Static Headspace Gas Chromatography

Author: Bruno Kolb
Publisher: John Wiley & Sons
ISBN: 0471914568
Format: PDF, Kindle
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The only reference to provide both current and thorough coverage of this important analytical technique Static headspace-gas chromatography (HS-GC) is an indispensable technique for analyzing volatile organic compounds, enabling the analyst to assay a variety of sample matrices while avoiding the costly and time-consuming preparation involved with traditional GC. Static Headspace-Gas Chromatography: Theory and Practice has long been the only reference to provide in-depth coverage of this method of analysis. The Second Edition has been thoroughly updated to reflect the most recent developments and practices, and also includes coverage of solid-phase microextraction (SPME) and the purge-and-trap technique. Chapters cover: * Principles of static and dynamic headspace analysis, including the evolution of HS-GC methods and regulatory methods using static HS-GC * Basic theory of headspace analysis-physicochemical relationships, sensitivity, and the principles of multiple headspace extraction * HS-GC techniques-vials, cleaning, caps, sample volume, enrichment, and cryogenic techniques * Sample handling * Cryogenic HS-GC * Method development in HS-GC * Nonequilibrium static headspace analysis * Determination of physicochemical functions such as vapor pressures, activity coefficients, and more Comprehensive and focused, Static Headspace-Gas Chromatography, Second Edition provides an excellent resource to help the reader achieve optimal chromatographic results. Practical examples with original data help readers to master determinations in a wide variety of areas, such as forensic, environmental, pharmaceutical, and industrial applications.

Handbook of GC MS

Author: Hans-Joachim Hübschmann
Publisher: John Wiley & Sons
ISBN: 352731427X
Format: PDF, Docs
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The most important advantage [of this text] is that it has not only been written for the practitioner, but also the analyst who wishes to familiarize himself with any or all the aspects of GC/MS' - AFS - Advances In Food Sciences. This is an updated edition of its bestselling predecessor, Handbook of GC/MS: Fundamentals and Applications that offers broad coverage of the subject, from sample preparation to the evaluation of MS-Data. This edition boasts several new chapters, including Automated Solvent Extraction (ASE), Hyphenation with Isotope Ratio MS, and the TOF-technique

Modern Practice of Gas Chromatography

Author: Robert L. Grob, PhD
Publisher: John Wiley & Sons
ISBN: 9780471651154
Format: PDF
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The bible of gas chromatography-offering everything the professional and the novice need to know about running, maintaining, and interpreting the results from GC Analytical chemists, technicians, and scientists in allied disciplines have come to regard Modern Practice of Gas Chomatography as the standard reference in gas chromatography. In addition to serving as an invaluable reference for the experienced practitioner, this bestselling work provides the beginner with a solid understanding of gas chromatographic theory and basic techniques. This new Fourth Edition incorporates the most recent developments in the field, including entirely new chapters on gas chromatography/mass spectrometry (GC/MS); optimization of separations and computer assistance; high speed or fast gas chromatography; mobile phase requirements: gas system requirements and sample preparation techniques; qualitative and quantitative analysis by GC; updated information on detectors; validation and QA/QC of chromatographic methods; and useful hints for good gas chromatography. As in previous editions, contributing authors have been chosen for their expertise and active participation in their respective areas. Modern Practice of Gas Chromatography, Fourth Edition presents a well-rounded and comprehensive overview of the current state of this important technology, providing a practical reference that will greatly appeal to both experienced chomatographers and novices.

Gas Chromatography and Mass Spectrometry A Practical Guide

Author: O. David Sparkman
Publisher: Academic Press
ISBN: 9780080920153
Format: PDF, ePub, Docs
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The second edition of Gas Chromatography and Mass Spectrometry: A Practical Guide follows the highly successful first edition by F.G. Kitson, B.S. Larsen, and C.N. McEwen (1996), which was designed as an indispensible resource for GC/MS practitioners regardless of whether they are a novice or well experienced. The Fundamentals section has been extensively reworked from the original edition to give more depth of an understanding of the techniques and science involved with GC/MS. Even with this expansion, the original brevity and simple didactic style has been retained. Information on chromatographic peak deconvolution has been added along with a more in-depth understanding of the use of mass spectral databases in the identification of unknowns. Since the last edition, a number of advances in GC inlet systems and sample introduction techniques have occurred, and they are included in the new edition. Other updates include a discussion on fast GC and options for combining GC detectors with mass spectrometry. The section regarding GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types has the same number of compound types as the original edition, but the information in each section has been expanded to not only explain some of the spectra but to also explain why certain fragmentations take place. The number of Appendices has been increased from 12 to 17. The Appendix on Atomic Masses and Isotope Abundances has been expanded to provide tools to aid in determination of elemental composition from isotope peak intensity ratios. An appendix with examples on "Steps to follow in the determination of elemental compositions based on isotope peak intensities" has been added. Appendices on whether to use GC/MS or LC/MS, third-party software for use in data analysis, list of information required in reporting GC/MS data, X+1 and X+2 peak relative intensities based on the number of atoms of carbon in an ion, and list of available EI mass spectral databases have been added. Others such as the ones on derivatization, isotope peak patterns for ions with Cl and/or Br, terms used in GC and in mass spectrometry, and tips on setting up, maintaining and troubleshooting a GC/MS system have all been expanded and updated. Covers the practical instruction necessary for successful operation of GC/MS equipment Reviews the latest advances in instrumentation, ionization methods, and quantitation Includes troubleshooting techniques and a variety of additional information useful for the GC/MS practitioner A true benchtop reference A guide to a basic understanding of the components of a Gas Chromatograph-Mass Spectrometer (GC-MS) Quick References to data interpretation Ready source for information on new analyses

Handbook of Chemical and Biological Plant Analytical Methods 3 Volume Set

Author: Shilin Chen
Publisher: John Wiley & Sons
ISBN: 1118874986
Format: PDF, Kindle
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Plants and plant-derived compounds and drugs are becoming more and more popular with increasing numbers of scientists researching plant analysis. The quality control of herbal drugs is also becoming essential to avoid severe health problems, and in the future many more new drugs will be developed from plant sources. This three-volume Handbook, featuring 47 detailed review articles, is unique as it deals with chemical and biological methodologies for plant analysis. It presents the most important and most accurate methods which are available for plant analysis. This comprehensive work is divided into six sections as follows: Sample preparation and identification – discussing plant selection and collection, followed by extraction and sample preparation methodologies. Extraction and sample preparation methodologies Instrumentation for chemical analysis - several instrumentations for chemical plant analysis are presented with an emphasis on hyphenated techniques, e.g. the coupling between HPLC and mass spectroscometry, and HPLC with NMR. Strategies for selective classes of compounds – coverage of the most interesting classes of compounds such as polysaccharides, saponins, cardiotonic glycosides, alkaloids, terpenoids, lipids, volatile compounds and polyphenols ( flavonoids, xanthones, coumarins, naphthoquinones, anthraquinones, proanthocyanidins, etc.). Biological Analysis - includes phenotyping, DNA barcoding techniques, transcriptome analysis , microarray, metabolomics and proteomics. Drugs from Plants – covers the screening of plant extracts and strategies for the quick discovery of novel bioactive natural products. Safety assessment of herbal drugs is highly dependent on outstanding chromatographic and spectroscopic methods which are also featured here. This Handbook introduces to scientists involved in plant studies the current knowledge of methodologies in various fields of chemically- and biochemically-related topics in plant research. The content from this Handbook will publish online within the Encyclopedia of Analytical Chemistry via Wiley Online Library: http://www.wileyonlinelibrary.com/ref/eac Benefit from the introductory offer, valid until 30 November 2014! Introductory price: £425.00 / $695.00 / €550.00 List price thereafter: £495.00 / $795.00 / €640.00

Analytical Chemistry in a GMP Environment

Author: James M. Miller
Publisher: Wiley-Interscience
ISBN: 9780471314318
Format: PDF
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How to hone your analytical skills and obtain high-quality data in the era of GMP requirements With increased regulatory pressures on the pharmaceutical industry, there is a growing need for capable analysts who can ensure appropriate scientific practices in laboratories and manufacturing sites worldwide. Based on Johnson & Johnson's acclaimed in-house training program, this practical guide provides guidance for laboratory analysts who must juggle the Food and Drug Administration's good manufacturing practices (GMP) rules with rapidly changing analytical technologies. Highly qualified industry experts walk readers step-by-step through the concepts, techniques, and tools necessary to perform analyses in an FDA-regulated environment, including clear instructions on all major analytical chemical methods-from spectroscopy to chromatography to dissolution. An ideal manual for formal training as well as an excellent self-study guide, Analytical Chemistry in a GMP Environment features: * The drug development process in the pharmaceutical industry * Uniform and consistent interpretation of GMP compliance issues * A review of the role of statistics and basic topics in analytical chemistry * An emphasis on high-performance liquid chromatographic (HPLC) methods * Chapters on detectors and quantitative analysis as well as data systems * Methods for ensuring that instruments meet standard operating procedures (SOP) requirements * Extensive appendixes for unifying terms, symbols, and procedural information

Basic gas chromatography

Author: Harold Monroe McNair
Publisher: Wiley-Interscience
ISBN: 9780471172604
Format: PDF
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* Briefly covers GC-MS, headspace analysis, chiral analysis, solid phase microextraction, and other cutting-edge topics.

Additives in Polymers

Author: Jan C. J. Bart
Publisher: Wiley
ISBN: 9780470850626
Format: PDF, Kindle
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This industrially relevant resource covers all established and emerging analytical methods for the deformulation of polymeric materials, with emphasis on the non-polymeric components. Each technique is evaluated on its technical and industrial merits. Emphasis is on understanding (principles and characteristics) and industrial applicability. Extensively illustrated throughout with over 200 figures, 400 tables, and 3,000 references.