Pioneers of Medicine Without a Nobel Prize

Author: Gilbert Thompson
Publisher: World Scientific
ISBN: 1783263865
Format: PDF, Docs
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This book brings together in one volume fifteen discoveries that have had a major impact upon medical science and the practice of medicine but where the scientists involved have not been awarded a Nobel Prize. Its aim is to publicize the achievements of these lesser-known heroes of our time and thereby inform and entertain the reader, whether medical student, professor or scientifically-minded layman. Contents:Archibald E Garrod: The Founding Father of Biochemical Genetics (David J Galton)Nikolai Anitschkow: The Birth of the Lipid Hypothesis of Atherosclerosis and Coronary Heart Disease (Daniel Steinberg)Willem-Karel Dicke: The Role of Gluten in Coeliac Disease (Chris J J Mulder and Karel A Dicke)Richard Doll: The Link Between Smoking and Lung Cancer (Tony Seed)Albert Sabin: The Development of an Oral Poliovirus Vaccine (Derek R Smith and Peter A Leggat)René Favaloro: Pioneer of Coronary Artery Surgery (Stephen Westaby)Christiaan Barnard and Norman Shumway: The Heart Transplant Pioneers (Stephen Westaby and David Marais)William Kouwenhoven and Paul Zoll: The Introduction of External Cardiac Massage, Defibrillators and Pacemakers (Max Lab)Inge Edler and Carl Hellmuth Hertz: The Development of Ultrasound for Clinical Use (Bhavna Batohi and Paul S Sidhu)Cyril Clarke, Ronald Finn, John Gorman, Vincent Freda and William Pollack: The Prevention of Rh Haemolytic Disease of the Newborn (David J Weatherall)Herbert Boyer and Stanley Cohen: Recombinant DNA (Anne Soutar)Harvey Alter and Michael Houghton: The Discovery of Hepatitis C and the Introduction of Screening to Prevent Its Transmission in Transfused Blood (Leonard B Seeff and Marc G Ghany)Willem Kolff and Belding Scribner: The Development of Renal Haemodialysis (John Turney)James Till and Ernest Mcculloch: The Discovery of Stem Cells (Joe Sornberger)Akira Endo: The Discovery of Statins (Gilbert Thompson and Hiroshi Mabuchi) Readership: Medical students, professionals and general public. Key Features:This book is the sequel to Nobel Prizes that Changed Medicine. Many of the authors have personal knowledge of the scientists they write about and all are distinguished authorities in their own field. No other book has brought together the non-Nobel Prize-winning discoveries having the greatest influence upon the practice of Medicine, dating from the first description of inborn errors of metabolism by Garrod in 1908 to the discovery of statins, for which Endo received the Lasker Award in 2008Keywords:Inborn Errors;Metabolism;Lipid Hypothesis;Atherosclerosis;Gluten;Coeliac Disease;Smoking;Lung Cancer;Polio Vaccine;Coronary Angiography;Coronary Bypass Grafting;Cardiac Transplantation;Cardiac Massage;Defibrillator;Pace Maker;Ultrasound;Rh Disease;Gene Cloning;Hepatitis C;Haemodialysis;Stem-Cells;Statins

Pioneers of Medicine Without a Nobel Prize

Author: Gilbert R. Thompson
Publisher:
ISBN: 9781783263837
Format: PDF, ePub, Docs
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This book brings together in one volume 15 discoveries that have had a great impact upon medical science and the practice of medicine during the 20th and early 21st centuries but where the scientists involved have not yet been awarded a Nobel Prize. Its overall aim is to publicize the achievements of these lesser-known heroes of our time and thereby entertain the reader, whether medical student or professor.

Pioneers of Microbiology and the Nobel Prize

Author: Ulf Lagerkvist
Publisher: World Scientific
ISBN: 9814338087
Format: PDF
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We are swamped with information and each day seems to bring new discoveries that must be considered. Never before in the history of science have so many scientists been as active as today. It has become a major problem for the expert just to keep up with the literature in his or her own field of research. Why, then, should experts and their poor students worry about the pioneers of microbiology, those half-forgotten scientists who a century ago devoted their lives to a new science that was on its way to revolutionizing medicine? With so many new facts and problems screaming for our attention, it is easy to lose sight of the long road that we have travelled in order to get to the point where we are now. Tracing the path of those who have gone before us will help us to see our own scientific goals and efforts in a more revealing perspective. The great figures who are at the center of interest in this book — Robert Koch, Emil von Behring, Paul Ehrlich and Elie Metchnikoff — were far from uncontroversial during their lifetimes. It is interesting to see how they were judged by their peers at the Karolinska Institutet when they were considered for the Nobel Prize. Pioneers of Microbiology and the Nobel Prize has been written in such a way that it can be enjoyed even without an extensive knowledge of microbiology and medicine. In fact, a considerable part of the book portrays the state of medicine during the middle of the 19th century, when bacteriology can be said to have made its debut on the medical scene. Contents:The Sites of DiseasesCellular PathologyThe New PhysiologyBankruptcy and a Gleam of HopeContagion Versus MiasmaThe Birth of MicrobiologyBacteriology and the Nemesis of SurgeryRobert KochEmil von BehringPaul EhrlichElie MetchnikoffNobel Prizes and Nobel Committees (1901, 1905 and 1908)In Defence of the Nobel Prize Readership: Microbiologists; medical researchers, undergraduates and graduate students in microbiology and the life sciences; general readers. Keywords:Microbiology;Medical History;Nobel Prize;Robert Koch;Emil von Behring;Paul Ehrlich;Elie MetchnikoffReviews:“… The four main sections of the book are each a gem of a portrait in the miniature. The treatment is balanced; not only human greatness but failings are presented, making the descriptions very human and informative … Ulf Lagerkvist provides interesting data and observations about the nominations and the studies conducted by various members of the Committee on the candidates.”István Hargittai Budapest University of Technology and Economics, Hungary “Lagerkvist has written an extremely informative and simple description of four giants in the field of microbiology. His easy-going style and a focus on the straightforward elements of the lives of the Nobelists make for a voyage of entertainment and education.”Sidney Altman Yale University, USA “It is an informative review of the notable achievements of four great figures in medicine whose researches have virtually been eclipsed by the rapid advances of the 20th century.”Paul Berg Stanford University Medical Center, USA “This timely book reminds us of the achievements and careers of the equally great scientific pioneers of a hundred years ago, who discovered most of the agents that cause major human diseases, and also revealed our main defence against infectious agents, the antibodies … The author provides fascinating insights into the deliberations which resulted in well deserved awards for several scientific pioneers. This is an insiders' view of the strategy for choosing the right candidates for Nobel prizes.”Tomas Lindahl Cancer Research UK London Research Institute “Just over 100 years ago, the first Nobel Prize in Physiology or Medicine was awarded. This book is an authoritative and entertaining account of four of the early winners. The life and work of Robert Koch, Emil von Behring, Paul Ehrlich and Elie Metchnikoff are closely examined in the light of contemporary scientific knowledge and ignorance. Politics appear to have had as much to do with their final acceptance as Nobel Prize winners as did their outstanding scientific achievements. Many full-page portraits add to the charm of this book. Members of the public wanting to learn more about the birth of microbiology will find this book invaluable. Trainee as well as experienced microbiologists and immunologists will also find much of interest. There should be a copy in the often neglected history section of all good microbiologists libraries.”Microbiology Today “The book supplies superior details about the research and the social climate leading to the discoveries and provides good insight into the intellect and personalities that make extraordinary scientific discoveries. The rationale for awarding Nobel prizes in science is also thoroughly discussed … For anybody interested in the history and process of science.”Choice “The initial chapters beautifully describe the evolution of the ideas that formed the basis not only of medical microbiology but also of physiology and pathology … This book provides a series of portraits in which not only the achievements but additionally the failings are described, and effectively conjures up the academic milieu of the time.”Notes and Records of The Royal Society

Nobel Prizes that Changed Medicine

Author: Gilbert Thompson
Publisher: World Scientific
ISBN: 1848168276
Format: PDF, ePub, Docs
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This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain detailed information on the topic by accessing the Nobel Foundation''s website. In contrast, this book aims to provide a less formal and more personal view of the science and scientists involved, by having prominent academics write a chapter each about a Nobel Prize-winning discovery in their own areas of interest and expertise.

Cancer Immune Therapy

Author: Gernot Stuhler
Publisher: John Wiley & Sons
ISBN: 9783527304417
Format: PDF, Mobi
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Cure or life with cancer? What can be achieved by cancer immune therapy? The past decade has seen substantial advancements in tumor immunology. Much of the new knowledge has been translated into new strategies for cancer treatment and into clinical trials. Some of these trials herald future breakthroughs, others have been disappointing and have prompted intensive search for alternatives.Major contributors to the field summarize the knowledge on the molecular and cellular mechanisms of tumorigenesis, critically review the instruments of the immune system that might be exploited for therapy, and discuss the clinical experiences with the different immune therapy concepts. Researchers in the fields of immunology, tumor biology and medicine will highly appreciate this up-to-date volume for evaluating future research activities.

Minds behind the Brain A History of the Pioneers and Their Discoveries

Author: Department of Psychology Washington University Stanley Finger Professor
Publisher: Oxford University Press, USA
ISBN: 0198024681
Format: PDF, ePub, Docs
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Attractively illustrated with over a hundred halftones and drawings, this volume presents a series of vibrant profiles that trace the evolution of our knowledge about the brain. Beginning almost 5000 years ago, with the ancient Egyptian study of "the marrow of the skull," Stanley Finger takes us on a fascinating journey from the classical world of Hippocrates, to the time of Descartes and the era of Broca and Ramon y Cajal, to modern researchers such as Sperry. Here is a truly remarkable cast of characters. We meet Galen, a man of titanic ego and abrasive disposition, whose teachings dominated medicine for a thousand years; Vesalius, a contemporary of Copernicus, who pushed our understanding of human anatomy to new heights; Otto Loewi, pioneer in neurotransmitters, who gave the Nazis his Nobel prize money and fled Austria for England; and Rita Levi-Montalcini, discoverer of nerve growth factor, who in war-torn Italy was forced to do her research in her bedroom. For each individual, Finger examines the philosophy, the tools, the books, and the ideas that brought new insights. Finger also looks at broader topics--how dependent are researchers on the work of others? What makes the time ripe for discovery? And what role does chance or serendipity play? And he includes many fascinating background figures as well, from Leonardo da Vinci and Emanuel Swedenborg to Karl August Weinhold--who claimed to have reanimated a dead cat by filling its skull with silver and zinc--and Mary Shelley, whose Frankenstein was inspired by such experiments. Wide ranging in scope, imbued with an infectious spirit of adventure, here are vivid portraits of giants in the field of neuroscience--remarkable individuals who found new ways to think about the machinery of the mind.

Women Pioneers of Medical Research

Author: King-Thom Chung
Publisher: McFarland
ISBN: 9780786458172
Format: PDF, ePub, Docs
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While most laymen could recognize Florence Nightingale as the founder of modern nursing, it's doubtful they could likewise identify Louise Pearce as one of the primary researchers in the cure for African Sleeping Sickness or Anna W. Williams as the discoverer of the diphtheria antitoxin. This book profiles 25 women who have made significant contributions to medical research, including Lady Mary Wortley Montagu, Lydia Folger Fowler, Virginia Apgar, and Rosalind Franklin, among others. Each profile includes a general introduction and covers the woman's childhood or family background, her formal education, her most valuable contributions to the field, and the important events or persons which influenced her life and career.

Curious Naturalists

Author: Dr. Niko Tinbergen
Publisher: Pickle Partners Publishing
ISBN: 1787209016
Format: PDF, Kindle
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Dr. Niko Tinbergen was well known as a naturalist and a student of animal behaviour in England, on the Continent and in the United States. Ever since he was a young student in Holland he had been curious about nature, and in this book he sets out some of the facts that 25 years of curiosity gave him. As a biologist, anything living was his province—the bee-killing wasps and the digger wasps of the Dutch sand dunes; the Snow Bruntings and Phalaropes of Greenland; Hobbies and other hawks; moths and butterflies in various parts of England and Holland; Black-headed Gulls of the Ravenglass nature reserve, Cumberland, the Kittiwakes and Eider Ducks of the Farne Islands off the coast of Northumberland. Readers cannot fail to be struck—and possibly sometimes amused—by the patience and ingenuity shown in the field studies undertaken by Dr. Tinbergen and his fellow naturalists—and which are now passed on for the benefit and interest of his readers. The studies were always undertaken seriously, but this did not prevent Dr. Tinbergen from writing about them in the liveliest way; he realised that quite often he and his friends must have seemed to onlookers to be very curious naturalists indeed.

Nobel Prizes and Life Sciences

Author: Erling Norrby
Publisher: World Scientific
ISBN: 9814299367
Format: PDF
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The Nobel Prizes m natural sciences have achieved the reputation of being the ultimate accolade for scientific achievements. This honk gives a unique insight into the selection of Nobel Prize recipients, in particular the life sciences. The evolving mechanisms of selection of prize recipients are illustrated by reference to archives, which have remained secret for 1) years. Many of the prizes subjected to particular evaluation concern awards given for discoveries in the field of infectious diseases and the interconnected field of genetics. The book illustrates the individuals and environments that are conducive to scientific creativity. Nowhere is this enigmatic activity'-- the mime mover in advancing the human condition highlighted as lucidly as by identification individuals worthy of Nobel Prizes. --Book Jacket.

Journey Into the Heart

Author: David Monagan
Publisher: Penguin
ISBN: 9781592402656
Format: PDF
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The twentieth-century journey to understand the human heart was a saga on a par with the race to the moon. Physicians have evolved from fearing to even touch a living human heart to rebuilding and transplanting hearts. Today heart attacks can often be sto