New Therapeutics for Traumatic Brain Injury

Author: Kim Heidenreich
Publisher: Academic Press
ISBN: 0128027010
Format: PDF, Docs
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New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic

Brain Injury Medicine

Author: Nathan Zasler
Publisher: Demos Medical Publishing
ISBN: 9781888799934
Format: PDF, Docs
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"Brain Injury Medicine: Principles and Practice" is a comprehensive guide to all aspects of the management issues involved in caring for the person with brain injury - from early diagnosis and evaluation through the post-acute period and rehabilitation. It is the definitive core text needed by all practitioners in this area, including ......

Treatment of Cerebral Edema

Author: A. Hartmann
Publisher: Springer
ISBN: 9783540117513
Format: PDF, ePub
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This book contains the papers delivered at the Symposium on "Medical Treatment of Brain Ede ma" at the Seventh International Congress ofNeu rological Surgery, held in Munich in 1981. The aim of each speaker was to give a short review of current knowledge in his or her field. In addition, most of the authors presented their own data. The symposium . was divided into two parts. The experimental part focused on pathophysiological and biochemical findings, while the clinical part dealt with therapy for brain edema, with particular emphasis on steroids. We wish to acknowledge the technical support of Springer-Verlag, Merck Company, Darmstadt and the help of Miss Scholz, Secretary of the Depart ment of Neurology at the University of Heidel berg. Heidelberg/Berlin A. Hartmann M. Brock v Contents K. -A. Hossmann Pathophysiology of Va so genic and Cytotoxic Brain Edema . . . . . . . . . . . . . . . . . . . A. Marrnarou, K. Tanaka, and K. Shulmann The Brain Response to Infusion Edema: Dynamics of Fluid Resolution . . . . . . . . . . 11 M. D. O'Brien 19 Ischemic Cerebral Edema A. Baethmann, W Oettinger, K. Moritake, L. Chaussy, andF. Jesch Metabolic Effects of Corticosteroids in Central Nervous Tissue . . . . . . . . . . . . . 24 K. Maier-Hauff, O. Kempski, A. Unterberg, U. Gross, M. Lange, L. Schurer, and A. Baethmann The Kallikrein-Kinin-System as Mediator in Cerebral Edema, Recent Progress . . . . . . . . . . . . . 31 S. F. Berndt 36 Symptoms of Cerebral Edema W R. Lanksch The Diagnosis of Brain Edema by Computed Tomography . . . . . . . . . . . . . . 43 H. J. Klein and K. Schmidt Hyperosmolar Solutions and Diuretics in the Treatment of Brain Edema . . . . . . . .

Pathobiology of Human Disease

Publisher: Elsevier
ISBN: 0123864577
Format: PDF, Docs
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Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Research and Publishing in Neurosurgery

Author: Yücel Kanpolat
Publisher: Springer Science & Business Media
ISBN: 9783211838211
Format: PDF, Docs
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"Research” and "Publishing” are phrases familiar to all neurosurgeons and neuroscientists. Many young neurosurgeons struggle with them on a trial-and-error basis at first, and there are not structured education programs providing information on standard methods. The European Association of Neurosurgical Societies Research Committee has developed a course on research and publication methods for residents in neurosurgery who have not yet completed training. This supplement includes selected contributions from this course and will serve as an essential handbook providing basic tools to guide research and publication work, presenting time-saving advice, and resulting in the most beneficial contributions in experimental and clinical research.

Mehr als nur ein halbes Leben

Author: Lisa Genova
ISBN: 3838710355
Format: PDF
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Sarah hat alles, wovon sie immer träumte: einen tollen Job, drei wunderbare Kinder, ein schönes Haus und einen liebevollen Mann. Nur eins hat Sarah nicht: Zeit. Bis zu jenem Morgen, an dem ihre Welt zusammenbricht. Auf dem Weg zur Arbeit hat Sarah einen Unfall. Als sie Tage später aus dem Koma erwacht, kann sie ihre linke Körperhälfte nicht mehr steuern. Die einst so selbstständige Frau ist auf einmal von anderen abhängig. Und dazu gezwungen, ihr Leben dramatisch zu entschleunigen. Doch während es Sarah allmählich besser geht, stellt sie sich immer öfter die Frage: Will ich mein altes Leben überhaupt zurück?


Author: M. Stöhr
Publisher: Springer-Verlag
ISBN: 3642587070
Format: PDF, ePub
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Neurophysiologische Untersuchungsverfahren gewinnen im Bereich der Intensivmedizin immer größere praktische Bedeutung. Das Buch stellt die wichtigsten neurophysiologischen Untersuchungsverfahren dar und beschreibt mit praktischen Bewertungskriterien ihre Einsatzmöglichkeiten - auf der Intensiv-Einheit und im OP, - bei häufigen intensivpflichtigen Erkrankungen und diversen chirurgischen Eingriffen an Kopf und Wirbelsäule, - zur intraoperativen Überwachung und Narkosesteuerung. Mit diesem Buch steht endlich eine praxisorientierte Zusammenstellung aller Neuromonitoring-Verfahren zur Verfügung!


Author: Beate Carrière
Publisher: Georg Thieme Verlag
ISBN: 3131703326
Format: PDF, ePub, Docs
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Das Beckenboden-Buch: kompakt, komplett, praxisorientiert - Sicherheit in der Therapie: Internationale Experten erklären, wie man Beckenbodenbeschwerden effektiv mit Physiotherapie behandelt. - Symptome, Untersuchung und Behandlung aller Patientengruppen. - Zahlreiche Behandlungsmethoden: Von Biofeedback über Manualtherapie bis zu Übungsprogrammen und der Triggerpunktbehandlung. - Fundierte Darstellung aktueller Themen, z. B. Rückenschmerzen und Beckenboden oder Beckenbodenstörungen bei onkologischen Erkrankungen. Neu in der 2. Auflage - Alle Kapitel sind aktualisiert und überarbeitet. - Neue Kapitel: Rückenschmerzen und Beckenboden, Lymphdrainage bei Beckenbodenproblemen, Therapie bei Kindern, rektale und anale Dysfunktionen, Beckenboden und Onkologie.