Understanding Enzymes

Author: Allan Svendsen
Publisher: CRC Press
ISBN: 9814669334
Format: PDF, ePub, Docs
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Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also presents new insights into the mechanistic function and understanding of enzyme reactions, as well as touching upon structural characteristics, including X-ray and nuclear magnetic resonance (NMR) structural methods. A major focus of the book is enzyme molecules’ dependency on dynamic and biophysical environmental impacts on their function in ensembles as well as single molecules. A wide range of readers, including academics, professionals, PhD and master’s students, industry experts, and chemists, will immensely benefit from this exclusive book.

Enzyme Functionality

Author: Allan Svendsen
Publisher: CRC Press
ISBN: 0824756916
Format: PDF, ePub, Docs
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Enzyme Functionality serves as a conduit for trailblazing research in enzyme engineering-relating current understanding of sequence families, the new notion of enzyme structure classes, and modern methods in protein engineering, design, and directed evolution to accelerate the development of novel enzyme functionalities. This reference gathers the diverse perspectives of nearly 80 scientists from around the globe and surveys all leading rational and random approaches to the artificial evolution of enzymes. Citing more than 1500 notable works, it outlines assays for enzyme activity, stability, and specificity and a wide variety of site-directed, redesign, and evolutionary engineering methods.

Dioxygen dependent Heme Enzymes

Author: Masao Ikeda-Saito
Publisher: Royal Society of Chemistry
ISBN: 1782629912
Format: PDF, Kindle
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This book highlights the many and varied catalytic activities of O2-dependent heme-iron enzymes, including monoxygenases and cytochrome P450, dioxygenases, oxidases and model heme systems required for postgraduate students and researchers in biochemistry and metallobiology.

Lipid Modification by Enzymes and Engineered Microbes

Author: Uwe T. Bornscheuer
Publisher: Elsevier
ISBN: 0128131683
Format: PDF, Docs
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Lipid Modification by Enzymes and Engineered Microbes covers the state-of-the art use of enzymes as natural biocatalysts to modify oils, also presenting how microorganisms, such as yeast, can be designed. In the past ten years, the field has made enormous progress, not only with respect to the tools developed for the development of designer enzymes, but also in the metabolic engineering of microbes, the discovery of novel enzyme activities, and in reaction engineering/process development. For the first time, these advances are covered in a single-volume that is edited by leading enzymatic scientist Uwe Borchscheuer and authored by an international team of experts. Identifies how, and when, to use enzymes and microbes for lipid modification Provides enzymatic, microbial and metabolic techniques for lipid modification Covers lipases, acyltransferases, phospholipases, lipoxygenases, monooxygenases, isomerases and sophorolipids Includes lipid modification for use in food, biofuels, oleochemicals and polymer precursors

Improving and Tailoring Enzymes for Food Quality and Functionality

Author: Rickey Yada
Publisher: Elsevier
ISBN: 1782422978
Format: PDF, ePub
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Improving and Tailoring Enzymes for Food Quality and Functionality provides readers with the latest information on enzymes, a biological processing tool that offers the food industry a unique means to control and tailor specific food properties. The book explores new techniques in the production, engineering, and application of enzymes, covering sourcing, isolation, and production of enzymes for food applications. In addition, chapters include detailed discussions of enzyme processing, analytical and diagnostic applications of enzymes in the food industry, and enzyme applications in specific food commodities. Provides readers with the latest information on enzymes and their unique applications in the food industry Explores new techniques in the production, engineering, and application of enzymes, covering sourcing, isolation, and production of enzymes for food applications Chapters include detailed discussions of enzyme processing, engineering and analytical and diagnostic applications of enzymes in the food industry, and enzyme applications in specific food commodities

Introduction to Chemical Engineering Analysis Using Mathematica

Author: Henry C. Foley
Publisher: Elsevier
ISBN: 0080534953
Format: PDF, Docs
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This book provides an introduction to chemical engineering analysis- which reviews the processes and designs used to manufacture, use, and dispose of chemical products-and to Mathematica, one of the most powerful mathematical software tools available for symbolic, numerical, and graphical computing. Analysis and computation are explained simultaneously. The book covers the core concepts of chemical engineering, ranging from the conservation of mass to chemical kinetics. At the same time the text shows how to use the latest version of Mathematica, from the basics of writing a few lines of code through developing entire analysis programs.

Biotechnology for Fuels and Chemicals

Author: Brian H. Davison
Publisher: Springer Science & Business Media
ISBN: 1461223121
Format: PDF, Mobi
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BRIAN H. DAVISON Oak Ridge National Laboratory MARK FINKELSTEIN National Renewable Energy Laboratory CHARLES E. WYMAN Oak Ridge National Laboratory The Eighteenth Symposium on Biotechnology for Fuels and Chemi cals continues to provide a forum for the presentation of research results and the exchange of ideas on advances in biotechnology for the produc tion of fuels and chemicals. Although the emphasis is on utilization of renewable resources, the scope of the Symposium is broader than this and includes bioconversion of fossil fuels and syngas and the new area of conversions in nonaqueous environments; these areas were discussed in Session 5 and in a Special Topic Discussion Group at the Symposium. In addition, recent developments in bioremediation were well represented in Session 6 and in the poster session. The Symposium involved both the development of new biological agents (such as enzymes or microbes) to carry out targeted conversions as well as bioprocess development. The first area covered improvements in enzymes as well as fundamental insights into substrate-enzyme inter actions and photosynthesis. The latter area focused on converting one material into another using biological agents through combinations of chemical engineering, biological sciences, and fermentation technology. This area also refers to an overall processing involving at least one bio logically catalyzed step in combination with other physical and/ or chemi cal processing operations. Agricultural crops, such as corn and corn fiber as well as woody biomass and lignocellulosic wastes, are emphasized for process feedstocks and their pretreatment investigated.

Enzymes

Author: Robert A. Copeland
Publisher: John Wiley & Sons
ISBN: 0471461857
Format: PDF
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Fully updated and expanded-a solid foundation for understanding experimental enzymology. This practical, up-to-date survey is designed for a broad spectrum of biological and chemical scientists who are beginning to delve into modern enzymology. Enzymes, Second Edition explains the structural complexities of proteins and enzymes and the mechanisms by which enzymes perform their catalytic functions. The book provides illustrative examples from the contemporary literature to guide the reader through concepts and data analysis procedures. Clear, well-written descriptions simplify the complex mathematical treatment of enzyme kinetic data, and numerous citations at the end of each chapter enable the reader to access the primary literature and more in-depth treatments of specific topics. This Second Edition of Enzymes: A Practical Introduction to Structure, Mechanism, and Data Analysis features refined and expanded coverage of many concepts, while retaining the introductory nature of the book. Important new features include: A new chapter on protein-ligand binding equilibria Expanded coverage of chemical mechanisms in enzyme catalysis and experimental measurements of enzyme activity Updated and refined discussions of enzyme inhibitors and multiple substrate reactions Coverage of current practical applications to the study of enzymology Supplemented with appendices providing contact information for suppliers of reagents and equipment for enzyme studies, as well as a survey of useful Internet sites and computer software for enzymatic data analysis, Enzymes, Second Edition is the ultimate practical guide for scientists and students in biochemical, pharmaceutical, biotechnical, medicinal, and agricultural/food-related research.

Industrial Enzymes

Author: Julio Polaina
Publisher: Springer Science & Business Media
ISBN: 1402053770
Format: PDF, Docs
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Recent developments in genetic engineering and protein chemistry are bringing ever more powerful means of analysis to bear on the study of enzyme structure. This volume reviews the most important types of industrial enzymes. In a balanced manner it covers three interrelated aspects of paramount importance for enzyme performance: three-dimensional protein structure, physicochemical and catalytic properties, and the range of both classical and novel applications.

Molecular Biology of the Cell

Author: Bruce Alberts
Publisher: Garland Science
ISBN: 1317563743
Format: PDF, ePub
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As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.