Radiation Hormesis and the Linear No Threshold Assumption

Author: Charles L. Sanders
Publisher: Springer Science & Business Media
ISBN: 9783642037207
Format: PDF, Mobi
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Current radiation protection standards are based upon the application of the linear no-threshold (LNT) assumption, which considers that even very low doses of ionizing radiation can cause cancer. The radiation hormesis hypothesis, by contrast, proposes that low-dose ionizing radiation is beneficial. In this book, the author examines all facets of radiation hormesis in detail, including the history of the concept and mechanisms, and presents comprehensive, up-to-date reviews for major cancer types. It is explained how low-dose radiation can in fact decrease all-cause and all-cancer mortality and help to control metastatic cancer. Attention is also drawn to biases in epidemiological research when using the LNT assumption. The author shows how proponents of the LNT assumption consistently reject, manipulate, and deliberately ignore an overwhelming abundance of published data and falsely claim that no reliable data are available at doses of less than 100 mSv.

Radiobiology and Radiation Hormesis

Author: Charles L. Sanders
Publisher: Springer
ISBN: 3319563726
Format: PDF, Docs
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This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives.

Underexposed

Author: Ed Hiserodt
Publisher: BookBaby
ISBN: 1483509087
Format: PDF, Mobi
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There is a very large disconnect between the actual dangers of exposure to low doses of ionizing radiation and the fears of such exposure. A tiny leak at a nuclear power plant is front page news, while there has never been a death or even an injury to the public from escaping radiation. Meanwhile 50,000 deaths from auto accidents go almost unnoticed. This fear is particularly ironic since hundreds of studies show that low doses of ionizing radiation result is lower cancer rates and overall mortality. One of these studies examined in some detail was done by Johns-Hopkins involving an initial pool of 700,000 workers, some of whom worked on ships with nuclear propulsion, while others (randomly selected) were employed on non-nuclear ships. The nuclear workers had a standard mortality rate of 0.76 times that of non-nuclear workers. In largest "ecological" study in history, Professor Bernard Cohen of Pittsburgh University was attempting to correlate level of residential radon with lung cancer. He was astonished to find that the opposite was true -- the more radon, the less cancer. Of course these data, from 1,729 counties (about 90% of the U.S.), didn't faze the Environmental Protection Agency that has continued its crusade against radon exposure. The positive benefits of low doses of radiation is known as "hormesis" and is identified in over 150 studies and other documented evidence presented in the book.

Radiation Dose from Adult and Pediatric Multidetector Computed Tomography

Author: D. Tack
Publisher: Springer Science & Business Media
ISBN: 9783540685753
Format: PDF, Docs
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This book considers in depth all the factors that influence the radiation dose and the risk associated with MDCT in children and adults. Only a small proportion of referring clinicians, radiologists, and technologists are aware of both the radiation risks and their underlying mechanisms. The book proposes detailed guidelines for optimization of the radiation dose when using MDCT. It is written by experts of international standing.

Hormesis

Author: Mark P. Mattson
Publisher: Springer Science & Business Media
ISBN: 9781607614951
Format: PDF, Mobi
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Hormesis is a poorly understood phenomenon affecting all forms of life on earth. This groundbreaking book summarizes and analyzes the various positives of hormesis in an attempt to reveal hormesis as a fundamental principle of biomedical sciences as a whole.

Health Risks from Exposure to Low Levels of Ionizing Radiation

Author: Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher: National Academies Press
ISBN: 0309133343
Format: PDF, Kindle
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This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies

Author: Michael Molls
Publisher: Springer Science & Business Media
ISBN: 3540743863
Format: PDF, Docs
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Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.

Carcinoma of the Bladder

Author: Zbigniew Petrovich
Publisher: Springer Science & Business Media
ISBN: 3642602584
Format: PDF, ePub
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Concentrating on the diagnosis and treatment of carcinoma of the bladder, rather than the entire field of genitourinary oncology, this book discusses in depth all the important advances in molecular genetics of relevance to clinical practice. Progress in both imaging and non-imaging modalities from recent clinical trials is well documented and critically evaluated in a manner that will prove invaluable for practising urooncologists. Furthermore, the management of patients with superficial, muscle-invasive, and advanced disease is discussed, and new treatment results presented. Numerous illustrations and tables serve to assist in understanding the data presented.

Radiation Therapy Physics

Author: Alfred R. Smith
Publisher: Springer Science & Business Media
ISBN: 3662031078
Format: PDF, Mobi
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The aim of this book is to provide a uniquely comprehensive source of information on the entire field of radiation therapy physics. The very significant advances in imaging, computational, and accelerator technologies receive full consideration, as do such topics as the dosimetry of radiolabeled antibodies and dose calculation models. The scope of the book and the expertise of the authors make it essential reading for interested physicians and physicists and for radiation dosimetrists.