Proton Therapy Physics

Author: Harald Paganetti
Publisher: CRC Press
ISBN: 1439836450
Format: PDF, ePub
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Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Proton Therapy Physics Second Edition

Author: Harald Paganetti
Publisher: CRC Press
ISBN: 9781138626508
Format: PDF, Mobi
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Expanding on the highly successful first edition,this second edition of Proton Therapy Physicshas been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature. After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed. This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics.

Proton Therapy Physics

Author: Harald Paganetti
Publisher: CRC Press
ISBN: 9781439836446
Format: PDF, Kindle
Download Now
Proton Therapy Physics goes beyond current books on proton therapy to provide an in-depth overview of the physics aspects of this radiation therapy modality, eliminating the need to dig through information scattered in the medical physics literature. After tracing the history of proton therapy, the book summarizes the atomic and nuclear physics background necessary for understanding proton interactions with tissue. It describes the physics of proton accelerators, the parameters of clinical proton beams, and the mechanisms to generate a conformal dose distribution in a patient. The text then covers detector systems and measuring techniques for reference dosimetry, outlines basic quality assurance and commissioning guidelines, and gives examples of Monte Carlo simulations in proton therapy. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. It also examines computerized treatment plan optimization, methods for in vivo dose or beam range verification, the safety of patients and operating personnel, and the biological implications of using protons from a physics perspective. The final chapter illustrates the use of risk models for common tissue complications in treatment optimization. Along with exploring quality assurance issues and biological considerations, this practical guide collects the latest clinical studies on the use of protons in treatment planning and radiation monitoring. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, the book helps readers understand the uncertainties and limitations of precisely shaped dose distribution.

Graphics Processing Unit Based High Performance Computing in Radiation Therapy

Author: Xun Jia
Publisher: CRC Press
ISBN: 1482244799
Format: PDF, ePub, Docs
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Use the GPU Successfully in Your Radiotherapy Practice With its high processing power, cost-effectiveness, and easy deployment, access, and maintenance, the graphics processing unit (GPU) has increasingly been used to tackle problems in the medical physics field, ranging from computed tomography reconstruction to Monte Carlo radiation transport simulation. Graphics Processing Unit-Based High Performance Computing in Radiation Therapy collects state-of-the-art research on GPU computing and its applications to medical physics problems in radiation therapy. Tackle Problems in Medical Imaging and Radiotherapy The book first offers an introduction to the GPU technology and its current applications in radiotherapy. Most of the remaining chapters discuss a specific application of a GPU in a key radiotherapy problem. These chapters summarize advances and present technical details and insightful discussions on the use of GPU in addressing the problems. The book also examines two real systems developed with GPU as a core component to accomplish important clinical tasks in modern radiotherapy. Translate Research Developments to Clinical Practice Written by a team of international experts in radiation oncology, biomedical imaging, computing, and physics, this book gets clinical and research physicists, graduate students, and other scientists up to date on the latest in GPU computing for radiotherapy. It encourages you to bring this novel technology to routine clinical radiotherapy practice.

Ion Beam Therapy

Author: Ute Linz
Publisher: Springer Science & Business Media
ISBN: 3642214142
Format: PDF, ePub, Mobi
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The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.

The Physics of Three Dimensional Radiation Therapy

Author: S. Webb
Publisher: CRC Press
ISBN: 9781420050363
Format: PDF, Kindle
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The Physics of Three Dimensional Radiation Therapy presents a broad study of the use of three-dimensional techniques in radiation therapy. These techniques are used to specify the target volume precisely and deliver radiation with precision to minimize damage to surrounding healthy tissue. The book discusses multimodality computed tomography, complex treatment planning software, advanced collimation techniques, proton radiotherapy, megavoltage imaging, and stereotactic radiosurgery. A review of the literature, numerous questions, and many illustrations make this book suitable for teaching a course. The themes covered in this book are developed and expanded in Webb's The Physics of Conformal Radiotherapy and the two may be used together or in successive semesters for teaching purposes.

Proton and Carbon Ion Therapy

Author: C-M Charlie Ma
Publisher: CRC Press
ISBN: 1439816077
Format: PDF, Mobi
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Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.

Medical Physics and Biomedical Engineering

Author: B.H Brown
Publisher: CRC Press
ISBN: 9780750303682
Format: PDF, Mobi
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Medical Physics and Biomedical Engineering provides broad coverage appropriate for senior undergraduates and graduates in medical physics and biomedical engineering. Divided into two parts, the first part presents the underlying physics, electronics, anatomy, and physiology and the second part addresses practical applications. The structured approach means that later chapters build and broaden the material introduced in the opening chapters; for example, students can read chapters covering the introductory science of an area and then study the practical application of the topic. Coverage includes biomechanics; ionizing and nonionizing radiation and measurements; image formation techniques, processing, and analysis; safety issues; biomedical devices; mathematical and statistical techniques; physiological signals and responses; and respiratory and cardiovascular function and measurement. Where necessary, the authors provide references to the mathematical background and keep detailed derivations to a minimum. They give comprehensive references to junior undergraduate texts in physics, electronics, and life sciences in the bibliographies at the end of each chapter.

Radiation Oncology A Physicist s Eye View

Author: Michael Goitein
Publisher: Springer Science & Business Media
ISBN: 0387726454
Format: PDF, ePub, Mobi
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The papers collected in this hugely useful volume cover the principle physical and biological aspects of radiation therapy and in addition, address practical clinical considerations in the planning and delivering of that therapy. The importance of the assessment of uncertainties is emphasized. Topics include an overview of the physics of the interactions of radiation with matter and the definition of the goals and the design of radiation therapy approaches.

Handbook of Anatomical Models for Radiation Dosimetry

Author: Xie George Xu
Publisher: CRC Press
ISBN: 9781420059809
Format: PDF, ePub, Docs
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Over the past few decades, the radiological science community has developed and applied numerous models of the human body for radiation protection, diagnostic imaging, and nuclear medicine therapy. The Handbook of Anatomical Models for Radiation Dosimetry provides a comprehensive review of the development and application of these computational models, known as "phantoms." An ambitious and unparalleled project, this pioneering work is the result of several years of planning and preparation involving 64 authors from across the world. It brings together recommendations and information sanctioned by the International Commission on Radiological Protection (ICRP) and documents 40 years of history and the progress of those involved with cutting-edge work with Monte Carlo Codes and radiation protection dosimetry. This volume was in part spurred on by the ICRP’s key decision to adopt voxelized computational phantoms as standards for radiation protection purposes. It is an invaluable reference for those working in that area as well as those employing or developing anatomical models for a a number of clinical applications. Assembling the work of nearly all major phantom developers around the world, this volume examines: The history of the research and development in computational phantoms Detailed accounts for each of the well-known phantoms, including the MIRD-5, GSF Voxel Family Phantoms, NCAT, UF Hybrid Pediatric Phantoms, VIP-Man, and the latest ICRP Reference Phantoms Physical phantoms for experimental radiation dosimetry The smallest voxel size (0.2 mm), phantoms developed from the Chinese Visible Human Project Applications for radiation protection dosimetry involving environmental, nuclear power plant, and internal contamination exposures Medical applications, including nuclear medicine therapy, CT examinations, x-ray radiological image optimization, nuclear medicine imaging, external photon and proton treatments, and management of respiration in modern image-guided radiation treatment Patient-specific phantoms used for radiation treatment planning involving two Monte Carlo code systems: GEANT4 and EGS Future needs for research and development Related data sets are available for download on the authors’ website. The breadth and depth of this work enables readers to obtain a unique sense of the complete scientific process in computational phantom development, from the conception of an idea, to the identification of original anatomical data, to solutions of various computing problems, and finally, to the ownership and sharing of results in this groundbreaking field that holds so much promise.