Thalassaemia The Biography

Author: David Weatherall
Publisher: OUP Oxford
ISBN: 9780191614163
Format: PDF
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Thalassaemia is the most common type of genetic disorder in the human population, and one of the first whose genetic basis was established. Written by Sir David Weatherall, an expert in molecular medicine and the founder of the Institute of Molecular Medicine in Oxford, this tells the story of early reports of the disease, historical accounts, the identification of the disease as having an inherited basis, early work on thalassaemia as a disorder of the synthesis of haemoglobin, and from the 1960s with the rise of molecular biology, the study of the condition at the DNA level. The commonality of the disease raised an important evolutionary question: if thalassaemia is a genetic disorder then why hasn't it been selected out? Why does it persist, especially in Mediterranean populations? The great geneticist JBS Haldane suggested a reason - that carriers might be more resistant to malaria. Now that we have much more detailed understanding of the molecular basis of this set of diseases, has Haldane proved to be right? Weatherall shows that Haldane turns out to have been partially right. The book ends with recent improvements in treatment that have transformed patients' lives and a general assessment of how molecular approaches are impacting on medicine. Thalassaemia: the biography is part of the Oxford series, Biographies of Disease, edited by William and Helen Bynum. In each individual volume an expert historian of medicine tells the story of a particular disease or condition throughout history - not only in terms of growing medical understanding of its nature and cure, but also shifting social and cultural attitudes, and changes in the meaning of the name of the disease itself.

Identity and Health

Author: David Kelleher
Publisher: Psychology Press
ISBN: 9780415307918
Format: PDF, ePub, Mobi
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Experiences of health and illness are fundamental to how we understand ourselves, and the postmodern obsession with body image has made health even more significant in identity formation. The study of subjective experiences of health and illness can also provide a challenge to traditional objective medical knowledge and, given current healthcare interest in user involvement, can highlight the need for change in health service provision. This book explores the interplay between identity and health, private and public, mind and body. Drawing on new material, and using and exploring innovative biographical and narrative methods, it covers a broad range of identities in relation to health and illness, including race, religion, ethnicity, disability, age, body image, sexuality and gender. Identity and Health will be of great interest to academics, researchers and students of sociology, medical anthropology, health and psychology.