Pharmaceutical Biotechnology

Author: Gary Walsh
Publisher: John Wiley & Sons
ISBN: 111868575X
Format: PDF, ePub, Mobi
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Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals. With a particular focus on the subject taken from a pharmaceutical perspective, initial chapters offer a broad introduction to protein science and recombinant DNA technology- key areas that underpin the whole subject. Subsequent chapters focus upon the development, production and analysis of these substances. Finally the book moves on to explore the science, biotechnology and medical applications of specific biotech products categories. These include not only protein-based substances but also nucleic acid and cell-based products. introduces essential principles underlining modern biotechnology- recombinant DNA technology and protein science an invaluable introduction to this fast-moving subject aimed specifically at pharmacy and medical students includes specific ‘product category chapters’ focusing on the pharmaceutical, medical and therapeutic properties of numerous biopharmaceutical products. entire chapter devoted to the principles of genetic engineering and how these drugs are developed. includes numerous relevant case studies to enhance student understanding no prior knowledge of protein structure is assumed

Pharmaceutical Biotechnology

Author: Daan J. A. Crommelin
Publisher: Springer Science & Business Media
ISBN: 1461464862
Format: PDF, Kindle
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This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry. The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.

Pharmaceutical Biotechnology

Author: Oliver Kayser
Publisher: John Wiley & Sons
ISBN: 3527329943
Format: PDF, ePub
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This second edition of a very successful book is thoroughly updated with existing chapters completely rewritten while the content has more than doubled from 16 to 36 chapters. As with the first edition, the focus is on industrial pharmaceutical research, written by a team of industry experts from around the world, while quality and safety management, drug approval and regulation, patenting issues, and biotechnology fundamentals are also covered. In addition, this new edition now not only includes biotech drug development but also the use of biopharmaceuticals in diagnostics and vaccinations. With a foreword by Robert Langer, Kenneth J Germeshausen Professor of Chemical and Biomedical Engineering at MIT and member of the National Academy of Engineering and the National Academy of Sciences.

Pharmaceutical Biotechnology

Author: K. Sambamurthy
Publisher: New Age International
ISBN: 9788122417838
Format: PDF
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The Textbook On Pharmaceutical Biotechnology Provides Comprehensively The Fundamental Concepts And Principles In Biotechnology To Expatiate And Substantiate Its Numerous Modern Applications With Regard To The Spectacular Development In The Pharmaceutical Industry. In A Broader Perspective, The Students Studying Biotechnology At Undergraduate And Postgraduate Levels Shall Be Grossly Benefited By Its Well-Planned Systematically Developed, Structured, Illustrated, Expanded, Elaborated, And Profusely Exemplified Subject Matter.It Essentially Comprise Five Major Chapters, Namely: Immunology And Immunological Preparations; Genetic Recombination; Antibiotics; Microbial Transformations; And Enzyme Immobilization. Besides, There Are Five Auxiliary Chapters, Namely, Advent Of Biotechnology; Biosensor Technology; Bioinformatics And Data Mining; Regulatory Issues In Biotechnology; And Safety In Biotechnology, Which Have Been Specifically Included So As To Stimulate The Students, Interest And Broaden Their Horizon Of Knowledge And Wisdom.The Authors Earnestly Believe That The Wide Coverage Of Various Topics Mentioned Above Would Certainly Render Pharmaceutical Biotechnology To Serve As An Exclusive Source Of Information S, Ideas, Inspirations Towards Research, And Finding Newer Possible Practical Solutions To Problems Encountered In The Ever Green Pasture Using Knowledge Of Biotechnology In The Pharmaceutical Industry.

Handbook of Pharmaceutical Biotechnology

Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 9780470117101
Format: PDF
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A practical overview of a full rangeof approaches to discovering, selecting, and producing biotechnology-derived drugs The Handbook of Pharmaceutical Biotechnology helps pharmaceutical scientists develop biotech drugs through a comprehensive framework that spans the process from discovery, development, and manufacturing through validation and registration. With chapters written by leading practitioners in their specialty areas, this reference: Provides an overview of biotechnology used in the drug development process Covers extensive applications, plus regulations and validation methods Features fifty chapters covering all the major approaches to the challenge of identifying, producing, and formulating new biologically derived therapeutics With its unparalleled breadth of topics and approaches, this handbook is a core reference for pharmaceutical scientists, including development researchers, toxicologists, biochemists, molecular biologists, cell biologists, immunologists, and formulation chemists. It is also a great resource for quality assurance/assessment/control managers, biotechnology technicians, and others in the biotech industry.

Industrial pharmaceutical biotechnology

Author: Heinrich Klefenz
Publisher: Vch Verlagsgesellschaft Mbh
ISBN: 9783527299959
Format: PDF
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This volume focuses on pharmaceutical biotechnology as a key area of life sciences. The complete range of concepts, processes and technologies of biotechnology is applied in modern industrial pharmaceutical research, development and production. The results of genome sequencing and studies of biological-genetic function are combined with chemical, micro-electronic and microsystem technology to produce medical devices and diagnostic biochips. A multitude of biologically active molecules is expanded by additional novel structures created with newly arranged gene clusters and bio-catalytic chemical processes. New organisational structures in the co-operation of institutes, companies and networks enable faster knowledge and product development and immediate application of the results of research and process development. This book is the ideal source of information for scientists and engineers in research and development, for decision-makers in biotech, pharma and chemical corporations, as well as for research institutes, but also for founders of biotech companies and people working for venture capital corporations.

Pharmaceutical Biotechnology

Author: Carlos A. Guzmán
Publisher: Springer Science & Business Media
ISBN: 9781441911322
Format: PDF, Mobi
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Pharmaceutical Biotechnology is a unique compilation of reviews addressing frontiers in biologicals as a rich source for innovative medicines. This book fulfills the needs of a broad community of scientists interested in biologicals from diverse perspectives—basic research, biotechnology, protein engineering, protein delivery, medicines, pharmaceuticals and vaccinology. The diverse topics range from advanced biotechnologies aimed to introduce novel, potent engineered vaccines of unprecedented efficacy and safety for a wide scope of human diseases to natural products, small peptides and polypeptides engineered for discrete prophylaxis and therapeutic purposes. Modern biologicals promise to dramatically expand the scope of preventive medicine beyond the infectious disease arena into broad applications in immune and cancer treatment, as exemplified by anti-EGFR receptors antibodies for the treatment of breast cancer. The exponential growth in biologicals such as engineered proteins and vaccines has been boosted by unprecedented scientific breakthroughs made in the past decades culminating in an in-depth fundamental understanding of the scientific underpinnings of immune mechanisms together with knowledge of protein and peptide scaffolds that can be deliberately manipulated. This has in turn led to new strategies and processes. Deciphering the human, mammalian and numerous pathogens’ genomes provides opportunities that never before have been available—identification of discrete antigens (genomes and antigenomes) that lend themselves to considerably improved antigens and monoclonal antibodies, which with more sophisticated engineered adjuvants and agonists of pattern recognition receptors present in immune cells, deliver unprecedented safety and efficacy. Technological development such a nanobiotechnologies (dendrimers, nanobodies and fullerenes), biological particles (viral-like particles and bacterial ghosts) and innovative vectors (replication-competent attenuated, replication-incompetent recombinant and defective helper-dependent vectors) fulfill a broad range of cutting-edge research, drug discovery and delivery applications. Most recent examples of breakthrough biologicals include the human papilloma virus vaccine (HPV, prevention of women genital cancer) and the multivalent Pneumoccocal vaccines, which has virtually eradicated in some populations a most prevalent bacterial ear infection (i.e., otitis media). It is expected that in the years to come similar success will be obtained in the development of vaccines for diseases which still represent major threats for human health, such as AIDS, as well as for the generation of improved vaccines against diseases like pandemic flu for which vaccines are currently available. Furthermore, advances in comparative immunology and innate immunity revealed opportunities for innovative strategies for ever smaller biologicals and vaccines derived from species such as llama and sharks, which carry tremendous potential for innovative biologicals already in development stages in many pharmaceutical companies. Such recent discoveries and knowledge exploitations hold the promise for breakthrough biologicals, with the coming decade. Finally, this book caters to individuals not directly engaged in the pharmaceutical drug discovery process via a chapter outlining discovery, preclinical development, clinical development and translational medicine issues that are critical the drug development process. The authors and editors hope that this compilation of reviews will help readers rapidly and completely update knowledge and understanding of the frontiers in pharmaceutical biotechnologies.

Pharmaceutical biotechnology

Author: S. William Zito
Publisher: CRC
ISBN:
Format: PDF, ePub, Docs
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The explosion of knowledge in the area of pharmaceutical biotechnology can certainly justify the need for a second edition of this text. While new techniques and topics have been introduced to ensure the content is current, the format of Pharmaceutical Biotechnology, 2nd Edition has remained essentially unchanged. It provides a clear, concise self-teaching guide to the essentials of pharmaceutical biotechnology. Key topics are covered systematically, with self-tests at the end of each chapter, helping the reader acquire a basic fund of knowledge in this important area of pharmacology.While prepared for undergraduate pharmacy students, this self-teaching text also serves the professional needs of all those in drug research, development, administration and government regulation.