Pulmonary Biology in Health and Disease

Author: Edward E. Bittar
Publisher: Springer Science & Business Media
ISBN: 0387224351
Format: PDF, ePub, Docs
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Pulmonary Biology in Health and Disease was conceived as a companion to a handful of expensive, multivolume textbooks. This is part of the promising trend to publish shorter textbooks on the subjects of lung biology and remodeling. Whoever is familiar with human biology and the far-reaching consequences of the genome and postgenome revolutions is apt to concede that the centerpiece in remodeling lies in the ?eld of m- ecular cardiobiology. The ?eld of molecular cardiobiology includes the syndrome of chronic heart failure as well as ischemic cardioprotection. By analogy, the centerpiece in pulmonobiology is chronic asthma. Key topics in the present volume include s- naling mechanisms regulating the endothelium and smooth muscle cells,in?ammatory cells, mediators, airway surface liquid, and pharmacological therapy that focuses on how in?amed airways are altered. Written primarily for predoctoral and postdoctoral graduates in the basic medical sciences, the medical student and postdoctoral physician, graduates in the allied s- ences, nurses, pulmonologists, and physicians in critical care medicine, this book p- vides many of the fundamentals of contemporary pulmonology. It is divided into several parts devoted to the control of respiration, arterial chemoreceptors,muscles of ventilation, pulmonary physiology, and gas exchange in health, exercise, and disease. Special emphasis is placed on emphysema and its pathobiology, acute lung injury, asthma and inhaled toxicants. Because the ?eld is always evolving, each chapter includes recommended readings that lead the reader to sources of additional information, such as the review on remodeling of the blood gas barrier by West and Mathieu-Costello.

Pulmonary and Peripheral Gas Exchange in Health and Disease

Author: Josep Roca
Publisher: Marcel Dekker
ISBN: 9780824703356
Format: PDF, Mobi
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Featuring a comprehensive analysis of gas exchange in healthy and diseased states and addressing functions of peripheral gas delivery, this detailed reference presents an interdisciplinary approach to understanding and studying oxygen transport throughout the body. More than 30 internationally renowned experts combine techniques from clinical medicine, pathophysiology, and therapy to deliver the latest research in an integrative manner on pulmonary gas exchange in the body. Pulmonary and Peripheral Gas Exchange in Health and Disease examines the effects of damaged lungs and the abnormal functions of body tissues and organs on pulmonary circulation reviews the behavior and mechanisms of gas exchange in the heart, skeletal muscle, gut, brain, and kidneys describes the requirements and behavior of homeostasis investigates conditions in normal physiology-during exercise, and at sea level, high altitude, and microgravity analyzes the performance of gas exchange in bronchial asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and acute respiratory disease syndrome highlights peripheral transport of oxygen from the capillaries into the mitochondria targets prescient directions for future research and more! Containing over 2800 literature references, drawings, photographs, and equations, Pulmonary and Peripheral Gas Exchange in Health and Disease makes an excellent reference for pulmonologists; physiologists; anesthesiologists; chest, intensive care, thoracic, and emergency room physicians; and medical school students in these disciplines.

The Pulmonary Epithelium in Health and Disease

Author: David Proud
Publisher: John Wiley & Sons
ISBN: 9780470727003
Format: PDF, ePub, Mobi
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"This is essential reading for everyone who would like to update their knowledge of the pulmonary epithelium. It offers a comparison between laboratory animal models and human lungs, highlighting the differences and the similarities between the two, which will be particularly useful to researchers." –Doody's, April 2009 The past two decades have seen extraordinary advances in our understanding of the role of the pulmonary epithelium in airway health and disease. Our understanding of epithelial biology has expanded exponentially in the past decade. This book provides a unique comprehensive description of the structure of the epithelium, its damage by various agents and the mechanism of epithelial repair. In addition, it's detailed coverage includes not only the multiple ways in which the epithelium contributes to host defence, but also the nature and functional consequences of the interactions of inhaled pathogens, including viruses, bacteria, allergens and pollutants. the role of the epithelium in regulating airway inflammation and structure is also discussed, as is the role of the epithelium as a target for inhaled medications and as a route for novel drug delivery. Containing chapters on multiple aspects of epithelial function in health and disease, each one is written by a leader in the field. This is essential reading for pulmonary researchers and physicians requiring detailed advanced understanding of the epithelium as well as those working in allergy, biomedical and pharmaceutical research.

Practical Pulmonary and Critical Care Medicine

Author: Zab Mosenifar
Publisher: CRC Press
ISBN: 9780849374470
Format: PDF, ePub
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Including previously unpublished guidelines and recent care descriptions not available in any other text, this reference provides illustrative chapters on the identification, diagnosis, and management of commonly encountered diseases and conditions in the care of the critically-ill patient. Researching the most recent clinical trials and supplying a extensive amount of tables, references, and figures, this guide examines issues significantly affecting the efficacy of care in the ICU, such as nutritional formulations, sedation methods, pain control, life-support technology, and the electronic health record.

Exercise

Author: Brian J. Whipp
Publisher: Informa Health Care
ISBN: 9780824782306
Format: PDF, ePub, Mobi
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Fifteen contributed chapters deal with the major aspects of the effects of exercise on the respiratory system in health and disease. The chapters are organized into a logically sequential scheme of topics: beginning with pulmonary mechanics; continuing with pulmonary gas exchange, the pulmonary and

Proteoglycans in Lung Disease

Author: Hari G. Garg
Publisher: CRC Press
ISBN: 9780824743666
Format: PDF, Docs
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Discusses new treatment strategies for malignant mesothelioma, pulmonary edema, fibrosis, asthma, emphysema, and bronchiectasis. Proteoglycans in Lung Disease considers glycosaminoglycans as novel therapeutic agents or targets in lung disease the role of proteoglycans in determining mechanical behavior of lung tissue hyaluronan and its receptors in wound healing, inflammation, vasculogenesis, and angiogenesis the impact of small proteoglycans on matrix assembly versican as a modulator of cell adhesion, migration, and proliferation antiproliferative activity of heparin and its derivatives on pulmonary artery smooth muscle cells the effects of mechanical strain on proteoglycans the functions of proteoglycans in the vascular wall the effect of hypoxia on glycosaminoglycans in the lung Comprised of more than 1940 references, Proteoglycans in Lung Disease

Respiratory Circulatory Interactions in Health and Disease

Author: Steven M. Scharf
Publisher: CRC Press
ISBN: 9780824741747
Format: PDF, ePub
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This book describes the basic, pathophysiologic, and clinical importance of the reciprocal relationships and interactions between the respiratory and cardiovascular systems, examining mechanical responses caused by lung volume and thoracic pressure. Emphasizes humoral and neurophysical interactions occurring in diseases that lead to cardiorespiratory failure. Covering pulmonary mechanics, respiratory muscle function, exercise physiology, and control of venous return and cardiac output, Respiratory-Circulatory Interactions in Health and Disease focuses on mechanisms of heart failure in respiratory disease details the central interactions in sudden infant death syndrome considers the control of tissue metabolism, the development of the sympathetic nervous system, mathematical modeling, and image analysis as a tool for investigating cardiocirculatory function examines the effects of muscle reflexes on respiration and circulation analyzes systemic inflammatory response and chronic obstructive lung disease discusses respiratory maneuvers to support failing circulation and ventilation addresses current controversies surrounding the balloon-tipped catheter debates using inhaled nitrous oxide to treat circulatory failure and more! Supplying a rational basis for understanding the ways in which the cardiovascular and respiratory systems interact in normal and abnormal situations, Respiratory-Circulatory Interactions in Health and Disease is a blue-ribbon reference for cardiologists; pulmonologists; physiologists; intensivists; cardiothoracic surgeons; anesthesiologists; asthmatologists; health care practitioners interested in chest, pulmonary, and thoracic medicine; and medical school students in these disciplines.

The Pulmonary Endothelium

Author: Norbert Voelkel
Publisher: John Wiley & Sons
ISBN: 9780470747506
Format: PDF
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The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals – specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.

Gene Therapy in Lung Disease

Author: Steven M. Albeda
Publisher: CRC Press
ISBN: 0824743636
Format: PDF
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Presents up-to-date summaries of recently completed and ongoing clinical trials. With writings from more than 35 internationally renowned experts, Gene Therapy in Lung Disease unlocks the biological mysteries of infection immunity cytokine behavior fibrosis and illustrates the use of gene therapy to treat lung cancer mesothelioma cystic fibrosis pulmonary vascular diseases a1-antitrypsin deficiency acute lung injury lung transplant rejection Containing over 2230 references, Gene Therapy in Lung Disease is designed for pulmonologists and pulmonary disease specialists, geneticists, physiologists, biochemists, molecular and cell biologists, pediatricians, pathologists, pharmaceutical industry scientists, primary care physicians, and graduate-level and medical school students in these disciplines.