Viral Pathogenesis and Immunity

Author: Neal Nathanson
Publisher: Elsevier
ISBN: 9780080471051
Format: PDF, ePub
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Based on the highly successful reference work Viral Pathogenesis published in 1997, this concise, economical version can be used both as an introductory text or for self-education by medical students and biologists alike. This latest edition provides a completely revised overview of the subject with new chapters on innate immunity, emerging viral diseases, and antiviral therapy in a format that is easy to understand without continually referring to additional information. Used by the author in his graduate classes at the University of Pennsylvania, it sets forth the essential principles and discusses the details of how the immune system responds to viral invasion including the treatment and prevention of infection. Illustrated by pertinent examples it is one of the only books devoted exclusively to this topic. * Offers almost a 20% expansion over the first edition * Focuses specifically on viral pathogenesis unlike other texts where only a few chapters are devoted to the topic * Neal Nathanson is one of the primary authorities in the field and has authored chapters on viral pathogenesis in two of the most well known virology and microbiology titles Field's Virology and Topley and Wilson's Microbiology * Now in four color throughout!

Viral Pathogenesis

Author: Michael G. Katze
Publisher: Academic Press
ISBN: 0128011742
Format: PDF, Mobi
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Viral Pathogenesis: From Basics to Systems Biology, Third Edition, has been thoroughly updated to cover topical advances in the evolving field of viral pathogenesis, while also providing the requisite classic foundational information for which it is recognized. The book provides key coverage of the newfound ability to profile molecular events on a system-wide scale, which has led to a deeper understanding of virus-host interactions, host signaling and molecular-interaction networks, and the role of host genetics in determining disease outcome. In addition, the content has been augmented with short chapters on seminal breakthroughs and profiles of their progenitors, as well as short commentaries on important or controversial issues in the field. Thus, the reader will be given a view of virology research with perspectives on issues such as biomedical ethics, public health policy, and human health. In summary, the third edition will give the student a sense of the exciting new perspectives on viral pathogenesis that have been provided by recent developments in genomics, computation, modeling, and systems biology. Covers all aspects of viral infection, including viral entry, replication, and release, as well as innate and adaptive immunity and viral pathogenesis Provides a fresh perspective on the approaches used to understand how viruses cause disease Features molecular profiling techniques, whole genome sequencing, and innovative computational methods Highlights the use of contemporary approaches and the insights they provide to the field

Immunologie

Author: Charles A. Janeway
Publisher: Spektrum Akademischer Verlag
ISBN: 9783827410795
Format: PDF, ePub, Mobi
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Das Standardlehrbuch der Immunologie im deutschen Raum liegt nun erneut in einer vollstAndig A1/4berarbeiteten und aktualisierten Form vor. Der "Janeway" bleibt damit ein hochaktueller und verlAsslicher Begleiter im unverAndert rasant fortschreitenden Fachgebiet der Immunologie. ”Dieses Buch setzt eindeutig neue MaAstAbe.Immunology Today" ”... so aktuell, wie ein Lehrbuch nur sein kann.The New England Journal of Medicine" ”... eine anschauliche, lebendige und verlAAliche EinfA1/4hrung in das gesamte Gebiet der Immunbiologie.Cell" ”Unter den Immunologie-LehrbA1/4chern nimmt dieses sicher heute den vorderen Rang ein. Es macht VergnA1/4gen, sich von ihm bilden zu lassen.Biospektrum" ”Die Texte erklAren die komplizierte Materie in einer klaren und anschaulichen Sprache ... Das Buch eignet sich hervorragend als Lehrbuch und als Nachschlagewerk fA1/4r jeden, der sich mit Fragen der Immunologie beschAftigt.Deutsche Apotheker Zeitung" ”Dieses neue Lehrbuch aus dem Spektrum-Verlag ist sicherlich das zur Zeit umfassendste, aktuellste und didaktisch sinnvollste Werk zum Thema Immunologie, das in deutscher Sprache auf dem Markt und zu einem vernA1/4nftigen Preis zu erwerben ist.Curare" ”Kann uneingeschrAnkt jedem Medizinstudenten und jedem klinisch tAtigen Kollegen empfohlen werden.Prof. M. Seyfarth, UniversitAt LA1/4beck"”Das Buch deckt die moderne Immunologie in ihrer ganzen Vielfalt ab. Trotzdem wirken Text und Darstellungen wie aus einem GuA.Prof. Th. HA1/4nig, UniversitAt WA1/4rzburg" ”Das Lehrbuch "Immunologie" von Janeway und Travers ist hochaktuell und A1/4berdies exzellent illustriert. Das Gesamtkonzept ist ... sehr gut auf die BedA1/4rfnisse von Biologie- und Medizinstudenten zugeschnitten.Prof. W. DrAge, DKFZ Heidelberg" ”Dieses Buch zeigt, wie man das komplexe Wissensgebiet der Immunologie klar und verstAndlich beschreiben kann und den Leser gleichzeitig zur kritischen Beurteilung der aktuellen Forschung befAhigt.Prof. Dr. N. Koch, UniversitAt Bonn" ”Das Buch ersetzt in hervorragender Weise eine leider noch nicht etablierte Pflichtvorlesung fA1/4r Mediziner und Biologen.Prof. G. Uhlenbruck, UniversitAt KAln" ” ... ein modernes und kompaktes Lehrbuch, das man bedenkenlos allen jungen Medizinern und Biologen, Studenten, Doktoranden und Post-Docs, die sich mit Fragen der Immunologie beschAftigen wollen oder beschAftigen, empfehlen kann.Prof. Klaus Rajewsky im Vorwort zur deutschen Ausgabe"

Concepts in Viral Pathogenesis

Author: A. L. Notkins
Publisher: Springer Science & Business Media
ISBN: 1461252504
Format: PDF, Docs
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The current proliferation of scientific information makes it difficult for even the most diligent reader to keep up with the latest developments in his/her own field, let alone other areas of interest. Review articles are one solution, but they too have become so voluminous and detailed that they often defeat the purpose for which they were intended. We have attempted to ease this problem by using a different format. In this volume on Concepts in Viral Pathogenesis, we have assembled a series of mini-reviews/editorials, 1,000 to 2,000 words in length. Each is a pithy distil lation of the state-of-the-art with emphasis on current thinking and unifying concepts rather than a compendium of the literature. The 53 articles, all written by active workers in their respective fields, are organized systemati cally so that the book will provide busy investigators, teachers and students of up-to-date information in a very brief and easily read a conceptual core able form. In addition, the authors have attempted to identify unresolved problems and point to future directions.

The Flaviviruses Pathogenesis and Immunity

Author:
Publisher: Elsevier
ISBN: 0080493823
Format: PDF, ePub, Docs
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Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Pathogenesis and Immunity, the second volume of The Flaviviruses, examines the processes by which the flaviviruses cause disease, the different cytopathic effects and the associated immunopathological responses produced in their hosts. * Comprehensive approach to the scientific disciplines needed to unravle the complexities of virus-host interactions. * New, detailed information on the pathogenesis and immunology of the Flavivirus family. * Descibes the technologies that have contributed to our current knowledge about the Flaviviruses. * Identifies the major problems faced in attempting to further understand the virus-host interactions that result in disease. * An exhaustive compendium of current and past knowledge on the Flavivirus family

West Nile Encephalitis Virus Infection

Author: Michael S. Diamond
Publisher: Springer Science & Business Media
ISBN: 9780387798400
Format: PDF, ePub, Docs
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West Nile virus is a neurotropic flavivirus that has emerged globally as a primary cause of viral encephalitis. Infection of humans and other vertebrate animals is associated with a febrile illness that can progress to a lethal encephalitis or flaccid paralysis syndrome. Its appearance in the Western Hemisphere in 1999 and the corresponding increase in global disease burden over the last decade have been accompanied by intensive study, including the entry of many scientists into the field. Breakthroughs have been made in understanding the unique transmission pattern between the vector and the multiple avian and mammalian hosts and targets. Studies in mammalian systems have dissected the viral and host factors that determine the pathogenesis and outcome of West Nile virus infection. On the basis of these experiments, progress has been made on the identification of genetic factors that predispose to severe human disease. Thus, in a remarkably short period of time, insight has been gained on a wide variety of disciplines related to West Nile virus biology. The aim of this book was to assemble an up-to-date and cutti- edge anthology from the leading experts in the field. The chapters are balanced by submissions from newcomers who have made significant recent contributions with those from established investigators who have dedicated their careers to the study of West Nile virus.

Viral Pathogenesis in Diagrams

Author: Hans-Wolfgang Ackermann
Publisher: CRC Press
ISBN: 9781420039115
Format: PDF, Mobi
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Viral Pathogenesis in Diagrams is the first book of its kind to illustrate viral pathogenesis on a comparative basis. The text covers the pathogenesis of viral diseases, including vertebrates, invertebrates, plants, and protists. The diagrams summarize and integrate large numbers of observations, from electron microscopy to clinical data, into a single picture or a few related drawings. Organized alphabetically by virus family or groups, this book covers the complete domain of virology. Transcending photographs and experimental data, the diagrams are ideally suited to illustrate the pathogenesis of viral diseases, from infection to host defenses and cell death. Included are two chapters describing general pathogenesis in vertebrate virus infections and illustrating the spread of viruses through the body, as well as cytopathology and host defenses. One chapter illustrates the pathogenic behavior of 19 vertebrate virus families, especially herpesviruses and retroviruses. The 268 diagrams in Viral Pathogenesis in Diagrams were selected from over 800 diagrams of English and French virological literature, including one derived from a famous drawing by Leonardo da Vinci. This up-to-date reference will promote understanding and future research.

Modulation of Host Gene Expression and Innate Immunity by Viruses

Author: Peter Palese
Publisher: Springer Science & Business Media
ISBN: 1402032420
Format: PDF, Mobi
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This book is an excellent, up-to-date reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Thus, the book will be of great interest to virologists, molecular immunologists and biologists, and biochemists but also to clinical pharmacologists in the long-term search for new antiviral agents. Ulrich Desselberger, Gif-sur-Yvette/Cambridge. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases. Pharmaceutical industry professionals will also find interest in this illuminating look into virus/host interactions.