Risk Assessment with Time to Event Models

Author: Mark Crane
Publisher: CRC Press
ISBN: 1420032283
Format: PDF
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How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions. Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50. The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.

Ecological Risk Assessment for Contaminated Sites

Author: Glenn W. Suter II
Publisher: CRC Press
ISBN: 9781420056693
Format: PDF, Kindle
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Love Canal. Exxon Valdez. Times Beach. Sacramento River Spill. Amoco Cadiz. Seveso. Every area of the world has been affected by improper waste disposal and chemical spills. Common hazardous waste sites include abandoned warehouses, manufacturing facilities, processing plants, and landfills. These sites poison the land and contaminate groundwater and drinking water. A sequel to the bestselling Ecological Risk Assessment, Ecological Risk Assessment for Contaminated Sites focuses on how to perform ecological risk assessments for Superfund sites and locations contaminated by improper disposal of wastes, or chemical spills. It integrates the authors' extensive experience in assessing ecological risks at U.S. government sites with techniques and examples from assessments performed by others. Conducting an ecological risk assessment on a contaminated site provides the information needed to make decisions concerning site remediation. The first rule of good risk assessment is "don't do anything stupid". With the practical preparation you get from Ecological Risk Assessment for Contaminated Sites you won't.

Ecological Risk Assessment for Chlorpyrifos in Terrestrial and Aquatic Systems in the United States

Author: John P. Giesy
Publisher: Springer Science & Business Media
ISBN: 3319038656
Format: PDF, ePub, Docs
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Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications.

Population Level Ecological Risk Assessment

Author: Lawrence W. Barnthouse
Publisher: CRC Press
ISBN: 9781420053333
Format: PDF, Mobi
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Most ecological risk assessments consider the risk to individual organisms or organism-level attributes. From a management perspective, however, risks to population-level attributes and processes are often more relevant. Despite many published calls for population risk assessment and the abundance of available scientific research and technical tools assessing risks to populations, risk assessors worldwide still have difficulty determining how population level considerations can be integrated into environmental decision-making. Population-Level Ecological Risk Assessment establishes a framework for goals, methods, and data needs for different assessment applications and for integrating population-level risk assessment into risk management decisions. Beginning with a summary of legal, regulatory, business, and other contexts, the book presents population-level ecological risk assessment as an internationally recognized, science-based tool and offers specific recommendations for using this tool to support environmental management decisions. It gives clear, explicit, operational population assessment definitions and explains the relevance of density dependence, genetics, and spatial considerations, as well as applicable lessons from conservation biology and natural resource management. The authors provide a "tool box" of empirical and modeling methods and describe the general approaches, assumptions, data requirements, strengths, and limitations of each method. They establish a working foundation for designing and conducting population-level ecological risk assessments consistent with North American, European, and Japanese risk management approaches. The book concludes by highlighting key considerations needed to improve the scientific quality and interpretation of assessments. Detailed appendices include examples of population-level assessment approaches applicable to specific environmental management contexts, a modeling case study, and a supplemental reading list.

Ecological Risk Assessment Second Edition

Author: Glenn W. Suter II
Publisher: CRC Press
ISBN: 1420012568
Format: PDF, Docs
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The definitive reference in its field, Ecological Risk Assessment, Second Edition details the latest advances in science and practice. In the fourteen years since the publication of the best-selling first edition, ecological risk assessment (ERA) has moved from the margins into the spotlight. It is now commonly applied to the regulation of chemicals, the remediation of contaminated sites, the monitoring of importation of exotic organisms, the management of watersheds, and other environmental management issues. Delineating the processes for performing an ERA, the book begins by defining the field, then goes on to describe its relationship to other environmental assessment practices and its organizational framework. The book also includes a chapter on ecological epidemiology, which has previously been treated as a type of ERA, but is now recognized as a distinct practice in itself. It explores important concepts in the ERA process including probability, uncertainty, scale, mode of action and multiple causes. Reflecting changes in the field, the book’s scope has been broadened to include discussions of the application of ERA to agents other than chemical contaminants. The multitude of illustrative figures provides a flavor for the diverse practice of ERA. The author has re-organized the material, presenting a unitary process of ERA that is applicable to various problems, scales, and mandates. He keeps the emphasis squarely on providing clear, scientifically sound, and unbiased technical advice on the risks from chemicals and chemical mixtures.

Exposure Science in the 21st Century

Author: Committee on Human and Environmental Exposure Science in the 21st Century
Publisher: National Academies Press
ISBN: 0309264685
Format: PDF
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From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day--many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies--including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics--have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Science and Decisions

Author: Committee on Improving Risk Analysis Approaches Used by the U.S. EPA
Publisher: National Academies Press
ISBN: 0309120462
Format: PDF, ePub, Docs
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Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Risk Assessment Methods

Author: V.T. Covello
Publisher: Springer Science & Business Media
ISBN: 1489912169
Format: PDF, Mobi
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Much has already been written about risk assessment. Epidemiologists write books on how risk assessment is used to explore the factors that influence the distribution of disease in populations of people. Toxicologists write books on how risk assess ment involves exposing animals to risk agents and concluding from the results what risks people might experience if similarly exposed. Engineers write books on how risk assessment is utilized to estimate the risks of constructing a new facility such as a nuclear power plant. Statisticians write books on how risk assessment may be used to analyze mortality or accident data to determine risks. There are already many books on risk assessment-the trouble is that they all seem to be about different sUbjects! This book takes another approach. It brings together all the methods for assessing risk into a common framework, thus demonstrating how the various methods relate to one another. This produces four important benefits: • First, it provides a comprehensive reference for risk assessment. This one source offers readers concise explanations of the many methods currently available for describing and quantifying diverse types of risks. • Second, it consistently evaluates and compares available risk assessment methods and identifies their specific strengths and limitations. Understand ing the limitations of risk assessment methods is important. The field is still in its infancy, and the problems with available methods are disappoint ingly numerous. At the same time, risk assessment is being used.