimmune neurology Details the latest techniques for the study, diagnosis, and treatment of diseases and disorders, including dementia, neuromuscular disease, epilepsy, and sleep disorders Presents a focused reference for clinical practitioners and the clinical neurology and neurology research communities

Neurovirology

Author: Alex C. Tselis
Publisher: Newnes
ISBN: 070204539X
Format: PDF, Kindle
Download Now
This volume in the Handbook of Clinical Neurology series provides a complete review of the history, science and current state of neurovirology. It covers the science and clinical presentation, diagnosis, and treatment of viruses of the brain and central nervous system, and is a trusted resource for scholars, scientists, neuroscientists, neurologists, virologists, and pharmacologists working on neurovirology. Neurovirology has been significantly bolstered by modern technologies such as PCR and MRI with direct impact on isolating viruses and advancing therapeutics based on molecular medicine. These advances are particularly important today with the introduction of emerging and re-emerging diseases such as HIV/AIDS, Nipah encephalitis and the appearance of West Nile encephalitis in the western hemisphere. Detailed coverage of neurovirology from the basic science to clinical presentation Covers advances in neurovirology via polymerase chain reaction (PCR) and MRI technology Covers emerging and re-emerging diseases including HIV/AIDS, Nipah encephalitis, and the appearance of West Nile encephalitis in the western hemisphere

Cerebrospinal Fluid in Neurologic Disorders

Author:
Publisher: Elsevier
ISBN: 0128043245
Format: PDF, Mobi
Download Now
Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available

Principles of Neuroepidemiology

Author: Tracy Batchelor
Publisher: Butterworth-Heinemann Medical
ISBN:
Format: PDF, ePub, Docs
Download Now
This unique text offers practitioners both a review of the basic concepts of epidemiology, statistics, and clinical trials and a discussion of the epidemiologic aspects of many neurological diseases. Much of the information contained in Principles of Neuroepidemiology, such as cost-effectiveness analyses, has been difficult for busy practitioners to find in the past. By reading this book, physicians will acquire the skills they need to critically evaluate randomized trials that have affected the clinical practice of neurology.

Multiple Sclerosis and Related Disorders

Author: Douglas S. Goodin
Publisher: Elsevier
ISBN: 044463309X
Format: PDF, ePub
Download Now
Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presence of specific genes seem the most probable targets. MS causes an inflammatory response in the central nervous system leading to neurodegeneration, oligodendrocyte death, axonal damage, and gliosis. Over the past five years ongoing research has greatly expanded our understanding of the pathogenesis of MS, detailed insight into the epidemiology and genetic factors related to MS, the introduction of new technologies and tests to better diagnose and predict the future course of the disease and the introduction of new treatments targeting MS. This collection of review chapters provides a comprehensive reference into the science and clinical applications of the latest Multiple Sclerosis research and will be a valuable resource for the neuroscience research community and the clinical neurology community of researchers and practitioners. A comprehensive tutorial reference detailing our current foundational understanding of Multiple Sclerosis Includes chapters on key topics including the genetics of MS, MRI imaging and MS, and the latest treatment options Each chapter is translational and focuses on current research and impact on diagnosis and treatment options