Pediatric Epilepsy

Author: Michael Duchowny
Publisher: McGraw Hill Professional
ISBN: 0071641327
Format: PDF, ePub
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Market: Neurologists and pediatricians Diagnostic and treatment algorithms appear throughout Includes sections on comorbidities and monotherapy vs. polytherapy

Pediatric Epilepsy

Author: Blaise F. Bourgeois, MD
Publisher: Demos Medical Publishing
ISBN: 9781934559864
Format: PDF, Mobi
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The extensively updated third edition of Pediatric Epilepsy: Diagnosis and Therapy continues to be the definitive volume on the diagnosis, treatment, classification, and management of the childhood epilepsies. Written by nearly 100 international leaders in the field, this new edition progresses logically with major sections on the basic mechanisms of the disease, classification, epidemiology, etiology, diagnosis, and age-related syndromes of epilepsy. The core of the new third edition is its completely updated section on antiepileptic drugs, including an in-depth discussion of dosage considerations, drug toxicity, teratogenicity, and drug interactions, with recommendations for optimal combinations when multiple drug therapy is required. Features unique to the third edition include: Expanded section on the basic science and mechanism of epilepsy Completely updated drug chapters, including newly released drugs and those in development Expanded chapters on vagus nerve stimulation and surgical treatment Expanded section on co-morbidities The third edition includes 21 new chapters, including discussions of: epileptic channelopathies; epileptogenic cerebral cortical malformation; epilepsy genes; etiologies and workup; evidence-based medicine issues related to drug selection; Levetiracetam; Sulthiame; Pregabalin; herbal medications; basic and advanced imaging; immunotherapy issues; vagus nerve stimulation therapy; cognitive and psychiatric co-morbidities and educational placement; and psychosocial aspects of epilepsy.

Pediatric Epilepsy Surgery

Author: Oguz Cataltepe
Publisher: Thieme
ISBN: 160406255X
Format: PDF, Mobi
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Written by internationally recognized authorities in pediatric epilepsy surgery, this cutting-edge book provides essential information about the preoperative assessment of and surgical approaches to the treatment of epilepsy in children. The book opens with an overview of pediatric epilepsy followed by four main sections detailing preoperative assessment, surgical approaches and techniques, outcomes, and recent promising advances. The authors present numerous approaches for managing temporal lobe epilepsy and extratemporal lobe epilepsy and guide clinicians through various surgical techniques for hemispherectomy, disconnection procedures, neuromodulation, and more.Highlights: Complete coverage of the selection of surgical candidates, including young patients with congenital or early lesions Detailed discussion of the latest surgical techniques such as hippocampal transection, cortical and deep brain stimulation and radiosurgery Comprehensive presentation of all major hemispherectomy and hemispherotomy techniques More than 100 illustrations, including 85 in full-color, to elucidate key concepts Ideal for pediatric neurosurgeons, epilepsy surgeons and pediatric epileptologists, this authoritative text is also a valuable reference for clinicians, residents, and fellows in neurology, neuroradiology, neuropsychology, and neurophysiology with an interest in pediatric epilepsy surgery.

Pellock s Pediatric Epilepsy

Author: Douglas R. Nordli, Jr., MD
Publisher: Springer Publishing Company
ISBN: 1617052434
Format: PDF
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Now in its fourth edition, Pellock’s Pediatric Epilepsy: Diagnosis and Therapy remains the gold standard for diagnosis, treatment, classification, and management of childhood epilepsies. With over 100 distinguished contributors from world-leading epilepsy programs, the long-awaited new edition maintains the breadth and scope the book is known for while significantly updating the science, practice, and therapeutic strategies that continue to move the field forward. At the center of this new edition is the totally reorganized and expanded section on age-related syndromes. There is a major emphasis on new genetic-based classifications and the clinical implications for identifying and managing the various subtypes. New chapters devoted exclusively to Panayiotopoulos syndrome, myoclonic status epilepticus, and autosomal dominant focal epilepsies, among others, cover even more ground than the last edition. Brand-new chapters in the drug and diet section cover perampanel, ezogabine, and lacosamide, while the existing chapters on major medical treatments have been comprehensively updated to reflect the latest trials and studies. Other sections contain new chapters on genetics, non-invasive functional mapping, sleep issues for pediatric epilepsy patients, and more. With more than 80 chapters, Pellock’s Pediatric Epilepsy now contains a full discussion of the spectrum of epilepsy disorders, not just seizures. From basic mechanisms and epidemiology, through diagnosis and therapy, to quality of life issues, the new edition of this established reference covers every aspect of childhood epilepsy and will continue to be the definitive core text for all professionals involved in the field. New to the Fourth Edition: Every chapter thoroughly reviewed, revised, and updated Section on age-related syndromes completely reconfigured to align with new ILAE terminology and organization in classifying seizures and forms of epilepsy Major update on disease mechanisms and all treatments for epilepsy, including drugs Increased attention to special populations, including a heavily-updated chapter on the female epilepsy patient New final section covers the epilepsy spectrum, with new chapters on epilepsy and sleep, co-morbidities of childhood, behavioral influence of AEDs, and transitioning to adulthood

Pediatric Epilepsy Case Studies

Author: Kevin Chapman
Publisher: CRC Press
ISBN: 142008349X
Format: PDF
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The amount of information currently available on pediatric epilepsy, as with all burgeoning fields, can seem overwhelming. Pediatric Epilepsy Case Studies: From Infancy and Childhood through Adolescence reviews the recent flood of new information on the pathophysiology, genetics, and treatment of the various epilepsy syndromes and distills it into an easy-to-use guide. Edited by respected and well-known leaders in the field, the book provides brief, but thorough, descriptions of the different syndromes commonly encountered in clinical practice across the pediatric range. Grasping the complexity and nuances associated with various epileptic syndromes can be daunting. Therefore, the book begins with an introduction to the fundamentals of epilepsy. Subsequent sections include succinct case presentations and clinically relevant discussions of the more common epilepsy syndromes affecting each age group. The chapter authors describe why they chose each particular case, what they learned, and how it changed their practice. The extensive resource section provides an authoritative guide to relevant findings scattered in the literature. Research in the field of epilepsy will continue at a rapid pace, with the ultimate hope of curing many intractable epilepsy syndromes. Organized chronologically, from neonate through adolescence, this book is the culmination of a group effort involving leading physicians and researchers whose contributions constitute a concise and practical reference for health professionals in training.

Pediatric Brain Stimulation

Author: Adam Kirton
Publisher: Academic Press
ISBN: 0128020385
Format: PDF
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Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brain Edited by renowned leaders in the field of pediatric brain stimulation Presents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry

Epilepsy Across the Spectrum

Author: Committee on the Public Health Dimensions of the Epilepsies
Publisher: National Academies Press
ISBN: 0309255074
Format: PDF, Mobi
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Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Seizures and Epilepsy in Childhood

Author: John M. Freeman
Publisher: Johns Hopkins University Press
ISBN: 9780801870507
Format: PDF, Kindle
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The award-winning Seizures and Epilepsy in Childhood is the standard resource for parents in need of comprehensive medical information about their child with epilepsy. Now in its third edition, this highly praised book has been thoroughly revised and updated to reflect the latest approaches to the diagnosis and treatment of epilepsy in childhood, including the use of the ketogenic diet as a treatment for children who either do not respond to traditional drug therapy or who suffer intolerable side effects from medications. In addition to providing up-to-date information about new diagnostic techniques as well as new drugs, diet, and surgical treatments, the authors have included a chapter addressing routine health care for children with epilepsy and a new chapter on complementary and alternative therapies. Also new to this edition are discussions of the progress made in the evaluation for surgery, a chapter on insurance issues, and a section detailing additional resources. "No child's life should be defined by seizures. If we understand how the brain works, what happens during seizures, and how to cope with epilepsy, we can overcome the mythology of epilepsy and fight society's prejudices, allowing every child with epilepsy to reach his or her full potential."—From Seizures and Epilepsy in Childhood

Inherited Metabolic Epilepsies

Author: Phillip L. Pearl, MD
Publisher: Demos Medical Publishing
ISBN: 1617050563
Format: PDF, ePub, Mobi
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The explosion of information in neurogenetics and metabolism mandates increasing awareness of appropriate diagnostic and therapeutic strategies in the setting of certain epilepsies, especially those of very early onset. There are over 200 inherited disorders that are associated with seizures and prompt identification and intervention is crucial for a positive outcome. This text brings together leading authorities presenting state-of-the-art clinical reviews covering the science, recognition, and treatment of the inherited metabolic epilepsies and related disorders. Inherited Metabolic Epilepsies opens with a section on general principles for diagnosis and targeted intervention including screening protocols, laboratory testing, neuroimaging, seizure patterns and EEG findings, new technologies, and the ketogenic diet in metabolic epilepsies. The next two sections are devoted to the cohort of specific small molecule disorders (aminoacidopathies, organic acidopathies, mitochondrial disorders, urea cycle disorders, neurotransmitter disorders, and glucose-related disorders) and large molecule disorders (lysomal storage disorders, peroxisomal diseases, glycosylation defects, and leukodystrophies) that are treatable yet can be so vexing to clinicians and investigators. The book concludes with a clinical algorithm designed to be a resource for the physician in search of direction when considering an inherited metabolic disorder as the explanation for a patient with epilepsy. Inherited Metabolic Epilepsies Key Features: Presents the latest scientific thinking and clinical wisdom for a poorly understood group of disorders that have devastating consequences if unrecognized or not promptly treated Expert authorship from both the genetic-metabolic and epilepsy communities provides state-of-the-art guidance for understanding and managing these disorders A readable text for clinicians highlighting the relation between metabolic errors and epilepsy Concludes with a practical algorithm for evaluating a patient with a possible metabolic epilepsy