Understanding Enzymes

Author: Allan Svendsen
Publisher: CRC Press
ISBN: 9814669334
Format: PDF
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Understanding Enzymes: Function, Design, Engineering, and Analysis focuses on the understanding of enzyme function and optimization gained in the past decade, past enzyme function analysis, enzyme engineering, and growing insights from the simulation work and nanotechnology measurement of enzymes in action in vitro or in silico. The book also presents new insights into the mechanistic function and understanding of enzyme reactions, as well as touching upon structural characteristics, including X-ray and nuclear magnetic resonance (NMR) structural methods. A major focus of the book is enzyme molecules’ dependency on dynamic and biophysical environmental impacts on their function in ensembles as well as single molecules. A wide range of readers, including academics, professionals, PhD and master’s students, industry experts, and chemists, will immensely benefit from this exclusive book.

Enzyme Functionality

Author: Allan Svendsen
Publisher: CRC Press
ISBN: 0824756916
Format: PDF, ePub, Docs
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Enzyme Functionality serves as a conduit for trailblazing research in enzyme engineering-relating current understanding of sequence families, the new notion of enzyme structure classes, and modern methods in protein engineering, design, and directed evolution to accelerate the development of novel enzyme functionalities. This reference gathers the diverse perspectives of nearly 80 scientists from around the globe and surveys all leading rational and random approaches to the artificial evolution of enzymes. Citing more than 1500 notable works, it outlines assays for enzyme activity, stability, and specificity and a wide variety of site-directed, redesign, and evolutionary engineering methods.

Dioxygen dependent Heme Enzymes

Author: Masao Ikeda-Saito
Publisher: Royal Society of Chemistry
ISBN: 1782629912
Format: PDF, ePub
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This book highlights the many and varied catalytic activities of O2-dependent heme-iron enzymes, including monoxygenases and cytochrome P450, dioxygenases, oxidases and model heme systems required for postgraduate students and researchers in biochemistry and metallobiology.

Directory of Therapeutic Enzymes

Author: Barry M. McGrath
Publisher: CRC Press
ISBN: 1420038370
Format: PDF
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Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product. Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications. The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.

Industrial Enzymes

Author: Julio Polaina
Publisher: Springer Science & Business Media
ISBN: 1402053770
Format: PDF, ePub
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Recent developments in genetic engineering and protein chemistry are bringing ever more powerful means of analysis to bear on the study of enzyme structure. This volume reviews the most important types of industrial enzymes. In a balanced manner it covers three interrelated aspects of paramount importance for enzyme performance: three-dimensional protein structure, physicochemical and catalytic properties, and the range of both classical and novel applications.

Protein Engineering Handbook

Author: Stefan Lutz
Publisher: John Wiley & Sons
ISBN: 3527667016
Format: PDF, Kindle
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Unparalleled in size and scope, this new major reference integrates academic and industrial knowledge into a single resource, allowing for a unique overview of the entire field. Adopting a systematic and practice-oriented approach, and including a wide range of technical and methodological information, this highly accessible handbook is an invaluable 'toolbox' for any bioengineer. In two massive volumes, it covers the full spectrum of current concepts, methods and application areas.

Fundamentals of Food Biotechnology

Author: Byong H. Lee
Publisher: John Wiley & Sons
ISBN: 1118384911
Format: PDF, Kindle
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Food biotechnology is the application of modern biotechnologicaltechniques to the manufacture and processing of food, for examplethrough fermentation of food (which is the oldest biotechnologicalprocess) and food additives, as well as plant and animal cellcultures. New developments in fermentation and enzyme technologicalprocesses, molecular thermodynamics, genetic engineering, proteinengineering, metabolic engineering, bioengineering, and processesinvolving monoclonal antibodies, nanobiotechnology and quorumsensing have introduced exciting new dimensions to foodbiotechnology, a burgeoning field that transcends many scientificdisciplines. Fundamentals of Food Biotechnology, 2nd edition is basedon the author’s 25 years of experience teaching on a foodbiotechnology course at McGill University in Canada. The book willappeal to professional food scientists as well as graduate andadvanced undergraduate students by addressing the latest excitingfood biotechnology research in areas such as genetically modifiedfoods (GMOs), bioenergy, bioplastics, functionalfoods/nutraceuticals, nanobiotechnology, quorum sensing andquenching. In addition, cloning techniques for bacterial and yeastenzymes are included in a “New Trends and Tools”section and selected references, questions and answers appear atthe end of each chapter. This new edition has been comprehensively rewritten andrestructured to reflect the new technologies, products and trendsthat have emerged since the original book. Many new aspectshighlight the short and longer term commercial potential of foodbiotechnology.

International Space Station

Author: G. Haskell
Publisher: Springer Science & Business Media
ISBN: 9401142599
Format: PDF, ePub, Docs
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G. Haskell, Symposium Programme Committee Chair, Vice President, Administration and Programme Development, International Space University e-mail: [email protected] M. Rycroft, Faculty Member, International Space University e-mail: [email protected] The theme of the fourth annual symposium arranged by the International Space University (ISU) was "International Space Station: The Next Space Marketplace". The Symposium covered this topic from the uniqu- interdisciplinary, international and intercultural - perspectives of ISU. It focussed on significant issues related to policy, innovative management, commerce, regulation, education and outreach rather than concentrating on engineering and scientific issues. Although admirable progress has already been made in defining the utilisation of the International Space Station (ISS) in its early operational phases, what does the future hold? What important new applications will arise? What commercial opportunities may emerge? And how will the political, legal and financial hurdles be overcome, not to mention the technical challenges? The aim of the Symposium was to discuss such questions and draw out new ways of using the Space Station in the future. Among the 120 attendees were members of the fourth Master of Space Studies class, young professionals and postgraduate students who are developing the Symposium's theme in their Team Project. Their comprehensive overview of the subject is presented as an Annex here. Their final report on the Team Project will be completed at the end of July 1999, and published separately.