Toxicology of the Lung Fourth Edition

Author: Donald E. Gardner
Publisher: CRC Press
ISBN: 9781616310202
Format: PDF, ePub, Mobi
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The most up-to-date treatment of inhalation toxicology available, Toxicology of the Lung, Fourth Edition examines the subject from a target-organ perspective. Completely revised and updated, the book includes contributions from an entirely new set of authors, each of them a leading international authority in their respective specialties. As with the previous editions, it presents the latest advances in our knowledge of how the lung responds to airborne contaminants. It discusses the assessment of nanomaterials, pulmonary administration of new therapeutics, health effects of inhaled particulate matter from diesel exhaust, and respiratory genomics. The new edition provides insight into current thinking about the critical need for understanding the kinetics and dynamic interactions associated with toxic effects. It explores the appropriateness of recent advances made across disciplines and addresses human clinical testing and emerging technology for using animal and in vitro models to detect adverse effects. The book examines how airborne substances can alter the physiological, biochemical, and morphological functioning of biological systems and covers the latest modeling approaches for predicting deposition and fate of inhaled particles. Illustrating on-going research efforts for delineating the association between airborne substances and systemic effects, the book provides authoritative reviews of selected areas. The editor makes the information accessible to readers who do not have a background in pulmonary physiology without sacrificing the scientific rigor required by those who do. These features make this the ultimate resource on how pollutants affect allergies, infection, and other lung diseases.

Toxicology of the Lung Fourth Edition

Author: Donald E. Gardner
Publisher: CRC Press
ISBN: 1616310200
Format: PDF, ePub
Download Now
The most up-to-date treatment of inhalation toxicology available, Toxicology of the Lung, Fourth Edition examines the subject from a target-organ perspective. Completely revised and updated, the book includes contributions from an entirely new set of authors, each of them a leading international authority in their respective specialties. As with the previous editions, it presents the latest advances in our knowledge of how the lung responds to airborne contaminants. It discusses the assessment of nanomaterials, pulmonary administration of new therapeutics, health effects of inhaled particulate matter from diesel exhaust, and respiratory genomics. The new edition provides insight into current thinking about the critical need for understanding the kinetics and dynamic interactions associated with toxic effects. It explores the appropriateness of recent advances made across disciplines and addresses human clinical testing and emerging technology for using animal and in vitro models to detect adverse effects. The book examines how airborne substances can alter the physiological, biochemical, and morphological functioning of biological systems and covers the latest modeling approaches for predicting deposition and fate of inhaled particles. Illustrating on-going research efforts for delineating the association between airborne substances and systemic effects, the book provides authoritative reviews of selected areas. The editor makes the information accessible to readers who do not have a background in pulmonary physiology without sacrificing the scientific rigor required by those who do. These features make this the ultimate resource on how pollutants affect allergies, infection, and other lung diseases.

Lu s Basic Toxicology

Author: Byung-Mu Lee
Publisher: CRC Press
ISBN: 1841849545
Format: PDF, Kindle
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This new edition of our bestselling book, Lu’s Basic Toxicology, provides a number of key benefits that make it a must-read for toxicology specialists worldwide, including: Revision of a Bestseller - the new Sixth Edition provides the critical updates toxicologists need to keep up with the changing times New Information - on over-the-counter preparations, lactation, and occupational toxicology, providing clarity and insight into a rapidly evolving subject Comprehensive - Updated, topical additions - new chapters on Nanotoxicology and Toxicity of Endocrine System provide you with information not currently available elsewhere Expert Editors - Kacew & Lee offers a distillation of decades and research and teaching experience in toxicology, providing authoritative guidance for both students and practicing professionals Practical- Easy to read information at your fingertips - In-depth, yet concise presentation of material – split into four key sections that include separate subject and chemical indexes all while in the 6 x 9 format makes this a useful, quick pocket-guide for the more experienced researcher.

Cardiovascular Toxicology Fourth Edition

Author: Daniel Acosta
Publisher: CRC Press
ISBN: 1420044745
Format: PDF, Mobi
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Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function. New developments include: expanded chapter on passive smoking, which includes adverse effects of smoking, and the effects of secondary smoke new chapter on the negative effects from environmental chemicals on the cardiovascular system chapters covering antibacterial agents and endotoxins include new information on cardiovascular toxicity of antimicrobials, as well as anti-viral agents, antibacterial agents, and other agents

Information Resources in Toxicology

Author: P.J. Bert Hakkinen
Publisher: Academic Press
ISBN: 9780080920030
Format: PDF
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This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the “hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. • International in scope, with contributions from over 30 countries • Numerous key references and relevant Web links • Concise narratives about toxicologic sub-disciplines • Valuable appendices such as the IUPAC Glossary of Terms in Toxicology • Authored by experts in their respective sub-disciplines within toxicology

Handbook on the Toxicology of Metals

Author: Gunnar F. Nordberg
Publisher: Academic Press
ISBN: 0123973392
Format: PDF, ePub
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Handbook on the Toxicology of Metals, Fourth Edition bridges the gap between established knowledgebase and new advances in metal toxicology to provide one essential reference for all those involved in the field. This book provides comprehensive coverage of basic toxicological data, emphasizing toxic effects primarily in humans, but also those of animals and biological systems in vitro. The fourth edition also contains several new chapters on important topics such as nanotoxicology, metals in prosthetics and dental implants, gene-environment interaction, neurotoxicology, metals in food, renal, cardiovascular, and diabetes effects of metal exposures and more. Volume I covers “General Considerations and Volume II is devoted to “Specific Metals. A multidisciplinary resource with contributions from internationally-recognized experts, the fourth edition of the Handbook on the Toxicology of Metals is a prominent and indispensable reference for toxicologists, physicians, pharmacologists, engineers, and all those involved in the toxicity of metals. Contains 61 peer reviewed chapters dealing with the effects of metallic elements and their compounds on biological systems Includes information on sources, transport and transformation of metals in the environment and on certain aspects of the ecological effects of metals to provide a basis for better understanding of the potential for adverse effects on human health Covers the toxicology of metallic nanomaterials in a new comprehensive chapter Metal toxicology in developing countries is dealt with in another new chapter emphasizing the adverse effects on human health by the inadequate handling of "ewaste Other new chapters in the 4th edition include: Toxic metals in food; Toxicity of metals released from medical devices; Gene-environment interactions; Neurotoxicology of metals; Cardiovascular disease; Renal effects of exposure to metals; Gold and gold mining; Iridium; Lanthanum; Lithium and Rhodium

Reproductive Toxicology Third Edition

Author: Robert W. Kapp
Publisher: CRC Press
ISBN: 1420073443
Format: PDF, ePub, Docs
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Thoroughly examining the popular and expanding field of reproductive toxicology, this newly revised and expanded third edition provides the latest, cutting-edge scientific developments in this constantly evolving discipline. Reproductive Toxicology’s contributors are experienced regulatory agency and Clinical Research Organization representatives who currently utilize the new techniques discussed in the text and continue to revolutionize reproductive toxicology research. This ground-breaking resource includes: New and important critical mechanistic topics such as epigenetics and omics The first significant compilation of epigenetic mechanisms An in-depth analysis of the role of genomics, proteomics, and metabolomicsin human reproduction New guidelines with respect to the latest research applications in the field

Endocrine Toxicology Third Edition

Author: J. Charles Eldridge
Publisher: CRC Press
ISBN: 142009310X
Format: PDF, ePub
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With contributions by international experts in academia, chemical manufacturing, government research laboratories, regulatory agencies, and private consulting, this guide explores the potentially damaging influence of environmental agents on the endocrine system. It examines endocrine toxicology’s increased importance in environmental safety issues due to legislative directives established over the past ten years. Covering all principal areas of EPA concern, Endocrine Toxicology, Third Edition provides: putative endocrine disruptors and mechanisms of endocrine toxicity the history and status of the regulatory process mechanisms of toxic effects in various hormonal systems comparisons of the endocrine responses in humans, livestock, and wildlife testing methods in mammalian, fish, avian, and amphibian models valuable insight into the approaches of various personnel in the field, including: government officials who make and oversee policy; scientists in charge of development and validation of testing methods; basic researchers who identify toxic mechanisms; and manufacturers responsible for environmentally benign product certification

Toxicology of the Nose and Upper Airways

Author: John B. Morris
Publisher: CRC Press
ISBN:
Format: PDF, ePub, Docs
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The application of molecular biologic methods, recognition of neurogenic inflammatory processes, and utilization of genetic knockout animals are just some of the advances in toxicology of the upper airways in recent years. Toxicology of the Nose and Upper Airways presents a culmination of knowledge gained as a result of both human and experimental animal studies over the past decade. With contributions from internationally recognized leaders in the fields of experimental toxicology, respiratory medicine, otolaryngology, allergy, and sensory science, this volume: Examines the effect of selected pollutants on the upper airways of both humans and experimental animals—emphasizing mechanistic issues in the process Discusses epidemiologic findings from populations exposed occupationally or environmentally, comparing and contrasting alternative risk assessment approaches Features clear chapter organization with sections on structure and function, dosimetry and toxicokinetics, functional and pathologic responses and their measurement, responses to specific agents, risk assessment, and special topics This volume is an essential reference for pharmacologists and toxicologists concerned with the nose and upper airway, as well as clinicians, risk assessors, and sensory scientists.

Information Resources in Toxicology

Author: Philip Wexler
Publisher: Academic Press
ISBN: 0127447709
Format: PDF, Kindle
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Information Resources in Toxicology, Third Edition is a sourcebook for anyone who needs to know where to find toxicology information. It provides an up-to-date selective guide to a large variety of sources--books, journals, organizations, audiovisuals, internet and electronic sources, and more. For the Third Edition, the editors have selected, organized, and updated the most relevant information available. New information on grants and other funding opportunities, physical hazards, patent literature, and technical reports have also been added. This comprehensive, time-saving tool is ideal for toxicologists, pharmacologists, drug companies, testing labs, libraries, poison control centers, physicians, legal and regulatory professionals, and chemists. Key Features * Serves as an all-in-one resource for toxicology information * New edition includes information on publishers, grants and other funding opportunities, physical hazards, patent literature, and technical reports * Updated to include the latest internet and electronic sources, e-mail addresses, etc. * Provides valuable data about the new fields that have emerged within toxicological research; namely, the biochemical, cellular, molecular, and genetic aspects